Publications by authors named "Koichi Goto"

100Publications

Efficacy of Selpercatinib in Fusion-Positive Non-Small-Cell Lung Cancer.

N Engl J Med 2020 08;383(9):813-824

From Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College (A.D., E.R.) and New York University Langone Medical Center (V.V.), New York, and Roswell Park Comprehensive Cancer Center, Buffalo (G.K.D.) - all in New York; Dana-Farber Cancer Institute (G.R.O.) and Massachusetts General Hospital (J.G.), Boston; National Cancer Centre Singapore, Singapore (D.S.W.T.); the Chinese University of Hong Kong, Hong Kong, China (H.H.F.L.); Sarah Cannon Research Institute, Nashville (M.J.); University of California, San Francisco-Helen Diller Family Comprehensive Cancer Center, San Francisco (C.E.M.), University of California, San Diego, Moores Cancer Center, La Jolla (L.B.), and City of Hope Comprehensive Cancer Center, Duarte (K.L.R.) - all in California; University of Bern, Bern, and Cantonal Hospital of Lucerne, Lucerne - both in Switzerland (O.G.); Institut Gustave Roussy, Villejuif (B.B.), Hospital La Timone, Marseille (F.B.), and Centre Léon Bérard, Lyon (P.A.C.) - all in France; Severance Hospital, Yonsei University Health System (B.C.C.), and Samsung Medical Center, Sungkyunkwan University School of Medicine (K.P.), Seoul, and Seoul National University Bundang Hospital, Seongnam (Y.J.K.) - all in South Korea; Soroka University Medical Center, Beer-Sheva, Israel (N.P.); University of North Carolina-Chapel Hill, Chapel Hill (J. Weiss); National Cancer Center Hospital (Y.O.) and Cancer Institute Hospital of the Japanese Foundation for Cancer Research (M. Nishio), Tokyo, National Hospital Organization Kyushu Cancer Center, Fukuoka (T. Seto), Tottori University Hospital, Tottori (T. Sakamoto), Hyogo Cancer Center, Akashi (M.S.), Okayama University Hospital, Okayama (K.O.), and National Cancer Center Hospital East, Chiba (K.G.) - all in Japan; University of Chicago, Chicago (J.P.); the Ohio State University Comprehensive Cancer Center, Columbus (M.H.S.), and Cleveland Clinic, Cleveland (N.A.P.); Istituto Nazionale Tumori-National Cancer Institute, Università degli Studi di Milano, Milan (F.D.B.); Vall d'Hebron Institute of Oncology, Hospital Universitario Vall d'Hebron, Barcelona (E.G.); Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany (J. Wolf); Peter MacCallum Cancer Institute, Melbourne, VIC, Australia (B.S.); Sarah Cannon Research Institute at HealthONE, Denver (G.F.); Loxo Oncology, Stamford, CT (K.E., M. Nguyen, B.N., E.Y.Z., L.Y., X.H., E.O., S.M.R.); and the University of Texas M.D. Anderson Cancer Center, Houston (V.S.).

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http://dx.doi.org/10.1056/NEJMoa2005653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506467PMC
August 2020

Downregulation of CYLD promotes IFN-γ mediated PD-L1 expression in thymic epithelial tumors.

Lung Cancer 2020 Sep 22;147:221-228. Epub 2020 Jul 22.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA; Meyer Cancer Center, Weill Cornel Medicine, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.07.018DOI Listing
September 2020

MET amplification results in heterogeneous responses to osimertinib in EGFR-mutant lung cancer treated with erlotinib.

Cancer Sci 2020 Jul 31. Epub 2020 Jul 31.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1111/cas.14593DOI Listing
July 2020

Successful treatment of an osimertinib-resistant lung adenocarcinoma with an exon 18 EGFR mutation (G719S) with afatinib plus bevacizumab.

Invest New Drugs 2020 Jun 18. Epub 2020 Jun 18.

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka International Cancer Institute, Otemae 3-1-69, Chuo-ku, Osaka City, Osaka, 541-8567, Japan.

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http://dx.doi.org/10.1007/s10637-020-00966-7DOI Listing
June 2020

Comprehensive analysis of cardiac function, blood biomarkers and histopathology for milrinone-induced cardiotoxicity in cynomolgus monkeys.

J Pharmacol Toxicol Methods 2020 May - Jun;103:106870. Epub 2020 Apr 28.

Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13 Kita-Kasai, Edogawa-ku, Tokyo 134-8630, Japan.

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http://dx.doi.org/10.1016/j.vascn.2020.106870DOI Listing
April 2020

Uptake of collagen type I via macropinocytosis cause mTOR activation and anti-cancer drug resistance.

Biochem Biophys Res Commun 2020 May 20;526(1):191-198. Epub 2020 Mar 20.

Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.03.067DOI Listing
May 2020

Fluoroquinolones suppress gluconeogenesis by inhibiting fructose 1,6-bisphosphatase in primary monkey hepatocytes.

Toxicol In Vitro 2020 Jun 29;65:104786. Epub 2020 Jan 29.

Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13 Kita-Kasai, Edogawa-ku, Tokyo 134-8630, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2020.104786DOI Listing
June 2020

Validity of using immunohistochemistry to predict treatment outcome in patients with non-small cell lung cancer not otherwise specified.

J Cancer Res Clin Oncol 2019 Oct 7;145(10):2495-2506. Epub 2019 Sep 7.

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-019-03012-zDOI Listing
October 2019

Impressive response to nivolumab of non-small-cell lung cancer containing sarcomatoid components.

Respirol Case Rep 2019 Nov 20;7(8):e00477. Epub 2019 Aug 20.

Department of Thoracic Oncology National Cancer Center Hospital East Chiba Japan.

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http://dx.doi.org/10.1002/rcr2.477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702315PMC
November 2019

Interaction between cancer cells and cancer-associated fibroblasts after cisplatin treatment promotes cancer cell regrowth.

Hum Cell 2019 Oct 22;32(4):453-464. Epub 2019 Aug 22.

Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1007/s13577-019-00275-zDOI Listing
October 2019

Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts.

Pathol Int 2019 Aug 24;69(8):472-480. Epub 2019 Jul 24.

Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.

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http://dx.doi.org/10.1111/pin.12838DOI Listing
August 2019

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.

Authors:
Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Ying Chen Kaiyun Yang Gening Jiang Ke Fei Guoping Wu Hsien-Chin Lin Hui-Ling Chen Yao-Huei Fang Fang-Yu Tsai Wan-Shan Hsieh Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Linda Rieswijk Ann Chao Pan-Chyr Yang Xiao-Ou Shu Tangchun Wu Y L Wu Dongxin Lin Kexin Chen Baosen Zhou Yun-Chao Huang Takashi Kohno Hongbing Shen Stephen J Chanock Nathaniel Rothman Qing Lan

Genomics 2020 03 12;112(2):1223-1232. Epub 2019 Jul 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ygeno.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954985PMC
March 2020

Reply to L. Zeng et al.

J Clin Oncol 2018 Sep 13:JCO1800584. Epub 2018 Sep 13.

Yi-Long Wu, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China; and Koichi Goto, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1200/JCO.18.00584DOI Listing
September 2018

Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells by mTOR activation through Akt-independent pathway.

Cancer Sci 2018 Jun;109(6):2063-2073

Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1111/cas.13624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989854PMC
June 2018

Utility of Site-Specific Biopsy for Diagnosis of Desmoplastic Malignant Mesothelioma.

Ann Thorac Surg 2018 09 28;106(3):e125-e128. Epub 2018 Mar 28.

Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.athoracsur.2018.02.062DOI Listing
September 2018

Phase II Study of Crizotinib in East Asian Patients With ROS1-Positive Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 05 29;36(14):1405-1411. Epub 2018 Mar 29.

Yi-Long Wu and Jin-Ji Yang, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou; Shun Lu, Jiao Tong University, Shanghai; Jianying Zhou, First Affiliated Hospital of Zhejiang University, Hangzhou, People's Republic of China; James Chih-Hsin Yang, National Taiwan University Hospital and National Taiwan University Cancer Center, Taipei, Republic of China; Dong-Wan Kim, Seoul National University Hospital; Myung-Ju Ahn, Samsung Medical Center, Seoul, South Korea; Takashi Seto, National Kyushu Cancer Center, Fukuoka; Noboru Yamamoto, National Cancer Center Hospital, Tokyo; Toshiaki Takahashi, Shizuoka Cancer Center, Shizuoka; Takeharu Yamanaka, Yokohama City University School of Medicine, Yokohama; Koichi Goto, National Cancer Center Hospital East, Kashiwa, Japan; Allison Kemner and Debasish Roychowdhury, OxOnc Development, Princeton, NJ; Nirvan Consultants, Lexington, MA; Jolanda Paolini and Tiziana Usari, Pfizer, Milan, Italy; and Keith D. Wilner, Pfizer, La Jolla, CA.

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http://dx.doi.org/10.1200/JCO.2017.75.5587DOI Listing
May 2018

Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma.

J Cancer Res Clin Oncol 2018 May 6;144(5):893-900. Epub 2018 Mar 6.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-018-2619-3DOI Listing
May 2018

Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma.

Cancer Res 2018 05 28;78(9):2179-2190. Epub 2018 Feb 28.

Division of Translational Genomics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-2109DOI Listing
May 2018

Long-term results of S-1 plus cisplatin with concurrent thoracic radiotherapy for locally advanced non-small-cell lung cancer.

Cancer Chemother Pharmacol 2018 03 31;81(3):565-572. Epub 2018 Jan 31.

Department of Radiation Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1007/s00280-018-3530-yDOI Listing
March 2018

Immunohistochemical and genetic characteristics of lung cancer mimicking organizing pneumonia.

Lung Cancer 2017 11 5;113:134-139. Epub 2017 Oct 5.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.10.001DOI Listing
November 2017

[Current Status and Future Perspectives of SCRUM-Japan].

Gan To Kagaku Ryoho 2017 Aug;44(8):621-626

National Cancer Center Hospital East.

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August 2017

Evaluation of drug-induced hematotoxicity using novel in vitro monkey CFU-GM and BFU-E colony assays.

J Toxicol Sci 2017 ;42(4):397-405

Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd.

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http://dx.doi.org/10.2131/jts.42.397DOI Listing
October 2017

Switch maintenance chemotherapy using S-1 with or without bevacizumab in patients with advanced non-small cell lung cancer: a phase II study.

Lung Cancer 2017 06 1;108:66-71. Epub 2017 Mar 1.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2017.02.018DOI Listing
June 2017

Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma.

Cancer Lett 2017 06 9;395:20-30. Epub 2017 Mar 9.

Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8561, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.02.026DOI Listing
June 2017

Impact of denosumab use on the survival of untreated non-squamous non-small cell lung cancer patients with bone metastases.

J Cancer Res Clin Oncol 2017 Jun 20;143(6):1075-1082. Epub 2017 Feb 20.

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-0882, Japan.

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http://link.springer.com/10.1007/s00432-017-2350-5
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http://dx.doi.org/10.1007/s00432-017-2350-5DOI Listing
June 2017

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.

Authors:
Wei Jie Seow Keitaro Matsuo Chao Agnes Hsiung Kouya Shiraishi Minsun Song Hee Nam Kim Maria Pik Wong Yun-Chul Hong H Dean Hosgood Zhaoming Wang I-Shou Chang Jiu-Cun Wang Nilanjan Chatterjee Margaret Tucker Hu Wei Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Baosen Zhou Neil E Caporaso Demetrius Albanes Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Xiao-Ou Shu Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Michiaki Kubo Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Hiroshi Nokihara Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Zhihua Yin Jianxin Shi Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Tangchun Wu Fusheng Wei Jason Y Y Wong Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Victor Ho Fun Lee Wu-Chou Su Yuh-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Pan-Chyr Yang Hsien-Chih Lin Yong-Bing Xiang Adeline Seow Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Haixin Li Yu-Tang Gao Chen Wu Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Charles Lawrence Laurie Burdett Meredith Yeager Kevin B Jacobs Amy Hutchinson Sonja I Berndt Xingzhou He Wei Wu Junwen Wang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Alan Dart Loon Sihoe Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen John K C Chan Minjie Chu Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Yen-Li Lo Ying-Hsiang Chen Joseph F Fraumeni Jie Liu Taiki Yamaji Yang Yang Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Gening Jiang Ke Fei Guoping Wu Li-Hsin Chien Hui-Ling Chen Yu-Chun Su Fang-Yu Tsai Yi-Song Chen Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Dongxin Lin Kexin Chen Yi-Long Wu Maria Teresa Landi Hongbing Shen Nathaniel Rothman Takashi Kohno Stephen J Chanock Qing Lan

Hum Mol Genet 2017 01;26(2):454-465

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddw414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856088PMC
January 2017

Prognostic Factor Analysis in Patients With Small-Cell Lung Cancer Treated With Third-Line Chemotherapy.

Clin Lung Cancer 2016 11 16;17(6):581-587. Epub 2016 Jun 16.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.cllc.2016.05.022DOI Listing
November 2016

Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced non-small cell lung cancer.

Jpn J Clin Oncol 2016 Nov;46(11):1008-1014

Division of Radiation Oncology and Particle Therapy, National Cancer Center Hospital East , Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1093/jjco/hyw108DOI Listing
November 2016

Factors influencing the concordance of histological subtype diagnosis from biopsy and resected specimens of lung adenocarcinoma.

Lung Cancer 2016 Apr 22;94:1-6. Epub 2016 Jan 22.

Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.01.009DOI Listing
April 2016

Clinical Impact of Gastric Acid-Suppressing Medication Use on the Efficacy of Erlotinib and Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer Harboring EGFR Mutations.

Clin Lung Cancer 2016 09 5;17(5):412-418. Epub 2016 Feb 5.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan; Juntendo University Graduate School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.cllc.2016.01.006DOI Listing
September 2016

Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors.

Cancer Sci 2016 May 28;107(5):659-65. Epub 2016 Mar 28.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1111/cas.12912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970833PMC
May 2016

RECIST progression patterns during EGFR tyrosine kinase inhibitor treatment of advanced non-small cell lung cancer patients harboring an EGFR mutation.

Lung Cancer 2015 Dec 9;90(3):477-83. Epub 2015 Oct 9.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2015.09.025DOI Listing
December 2015

A phase II study of pemetrexed plus carboplatin followed by maintenance pemetrexed as first-line chemotherapy for elderly patients with advanced non-squamous non-small cell lung cancer.

Med Oncol 2016 Jan 24;33(1). Epub 2015 Nov 24.

Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, 1180 Nakgasone-cho, Kita-ku, Sakai City, Osaka, 591-8555, Japan.

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http://dx.doi.org/10.1007/s12032-015-0715-7DOI Listing
January 2016

Phase I study of nintedanib in combination with pemetrexed as second-line treatment of Japanese patients with advanced non-small cell lung cancer.

Cancer Chemother Pharmacol 2015 Dec 11;76(6):1225-33. Epub 2015 Nov 11.

Department of Medical Oncology, Kinki University Faculty of Medicine, 377-2 Ohno-higashi, Osaka-Sayama, Osaka, 589-8511, Japan.

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http://dx.doi.org/10.1007/s00280-015-2896-3DOI Listing
December 2015