Publications






Sitagliptin but not alpha glucosidase inhibitor reduced the serum soluble CD163, a marker for activated macrophage, in individuals with type 2 diabetes mellitus.
Diabetes Res Clin Pract 2017 Apr 16;126:138-143. Epub 2017 Feb 16.
Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8670, Japan; Department of Medicine, Division of Diabetes, Metabolism and Endocrinology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8670, Japan.





Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial.
Atherosclerosis 2016 Jun 26;249:36-43. Epub 2016 Feb 26.
Laboratory for Systems Biology and Medicine (LSBM), Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904, Japan. Electronic address:


Cushing Syndrome Due to ACTH-Secreting Pheochromocytoma, Aggravated by Glucocorticoid-Driven Positive-Feedback Loop.
J Clin Endocrinol Metab 2016 Mar 23;101(3):841-6. Epub 2015 Dec 23.
Department of Clinical Cell Biology and Medicine (I.S., S.H., M.F., T.Tak., A.T., T.K., E.K., A.S., H.N., N.H., S.S., T.M., H.K., K.Y., T.Tan.), Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan; Division of Diabetes, Endocrinology, and Metabolism (I.S., S.H., M.F., T.Tak., A.T., T.K., E.K., A.S., H.N., N.H., S.S., T.M., H.K., K.Y., T.Tan.), Chiba University Hospital, Chiba 260-8670, Japan; Department of Pathology (K.O., H.S.), Tohoku University Graduate School of Medicine, Sendai City, Miyagi 980-8575, Japan; and Center for Diabetes, Metabolism, and Endocrinology (I.T.), Toho University Sakura Medical Center, Sakura, Chiba 285-0841, Japan.




Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1.
Cell Rep 2015 Aug 30;12(6):1042-55. Epub 2015 Jul 30.
Department of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana Chuo-ku, Chiba 260-8670, Japan; AMED-CREST, AMED, 1-8-1 Inohana Chuo-ku, Chiba 260-8670, Japan. Electronic address:


Pioglitazone improves fat tissue distribution and hyperglycemia in a case of cockayne syndrome with diabetes.
Diabetes Care 2015 May;38(5):e76
Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, Chuo-ku, Chiba-shi, Chiba, Japan Department of Medicine, Division of Diabetes, Metabolism and Endocrinology, Chiba University Hospital, Chuo-ku, Chiba-shi, Chiba, Japan.

Comparison in decision-making between bulimia nervosa, anorexia nervosa, and healthy women: influence of mood status and pathological eating concerns.
J Eat Disord 2015 2;3:14. Epub 2015 Apr 2.
United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Suita, Japan ; Research Center for Child Mental Development, Graduate School of Medicine, Chiba University, Chiba, Japan ; Department of Child Psychiatry, Graduate School of Medicine, Chiba University, Chiba, Japan.


Pituitary adenylate cyclase-activating polypeptide protects glomerular podocytes from inflammatory injuries.
J Diabetes Res 2015 2;2015:727152. Epub 2015 Mar 2.
Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, Japan ; Division of Diabetes, Metabolism and Endocrinology, Chiba University Hospital, Japan.









Tetraspanin CD9 modulates ADAM17-mediated shedding of LR11 in leukocytes.
Exp Mol Med 2014 Apr 4;46:e89. Epub 2014 Apr 4.
1] Department of Hematology, Chiba University Hospital, Chiba, Japan [2] Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan.

Werner syndrome with refractory cystoid macular edema and immunohistochemical analysis of WRN proteins in human retinas.
BMC Ophthalmol 2014 Mar 12;14:31. Epub 2014 Mar 12.
Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Inohana 1-8-1, Chuo-ku, Chiba 260-8670, Chiba, Japan.







Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.
J Exp Med 2013 Nov 11;210(12):2627-39. Epub 2013 Nov 11.
Department of Cellular and Molecular Medicine and 2 Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.





Atorvastatin ameliorates podocyte injury in patients with type 2 diabetes complicated with dyslipidemia.
Diabetes Res Clin Pract 2013 Apr 10;100(1):e26-9. Epub 2013 Jan 10.
Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8670, Japan.


The reduced form of coenzyme Q10 improves glycemic control in patients with type 2 diabetes: an open label pilot study.
Biofactors 2012 Nov-Dec;38(6):416-21. Epub 2012 Aug 8.
Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-Ku, Chiba-Shi, Chiba 260-8670, Japan.

Multicenter study to determine the diagnosis criteria of heterozygous familial hypercholesterolemia in Japan.
J Atheroscler Thromb 2012 25;19(11):1019-26. Epub 2012 Oct 25.
Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.

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