Publications by authors named "Konstantin H Dragnev"

52Publications

A Randomized Phase III Study of Abemaciclib Versus Erlotinib in Patients with Stage IV Non-small Cell Lung Cancer With a Detectable Mutation Who Failed Prior Platinum-Based Therapy: JUNIPER.

Authors:
Jonathan W Goldman Julien Mazieres Fabrice Barlesi Konstantin H Dragnev Marianna Koczywas Tuncay Göskel Alexis B Cortot Nicolas Girard Claas Wesseler Helge Bischoff Ernest Nadal Keunchil Park Shun Lu Alvaro Taus Manuel Cobo Shawn T Estrem Sameera R Wijayawardana Kellie Turner Gerard Joseph Oakley Karla C Hurt Alan Y Chiang Anwar M Hossain William J John Luis Paz-Ares

Front Oncol 2020 26;10:578756. Epub 2020 Oct 26.

Department of Medicine, Hospital Universitario 12 de Octubre, CNIO and Universidad Complutense, Madrid, Spain.

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October 2020

CDK4/6 inhibition enhances antitumor efficacy of chemotherapy and immune checkpoint inhibitor combinations in preclinical models and enhances T-cell activation in patients with SCLC receiving chemotherapy.

Authors:
Anne Y Lai Jessica A Sorrentino Konstantin H Dragnev Jared M Weiss Taofeek K Owonikoko Julie A Rytlewski Jill Hood Zhao Yang Rajesh K Malik Jay C Strum Patrick J Roberts

J Immunother Cancer 2020 Oct;8(2)

Research and Development, G1 Therapeutics, Inc, Research Triangle Park, North Carolina, USA.

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October 2020

Impact of neuroimaging in the pretreatment evaluation of early stage non-small cell lung cancer.

Authors:
Garrett T Wasp Christopher Del Prete Jonathan A D Farrell Konstantin H Dragnev Gregory Russo Graham T Atkins Joseph D Phillips Gabriel A Brooks

Heliyon 2020 Jun 29;6(6):e04319. Epub 2020 Jun 29.

Department of Internal Medicine, Section of Medical Oncology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr, Lebanon, NH, 03765, USA.

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June 2020

Molecular matching and treatment strategies for advanced stage lung cancer at Dartmouth-Hitchcock Medical Center: A three-year review of a Molecular Tumor Board.

Authors:
Erica B Bernhardt Mary D Chamberlin Ivan P Gorlov Francine B de Abreu Katarzyna J Bloch Jason D Peterson Gregory J Tsongalis Keisuke Shirai Konstantin H Dragnev Todd W Miller Laura J Tafe

Pract Lab Med 2020 Aug 12;21:e00174. Epub 2020 Jun 12.

Department of Pathology and Laboratory Medicine, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

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August 2020

Protein-altering germline mutations implicate novel genes related to lung cancer development.

Authors:
Xuemei Ji Semanti Mukherjee Maria Teresa Landi Yohan Bosse Philippe Joubert Dakai Zhu Ivan Gorlov Xiangjun Xiao Younghun Han Olga Gorlova Rayjean J Hung Yonathan Brhane Robert Carreras-Torres David C Christiani Neil Caporaso Mattias Johansson Geoffrey Liu Stig E Bojesen Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert Chu Chen Jinyoung Byun Konstantin H Dragnev John K Field Lambertus Fa Kiemeney Philip Lazarus Shan Zienolddiny Stephen Lam Matthew B Schabath Angeline S Andrew Pier A Bertazzi Angela C Pesatori Nancy Diao Li Su Lei Song Ruyang Zhang Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher Haiman Lynne Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Erik H F M van der Heijden Jin Hee Kim Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Gary E Goodman Angela Cox Fiona Taylor Penella Woll Erich Wichmann Thomas Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Lesley M Butler Kenneth Offit Preethi Srinivasan Chaitanya Bandlamudi Matthew D Hellmann David B Solit Mark E Robson Charles M Rudin Zsofia K Stadler Barry S Taylor Michael F Berger Richard Houlston John McLaughlin Victoria Stevens David C Nickle Ma'en Obeidat Wim Timens María Soler Artigas Sanjay Shete Hermann Brenner Stephen Chanock Paul Brennan James D McKay Christopher I Amos

Nat Commun 2020 05 11;11(1):2220. Epub 2020 May 11.

The Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, USA.

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May 2020

Rapid mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.

Authors:
M Rabie Al-Turkmani Michael A Suriawinata Sophie J Deharvengt Donald C Green Candice C Black Keisuke Shirai Konstantin H Dragnev Gregory J Tsongalis

Pract Lab Med 2020 May 2;20:e00156. Epub 2020 Mar 2.

Dartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.

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May 2020

An extended overall survival analysis of pemetrexed and carboplatin with or without pembrolizumab as first-line therapy for advanced non-squamous non-small cell lung cancer.

Authors:
Muhammad Zubair Afzal Konstantin H Dragnev Keisuke Shirai

Ann Transl Med 2019 Mar;7(Suppl 1):S53

Department of Hematology-Oncology, One Medical Center Dr., Lebanon, NH, USA.

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March 2019

Small-cell lung cancer growth inhibition: synergism between NMDA receptor blockade and chemotherapy.

Authors:
William G North Fuli Liu Konstantin H Dragnev Eugene Demidenko

Clin Pharmacol 2019 23;11:15-23. Epub 2019 Jan 23.

Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.

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January 2019

Hospitalization and Survival of Medicare Patients Treated With Carboplatin Plus Paclitaxel or Pemetrexed for Metastatic, Nonsquamous, Non-Small Cell Lung Cancer.

Authors:
Gabriel A Brooks Andrea M Austin Hajime Uno Konstantin H Dragnev Anna N A Tosteson Deborah Schrag

JAMA Netw Open 2018 10 5;1(6):e183023. Epub 2018 Oct 5.

Division of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.

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October 2018

A phase I/II study of bexarotene with carboplatin and weekly paclitaxel for the treatment of patients with advanced non-small cell lung cancer.

Authors:
Konstantin H Dragnev Jeremy D Whyman Cynthia K Hahn Peter E Kebbekus Sarah F Kokko Sunil M Bhatt James R Rigas

J Thorac Dis 2018 Sep;10(9):5531-5537

Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

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September 2018

The role of a palliative care intervention in moderating the relationship between depression and survival among individuals with advanced cancer.

Authors:
Anna T Prescott Jay G Hull J Nicholas Dionne-Odom Tor D Tosteson Kathleen Doyle Lyons Zhigang Li Zhongze Li Konstantin H Dragnev Mark T Hegel Karen E Steinhauser Tim A Ahles Marie A Bakitas

Health Psychol 2017 12 19;36(12):1140-1146. Epub 2017 Oct 19.

School of Nursing and Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham.

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December 2017

Clinical Genotyping of Non-Small Cell Lung Cancers Using Targeted Next-Generation Sequencing: Utility of Identifying Rare and Co-mutations in Oncogenic Driver Genes.

Authors:
Laura J Tafe Kirsten J Pierce Jason D Peterson Francine de Abreu Vincent A Memoli Candice C Black Jason R Pettus Jonathan D Marotti Edward J Gutmann Xiaoying Liu Keisuke Shirai Konstantin H Dragnev Christopher I Amos Gregory J Tsongalis

Neoplasia 2016 09;18(9):577-83

Department of Pathology and Laboratory Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH and Norris Cotton Cancer Center and Dartmouth-Hitchcock Medical Center, Lebanon, NH.

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September 2016

Family Caregiver Depressive Symptom and Grief Outcomes From the ENABLE III Randomized Controlled Trial.

Authors:
J Nicholas Dionne-Odom Andres Azuero Kathleen D Lyons Jay G Hull Anna T Prescott Tor Tosteson Jennifer Frost Konstantin H Dragnev Marie A Bakitas

J Pain Symptom Manage 2016 09 3;52(3):378-85. Epub 2016 Jun 3.

School of Nursing, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA; Division of Gerontology, Geriatrics, and Palliative Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. Electronic address:

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September 2016

The Pitfalls of Companion Diagnostics: Evaluation of Discordant EGFR Mutation Results from a Clinical Laboratory and a Central Laboratory.

Authors:
Scott A Turner Jason D Peterson Jason R Pettus Francine B de Abreu Christopher I Amos Konstantin H Dragnev Gregory J Tsongalis

J Mol Diagn 2016 05 7;18(3):331-335. Epub 2016 Mar 7.

Laboratory for Clinical Genomics and Advanced Technology, Department of Pathology, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire; Department of Pathology, Dartmouth-Hitchcock Medical Center and Norris Cotton Cancer Center, Lebanon, New Hampshire. Electronic address:

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May 2016

Reply to R.A. Ferrer et al and B.W. Corn.

Authors:
Marie Bakitas J Nicholas Dionne-Odom Kathleen Doyle Lyons Konstantin H Dragnev

J Clin Oncol 2015 Dec 12;33(35):4230-1. Epub 2015 Oct 12.

Dartmouth-Hitchcock Medical Center, Lebanon, NH.

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December 2015

Implementation of a Molecular Tumor Board: The Impact on Treatment Decisions for 35 Patients Evaluated at Dartmouth-Hitchcock Medical Center.

Authors:
Laura J Tafe Ivan P Gorlov Francine B de Abreu Joel A Lefferts Xiaoying Liu Jason R Pettus Jonathan D Marotti Kasia J Bloch Vincent A Memoli Arief A Suriawinata Konstantin H Dragnev Camilo E Fadul Gary N Schwartz Clinton R Morgan Britt M Holderness Jason D Peterson Gregory J Tsongalis Todd W Miller Mary D Chamberlin

Oncologist 2015 Sep 23;20(9):1011-8. Epub 2015 Jul 23.

Departments of Pathology, Community and Family Medicine, Medicine, and Pharmacology & Toxicology, Comprehensive Breast Program, and Familial Cancer Program, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA

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September 2015

Early Versus Delayed Initiation of Concurrent Palliative Oncology Care: Patient Outcomes in the ENABLE III Randomized Controlled Trial.

Authors:
Marie A Bakitas Tor D Tosteson Zhigang Li Kathleen D Lyons Jay G Hull Zhongze Li J Nicholas Dionne-Odom Jennifer Frost Konstantin H Dragnev Mark T Hegel Andres Azuero Tim A Ahles

J Clin Oncol 2015 May 23;33(13):1438-45. Epub 2015 Mar 23.

Marie A. Bakitas, J. Nicholas Dionne-Odom, and Andres Azuero, University of Alabama at Birmingham, Birmingham, AL; Marie A. Bakitas, Jennifer Frost, and Konstantin H. Dragnev, Dartmouth-Hitchcock Medical Center; Zhongze Li, Norris Cotton Cancer Center, Lebanon; Tor D. Tosteson, Kathleen D. Lyons, and Mark T. Hegel, Geisel School of Medicine at Dartmouth; Zhigang Li and Jay G. Hull, Dartmouth College, Hanover, NH; and Tim A. Ahles, Memorial Sloan-Kettering Cancer Center, New York, NY.

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May 2015

Benefits of Early Versus Delayed Palliative Care to Informal Family Caregivers of Patients With Advanced Cancer: Outcomes From the ENABLE III Randomized Controlled Trial.

Authors:
J Nicholas Dionne-Odom Andres Azuero Kathleen D Lyons Jay G Hull Tor Tosteson Zhigang Li Zhongze Li Jennifer Frost Konstantin H Dragnev Imatullah Akyar Mark T Hegel Marie A Bakitas

J Clin Oncol 2015 May 23;33(13):1446-52. Epub 2015 Mar 23.

J. Nicholas Dionne-Odom, Andres Azuero, Imatullah Akyar, and Marie A. Bakitas, University of Alabama at Birmingham, Birmingham, AL; Kathleen D. Lyons, Jay G. Hull, Zhigang Li, and Mark T. Hegel, Dartmouth College; Tor Tosteson and Zhongze Li, Norris Cotton Cancer Center, Hanover; and Jennifer Frost and Konstantin H. Dragnev, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

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May 2015

ALK-rearranged adenosquamous lung cancer presenting as squamous cell carcinoma: a potential challenge to histologic type triaging of NSCLC biopsies for molecular studies.

Authors:
Konstantin H Dragnev Gerald Gehr Vincent A Memoli Laura J Tafe

Clin Lung Cancer 2014 May 18;15(3):e37-40. Epub 2014 Jan 18.

Department of Pathology, Dartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center and The Geisel School of Medicine at Dartmouth, Lebanon, NH. Electronic address:

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May 2014

Epidermal growth factor receptor tyrosine kinase inhibitors as initial therapy for non-small cell lung cancer: focus on epidermal growth factor receptor mutation testing and mutation-positive patients.

Authors:
Monic Roengvoraphoj Gregory J Tsongalis Konstantin H Dragnev James R Rigas

Cancer Treat Rev 2013 Dec 12;39(8):839-50. Epub 2013 Jun 12.

Comprehensive Thoracic Oncology Program, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756-0001, USA; The Geisel School of Medicine at Dartmouth, One Rope Ferry Road, Hanover, NH 03755-1404, USA. Electronic address:

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December 2013