Publications by authors named "Kourosh Saeb-Parsy"

71Publications

Regulatory T Cell Therapy Following Liver Transplantation.

Liver Transpl 2020 Nov 22. Epub 2020 Nov 22.

Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

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http://dx.doi.org/10.1002/lt.25948DOI Listing
November 2020

Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2.

Cell Stem Cell 2020 Oct 21. Epub 2020 Oct 21.

Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 A0W, UK; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EL, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2020.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577700PMC
October 2020

Mitochondria as Therapeutic Targets in Transplantation.

Trends Mol Med 2020 Sep 17. Epub 2020 Sep 17.

Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK; Medical Research Council (MRC) Mitochondrial Biology Unit, Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2020.08.001DOI Listing
September 2020

Opportunities and Challenges in Using Social Media in Organ Donation.

JAMA Surg 2020 Sep;155(9):797-798

Department of Transplantation, Royal Free London NHS Foundation Trust, Hampstead, London, United Kingdom.

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http://dx.doi.org/10.1001/jamasurg.2020.0791DOI Listing
September 2020

Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury.

Redox Biol 2020 Sep 12;36:101640. Epub 2020 Jul 12.

Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2020.101640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372157PMC
September 2020

B Lymphocyte-Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury.

J Immunol 2020 Sep 31;205(5):1376-1384. Epub 2020 Jul 31.

Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.2000454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444279PMC
September 2020

Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker.

Mol Pharm 2020 09 5;17(9):3526-3540. Epub 2020 Aug 5.

Molecular Research Center, Mitochondrial Biology Unit, Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1021/acs.molpharmaceut.0c00533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482397PMC
September 2020

Opportunities and Challenges in Using Social Media in Organ Donation.

JAMA Surg 2020 Jun 17. Epub 2020 Jun 17.

Department of Transplantation, Royal Free London NHS Foundation Trust, Hampstead, London, United Kingdom.

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http://dx.doi.org/10.1001/jamasurg.2020.0791DOI Listing
June 2020

The Role of Ischemia/Reperfusion Injury in Early Hepatic Allograft Dysfunction.

Liver Transpl 2020 08;26(8):1034-1048

Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

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http://dx.doi.org/10.1002/lt.25779DOI Listing
August 2020

Development of an objective, standardized tool for surgical assessment of deceased donor kidneys: The Cambridge Kidney Assessment Tool.

Clin Transplant 2020 02 29;34(2):e13782. Epub 2020 Jan 29.

Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/ctr.13782DOI Listing
February 2020

Recent Advancements and Applications of Human Immune System Mice in Preclinical Immuno-Oncology.

Toxicol Pathol 2020 02 18;48(2):302-316. Epub 2019 Dec 18.

Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Campus, Cambridge, United Kingdom.

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http://dx.doi.org/10.1177/0192623319886304DOI Listing
February 2020

Phenotypically distinct neutrophils patrol uninfected human and mouse lymph nodes.

Proc Natl Acad Sci U S A 2019 09 4;116(38):19083-19089. Epub 2019 Sep 4.

Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge CB2 0QH, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1905054116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754587PMC
September 2019

Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue.

Nat Protoc 2019 06 20;14(6):1884-1925. Epub 2019 May 20.

Wellcome Trust-Medical Research Council Stem Cell Institute, Cambridge Stem Cell Institute, Anne McLaren Laboratory, Department of Surgery, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/s41596-019-0168-0DOI Listing
June 2019

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Immunity 2019 04 12;50(4):1099-1114.e10. Epub 2019 Mar 12.

Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge CB2 0QH, UK; Cellular Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinton CB10 1SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477154PMC
April 2019

Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold.

Biomaterials 2018 11 27;182:299-311. Epub 2018 Jul 27.

Centre for Stem Cells and Regenerative Medicine & Institute for Liver Studies, King's College London, England, UK; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.07.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131727PMC
November 2018

Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury.

Pediatr Nephrol 2019 07 2;34(7):1167-1174. Epub 2018 Jun 2.

Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 2QQ, UK.

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http://dx.doi.org/10.1007/s00467-018-3984-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366561PMC
July 2019

Advances in the generation of bioengineered bile ducts.

Biochim Biophys Acta Mol Basis Dis 2018 04 31;1864(4 Pt B):1532-1538. Epub 2017 Oct 31.

Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK; Wellcome Trust-Medical Research Council Stem Cell Institute, Cambridge Stem Cell Institute, Anne McLaren Laboratory, University of Cambridge, Cambridge, UK; Department of Hepatology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.10.034DOI Listing
April 2018

Engaging Cold to Upregulate Cell Proliferation in Alginate-Encapsulated Liver Spheroids.

Tissue Eng Part C Methods 2017 08 20;23(8):455-464. Epub 2017 Jul 20.

1 Asymptote Ltd. , Cambridge, United Kingdom .

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http://dx.doi.org/10.1089/ten.tec.2017.0131DOI Listing
August 2017

An analysis of the survival outcomes of simultaneous pancreas and kidney transplantation compared to live donor kidney transplantation in patients with type 1 diabetes: a UK Transplant Registry study.

Transpl Int 2017 Sep 2;30(9):884-892. Epub 2017 May 2.

Department of Surgery and NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/tri.12957DOI Listing
September 2017

Ureteric complications in recipients of kidneys from donation after circulatory death donors.

Clin Transplant 2017 04 13;31(4). Epub 2017 Feb 13.

Department of Surgery, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/ctr.12912DOI Listing
April 2017

A single-centre experience of Roux-en-Y enteric drainage for pancreas transplantation.

Transpl Int 2017 Apr 2;30(4):410-419. Epub 2017 Mar 2.

Department of Surgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/tri.12920DOI Listing
April 2017

Diversity of the CD4 T Cell Alloresponse: The Short and the Long of It.

Cell Rep 2016 Feb 21;14(5):1232-1245. Epub 2016 Jan 21.

University of Cambridge, School of Clinical Medicine, Cambridge CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405053PMC
February 2016

A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury.

Cell Metab 2016 Feb 14;23(2):254-63. Epub 2016 Jan 14.

MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.12.009DOI Listing
February 2016

Transplanting suboptimum organs: medico-legal implications.

Lancet 2015 Aug;386(9995):719-21

Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK; NIHR Cambridge Biomedical Research Centre, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(15)61413-1DOI Listing
August 2015

The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model.

J Heart Lung Transplant 2015 Nov 11;34(11):1471-80. Epub 2015 Jun 11.

Department of Surgery, University of Cambridge, and the National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/j.healun.2015.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626443PMC
November 2015

Protection against renal ischemia-reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ.

Redox Biol 2015 Aug 29;5:163-168. Epub 2015 Apr 29.

Medical Research Council Mitochondrial Biology Unit, Cambridge BioMedical Campus, Hills Road, Cambridge CB2 0XY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2015.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427662PMC
August 2015

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease.

Blood 2014 May 1;123(20):3139-51. Epub 2014 Apr 1.

Cambridge Institute for Medical Research and Wellcome Trust/Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom; Department of Haematology, University of Cambridge, United Kingdom; Department of Haematology, Addenbrooke's Hospital, Cambridge, United Kingdom;

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-06-51
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http://dx.doi.org/10.1182/blood-2013-06-510222DOI Listing
May 2014

The discard of deceased donor kidneys in the UK.

Clin Transplant 2014 Mar 8;28(3):345-53. Epub 2014 Feb 8.

Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK.

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http://doi.wiley.com/10.1111/ctr.12319
Publisher Site
http://dx.doi.org/10.1111/ctr.12319DOI Listing
March 2014

BAFF and associated TNF superfamily members in renal transplantation: an end to BLySful ignorance.

Transplantation 2013 Nov;96(10):853-9

1 Department of Surgery, University of Cambridge, Cambridge, UK. 2 Address correspondence to: Dr. Gavin J. Pettigrew, Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Box 202, Level 9, Hills Road, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1097/TP.0b013e3182997d34DOI Listing
November 2013

Unlinked memory helper responses promote long-lasting humoral alloimmunity.

J Immunol 2012 Dec 16;189(12):5703-12. Epub 2012 Nov 16.

Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1202257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788591PMC
December 2012

Antiplatelet therapy in transplantation: new tricks from old drugs?

Transplantation 2009 Mar;87(5):633-5

Department of Surgery, University of Cambridge, United Kingdom.

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http://dx.doi.org/10.1097/TP.0b013e3181963208DOI Listing
March 2009

Mesothelioma with non-pleural malignancy: a red herring or just an uncommon pairing?

J Cardiothorac Surg 2006 Nov 1;1:39. Epub 2006 Nov 1.

Papworth Hospital, Papworth Everard, Cambridge CB3 8RE, UK.

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http://dx.doi.org/10.1186/1749-8090-1-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636046PMC
November 2006

The use of vacuum-assisted closure in the treatment of post-transplant wound infections: a case series.

J Heart Lung Transplant 2005 Sep;24(9):1444

Transplant Unit, Papworth Hospital, Papworth Everard, Cambridgeshire, United Kingdom.

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http://dx.doi.org/10.1016/j.healun.2004.12.111DOI Listing
September 2005