Publications by authors named "Kostas Stamatopoulos"

100Publications

Exploiting B Cell Receptor Stereotypy to design Tailored Immunotherapy in Chronic Lymphocytic Leukemia.

Clin Cancer Res 2020 Oct 13. Epub 2020 Oct 13.

Division of Experimental Oncology, Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele.

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http://dx.doi.org/10.1158/1078-0432.CCR-20-1632DOI Listing
October 2020

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL.

Blood 2020 Sep 29. Epub 2020 Sep 29.

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.

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http://dx.doi.org/10.1182/blood.2020007039DOI Listing
September 2020

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus.

Leukemia 2020 09 9;34(9):2354-2363. Epub 2020 Jul 9.

Università Vita-Salute San Raffaele and IRCC Ospedale San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1038/s41375-020-0959-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347048PMC
September 2020

Development of a ePRO-Based Palliative Care Intervention for Cancer Patients: A Participatory Design Approach.

Stud Health Technol Inform 2020 Jun;270:941-945

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thermi, Thessaloniki, Greece.

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http://dx.doi.org/10.3233/SHTI200300DOI Listing
June 2020

Immunoglobulin heavy variable somatic hyper mutation status in chronic lymphocytic leukaemia: on the threshold of a new era?

Br J Haematol 2020 Jun 30;189(5):809-810. Epub 2020 Jan 30.

CERTH (Centre for Research & Technology - Hellas), Thessaloniki, Greece.

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http://dx.doi.org/10.1111/bjh.16480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318593PMC
June 2020

Study of gene expressions' correlation structures in subgroups of Chronic Lymphocytic Leukemia Patients.

J Biomed Inform 2019 07 18;95:103211. Epub 2019 May 18.

Department of Informatics, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.jbi.2019.103211DOI Listing
July 2019

Stereotyped B Cell Receptor Immunoglobulins in B Cell Lymphomas.

Methods Mol Biol 2019 ;1956:139-155

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.

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http://dx.doi.org/10.1007/978-1-4939-9151-8_7DOI Listing
July 2019

Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia.

Methods Mol Biol 2019 ;1881:51-62

Institute of Applied Biosciences, Center for Research and Technology, Thessaloniki, Greece.

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http://link.springer.com/10.1007/978-1-4939-8876-1_5
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http://dx.doi.org/10.1007/978-1-4939-8876-1_5DOI Listing
June 2019

IRProfiler - a software toolbox for high throughput immune receptor profiling.

BMC Bioinformatics 2018 04 18;19(1):144. Epub 2018 Apr 18.

Lab of Computing, Medical Informatics & Biomedical-Imaging Technologies, Department of Medicine, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.

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http://dx.doi.org/10.1186/s12859-018-2144-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907363PMC
April 2018

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations.

Haematologica 2018 05 15;103(5):865-873. Epub 2018 Feb 15.

Strategic Research Program on CLL and B-cell Neoplasia Unit, Division of Experimental Oncology, Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele, Milan, Italy

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http://dx.doi.org/10.3324/haematol.2017.177212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927998PMC
May 2018

T cells in chronic lymphocytic leukemia: can they fight?

Oncotarget 2017 Nov 3;8(59):99209-99210. Epub 2017 Nov 3.

Kostas Stamatopoulos: Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece and Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.18632/oncotarget.22277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725080PMC
November 2017

Chronic Lymphocytic Leukemia Patient Clustering Based on Somatic Hypermutation (SHM) Analysis.

Adv Exp Med Biol 2017;988:127-138

Centre for Research and Technology Hellas, Information Technologies Institute, Thessaloniki, 57001, Greece.

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http://dx.doi.org/10.1007/978-3-319-56246-9_10DOI Listing
May 2019

A gene is known by the company it keeps: enrichment of TNFAIP3 gene aberrations in MALT lymphomas expressing IGHV4-34 antigen receptors.

J Pathol 2017 12 1;243(4):403-406. Epub 2017 Nov 1.

Institute of Applied Biosciences, CERTH, The Centre for Research and Technology Hellas, Thessaloniki, Greece.

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http://dx.doi.org/10.1002/path.4982DOI Listing
December 2017

Monoclonal B-cell lymphocytosis in a hospital-based UK population and a rural Ugandan population: a cross-sectional study.

Lancet Haematol 2017 Jul;4(7):e334-e340

Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK; Medical Research Council/Uganda Virus Research Institute Uganda Research Unit on AIDS, Entebbe, Uganda. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(16)30192-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493519PMC
July 2017

Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia.

Nat Commun 2017 06 9;8:15746. Epub 2017 Jun 9.

Biocrystallography Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, via Olgettina 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1038/ncomms15746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472768PMC
June 2017

Cytotoxic T cells in chronic idiopathic neutropenia express restricted antigen receptors.

Leuk Lymphoma 2017 12 23;58(12):2926-2933. Epub 2017 May 23.

b Institute of Applied Biosciences, Center for Research and Technology , Thessaloniki , Greece.

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http://dx.doi.org/10.1080/10428194.2017.1324154DOI Listing
December 2017

Clonal B-cell lymphocytosis of marginal zone origin.

Best Pract Res Clin Haematol 2017 Mar - Jun;30(1-2):77-83. Epub 2016 Nov 4.

Institute of Applied Biosciences, CERTH, Thessaloniki, Greece; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2016.08.028DOI Listing
October 2017

B-cell malignancies: All roads lead to NF-κB activation.

Semin Cancer Biol 2016 08 18;39:1-2. Epub 2016 Aug 18.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Institute of Applied Biosciences, CERTH, Thessaloniki, Greece.

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http://dx.doi.org/10.1016/j.semcancer.2016.08.003DOI Listing
August 2016

NF-κB activation in chronic lymphocytic leukemia: A point of convergence of external triggers and intrinsic lesions.

Semin Cancer Biol 2016 08 1;39:40-8. Epub 2016 Aug 1.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2016.07.005DOI Listing
August 2016

Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies.

Semin Cancer Biol 2016 08 9;39:15-25. Epub 2016 Jul 9.

Division of Experimental Oncology, IRCCS San Raffaele Hospital, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2016.07.001DOI Listing
August 2016

B Cell Anergy Modulated by TLR1/2 and the miR-17∼92 Cluster Underlies the Indolent Clinical Course of Chronic Lymphocytic Leukemia Stereotyped Subset #4.

J Immunol 2016 05 8;196(10):4410-7. Epub 2016 Apr 8.

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki 57001, Greece; Hematology Department and Hematopoietic Cell Transplantation Unit, George Papanikolaou Hospital, Thessaloniki 57010, Greece; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala 75105, Sweden

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http://dx.doi.org/10.4049/jimmunol.1502297DOI Listing
May 2016

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

Haematologica 2016 Mar;101(3):263-5

Division of Experimental Oncology and Department of Onco-Hematology, Università Vita-Salute San Raffaele and IRCCS Instituto Scientifico San Raffaele, Milan, Italy

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http://dx.doi.org/10.3324/haematol.2015.139246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815716PMC
March 2016

Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia.

Clin Cancer Res 2016 Jan 2;22(1):167-74. Epub 2015 Sep 2.

Institute of Applied Biosciences, Center for Research and Technology Hellas, Thessaloniki, Greece. Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece. Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-3017DOI Listing
January 2016

Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8.

Blood 2015 Jun 21;125(23):3580-7. Epub 2015 Apr 21.

Division of Experimental Oncology, IRCCS Istituto Scientifico San Raffaele and Department of Onco-Hematology, Ospedale San Raffaele, Milan, Italy; Section of Internal Medicine, Università Vita-Salute San Raffaele, and.

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http://www.bloodjournal.org/content/125/23/3580.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-09-60
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http://dx.doi.org/10.1182/blood-2014-09-603217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458798PMC
June 2015

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.

Blood 2015 Jan 17;125(5):856-9. Epub 2014 Dec 17.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Institute of Applied Biosciences, Centre for Research and Technology-Hellas, Thessaloniki, Greece; Hematology Department and Hematopoietic Cell Transplantation Unit, Georgios Papanicolaou Hospital, Thessaloniki, Greece;

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http://www.bloodjournal.org/content/bloodjournal/125/5/856.f
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-09-60
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http://dx.doi.org/10.1182/blood-2014-09-600874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311230PMC
January 2015