Publications by authors named "Kouichi Ozaki"

60Publications

Identification of potential blood biomarkers for early diagnosis of Alzheimer's disease through RNA sequencing analysis.

Alzheimers Res Ther 2020 07 16;12(1):87. Epub 2020 Jul 16.

Medical Genome Center, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, 474-8511, Aichi, Japan.

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http://dx.doi.org/10.1186/s13195-020-00654-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367375PMC
July 2020

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.

Nat Genet 2020 07 8;52(7):669-679. Epub 2020 Jun 8.

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/s41588-020-0640-3DOI Listing
July 2020

A comparison of machine learning classifiers for dementia with Lewy bodies using miRNA expression data.

BMC Med Genomics 2019 10 30;12(1):150. Epub 2019 Oct 30.

Laboratory Chief, Division of Genomic Medicine, Medical Genome Center, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi, 474-8511, Japan.

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http://dx.doi.org/10.1186/s12920-019-0607-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822471PMC
October 2019

[Genetic Background for Alzheimer's Disease: Knowledge Accumulated from AD GWAS].

Brain Nerve 2019 Oct;71(10):1039-1051

Medical Genome Center, National Center for Geriatrics and Gerontology.

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http://dx.doi.org/10.11477/mf.1416201403DOI Listing
October 2019

Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway.

Int J Cardiol Heart Vasc 2019 Sep 4;24:100383. Epub 2019 Jul 4.

Department of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijcha.2019.100383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612921PMC
September 2019

Clinical utility and functional analysis of variants in atrial fibrillation-associated locus 4q25.

J Cardiol 2017 Oct 11;70(4):366-373. Epub 2017 Jan 11.

Department of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jjcc.2016.11.016DOI Listing
October 2017

[Molecular genetics of coronary artery diseases].

Nihon Rinsho 2016 Jun;74 Suppl 4 Pt 1:306-13

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June 2016

A functional SNP in FLT1 increases risk of coronary artery disease in a Japanese population.

J Hum Genet 2016 May 21;61(5):435-41. Epub 2016 Jan 21.

Laboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/jhg.2015.171DOI Listing
May 2016

Molecular genetics of coronary artery disease.

J Hum Genet 2016 Jan 2;61(1):71-7. Epub 2015 Jul 2.

Laboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/jhg.2015.70DOI Listing
January 2016

Exome Analyses of Long QT Syndrome Reveal Candidate Pathogenic Mutations in Calmodulin-Interacting Genes.

PLoS One 2015 1;10(7):e0130329. Epub 2015 Jul 1.

Laboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan; Department of Human Genetics and Disease Diversity, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130329PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488844PMC
April 2016

Induction of Systemic Resistance against Cucumber mosaic virus in Arabidopsis thaliana by Trichoderma asperellum SKT-1.

Plant Pathol J 2013 Jun;29(2):193-200

Laboratory of Plant Pathology, Faculty of Applied Biological Sciences, Gifu University, Gifu City 501-1193, Japan.

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http://dx.doi.org/10.5423/PPJ.SI.07.2012.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174775PMC
June 2013

[Genetic background of heart failure: SNP association study for heart failure and the underlying diseases].

Authors:
Kouichi Ozaki

Rinsho Byori 2013 Feb;61(2):167-75

Laboratory for Cardiovascular Diseases, RIKEN Center for Genomic Medicine, Yokohama 230-0045, Japan.

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February 2013

[The status for genetics of coronary artery disease].

Nihon Rinsho 2011 Nov;69 Suppl 9:217-21

Laboratory for Cardiovascular Diseases, Center for Genomic Medicine, RIKEN.

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November 2011

Meta-analysis identifies six new susceptibility loci for atrial fibrillation.

Nat Genet 2012 Apr 29;44(6):670-5. Epub 2012 Apr 29.

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366038PMC
April 2012

BRAP Activates Inflammatory Cascades and Increases the Risk for Carotid Atherosclerosis.

Mol Med 2011 Sep-Oct;17(9-10):1065-74. Epub 2011 Jun 10.

Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan Section of Neurology, Taichung Veterans General Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.2119/molmed.2011.00043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188876PMC
March 2012

Prediction model for knee osteoarthritis based on genetic and clinical information.

Arthritis Res Ther 2010 12;12(5):R187. Epub 2010 Oct 12.

Laboratory for Statistical Analysis, Center for Genomic Medicine, RIKEN, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1186/ar3157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991022PMC
March 2011

[Genetic background of acute coronary syndrome].

Authors:
Kouichi Ozaki

Nihon Rinsho 2010 Apr;68(4):615-20

Laboratory for Cardiovascular Diseases, Center for Genomic Medicine, Yokohama Institute, RIKEN.

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April 2010

Lymphotoxin-alpha3 mediates monocyte-endothelial interaction by TNFR I/NF-kappaB signaling.

Biochem Biophys Res Commun 2009 Feb 25;379(2):374-8. Epub 2008 Dec 25.

Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2008.12.064DOI Listing
February 2009

Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis.

Nat Genet 2008 Aug 11;40(8):994-8. Epub 2008 Jul 11.

Laboratory for Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1038/ng.176DOI Listing
August 2008

A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.

Hum Mol Genet 2008 Jun 6;17(12):1790-7. Epub 2008 Mar 6.

Laboratory for Bone and Joint Diseases, RIKEN SNP Research Center, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1093/hmg/ddn069DOI Listing
June 2008

A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction.

J Hum Genet 2007 9;52(3):220-229. Epub 2007 Jan 9.

Laboratory for Cardiovascular Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1007/s10038-006-0102-5DOI Listing
April 2007

Genome-wide association study to identify single-nucleotide polymorphisms conferring risk of myocardial infarction.

Methods Mol Med 2006 ;128:173-80

RIKEN, SNP Research Center, Tokyo, Japan.

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http://dx.doi.org/10.1007/978-1-59745-159-8_12DOI Listing
December 2006

Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.

J Hum Genet 2006 26;51(12):1087-1099. Epub 2006 Oct 26.

Laboratory for Cardiovascular Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1007/s10038-006-0070-9DOI Listing
February 2007

A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.

Nat Genet 2006 Aug 16;38(8):921-5. Epub 2006 Jul 16.

Laboratory for Cardiovascular Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://www.nature.com/articles/ng1846
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http://dx.doi.org/10.1038/ng1846DOI Listing
August 2006

Inflammation as a risk factor for myocardial infarction.

J Hum Genet 2006 13;51(7):595-604. Epub 2006 Jun 13.

Laboratory for Cardiovascular Diseases, Research Group for Disease-Causing Mechanisms, SNP Research Center, Riken, 4-6-1 Shirokanedai, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1007/s10038-006-0411-8DOI Listing
August 2006

Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene.

J Hum Genet 2005 10;50(1):42-45. Epub 2004 Dec 10.

Laboratory for Pharmacogenetics, Research Group of Personalized Medicine, RIKEN SNP Research Center, c/o RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi, Yokohama, Kanagawa, 230-0045, Japan.

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http://www.nature.com/doifinder/10.1007/s10038-004-0218-4
Publisher Site
http://dx.doi.org/10.1007/s10038-004-0218-4DOI Listing
March 2005

[Genome-wide SNP association study to identify genes related to myocardial infarction and their functional analyses].

Tanpakushitsu Kakusan Koso 2004 Nov;49(14):2215-21

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November 2004

Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.

Nature 2004 May;429(6987):72-5

Laboratory for Cardiovascular Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1038/nature02502DOI Listing
May 2004

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Authors:
Toshio Ota Yutaka Suzuki Tetsuo Nishikawa Tetsuji Otsuki Tomoyasu Sugiyama Ryotaro Irie Ai Wakamatsu Koji Hayashi Hiroyuki Sato Keiichi Nagai Kouichi Kimura Hiroshi Makita Mitsuo Sekine Masaya Obayashi Tatsunari Nishi Toshikazu Shibahara Toshihiro Tanaka Shizuko Ishii Jun-ichi Yamamoto Kaoru Saito Yuri Kawai Yuko Isono Yoshitaka Nakamura Kenji Nagahari Katsuhiko Murakami Tomohiro Yasuda Takao Iwayanagi Masako Wagatsuma Akiko Shiratori Hiroaki Sudo Takehiko Hosoiri Yoshiko Kaku Hiroyo Kodaira Hiroshi Kondo Masanori Sugawara Makiko Takahashi Katsuhiro Kanda Takahide Yokoi Takako Furuya Emiko Kikkawa Yuhi Omura Kumi Abe Kumiko Kamihara Naoko Katsuta Kazuomi Sato Machiko Tanikawa Makoto Yamazaki Ken Ninomiya Tadashi Ishibashi Hiromichi Yamashita Katsuji Murakawa Kiyoshi Fujimori Hiroyuki Tanai Manabu Kimata Motoji Watanabe Susumu Hiraoka Yoshiyuki Chiba Shinichi Ishida Yukio Ono Sumiyo Takiguchi Susumu Watanabe Makoto Yosida Tomoko Hotuta Junko Kusano Keiichi Kanehori Asako Takahashi-Fujii Hiroto Hara Tomo-o Tanase Yoshiko Nomura Sakae Togiya Fukuyo Komai Reiko Hara Kazuha Takeuchi Miho Arita Nobuyuki Imose Kaoru Musashino Hisatsugu Yuuki Atsushi Oshima Naokazu Sasaki Satoshi Aotsuka Yoko Yoshikawa Hiroshi Matsunawa Tatsuo Ichihara Namiko Shiohata Sanae Sano Shogo Moriya Hiroko Momiyama Noriko Satoh Sachiko Takami Yuko Terashima Osamu Suzuki Satoshi Nakagawa Akihiro Senoh Hiroshi Mizoguchi Yoshihiro Goto Fumio Shimizu Hirokazu Wakebe Haretsugu Hishigaki Takeshi Watanabe Akio Sugiyama Makoto Takemoto Bunsei Kawakami Masaaki Yamazaki Koji Watanabe Ayako Kumagai Shoko Itakura Yasuhito Fukuzumi Yoshifumi Fujimori Megumi Komiyama Hiroyuki Tashiro Akira Tanigami Tsutomu Fujiwara Toshihide Ono Katsue Yamada Yuka Fujii Kouichi Ozaki Maasa Hirao Yoshihiro Ohmori Ayako Kawabata Takeshi Hikiji Naoko Kobatake Hiromi Inagaki Yasuko Ikema Sachiko Okamoto Rie Okitani Takuma Kawakami Saori Noguchi Tomoko Itoh Keiko Shigeta Tadashi Senba Kyoka Matsumura Yoshie Nakajima Takae Mizuno Misato Morinaga Masahide Sasaki Takushi Togashi Masaaki Oyama Hiroko Hata Manabu Watanabe Takami Komatsu Junko Mizushima-Sugano Tadashi Satoh Yuko Shirai Yukiko Takahashi Kiyomi Nakagawa Koji Okumura Takahiro Nagase Nobuo Nomura Hisashi Kikuchi Yasuhiko Masuho Riu Yamashita Kenta Nakai Tetsushi Yada Yusuke Nakamura Osamu Ohara Takao Isogai Sumio Sugano

Nat Genet 2004 Jan 21;36(1):40-5. Epub 2003 Dec 21.

Helix Research Institute, 1532-3 Yana, Kisarazu, Chiba 292-0812, Japan.

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http://dx.doi.org/10.1038/ng1285DOI Listing
January 2004

Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21.

J Hum Genet 2003 13;48(9):476-479. Epub 2003 Aug 13.

Laboratory for Genotyping, RIKEN SNP Research Center, Kanagawa, Japan.

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http://dx.doi.org/10.1007/s10038-003-0054-yDOI Listing
December 2003

Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.

Nat Genet 2002 Dec 11;32(4):650-4. Epub 2002 Nov 11.

Laboratory for Cardiovascular Diseases, SNP Research Center, The Institute of Physical and Chemical Research (RIKEN), 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1038/ng1047DOI Listing
December 2002