Konstantinos Anastassiadis

Konstantinos Anastassiadis

UNVERIFIED PROFILE

Are you Konstantinos Anastassiadis?   Register this Author

Register author
Konstantinos Anastassiadis

Konstantinos Anastassiadis

Publications by authors named "Konstantinos Anastassiadis"

Are you Konstantinos Anastassiadis?   Register this Author

73Publications

1518Reads

26Profile Views

Prospective isolation of nonhematopoietic cells of the niche and their differential molecular interactions with HSCs.

Authors:
Nicole Mende Adrien Jolly Gulce I Percin Marko Günther Maria Rostovskaya Shyam M Krishnan Robert A J Oostendorp Andreas Dahl Konstantinos Anastassiadis Thomas Höfer Claudia Waskow

Blood 2019 10;134(15):1214-1226

Regeneration in Hematopoiesis and Animal Models in Hematopoiesis, Institute for Immunology Medical Faculty, Technische Universität (TU) Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1182/blood.2019000176DOI Listing
October 2019

Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.

Authors:
Ekaterina Mameishvili Ioannis Serafimidis Sara Iwaszkiewicz Mathias Lesche Susanne Reinhardt Nora Bölicke Maren Büttner Dimitris Stellas Adriana Papadimitropoulou Matthias Szabolcs Konstantinos Anastassiadis Andreas Dahl Fabian Theis Argiris Efstratiadis Anthony Gavalas

Proc Natl Acad Sci U S A 2019 10 23;116(41):20679-20688. Epub 2019 Sep 23.

Paul Langerhans Institute Dresden, Helmholtz Center Munich at the University Clinic Carl Gustav Carus of Technische Universität Dresden, German Research Center for Environmental Health, Helmholtz Zentrum München, D-85764 Neuherberg, Germany;

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1073/pnas.1901075116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789925PMC
October 2019

Inducible IL-7 Hyperexpression Influences Lymphocyte Homeostasis and Function and Increases Allograft Rejection.

Authors:
Maria Schreiber Marc Weigelt Anne Karasinsky Konstantinos Anastassiadis Sonja Schallenberg Cathleen Petzold Ezio Bonifacio Karsten Kretschmer Angela Hommel

Front Immunol 2019 10;10:742. Epub 2019 Apr 10.

Preclinical Approaches to Stem Cell Therapy/Diabetes, DFG-Center for Regenerative Therapies Dresden Cluster of Excellence, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.3389/fimmu.2019.00742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467976PMC
April 2019

Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.

Authors:
Yufei Chen Kenneth L Jones Konstantinos Anastassiadis Andrea Kranz A Francis Stewart Jolanta Grembecka Matthew Meyerson Patricia Ernst

Exp Hematol 2019 01 10;69:37-42. Epub 2018 Oct 10.

Department of Pediatrics, University of Colorado, Denver/Anschutz Medical Campus. Aurora, CO, USA; Department of Pharmacology, University of Colorado, Denver/Anschutz Medical Campus. Aurora, CO, USA. Electronic address:

View Article

Download full-text PDF

 Source
https://linkinghub.elsevier.com/retrieve/pii/S0301472X183085
Publisher Site
http://dx.doi.org/10.1016/j.exphem.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472707PMC
January 2019

Kmt2b conveys monovalent and bivalent H3K4me3 in mouse spermatogonial stem cells at germline and embryonic promoters.

Authors:
Shin-Ichi Tomizawa Yuki Kobayashi Takayuki Shirakawa Kumiko Watanabe Keita Mizoguchi Ikue Hoshi Kuniko Nakajima Jun Nakabayashi Sukhdeep Singh Andreas Dahl Dimitra Alexopoulou Masahide Seki Yutaka Suzuki Hélène Royo Antoine H F M Peters Konstantinos Anastassiadis A Francis Stewart Kazuyuki Ohbo

Development 2018 11 30;145(23). Epub 2018 Nov 30.

Department of Histology and Cell Biology, Yokohama City University School of Medicine, Yokohama 236-0004, Japan

View Article

Download full-text PDF

 Source
http://dev.biologists.org/lookup/doi/10.1242/dev.169102
Publisher Site
http://dx.doi.org/10.1242/dev.169102DOI Listing
November 2018

A single reporter mouse line for Vika, Flp, Dre, and Cre-recombination.

Authors:
Madina Karimova Oliver Baker Aylin Camgoz Ronald Naumann Frank Buchholz Konstantinos Anastassiadis

Sci Rep 2018 09 27;8(1):14453. Epub 2018 Sep 27.

Stem Cell Engineering, Biotechnology Center, Technische Universität Dresden, 01307, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://www.nature.com/articles/s41598-018-32802-7
Publisher Site
http://dx.doi.org/10.1038/s41598-018-32802-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160450PMC
September 2018

Human axial progenitors generate trunk neural crest cells in vitro.

Authors:
Thomas Jr Frith Ilaria Granata Matthew Wind Erin Stout Oliver Thompson Katrin Neumann Dylan Stavish Paul R Heath Daniel Ortmann James Os Hackland Konstantinos Anastassiadis Mina Gouti James Briscoe Valerie Wilson Stuart L Johnson Marysia Placzek Mario R Guarracino Peter W Andrews Anestis Tsakiridis

Elife 2018 08 10;7. Epub 2018 Aug 10.

Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, United Kingdom.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.7554/eLife.35786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101942PMC
August 2018

Inductive and Selective Effects of GSK3 and MEK Inhibition on Nanog Heterogeneity in Embryonic Stem Cells.

Authors:
Simon Hastreiter Stavroula Skylaki Dirk Loeffler Andreas Reimann Oliver Hilsenbeck Philipp S Hoppe Daniel L Coutu Konstantinos D Kokkaliaris Michael Schwarzfischer Konstantinos Anastassiadis Fabian J Theis Timm Schroeder

Stem Cell Reports 2018 07 17;11(1):58-69. Epub 2018 May 17.

Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland; Research Unit Stem Cell Dynamics, Helmholtz Zentrum München, 85764 Neuherberg, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.stemcr.2018.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066909PMC
July 2018

Clonal Analysis Delineates Transcriptional Programs of Osteogenic and Adipogenic Lineages of Adult Mouse Skeletal Progenitors.

Authors:
Maria Rostovskaya Samantha Donsante Benedetto Sacchetti Dimitra Alexopoulou Sylvia Klemroth Andreas Dahl Mara Riminucci Paolo Bianco Konstantinos Anastassiadis

Stem Cell Reports 2018 07 21;11(1):212-227. Epub 2018 Jun 21.

Stem Cell Engineering, BIOTEC, Technische Universität Dresden, 01307 Dresden, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.stemcr.2018.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067065PMC
July 2018

Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells.

Authors:
Thomas F Allison Andrew J H Smith Konstantinos Anastassiadis Jackie Sloane-Stanley Veronica Biga Dylan Stavish James Hackland Shan Sabri Justin Langerman Mark Jones Kathrin Plath Daniel Coca Ivana Barbaric Paul Gokhale Peter W Andrews

Stem Cell Reports 2018 06 17;10(6):1895-1907. Epub 2018 May 17.

Centre for Stem Cell Biology, Department of Biomedical Science, University of Sheffield, Sheffield S10 2TN, UK.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.stemcr.2018.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993559PMC
June 2018

The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.

Authors:
Kerstin Schmidt Qinyu Zhang Alpaslan Tasdogan Andreas Petzold Andreas Dahl Borros M Arneth Robert Slany Hans Jörg Fehling Andrea Kranz Adrian Francis Stewart Konstantinos Anastassiadis

Elife 2018 06 19;7. Epub 2018 Jun 19.

Stem Cell Engineering, Biotechnology Center, Technische Universität Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.7554/eLife.27157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025962PMC
June 2018

The Dox-pDC - A murine conditionally immortalized plasmacytoid dendritic cell line with native immune profile.

Authors:
Sebastian Thieme Alexander Holzbaur Ralf Wiedemuth Aline Binner Katrin Navratiel Konstantinos Anastassiadis Sebastian Brenner Cornelia Richter

PLoS One 2018 28;13(2):e0192437. Epub 2018 Feb 28.

Department of Pediatrics, University Clinic 'Carl Gustav Carus' Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192437PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830289PMC
April 2018

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes.

Authors:
Verena Schwach Arie O Verkerk Mervyn Mol Jantine J Monshouwer-Kloots Harsha D Devalla Valeria V Orlova Konstantinos Anastassiadis Christine L Mummery Richard P Davis Robert Passier

Stem Cell Reports 2017 12 22;9(6):1765-1779. Epub 2017 Nov 22.

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, the Netherlands; Department of Applied Stem Cell Technologies, MIRA Institute, University of Twente, Twente, the Netherlands. Electronic address:

View Article

Download full-text PDF

 Source
https://linkinghub.elsevier.com/retrieve/pii/S22136711173047
Publisher Site
http://dx.doi.org/10.1016/j.stemcr.2017.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785710PMC
December 2017

Single-cell mechanical phenotype is an intrinsic marker of reprogramming and differentiation along the mouse neural lineage.

Authors:
Marta Urbanska Maria Winzi Katrin Neumann Shada Abuhattum Philipp Rosendahl Paul Müller Anna Taubenberger Konstantinos Anastassiadis Jochen Guck

Development 2017 12;144(23):4313-4321

Cellular Machines, Biotechnology Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Tatzberg 47-49, Dresden 01307, Germany

View Article

Download full-text PDF

 Source
http://dev.biologists.org/lookup/doi/10.1242/dev.155218
Publisher Site
http://dx.doi.org/10.1242/dev.155218DOI Listing
December 2017

lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1.

Authors:
Debojyoti Chakraborty Maciej Paszkowski-Rogacz Nicolas Berger Li Ding Jovan Mircetic Jun Fu Vytautas Iesmantavicius Chunaram Choudhary Konstantinos Anastassiadis A Francis Stewart Frank Buchholz

Cell Rep 2017 Dec;21(11):3012-3021

Medical Systems Biology, UCC, Medical Faculty Carl Gustav Carus, TU Dresden, Fetscherstrasse 74, 01307 Dresden, Germany; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany; German Cancer Research Center (DKFZ), Heidelberg and German Cancer Consortium (DKTK) partner site Dresden, 01307 Dresden, Germany; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany. Electronic address:

View Article

Download full-text PDF

 Source
https://linkinghub.elsevier.com/retrieve/pii/S22111247173168
Publisher Site
http://dx.doi.org/10.1016/j.celrep.2017.11.045DOI Listing
December 2017

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.

Authors:
Maud Borensztein Ikuhiro Okamoto Laurène Syx Guillaume Guilbaud Christel Picard Katia Ancelin Rafael Galupa Patricia Diabangouaya Nicolas Servant Emmanuel Barillot Azim Surani Mitinori Saitou Chong-Jian Chen Konstantinos Anastassiadis Edith Heard

Nat Commun 2017 11 3;8(1):1297. Epub 2017 Nov 3.

Institut Curie, PSL Research University, CNRS UMR3215, INSERM U934, UPMC Paris-Sorbonne, 26 Rue d'Ulm, 75005, Paris, France.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/s41467-017-01415-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670228PMC
November 2017

Correction: TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes.

Authors:
Müge Akpınar Mathias Lesche Grigorios Fanourgakis Jun Fu Konstantinos Anastassiadis Andreas Dahl Rolf Jessberger

PLoS Genet 2017 Sep 1;13(9):e1006989. Epub 2017 Sep 1.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1371/journal.pgen.1006989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580917PMC
September 2017

The contribution of homology arms to nuclease-assisted genome engineering.

Authors:
Oliver Baker Sarah Tsurkan Jun Fu Barbara Klink Andreas Rump Mandy Obst Andrea Kranz Evelin Schröck Konstantinos Anastassiadis A Francis Stewart

Nucleic Acids Res 2017 Jul;45(13):8105-8115

Genomics, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1093/nar/gkx497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570031PMC
July 2017

, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.

Authors:
David Brici Qinyu Zhang Susanne Reinhardt Andreas Dahl Hella Hartmann Kerstin Schmidt Neha Goveas Jiahao Huang Lenka Gahurova Gavin Kelsey Konstantinos Anastassiadis A Francis Stewart Andrea Kranz

Development 2017 07 15;144(14):2606-2617. Epub 2017 Jun 15.

Genomics, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1242/dev.143347DOI Listing
July 2017

MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.

Authors:
Yufei Chen Konstantinos Anastassiadis Andrea Kranz A Francis Stewart Kathrin Arndt Claudia Waskow Akihiko Yokoyama Kenneth Jones Tobias Neff Yoo Lee Patricia Ernst

Cancer Cell 2017 06;31(6):755-770.e6

Department of Pediatrics, Section of Hematology/Oncology/BMT, University of Colorado, Denver/Anschutz Medical Campus, Aurora, CO 80045, USA; Department of Pharmacology, University of Colorado, Denver/Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.ccell.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598468PMC
June 2017

TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes.

Authors:
Müge Akpınar Mathias Lesche Grigorios Fanourgakis Jun Fu Konstantinos Anastassiadis Andreas Dahl Rolf Jessberger

PLoS Genet 2017 03 6;13(3):e1006660. Epub 2017 Mar 6.

Institute of Physiological Chemistry, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1371/journal.pgen.1006660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358835PMC
March 2017

RAC-tagging: Recombineering And Cas9-assisted targeting for protein tagging and conditional analyses.

Authors:
Oliver Baker Ashish Gupta Mandy Obst Youming Zhang Konstantinos Anastassiadis Jun Fu A Francis Stewart

Sci Rep 2016 05 24;6:25529. Epub 2016 May 24.

Genomics, Biotechnology Center, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/srep25529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877586PMC
May 2016

Functional Restoration of gp91phox-Oxidase Activity by BAC Transgenesis and Gene Targeting in X-linked Chronic Granulomatous Disease iPSCs.

Authors:
Magdalena Laugsch Maria Rostovskaya Sergiy Velychko Cornelia Richter Ariane Zimmer Barbara Klink Evelin Schröck Michael Haase Katrin Neumann Sebastian Thieme Joachim Roesler Sebastian Brenner Konstantinos Anastassiadis

Mol Ther 2016 Apr 28;24(4):812-22. Epub 2015 Aug 28.

Stem Cell Engineering, BIOTEC, TU Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/mt.2015.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886927PMC
April 2016

Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis.

Authors:
Manuela Völkner Marlen Zschätzsch Maria Rostovskaya Rupert W Overall Volker Busskamp Konstantinos Anastassiadis Mike O Karl

Stem Cell Reports 2016 Apr 31;6(4):525-538. Epub 2016 Mar 31.

German Center for Neurodegenerative Diseases (DZNE) Dresden, 01307 Dresden, Germany; CRTD - Center for Regenerative Therapies Dresden, Technische Universität Dresden, 01307 Dresden, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.stemcr.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834051PMC
April 2016

Thy-1/β3 Integrin Interaction-Induced Apoptosis of Dermal Fibroblasts Is Mediated by Up-Regulation of FasL Expression.

Authors:
Manuela Schmidt Danny Gutknecht Konstantinos Anastassiadis Beate Eckes Ulf Anderegg Anja Saalbach

J Invest Dermatol 2016 Feb 18;136(2):526-529. Epub 2015 Nov 18.

Department of Dermatology, Venereology and Allergology of Medical Faculty of Leipzig University, Leipzig, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.jid.2015.10.063DOI Listing
February 2016

Network plasticity of pluripotency transcription factors in embryonic stem cells.

Authors:
Adam Filipczyk Carsten Marr Simon Hastreiter Justin Feigelman Michael Schwarzfischer Philipp S Hoppe Dirk Loeffler Konstantinos D Kokkaliaris Max Endele Bernhard Schauberger Oliver Hilsenbeck Stavroula Skylaki Jan Hasenauer Konstantinos Anastassiadis Fabian J Theis Timm Schroeder

Nat Cell Biol 2015 Oct 21;17(10):1235-46. Epub 2015 Sep 21.

Research Unit Stem Cell Dynamics, Helmholtz Zentrum München-German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/ncb3237DOI Listing
October 2015

Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex.

Authors:
Fong Kuan Wong Ji-Feng Fei Felipe Mora-Bermúdez Elena Taverna Christiane Haffner Jun Fu Konstantinos Anastassiadis A Francis Stewart Wieland B Huttner

PLoS Biol 2015 Aug 7;13(8):e1002217. Epub 2015 Aug 7.

Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1371/journal.pbio.1002217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529158PMC
August 2015

Induction of potent CD8 T cell cytotoxicity by specific targeting of antigen to cross-presenting dendritic cells in vivo via murine or human XCR1.

Authors:
Evelyn Hartung Martina Becker Annabell Bachem Nele Reeg Anika Jäkel Andreas Hutloff Harald Weber Christoph Weise Claudia Giesecke Volker Henn Stephanie Gurka Konstantinos Anastassiadis Hans W Mages Richard A Kroczek

J Immunol 2015 Feb 17;194(3):1069-79. Epub 2014 Dec 17.

Molecular Immunology, Robert Koch-Institute, 13353 Berlin, Germany;

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.4049/jimmunol.1401903DOI Listing
February 2015

Breast carcinoma cells modulate the chemoattractive activity of human bone marrow-derived mesenchymal stromal cells by interfering with CXCL12.

Authors:
Manja Wobus Catrin List Tobias Dittrich Abhishek Dhawan Regina Duryagina Laleh S Arabanian Karin Kast Pauline Wimberger Maik Stiehler Lorenz C Hofbauer Franz Jakob Gerhard Ehninger Konstantinos Anastassiadis Martin Bornhäuser

Int J Cancer 2015 Jan 20;136(1):44-54. Epub 2014 May 20.

Division of Hematology, Oncology and Stem Cell Transplantation, Department of Medicine I, University Hospital Carl Gustav Carus, Technische Universiät Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1002/ijc.28960DOI Listing
January 2015

Cellular reporter systems for high-throughput screening of interactions between bioactive matrices and human mesenchymal stromal cells.

Authors:
Regina Duryagina Konstantinos Anastassiadis Manfred F Maitz Stefan Gramm Susan Schneider Manja Wobus Sebastian Thieme Sebastian Brenner Carsten Werner Martin Bornhäuser

Tissue Eng Part C Methods 2014 Oct 25;20(10):828-37. Epub 2014 Mar 25.

1 Medical Clinic and Policlinic I, University Hospital Dresden , Technische Universität, Dresden, Germany .

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1089/ten.TEC.2013.0590DOI Listing
October 2014

Nanog induces hyperplasia without initiating tumors.

Authors:
Gerrit Fischedick Guangming Wu Kenjiro Adachi Marcos J Araúzo-Bravo Boris Greber Martina Radstaak Gabriele Köhler Natalia Tapia Roberto Iacone Konstantinos Anastassiadis Hans R Schöler Holm Zaehres

Stem Cell Res 2014 Sep 10;13(2):300-15. Epub 2014 Aug 10.

Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Röntgenstrasse 20, 48149 Münster, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.scr.2014.08.001DOI Listing
September 2014

Gene targeting and site-specific recombination in mouse ES cells.

Authors:
Konstantinos Anastassiadis Frank Schnütgen Harald von Melchner A Francis Stewart

Methods Enzymol 2013 ;533:133-55

Center for Regenerative Therapies, Technische Universität Dresden, BioInnovationZentrum, Dresden, Germany. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/B978-0-12-420067-8.00009-XDOI Listing
August 2014

The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.

Authors:
Anita S Bledau Kerstin Schmidt Katrin Neumann Undine Hill Giovanni Ciotta Ashish Gupta Davi Coe Torres Jun Fu Andrea Kranz A Francis Stewart Konstantinos Anastassiadis

Development 2014 Mar;141(5):1022-35

Stem Cell Engineering, Technische Universität Dresden, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1242/dev.098152DOI Listing
March 2014

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.

Authors:
Sergei Denissov Helmut Hofemeister Hendrik Marks Andrea Kranz Giovanni Ciotta Sukhdeep Singh Konstantinos Anastassiadis Hendrik G Stunnenberg A Francis Stewart

Development 2014 Feb 14;141(3):526-37. Epub 2014 Jan 14.

Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences (NCMLS), Radboud University, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1242/dev.102681DOI Listing
February 2014

Generation of inducible immortalized dendritic cells with proper immune function in vitro and in vivo.

Authors:
Cornelia Richter Sebastian Thieme Joanna Bandoła Magdalena Laugsch Konstantinos Anastassiadis Sebastian Brenner

PLoS One 2013 23;8(4):e62621. Epub 2013 Apr 23.

Department of Pediatrics, University Clinic Carl Gustav Carus, Technische Universitaet Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062621PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633827PMC
November 2013

Age-dependent labeling and imaging of insulin secretory granules.

Authors:
Anna Ivanova Yannis Kalaidzidis Ronald Dirkx Mihail Sarov Michael Gerlach Britta Schroth-Diez Andreas Müller Yanmei Liu Cordula Andree Bernard Mulligan Carla Münster Thomas Kurth Marc Bickle Stephan Speier Konstantinos Anastassiadis Michele Solimena

Diabetes 2013 Nov 8;62(11):3687-96. Epub 2013 Aug 8.

Molecular Diabetology, Paul Langerhans Institute Dresden, Dresden University of Technology, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.2337/db12-1819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806613PMC
November 2013

Overexpression of Jagged-1 and its intracellular domain in human mesenchymal stromal cells differentially affect the interaction with hematopoietic stem and progenitor cells.

Authors:
Regina Duryagina Sebastian Thieme Konstantinos Anastassiadis Carsten Werner Susan Schneider Manja Wobus Sebastian Brenner Martin Bornhäuser

Stem Cells Dev 2013 Oct 24;22(20):2736-50. Epub 2013 Jul 24.

1 Medical Clinic and Policlinic I, University Hospital Carl Gustav Carus , Dresden, Germany .

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1089/scd.2012.0638DOI Listing
October 2013

Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments.

Authors:
Marina C Prewitz F Philipp Seib Malte von Bonin Jens Friedrichs Aline Stißel Christian Niehage Katrin Müller Konstantinos Anastassiadis Claudia Waskow Bernard Hoflack Martin Bornhäuser Carsten Werner

Nat Methods 2013 Aug 23;10(8):788-94. Epub 2013 Jun 23.

Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/nmeth.2523DOI Listing
August 2013

Biallelic expression of nanog protein in mouse embryonic stem cells.

Authors:
Adam Filipczyk Konstantinos Gkatzis Jun Fu Philipp S Hoppe Heiko Lickert Konstantinos Anastassiadis Timm Schroeder

Cell Stem Cell 2013 Jul;13(1):12-3

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.stem.2013.04.025DOI Listing
July 2013

Differential expression of surface markers in mouse bone marrow mesenchymal stromal cell subpopulations with distinct lineage commitment.

Authors:
Maria Rostovskaya Konstantinos Anastassiadis

PLoS One 2012 7;7(12):e51221. Epub 2012 Dec 7.

BIOTEC, Technische Universitaet Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051221PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517475PMC
June 2013

HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.

Authors:
Rashim Pal Singh Kristin Franke Joanna Kalucka Soulafa Mamlouk Antje Muschter Agnieszka Gembarska Tatyana Grinenko Carsten Willam Ronald Naumann Konstantinos Anastassiadis A Francis Stewart Stefan Bornstein Triantafyllos Chavakis Georg Breier Claudia Waskow Ben Wielockx

Blood 2013 Jun 10;121(26):5158-66. Epub 2013 May 10.

Emmy Noether Research Group, University of Technology, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1182/blood-2012-12-471185DOI Listing
June 2013

The histone demethylase UTX regulates stem cell migration and hematopoiesis.

Authors:
Sebastian Thieme Tobias Gyárfás Cornelia Richter Günes Özhan Jun Fu Dimitra Alexopoulou Michael H Muders Irene Michalk Christiane Jakob Andreas Dahl Barbara Klink Joanna Bandola Michael Bachmann Evelin Schröck Frank Buchholz A Francis Stewart Gilbert Weidinger Konstantinos Anastassiadis Sebastian Brenner

Blood 2013 Mar 30;121(13):2462-73. Epub 2013 Jan 30.

Department of Pediatrics, University Clinic Carl Gustav Carus Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1182/blood-2012-08-452003DOI Listing
March 2013

A localized Wnt signal orients asymmetric stem cell division in vitro.

Authors:
Shukry J Habib Bi-Chang Chen Feng-Chiao Tsai Konstantinos Anastassiadis Tobias Meyer Eric Betzig Roel Nusse

Science 2013 Mar;339(6126):1445-8

Department of Developmental Biology, Howard Hughes Medical Institute, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 265 Campus Drive, Stanford, CA 94305, USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1126/science.1231077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966430PMC
March 2013

Transposon mediated BAC transgenesis via pronuclear injection of mouse zygotes.

Authors:
Maria Rostovskaya Ronald Naumann Jun Fu Mandy Obst Doris Mueller A Francis Stewart Konstantinos Anastassiadis

Genesis 2013 Feb 25;51(2):135-41. Epub 2013 Jan 25.

Stem Cell Engineering, Biotechnology Center, Technische Universitaet Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1002/dvg.22362DOI Listing
February 2013

A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency.

Authors:
Diana Coronado Murielle Godet Pierre-Yves Bourillot Yann Tapponnier Agnieszka Bernat Maxime Petit Marielle Afanassieff Suzy Markossian Anna Malashicheva Roberto Iacone Konstantinos Anastassiadis Pierre Savatier

Stem Cell Res 2013 Jan 29;10(1):118-31. Epub 2012 Oct 29.

Stem Cell and Brain Research Institute, Bron, France.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.scr.2012.10.004DOI Listing
January 2013

Transposon-mediated BAC transgenesis in human ES cells.

Authors:
Maria Rostovskaya Jun Fu Mandy Obst Isabell Baer Stefanie Weidlich Hailong Wang Andrew J H Smith Konstantinos Anastassiadis A Francis Stewart

Nucleic Acids Res 2012 Oct 30;40(19):e150. Epub 2012 Jun 30.

Stem Cell Engineering, BioInnovationsZentrum, Technische Universitaet Dresden, Dresden 01307, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1093/nar/gks643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479164PMC
October 2012

The mammalian gene function resource: the International Knockout Mouse Consortium.

Authors:
Allan Bradley Konstantinos Anastassiadis Abdelkader Ayadi James F Battey Cindy Bell Marie-Christine Birling Joanna Bottomley Steve D Brown Antje Bürger Carol J Bult Wendy Bushell Francis S Collins Christian Desaintes Brendan Doe Aris Economides Janan T Eppig Richard H Finnell Colin Fletcher Martin Fray David Frendewey Roland H Friedel Frank G Grosveld Jens Hansen Yann Hérault Geoffrey Hicks Andreas Hörlein Richard Houghton Martin Hrabé de Angelis Danny Huylebroeck Vivek Iyer Pieter J de Jong James A Kadin Cornelia Kaloff Karen Kennedy Manousos Koutsourakis K C Kent Lloyd Susan Marschall Jeremy Mason Colin McKerlie Michael P McLeod Harald von Melchner Mark Moore Alejandro O Mujica Andras Nagy Mikhail Nefedov Lauryl M Nutter Guillaume Pavlovic Jane L Peterson Jonathan Pollock Ramiro Ramirez-Solis Derrick E Rancourt Marcello Raspa Jacques E Remacle Martin Ringwald Barry Rosen Nadia Rosenthal Janet Rossant Patricia Ruiz Noppinger Ed Ryder Joel Zupicich Schick Frank Schnütgen Paul Schofield Claudia Seisenberger Mohammed Selloum Elizabeth M Simpson William C Skarnes Damian Smedley William L Stanford A Francis Stewart Kevin Stone Kate Swan Hamsa Tadepally Lydia Teboul Glauco P Tocchini-Valentini David Valenzuela Anthony P West Ken-ichi Yamamura Yuko Yoshinaga Wolfgang Wurst

Mamm Genome 2012 Oct 12;23(9-10):580-6. Epub 2012 Sep 12.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1007/s00335-012-9422-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463800PMC
October 2012

Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms.

Authors:
Lukasz Wojtasz Jeffrey M Cloutier Marek Baumann Katrin Daniel János Varga Jun Fu Konstantinos Anastassiadis A Francis Stewart Attila Reményi James M A Turner Attila Tóth

Genes Dev 2012 May;26(9):958-73

Institute of Physiological Chemistry, Technische Universität Dresden, Dresden 01307, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1101/gad.187559.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347793PMC
May 2012

Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting.

Authors:
Marta Nedelkova Marcello Maresca Jun Fu Maria Rostovskaya Ramu Chenna Christian Thiede Konstantinos Anastassiadis Mihail Sarov A Francis Stewart

Nucleic Acids Res 2011 Nov 18;39(20):e137. Epub 2011 Aug 18.

Technische Universitaet Dresden, Genomics, BioInnovationsZentrum, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1093/nar/gkr668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203589PMC
November 2011

Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1.

Authors:
Katrin Daniel Julian Lange Khaled Hached Jun Fu Konstantinos Anastassiadis Ignasi Roig Howard J Cooke A Francis Stewart Katja Wassmann Maria Jasin Scott Keeney Attila Tóth

Nat Cell Biol 2011 May 10;13(5):599-610. Epub 2011 Apr 10.

Institute of Physiological Chemistry, Technische Universität Dresden, Fiedlerstrasse 42, 01307 Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/ncb2213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087846PMC
May 2011

Recombineering, transfection, Western, IP and ChIP methods for protein tagging via gene targeting or BAC transgenesis.

Authors:
Helmut Hofemeister Giovanni Ciotta Jun Fu Philipp Martin Seibert Alexander Schulz Marcello Maresca Mihail Sarov Konstantinos Anastassiadis A Francis Stewart

Methods 2011 Apr 31;53(4):437-52. Epub 2010 Dec 31.

Genomics, BioInnovationsZentrum, Technische Universitaet Dresden, Am Tatzberg 47, 01307 Dresden, Germany.

View Article

Download full-text PDF

 Source
http://linkinghub.elsevier.com/retrieve/pii/S104620231000309
Publisher Site
http://dx.doi.org/10.1016/j.ymeth.2010.12.026DOI Listing
April 2011

Recombineering BAC transgenes for protein tagging.

Authors:
Giovanni Ciotta Helmut Hofemeister Marcello Maresca Jun Fu Mihail Sarov Konstantinos Anastassiadis A Francis Stewart

Methods 2011 Feb 22;53(2):113-9. Epub 2010 Sep 22.

Genomics, BioInnovationsZentrum, Technische Universitaet Dresden, Am Tatzberg 47, 01307 Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.ymeth.2010.09.003DOI Listing
February 2011

PTBP1 is required for embryonic development before gastrulation.

Authors:
Jakob Suckale Olivia Wendling Jimmy Masjkur Melanie Jäger Carla Münster Konstantinos Anastassiadis A Francis Stewart Michele Solimena

PLoS One 2011 Feb 17;6(2):e16992. Epub 2011 Feb 17.

Molecular Diabetology, Paul Langerhans Institute Dresden, School of Medicine and University Clinic Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016992PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040740PMC
February 2011

A practical summary of site-specific recombination, conditional mutagenesis, and tamoxifen induction of CreERT2.

Authors:
Konstantinos Anastassiadis Stefan Glaser Andrea Kranz Kaj Berhardt A Francis Stewart

Methods Enzymol 2010 ;477:109-23

Center for Regenerative Therapy, Technische Universitaet Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
https://linkinghub.elsevier.com/retrieve/pii/S00766879107700
Publisher Site
http://dx.doi.org/10.1016/S0076-6879(10)77007-5DOI Listing
December 2010

A recombineering pipeline to make conditional targeting constructs.

Authors:
Jun Fu Madeleine Teucher Konstantinos Anastassiadis William Skarnes A Francis Stewart

Methods Enzymol 2010 ;477:125-44

Genomics, BioInnovationsZentrum, Technische Universitaet Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/S0076-6879(10)77008-7DOI Listing
December 2010

Dually inducible TetON systems for tissue-specific conditional gene expression in zebrafish.

Authors:
Franziska Knopf Kristin Schnabel Christa Haase Katja Pfeifer Konstantinos Anastassiadis Gilbert Weidinger

Proc Natl Acad Sci U S A 2010 Nov 1;107(46):19933-8. Epub 2010 Nov 1.

Biotechnology Center, Technische Universität Dresden, 01307 Dresden, Germany.

View Article

Download full-text PDF

 Source
http://www.pnas.org/cgi/doi/10.1073/pnas.1007799107
Publisher Site
http://dx.doi.org/10.1073/pnas.1007799107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993373PMC
November 2010

Tamoxifen-independent recombination in the RIP-CreER mouse.

Authors:
Yanmei Liu Jakob Suckale Jimmy Masjkur Maria Grazia Magro Anja Steffen Konstantinos Anastassiadis Michele Solimena

PLoS One 2010 Oct 22;5(10):e13533. Epub 2010 Oct 22.

Molecular Diabetology, Paul Langerhans Institute Dresden, School of Medicine and University Clinic Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013533PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965077PMC
October 2010

An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase.

Authors:
Andrea Kranz Jun Fu Kristin Duerschke Stefanie Weidlich Ronald Naumann A Francis Stewart Konstantinos Anastassiadis

Genesis 2010 Aug;48(8):512-20

Genomics, BioInnovationsZentrum, Technische Universität Dresden, Am Tatzberg 47, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1002/dvg.20641DOI Listing
August 2010

MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.

Authors:
Claudia V Andreu-Vieyra Ruihong Chen Julio E Agno Stefan Glaser Konstantinos Anastassiadis A Francis Stewart Martin M Matzuk

PLoS Biol 2010 Aug 17;8(8). Epub 2010 Aug 17.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1371/journal.pbio.1000453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923083PMC
August 2010

Precise conditional immortalization of mouse cells using tetracycline-regulated SV40 large T-antigen.

Authors:
Konstantinos Anastassiadis Maria Rostovskaya Sandra Lubitz Stefanie Weidlich A Francis Stewart

Genesis 2010 Apr;48(4):220-32

Center for Regenerative Therapies Dresden, BioInnovationsZentrum, Technische Universität Dresden, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1002/dvg.20605DOI Listing
April 2010

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice.

Authors:
Konstantinos Anastassiadis Jun Fu Christoph Patsch Shengbiao Hu Stefanie Weidlich Kristin Duerschke Frank Buchholz Frank Edenhofer A Francis Stewart

Dis Model Mech 2009 Sep-Oct;2(9-10):508-15. Epub 2009 Aug 19.

Center for Regenerative Therapies Dresden, BioInnovationsZentrum Technische Universitaet Dresden, Am Tatzberg 47, 01307 Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1242/dmm.003087DOI Listing
January 2010

The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.

Authors:
Herbert Schulz Raivo Kolde Priit Adler Irène Aksoy Konstantinos Anastassiadis Michael Bader Nathalie Billon Hélène Boeuf Pierre-Yves Bourillot Frank Buchholz Christian Dani Michael Xavier Doss Lesley Forrester Murielle Gitton Domingos Henrique Jürgen Hescheler Heinz Himmelbauer Norbert Hübner Efthimia Karantzali Androniki Kretsovali Sandra Lubitz Laurent Pradier Meena Rai Jüri Reimand Alexandra Rolletschek Agapios Sachinidis Pierre Savatier Francis Stewart Mike P Storm Marina Trouillas Jaak Vilo Melanie J Welham Johannes Winkler Anna M Wobus Antonis K Hatzopoulos

PLoS One 2009 Sep 3;4(9):e6804. Epub 2009 Sep 3.

Max-Delbrück-Center for Molecular Medicine Berlin-Buch, Berlin, Germany.

View Article

Download full-text PDF

 Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006804PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731164PMC
September 2009

Doxycycline-dependent photoactivated gene expression in eukaryotic systems.

Authors:
Sidney B Cambridge Daniel Geissler Federico Calegari Konstantinos Anastassiadis Mazahir T Hasan A Francis Stewart Wieland B Huttner Volker Hagen Tobias Bonhoeffer

Nat Methods 2009 Jul 7;6(7):527-31. Epub 2009 Jun 7.

Max Planck Institute of Neurobiology, Munich-Martinsried, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/nmeth.1340DOI Listing
July 2009

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.

Authors:
Li Ding Maciej Paszkowski-Rogacz Anja Nitzsche Mikolaj Michal Slabicki Anne-Kristin Heninger Ingrid de Vries Ralf Kittler Magno Junqueira Andrej Shevchenko Herbert Schulz Norbert Hubner Michael Xavier Doss Agapios Sachinidis Juergen Hescheler Roberto Iacone Konstantinos Anastassiadis A Francis Stewart M Teresa Pisabarro Antonio Caldarelli Ina Poser Mirko Theis Frank Buchholz

Cell Stem Cell 2009 May 2;4(5):403-15. Epub 2009 Apr 2.

Max-Planck-Institute for Molecular Cell Biology and Genetics, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.stem.2009.03.009DOI Listing
May 2009

The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis.

Authors:
Stefan Glaser Sandra Lubitz Kate L Loveland Kazu Ohbo Lorraine Robb Frieder Schwenk Jost Seibler Daniela Roellig Andrea Kranz Konstantinos Anastassiadis A Francis Stewart

Epigenetics Chromatin 2009 Apr 6;2(1). Epub 2009 Apr 6.

Genomics, BioInnovationsZentrum, Technische Universitaet Dresden, Am Tatzberg, 01307 Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1186/1756-8935-2-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674429PMC
April 2009

Bacterial artificial chromosome transgenesis through pronuclear injection of fertilized mouse oocytes.

Authors:
Kristina Vintersten Giuseppe Testa Ronald Naumann Konstantinos Anastassiadis A Francis Stewart

Methods Mol Biol 2008 ;415:83-100

Mount Sinai Hospital, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1007/978-1-59745-570-1_5DOI Listing
June 2008

Engineering embryonic stem cells with recombinase systems.

Authors:
Frank Schnütgen A Francis Stewart Harald von Melchner Konstantinos Anastassiadis

Methods Enzymol 2006 ;420:100-36

Department for Molecular Hematology, University of Frankfurt Medical School, Frankfurt am Main, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/S0076-6879(06)20007-7DOI Listing
August 2007

Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2.

Authors:
Sandra Lubitz Stefan Glaser Julia Schaft A Francis Stewart Konstantinos Anastassiadis

Mol Biol Cell 2007 Jun 11;18(6):2356-66. Epub 2007 Apr 11.

Genomics Group, BioInnovations Zentrum, Technische Universität Dresden, 01307 Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1091/mbc.e06-11-1060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1877088PMC
June 2007

Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development.

Authors:
Rüdiger J Blaschke Nathan D Hahurij Sanne Kuijper Steffen Just Lambertus J Wisse Kirsten Deissler Tina Maxelon Konstantinos Anastassiadis Jessica Spitzer Stefan E Hardt Hans Schöler Harma Feitsma Wolfgang Rottbauer Martin Blum Frits Meijlink Gudrun Rappold Adriana C Gittenberger-de Groot

Circulation 2007 Apr 19;115(14):1830-8. Epub 2007 Mar 19.

Human Genetics, University of Heidelberg, Heidelberg, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.106.637819DOI Listing
April 2007

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.

Authors:
Stefan Glaser Julia Schaft Sandra Lubitz Kristina Vintersten Frank van der Hoeven Katharina R Tufteland Rein Aasland Konstantinos Anastassiadis Siew-Lan Ang A Francis Stewart

Development 2006 Apr 15;133(8):1423-32. Epub 2006 Mar 15.

Genomics, BioInnovationsZentrum, Dresden University of Technology, Am Tatzberg 47, Dresden 01307, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1242/dev.02302DOI Listing
April 2006

Current issues in mouse genome engineering.

Authors:
Stefan Glaser Konstantinos Anastassiadis A Francis Stewart

Nat Genet 2005 Nov;37(11):1187-93

Genomics, BioInnovationsZentrum, Dresden University of Technology, Am Tatzberg 47, 01307, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://www.nature.com/articles/ng1668
Publisher Site
http://dx.doi.org/10.1038/ng1668DOI Listing
November 2005

A reliable lacZ expression reporter cassette for multipurpose, knockout-first alleles.

Authors:
Giuseppe Testa Julia Schaft Frank van der Hoeven Stefan Glaser Konstantinos Anastassiadis Youming Zhang Thomas Hermann Wolfgang Stremmel A Francis Stewart

Genesis 2004 Mar;38(3):151-8

Biotec, Technische Universität Dresden, c/o Max Planck Institute of Molecular cell Biology and Genetics, Dresden, Germany.

View Article

Download full-text PDF

 Source
http://doi.wiley.com/10.1002/gene.20012
Publisher Site
http://dx.doi.org/10.1002/gene.20012DOI Listing
March 2004

A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture.

Authors:
Konstantinos Anastassiadis Jinhyun Kim Nathalie Daigle Rolf Sprengel Hans R Schöler A Francis Stewart

Gene 2002 Oct;298(2):159-72

BIOTEC, TU Dresden, c/o Max-Planck-Institut für Molekulare Zellbiologie und Genetik MPI-CBG, Pfotenhauerstrasse 108, 01307 Dresden, Germany.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/s0378-1119(02)00979-4DOI Listing
October 2002