Koichi Goto

Koichi Goto

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Koichi Goto

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Impressive response to nivolumab of non-small-cell lung cancer containing sarcomatoid components.

Respirol Case Rep 2019 Nov 20;7(8):e00477. Epub 2019 Aug 20.

Department of Thoracic Oncology National Cancer Center Hospital East Chiba Japan.

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http://dx.doi.org/10.1002/rcr2.477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702315PMC
November 2019

Validity of using immunohistochemistry to predict treatment outcome in patients with non-small cell lung cancer not otherwise specified.

J Cancer Res Clin Oncol 2019 Sep 7. Epub 2019 Sep 7.

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-019-03012-zDOI Listing
September 2019

Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts.

Pathol Int 2019 Aug 24;69(8):472-480. Epub 2019 Jul 24.

Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.

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http://dx.doi.org/10.1111/pin.12838DOI Listing
August 2019

Interaction between cancer cells and cancer-associated fibroblasts after cisplatin treatment promotes cancer cell regrowth.

Hum Cell 2019 Aug 22. Epub 2019 Aug 22.

Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1007/s13577-019-00275-zDOI Listing
August 2019

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.

Authors:
Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Ying Chen Kaiyun Yang Gening Jiang Ke Fei Guoping Wu Hsien-Chin Lin Hui-Ling Chen Yao-Huei Fang Fang-Yu Tsai Wan-Shan Hsieh Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Linda Rieswijk Ann Chao Pan-Chyr Yang Xiao-Ou Shu Tangchun Wu Y L Wu Dongxin Lin Kexin Chen Baosen Zhou Yun-Chao Huang Takashi Kohno Hongbing Shen Stephen J Chanock Nathaniel Rothman Qing Lan

Genomics 2019 Jul 12. Epub 2019 Jul 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ygeno.2019.07.008DOI Listing
July 2019

Utility of Site-Specific Biopsy for Diagnosis of Desmoplastic Malignant Mesothelioma.

Ann Thorac Surg 2018 09 28;106(3):e125-e128. Epub 2018 Mar 28.

Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.athoracsur.2018.02.062DOI Listing
September 2018

Reply to L. Zeng et al.

J Clin Oncol 2018 Sep 13:JCO1800584. Epub 2018 Sep 13.

Yi-Long Wu, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China; and Koichi Goto, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1200/JCO.18.00584DOI Listing
September 2018

Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells by mTOR activation through Akt-independent pathway.

Cancer Sci 2018 Jun;109(6):2063-2073

Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1111/cas.13624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989854PMC
June 2018

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma.

Cancer Res 2018 05 28;78(9):2179-2190. Epub 2018 Feb 28.

Division of Translational Genomics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-2109DOI Listing
May 2018

Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma.

J Cancer Res Clin Oncol 2018 May 6;144(5):893-900. Epub 2018 Mar 6.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-018-2619-3DOI Listing
May 2018

Phase II Study of Crizotinib in East Asian Patients With ROS1-Positive Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 05 29;36(14):1405-1411. Epub 2018 Mar 29.

Yi-Long Wu and Jin-Ji Yang, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou; Shun Lu, Jiao Tong University, Shanghai; Jianying Zhou, First Affiliated Hospital of Zhejiang University, Hangzhou, People's Republic of China; James Chih-Hsin Yang, National Taiwan University Hospital and National Taiwan University Cancer Center, Taipei, Republic of China; Dong-Wan Kim, Seoul National University Hospital; Myung-Ju Ahn, Samsung Medical Center, Seoul, South Korea; Takashi Seto, National Kyushu Cancer Center, Fukuoka; Noboru Yamamoto, National Cancer Center Hospital, Tokyo; Toshiaki Takahashi, Shizuoka Cancer Center, Shizuoka; Takeharu Yamanaka, Yokohama City University School of Medicine, Yokohama; Koichi Goto, National Cancer Center Hospital East, Kashiwa, Japan; Allison Kemner and Debasish Roychowdhury, OxOnc Development, Princeton, NJ; Nirvan Consultants, Lexington, MA; Jolanda Paolini and Tiziana Usari, Pfizer, Milan, Italy; and Keith D. Wilner, Pfizer, La Jolla, CA.

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http://dx.doi.org/10.1200/JCO.2017.75.5587DOI Listing
May 2018

Long-term results of S-1 plus cisplatin with concurrent thoracic radiotherapy for locally advanced non-small-cell lung cancer.

Cancer Chemother Pharmacol 2018 03 31;81(3):565-572. Epub 2018 Jan 31.

Department of Radiation Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1007/s00280-018-3530-yDOI Listing
March 2018

Immunohistochemical and genetic characteristics of lung cancer mimicking organizing pneumonia.

Lung Cancer 2017 11 5;113:134-139. Epub 2017 Oct 5.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.10.001DOI Listing
November 2017

Evaluation of drug-induced hematotoxicity using novel in vitro monkey CFU-GM and BFU-E colony assays.

J Toxicol Sci 2017 ;42(4):397-405

Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd.

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http://dx.doi.org/10.2131/jts.42.397DOI Listing
October 2017

[Current Status and Future Perspectives of SCRUM-Japan].

Gan To Kagaku Ryoho 2017 Aug;44(8):621-626

National Cancer Center Hospital East.

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August 2017

Impact of denosumab use on the survival of untreated non-squamous non-small cell lung cancer patients with bone metastases.

J Cancer Res Clin Oncol 2017 Jun 20;143(6):1075-1082. Epub 2017 Feb 20.

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-0882, Japan.

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http://link.springer.com/10.1007/s00432-017-2350-5
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http://dx.doi.org/10.1007/s00432-017-2350-5DOI Listing
June 2017

Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma.

Cancer Lett 2017 06 9;395:20-30. Epub 2017 Mar 9.

Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8561, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.02.026DOI Listing
June 2017

Switch maintenance chemotherapy using S-1 with or without bevacizumab in patients with advanced non-small cell lung cancer: a phase II study.

Lung Cancer 2017 06 1;108:66-71. Epub 2017 Mar 1.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2017.02.018DOI Listing
June 2017

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.

Authors:
Wei Jie Seow Keitaro Matsuo Chao Agnes Hsiung Kouya Shiraishi Minsun Song Hee Nam Kim Maria Pik Wong Yun-Chul Hong H Dean Hosgood Zhaoming Wang I-Shou Chang Jiu-Cun Wang Nilanjan Chatterjee Margaret Tucker Hu Wei Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Baosen Zhou Neil E Caporaso Demetrius Albanes Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Xiao-Ou Shu Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Michiaki Kubo Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Hiroshi Nokihara Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Zhihua Yin Jianxin Shi Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Tangchun Wu Fusheng Wei Jason Y Y Wong Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Victor Ho Fun Lee Wu-Chou Su Yuh-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Pan-Chyr Yang Hsien-Chih Lin Yong-Bing Xiang Adeline Seow Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Haixin Li Yu-Tang Gao Chen Wu Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Charles Lawrence Laurie Burdett Meredith Yeager Kevin B Jacobs Amy Hutchinson Sonja I Berndt Xingzhou He Wei Wu Junwen Wang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Alan Dart Loon Sihoe Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen John K C Chan Minjie Chu Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Yen-Li Lo Ying-Hsiang Chen Joseph F Fraumeni Jie Liu Taiki Yamaji Yang Yang Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Gening Jiang Ke Fei Guoping Wu Li-Hsin Chien Hui-Ling Chen Yu-Chun Su Fang-Yu Tsai Yi-Song Chen Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Dongxin Lin Kexin Chen Yi-Long Wu Maria Teresa Landi Hongbing Shen Nathaniel Rothman Takashi Kohno Stephen J Chanock Qing Lan

Hum Mol Genet 2017 01;26(2):454-465

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddw414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856088PMC
January 2017

Prognostic Factor Analysis in Patients With Small-Cell Lung Cancer Treated With Third-Line Chemotherapy.

Clin Lung Cancer 2016 11 16;17(6):581-587. Epub 2016 Jun 16.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.cllc.2016.05.022DOI Listing
November 2016

Clinical Impact of Gastric Acid-Suppressing Medication Use on the Efficacy of Erlotinib and Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer Harboring EGFR Mutations.

Clin Lung Cancer 2016 09 5;17(5):412-418. Epub 2016 Feb 5.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan; Juntendo University Graduate School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.cllc.2016.01.006DOI Listing
September 2016

Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced non-small cell lung cancer.

Jpn J Clin Oncol 2016 Aug 10. Epub 2016 Aug 10.

Division of Radiation Oncology and Particle Therapy, National Cancer Center Hospital East , Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1093/jjco/hyw108DOI Listing
August 2016

Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells.

PLoS One 2015 9;10(9):e0137595. Epub 2015 Sep 9.

Dept. of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA 90095, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137595PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564137PMC
May 2016

Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors.

Cancer Sci 2016 May 28;107(5):659-65. Epub 2016 Mar 28.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1111/cas.12912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970833PMC
May 2016

Factors influencing the concordance of histological subtype diagnosis from biopsy and resected specimens of lung adenocarcinoma.

Lung Cancer 2016 Apr 22;94:1-6. Epub 2016 Jan 22.

Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.01.009DOI Listing
April 2016

Unique intravascular tumor microenvironment predicting recurrence of lung squamous cell carcinoma.

J Cancer Res Clin Oncol 2016 Mar 31;142(3):593-600. Epub 2015 Oct 31.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-015-2068-1DOI Listing
March 2016

Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts.

J Cancer Res Clin Oncol 2016 Feb 15;142(2):437-46. Epub 2015 Sep 15.

Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://link.springer.com/content/pdf/10.1007%2Fs00432-015-20
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http://link.springer.com/10.1007/s00432-015-2046-7
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http://dx.doi.org/10.1007/s00432-015-2046-7DOI Listing
February 2016

A phase II study of pemetrexed plus carboplatin followed by maintenance pemetrexed as first-line chemotherapy for elderly patients with advanced non-squamous non-small cell lung cancer.

Med Oncol 2016 Jan 24;33(1). Epub 2015 Nov 24.

Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, 1180 Nakgasone-cho, Kita-ku, Sakai City, Osaka, 591-8555, Japan.

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http://dx.doi.org/10.1007/s12032-015-0715-7DOI Listing
January 2016

Phase I study of nintedanib in combination with pemetrexed as second-line treatment of Japanese patients with advanced non-small cell lung cancer.

Cancer Chemother Pharmacol 2015 Dec 11;76(6):1225-33. Epub 2015 Nov 11.

Department of Medical Oncology, Kinki University Faculty of Medicine, 377-2 Ohno-higashi, Osaka-Sayama, Osaka, 589-8511, Japan.

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http://dx.doi.org/10.1007/s00280-015-2896-3DOI Listing
December 2015

RECIST progression patterns during EGFR tyrosine kinase inhibitor treatment of advanced non-small cell lung cancer patients harboring an EGFR mutation.

Lung Cancer 2015 Dec 9;90(3):477-83. Epub 2015 Oct 9.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2015.09.025DOI Listing
December 2015

Phase II study of amrubicin at a dose of 45 mg/m2 in patients with previously treated small-cell lung cancer.

Jpn J Clin Oncol 2015 Oct 31;45(10):941-6. Epub 2015 Jul 31.

Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo.

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http://dx.doi.org/10.1093/jjco/hyv107DOI Listing
October 2015

Comparison of the expression levels of molecular markers among the peripheral area and central area of primary tumor and metastatic lymph node tumor in patients with squamous cell carcinoma of the lung.

J Cancer Res Clin Oncol 2015 Aug 9;141(8):1417-25. Epub 2015 Jan 9.

Pathology Division, Department of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, 277-8577, Japan.

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http://link.springer.com/10.1007/s00432-015-1912-7
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http://dx.doi.org/10.1007/s00432-015-1912-7DOI Listing
August 2015

Presence of podoplanin-positive cancer-associated fibroblasts in surgically resected primary lung adenocarcinoma predicts a shorter progression-free survival period in patients with recurrences who received platinum-based chemotherapy.

J Cancer Res Clin Oncol 2015 Jul 2;141(7):1163-70. Epub 2014 Dec 2.

Pathology Division, Department of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-014-1891-0DOI Listing
July 2015

Docetaxel for platinum-refractory advanced thymic carcinoma.

Jpn J Clin Oncol 2015 Jul 2;45(7):665-9. Epub 2015 Apr 2.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1093/jjco/hyv046DOI Listing
July 2015

Second-line docetaxel for patients with platinum-refractory advanced non-small cell lung cancer and interstitial pneumonia.

Cancer Chemother Pharmacol 2015 Jul 15;76(1):69-74. Epub 2015 May 15.

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://link.springer.com/10.1007/s00280-015-2775-y
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http://dx.doi.org/10.1007/s00280-015-2775-yDOI Listing
July 2015

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.

J Biol Chem 2015 Jul 28;290(28):17495-504. Epub 2015 May 28.

From the Division of Translational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba 277-8577, Japan, the Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba 277-8561.

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http://dx.doi.org/10.1074/jbc.M115.660498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498084PMC
July 2015

Genomic profiling of small-cell lung cancer: the era of targeted therapies.

Jpn J Clin Oncol 2015 Jun 10;45(6):513-9. Epub 2015 Feb 10.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa.

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https://academic.oup.com/jjco/article-lookup/doi/10.1093/jjc
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http://dx.doi.org/10.1093/jjco/hyv017DOI Listing
June 2015

Personality traits and coping styles explain anxiety in lung cancer patients to a greater extent than other factors.

Jpn J Clin Oncol 2015 May 10;45(5):456-63. Epub 2015 Mar 10.

Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

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http://dx.doi.org/10.1093/jjco/hyv024DOI Listing
May 2015

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer.

Transl Lung Cancer Res 2015 Apr;4(2):156-64

1 Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan ; 2 Division of Translational Research, Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo and Chiba, Japan ; 3 Division of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan ; 4 Division of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2014.11.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384213PMC
April 2015

Vinorelbine and cisplatin in patients with advanced non-small cell lung cancer with interstitial pneumonia.

Anticancer Res 2015 Mar;35(3):1697-701

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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March 2015

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis.

J Thorac Oncol 2014 Sep;9(9):1324-31

*Division of Thoracic Oncology, National Cancer Center Hospital East; †Exploratory Oncology Research and Clinical Trial Center, National Cancer Center; ‡Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East; §Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan; and ‖Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1097/JTO.0000000000000250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154841PMC
September 2014