Kouros Owzar

Kouros Owzar

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fastJT: An R package for robust and efficient feature selection for machine learning and genome-wide association studies.

BMC Bioinformatics 2019 Jun 13;20(1):333. Epub 2019 Jun 13.

Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1186/s12859-019-2869-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567636PMC
June 2019

Efficient estimation of grouped survival models.

BMC Bioinformatics 2019 May 28;20(1):269. Epub 2019 May 28.

Department of Biostatistics and Bioinformatics, Duke University, Durham, USA.

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http://dx.doi.org/10.1186/s12859-019-2899-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540566PMC
May 2019

Sample size calculation for studies with grouped survival data.

Stat Med 2018 Nov 10;37(27):3904-3917. Epub 2018 Jun 10.

Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1002/sim.7847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262878PMC
November 2018

Mapping eQTL by leveraging multiple tissues and DNA methylation.

BMC Bioinformatics 2017 Oct 18;18(1):455. Epub 2017 Oct 18.

Program in Computational Biology and Bioinformatics, Duke University, 2424 Erwin Road, Suite 1104, Durham, 27710, NC, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12859-017-1856-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648503PMC
October 2017

Facilitating the Calculation of the Efficient Score Using Symbolic Computing.

Am Stat 2018 30;72(2):199-205. Epub 2017 Oct 30.

Biostatistics and Bioinformatics, Duke University School of Medicine Duke Cancer Institute, Duke University Medical Center.

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http://dx.doi.org/10.1080/00031305.2017.1392361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092959PMC
October 2017

Identification of a DNA Damage-Induced Alternative Splicing Pathway That Regulates p53 and Cellular Senescence Markers.

Cancer Discov 2017 07 13;7(7):766-781. Epub 2017 Mar 13.

Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501752PMC
July 2017

Apoptotic capacity and risk of squamous cell carcinoma of the head and neck.

Eur J Cancer 2017 02 26;72:166-176. Epub 2016 Dec 26.

Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287407PMC
February 2017

Targeted Exome Sequencing of the Cancer Genome in Patients with Very High-risk Bladder Cancer.

Eur Urol 2016 11 9;70(5):714-717. Epub 2016 Aug 9.

Division of Urology, Department of Surgery, Duke University, Durham, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2016.07.049DOI Listing
November 2016

Fitting Cox Models with Doubly Censored Data Using Spline-Based Sieve Marginal Likelihood.

Scand Stat Theory Appl 2016 Jun 23;43(2):476-486. Epub 2015 Nov 23.

Department of Biostatistics and Bioinformatics, Duke University.

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http://dx.doi.org/10.1111/sjos.12186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879632PMC
June 2016

Exploiting expression patterns across multiple tissues to map expression quantitative trait loci.

BMC Bioinformatics 2016 Jun 24;17:257. Epub 2016 Jun 24.

Program in Computational Biology and Bioinformatics, Duke University, 101 Science Dr, Durham, 27708, USA.

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http://dx.doi.org/10.1186/s12859-016-1123-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919894PMC
June 2016

Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncology)/Blood and Marrow Transplant Clinical Trial Network 0502.

J Clin Oncol 2015 Dec 2;33(35):4167-75. Epub 2015 Nov 2.

Steven M. Devine and William Blum, Ohio State University, Columbus, OH; Kouros Owzar, Flora Mulkey, Vera Hars, and Alexander B. Sibley, Alliance Statistics and Data Center, Duke University, Durham; Thomas C. Shea, University of North Carolina, Chapel Hill, NC; Richard M. Stone, Robert J. Soiffer, and Edwin P. Alyea, Dana-Farber Cancer Institute; Yi-Bin Chen, Massachusetts General Hospital, Boston, MA; Jack W. Hsu, University of Florida, Gainesville, FL; Richard E. Champlin, MD Anderson Cancer Research Center, Houston, TX; Ravi Vij, Washington University, St. Louis, MO; James Slack, Mayo Clinic, Scottsdale, AZ; Richard A. Larson, University of Chicago, Chicago, IL; Sergio Giralt, Memorial Sloan Kettering Cancer Center, New York, NY; Shelly Carter, The EMMES Corporation, Bethesda, MD; Mary M. Horowitz, Medical College of Wisconsin, Milwaukee, WI; and Charles Linker, University of California at San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2015.62.7273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658453PMC
December 2015

Participation in Cancer Pharmacogenomic Studies: A Study of 8456 Patients Registered to Clinical Trials in the Cancer and Leukemia Group B (Alliance).

J Natl Cancer Inst 2015 Oct 9;107(10). Epub 2015 Jul 9.

Personalized Medicine, Mission Cancer Care, Mission Health, Asheville, NC (LGD); Biostatistics Core, Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina, Chapel Hill, NC (AMD); Alliance Statistics and Data Center, Duke University, Durham, NC (formerly the Cancer and Leukemia Group B Statistical and Data Management Center, Duke University, Durham, NC) (KO); GlaxoSmithKline, Research Triangle Park, NC (DW); Independent contractor, Williamsville, NY (KD); Department of Medicine and Center for Personalized Therapeutics, University of Chicago, Chicago, IL (PNF, MJR); DeBartolo Family Personalized Medicine Institute, Moffitt Cancer Center, Tampa, FL (HLM).

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http://jnci.oxfordjournals.org/content/107/10/djv188.full.pd
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv18
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http://dx.doi.org/10.1093/jnci/djv188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758036PMC
October 2015

Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma.

Gynecol Oncol 2015 Oct 7;139(1):23-9. Epub 2015 Aug 7.

Division of Gynecology Oncology, Department of Obstetrics and Gynecology, Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2015.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587300PMC
October 2015

Incorporating Functional Information in Tests of Excess De Novo Mutational Load.

Am J Hum Genet 2015 Aug 30;97(2):272-83. Epub 2015 Jul 30.

Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573447PMC
August 2015

Functional FLT1 Genetic Variation is a Prognostic Factor for Recurrence in Stage I-III Non-Small-Cell Lung Cancer.

J Thorac Oncol 2015 Jul;10(7):1067-75

*Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina; †Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia; ‡Department of Genetics, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; §Molecular Oncology Laboratory, General University Hospital Research Foundation, Valencia, Spain; ‖Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina; ¶Department of Medicine, University of Chicago, Chicago, Illinois; #Department of Pediatrics, University of Illinois at Chicago, Chicago, Illinois; **Department of Thoracic Surgery, and ††Department of Oncology and Radiotherapy, Medical University of Gdansk, Gdansk, Poland; ‡‡Department of Medicine, University of Colorado Cancer Center, Aurora, Colorado; §§Department of Medicine, University of Valencia, Valencia, Spain; ‖‖Department of Oncology, General University Hospital of Valencia, Valencia, Spain; and ¶¶Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1097/JTO.0000000000000549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494119PMC
July 2015

Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).

Redox Biol 2014 9;2:400-10. Epub 2014 Jan 9.

Department of Radiation Oncology, Duke University School of Medicine, Durham, NC 27710, USA ; Division of Translational Radiation Sciences, Department of Radiation Oncology, University of Maryland, 655W Baltimore Street, Bressler Research Building, 8-025, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1016/j.redox.2013.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949096PMC
June 2015

Next generation distributed computing for cancer research.

Cancer Inform 2014 27;13(Suppl 7):97-109. Epub 2015 Apr 27.

Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA. ; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.4137/CIN.S16344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412427PMC
May 2015

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.

Authors:
Brian M Wolpin Cosmeri Rizzato Peter Kraft Charles Kooperberg Gloria M Petersen Zhaoming Wang Alan A Arslan Laura Beane-Freeman Paige M Bracci Julie Buring Federico Canzian Eric J Duell Steven Gallinger Graham G Giles Gary E Goodman Phyllis J Goodman Eric J Jacobs Aruna Kamineni Alison P Klein Laurence N Kolonel Matthew H Kulke Donghui Li Núria Malats Sara H Olson Harvey A Risch Howard D Sesso Kala Visvanathan Emily White Wei Zheng Christian C Abnet Demetrius Albanes Gabriella Andreotti Melissa A Austin Richard Barfield Daniela Basso Sonja I Berndt Marie-Christine Boutron-Ruault Michelle Brotzman Markus W Büchler H Bas Bueno-de-Mesquita Peter Bugert Laurie Burdette Daniele Campa Neil E Caporaso Gabriele Capurso Charles Chung Michelle Cotterchio Eithne Costello Joanne Elena Niccola Funel J Michael Gaziano Nathalia A Giese Edward L Giovannucci Michael Goggins Megan J Gorman Myron Gross Christopher A Haiman Manal Hassan Kathy J Helzlsouer Brian E Henderson Elizabeth A Holly Nan Hu David J Hunter Federico Innocenti Mazda Jenab Rudolf Kaaks Timothy J Key Kay-Tee Khaw Eric A Klein Manolis Kogevinas Vittorio Krogh Juozas Kupcinskas Robert C Kurtz Andrea LaCroix Maria T Landi Stefano Landi Loic Le Marchand Andrea Mambrini Satu Mannisto Roger L Milne Yusuke Nakamura Ann L Oberg Kouros Owzar Alpa V Patel Petra H M Peeters Ulrike Peters Raffaele Pezzilli Ada Piepoli Miquel Porta Francisco X Real Elio Riboli Nathaniel Rothman Aldo Scarpa Xiao-Ou Shu Debra T Silverman Pavel Soucek Malin Sund Renata Talar-Wojnarowska Philip R Taylor George E Theodoropoulos Mark Thornquist Anne Tjønneland Geoffrey S Tobias Dimitrios Trichopoulos Pavel Vodicka Jean Wactawski-Wende Nicolas Wentzensen Chen Wu Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Robert Hoover Patricia Hartge Charles Fuchs Stephen J Chanock Rachael S Stolzenberg-Solomon Laufey T Amundadottir

Nat Genet 2014 Sep 3;46(9):994-1000. Epub 2014 Aug 3.

1] Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. [2].

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http://dx.doi.org/10.1038/ng.3052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191666PMC
September 2014

25-Hydroxyvitamin D levels and survival in advanced pancreatic cancer: findings from CALGB 80303 (Alliance).

J Natl Cancer Inst 2014 Aug 6;106(8). Epub 2014 Aug 6.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA (KVL, APV); Department of Biostatistics and Bioinformatics, Duke University, Durham, NC (KO, DN); Alliance Statistics and Data Center, Duke University, Durham, NC (KO, CJ, DN); The University of Chicago Medical Center, Chicago, IL (HLK); Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL (MFM); Memorial Sloan-Kettering Cancer Center, New York, NY (EMO); Dana-Farber Cancer Institute, Boston, MA (CF); University of North Carolina Institute for Pharmacogenomics and Individualized Therapy, Eshelman School of Pharmacy, School of Medicine, Lineberger Comprehensive Cancer Center, Chapel Hill, NC (FI).

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http://dx.doi.org/10.1093/jnci/dju185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155431PMC
August 2014

Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial.

J Clin Oncol 2014 May 17;32(15):1563-70. Epub 2014 Mar 17.

Christopher L. Corless, Violetta Kolesnikova, Charles D. Blanke, Michael C. Heinrich, Oregon Health and Science University, Portland, OR; Karla V. Ballman, Mayo Clinic, Rochester, MN; Cristina R. Antonescu and Ronald P. DeMatteo, Memorial Sloan-Kettering Cancer Center; Robert G. Maki, Mt Sinai School of Medicine, New York, NY; Peter W.T. Pisters and Shreyaskumar Patel, University of Texas MD Anderson Cancer Center, Houston, TX; Martin E. Blackstein, Mount Sinai Hospital, Toronto, Ontario, Canada; George D. Demetri, Dana-Farber Cancer Institute, Boston, MA; Margaret von Mehren, Fox Chase Cancer Institute, Philadelphia, PA; Martin D. McCarter, University of Colorado School of Medicine, Aurora, CO; and Kouros Owzar, Duke University School of Medicine, Durham, NC.

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http://ascopubs.org/doi/10.1200/JCO.2013.51.2046
Publisher Site
http://dx.doi.org/10.1200/JCO.2013.51.2046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026579PMC
May 2014

Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.

Genes Dev 2014 May;28(9):995-1004

Department of Pharmacology, University of California at San Diego School of Medicine, La Jolla, California 92093, USA;

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http://dx.doi.org/10.1101/gad.231944.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018497PMC
May 2014

A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.

Pharmacogenet Genomics 2014 Feb;24(2):129-32

aDepartment of Medicine, The University of Chicago, Chicago, Illinois bDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901533PMC
February 2014

MicroRNA expression differentiates squamous epithelium from Barrett's esophagus and esophageal cancer.

Dig Dis Sci 2013 Nov 8;58(11):3178-88. Epub 2013 Aug 8.

Division of Gastroenterology, Department of Medicine, Duke University, DUMC 3913, Durham, NC, 27710, USA,

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http://dx.doi.org/10.1007/s10620-013-2806-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180409PMC
November 2013

Long-term results of adjuvant imatinib mesylate in localized, high-risk, primary gastrointestinal stromal tumor: ACOSOG Z9000 (Alliance) intergroup phase 2 trial.

Ann Surg 2013 Sep;258(3):422-9

*Memorial Sloan-Kettering Cancer Center, New York, NY †Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN ‡Oregon Health Sciences University, Portland, OR §Fox Chase Cancer Center, Philadelphia, PA ¶University of Colorado School of Medicine, Aurora, CO ‖Stanford University School of Medicine, Stanford CA **Mt Sinai School of Medicine, New York, NY ††University of Texas MD Anderson Cancer Center, Houston, TX ‡‡Dana Farber Cancer Institute, Boston, MA; and §§Alliance Statistics and Data Center, Duke University, Durham, NC.

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http://dx.doi.org/10.1097/SLA.0b013e3182a15eb7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041735PMC
September 2013

Gastric cancer pharmacogenetics: progress or old tripe?

Pharmacogenomics 2013 Jul;14(9):1053-64

UNC Institute for Pharmacogenomics & Individualized Therapy, University of North Carolina, Chapel Hill, NC 27599-7361, USA.

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http://dx.doi.org/10.2217/pgs.13.88DOI Listing
July 2013

The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).

Pharmacogenet Genomics 2013 Jan;23(1):29-33

Sections of Clinical Pharmacology and Hematology/Oncology, Department of Medicine, The Geisel School of Medicine at Dartmouth, The Norris Cotton Cancer Center, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835b16d8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647228PMC
January 2013

Power and sample size calculations for SNP association studies with censored time-to-event outcomes.

Genet Epidemiol 2012 Sep 8;36(6):538-48. Epub 2012 Jun 8.

Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1002/gepi.21645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592339PMC
September 2012

A polymorphism within the promoter of the TGFβ1 gene is associated with radiation sensitivity using an objective radiologic endpoint.

Int J Radiat Oncol Biol Phys 2012 Feb 24;82(2):e247-55. Epub 2011 May 24.

Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2011.02.064DOI Listing
February 2012

SNPpy--database management for SNP data from genome wide association studies.

PLoS One 2011 19;6(10):e24982. Epub 2011 Oct 19.

Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024982PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198468PMC
February 2012

Statistical considerations for analysis of microarray experiments.

Clin Transl Sci 2011 Dec 7;4(6):466-77. Epub 2011 Nov 7.

Department of Biostatistics and Bioinformatics, Duke University CALGB Statistical Center, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2011.00309.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906917PMC
December 2011

"Sowing dragon's teeth?" Myeloma and AML.

Blood 2011 Oct;118(15):4008-9

Roswell Park Cancer Institute, USA.

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http://dx.doi.org/10.1182/blood-2011-08-372243DOI Listing
October 2011

Discriminating between latent and active tuberculosis with multiple biomarker responses.

Tuberculosis (Edinb) 2011 May 10;91(3):250-6. Epub 2011 Mar 10.

Center for AIDS Research, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.tube.2011.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090479PMC
May 2011

Multiple testing for gene sets from microarray experiments.

BMC Bioinformatics 2011 May 26;12:209. Epub 2011 May 26.

Biostatistics and Bioinformatics Center, Samsung Cancer Research Institute, Samsung Medical Center, Seoul 137-710, Republic of Korea.

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http://dx.doi.org/10.1186/1471-2105-12-209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131260PMC
May 2011

Robust test method for time-course microarray experiments.

BMC Bioinformatics 2010 Jul 22;11:391. Epub 2010 Jul 22.

Biostatistics and Bioinformatics Center, Samsung Cancer Research Institute, Samsung Medical Center, Seoul 137-710, Republic of Korea.

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http://dx.doi.org/10.1186/1471-2105-11-391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914731PMC
July 2010

permGPU: Using graphics processing units in RNA microarray association studies.

BMC Bioinformatics 2010 Jun 16;11:329. Epub 2010 Jun 16.

Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27705, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-11-329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910023PMC
June 2010

The importance of identifying and validating prognostic factors in oncology.

Semin Oncol 2010 Apr;37(2):e9-18

Department of Biostatistics and Bioinformatics and the Cancer and Leukemia Group B Statistical Center, Duke University Medical Center, Durham, NC 27705, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2010.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929829PMC
April 2010

A permutation-based multiple testing method for time-course microarray experiments.

BMC Bioinformatics 2009 Oct 15;10:336. Epub 2009 Oct 15.

Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1186/1471-2105-10-336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772858PMC
October 2009

Progression-free survival as a predictor of overall survival in men with castrate-resistant prostate cancer.

J Clin Oncol 2009 Jun 20;27(17):2766-71. Epub 2009 Apr 20.

Department of Biostatistics and Bioinformatics, Duke University Medical Center, 2424 Erwin Rd, Durham, NC 27705, USA.

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http://dx.doi.org/10.1200/JCO.2008.18.9159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698015PMC
June 2009

Designing phase II studies in cancer with time-to-event endpoints.

Clin Trials 2008 ;5(3):209-21

Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27705, USA.

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http://dx.doi.org/10.1177/1740774508091748DOI Listing
October 2008

Statistical challenges in preprocessing in microarray experiments in cancer.

Clin Cancer Res 2008 Oct;14(19):5959-66

Department of Biostatistics and Bioinformatics, and Cancer and Leukemia Group B Statistical Center, Duke University School of Medicine, 2424 Erwin Road, Durham, NC 27705, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-4532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529914PMC
October 2008

Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection.

Free Radic Biol Med 2008 Mar 21;44(6):982-9. Epub 2007 Nov 21.

Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2007.10.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684016PMC
March 2008

A copula approach for detecting prognostic genes associated with survival outcome in microarray studies.

Biometrics 2007 Dec 2;63(4):1089-98. Epub 2007 May 2.

Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina 27705, USA.

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http://dx.doi.org/10.1111/j.1541-0420.2007.00802.xDOI Listing
December 2007

P-value calculation for multistage phase II cancer clinical trials.

J Biopharm Stat 2006 ;16(6):765-75; discussion 777-83

Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1080/10543400600825645DOI Listing
January 2007

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis.

Carcinogenesis 2006 Apr 8;27(4):748-57. Epub 2005 Dec 8.

Department of Surgery and Division of Surgical Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/carcin/bgi292DOI Listing
April 2006

A multiple testing procedure to associate gene expression levels with survival.

Stat Med 2005 Oct;24(20):3077-88

Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27705, USA.

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http://dx.doi.org/10.1002/sim.2179DOI Listing
October 2005

Prophylactic thyroidectomy in multiple endocrine neoplasia type 2A.

N Engl J Med 2005 Sep;353(11):1105-13

Department of Surgery, Duke University School of Medicine, Durham, NC, USA.

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http://dx.doi.org/10.1056/NEJMoa043999DOI Listing
September 2005