Konrad Bleicher

Konrad Bleicher

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Konrad Bleicher

Konrad Bleicher

Publications by authors named "Konrad Bleicher"

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Functionalized Proline-Rich Peptides Bind the Bacterial Second Messenger c-di-GMP.

Angew Chem Int Ed Engl 2018 06 23;57(26):7729-7733. Epub 2018 May 23.

Laboratorium für Organische Chemie, D-CHAB, ETH Zürich, Vladimir-Prelog-Weg 3, 8093, Zürich, Switzerland.

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http://dx.doi.org/10.1002/anie.201801845DOI Listing
June 2018

Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist.

Bioorg Med Chem Lett 2009 May 9;19(9):2595-8. Epub 2009 Mar 9.

Roche R&D Center(China) Ltd, 720 Cai Lun Road, Building 5, Pudong, Shanghai 201203, China.

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http://dx.doi.org/10.1016/j.bmcl.2009.03.008DOI Listing
May 2009

Ligand identification for G-protein-coupled receptors: a lead generation perspective.

Curr Opin Chem Biol 2004 Jun;8(3):287-96

F Hoffmann-La Roche Ltd, Pharmaceuticals Division, Lead Generation, PRBD-CI, Bldg 65/410, CH-4070 Basel, Switzerland.

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http://dx.doi.org/10.1016/j.cbpa.2004.04.008DOI Listing
June 2004

Hit and lead generation: beyond high-throughput screening.

Nat Rev Drug Discov 2003 May;2(5):369-78

F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, CH-4070, Basel, Switzerland.

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http://dx.doi.org/10.1038/nrd1086DOI Listing
May 2003

Chemogenomics: bridging a drug discovery gap.

Curr Med Chem 2002 Dec;9(23):2077-84

F. Hoffmann-La Roche Ltd., Pharmaceuticals Division, Discovery Chemistry, Basel, CH-4070, Switzerland.

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http://dx.doi.org/10.2174/0929867023368728DOI Listing
December 2002

Alkyl diphenylacetyl, 9H-xanthene- and 9H-thioxanthene-carbonyl carbamates as positive allosteric modulators of mGlu1 receptors.

Farmaco 2002 Dec;57(12):989-92

Pharmaceuticals Division, Preclinical CNS Research, F. Hoffmann-La Roche Ltd., Grenzachestr. 124, CH-4070 Basel, Switzerland.

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December 2002

Parallel solution- and solid-phase synthesis of spiropyrrolo-pyrroles as novel neurokinin receptor ligands.

Bioorg Med Chem Lett 2002 Nov;12(21):3073-6

F. Hoffmann-La Roche AG, Pharma Research, CH-4070, Basel, Switzerland.

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http://dx.doi.org/10.1016/s0960-894x(02)00659-5DOI Listing
November 2002

Parallel solution- and solid-phase synthesis of spirohydantoin derivatives as neurokinin-1 receptor ligands.

Bioorg Med Chem Lett 2002 Sep;12(18):2519-22

F. Hoffmann-La Roche AG, Pharma Research, CH-4070, Basel, Switzerland.

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http://dx.doi.org/10.1016/s0960-894x(02)00488-2DOI Listing
September 2002