Kohichi Kawahara

Kohichi Kawahara

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Kohichi Kawahara

Kohichi Kawahara

Publications by authors named "Kohichi Kawahara"

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Structural requirements of cholenamide derivatives as the LXR ligands.

Bioorg Med Chem Lett 2019 Jun 30;29(11):1330-1335. Epub 2019 Mar 30.

Department of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Akiha-ku, Niigata 956-8603, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.03.051DOI Listing
June 2019

FEAT enhances INSL3 expression in testicular Leydig cells.

Genes Cells 2018 Nov 2;23(11):952-962. Epub 2018 Oct 2.

Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1111/gtc.12644DOI Listing
November 2018

Thymidine phosphorylase in cancer aggressiveness and chemoresistance.

Pharmacol Res 2018 06 28;132:15-20. Epub 2018 Mar 28.

Clinical Research Center, National Kyushu Cancer Center, 3-1-1 Notame Minami-ku, Fukuoka 811-1395, Japan.

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http://dx.doi.org/10.1016/j.phrs.2018.03.019DOI Listing
June 2018

A novel isolation method for cancer prognostic factors via the p53 pathway by a combination of and analyses.

Oncoscience 2018 Mar 29;5(3-4):88-98. Epub 2018 Apr 29.

Department of Molecular Oncology, Graduate School Medical and Dental Sciences, Kagoshima University, Kagoshima 890- 8544, Japan.

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http://dx.doi.org/10.18632/oncoscience.411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978436PMC
March 2018

Plexin A1 signaling confers malignant phenotypes in lung cancer cells.

Biochem Biophys Res Commun 2016 Nov 4;480(1):75-80. Epub 2016 Oct 4.

Department of Pharmacology, Faculty of Pharmacy, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Akiha-ku, Niigata, Niigata 956-8603, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.10.006DOI Listing
November 2016

Autocrine Semaphorin3A signaling is essential for the maintenance of stem-like cells in lung cancer.

Biochem Biophys Res Commun 2016 Nov 19;480(3):375-379. Epub 2016 Oct 19.

Department of Pharmacology, Faculty of Pharmacy, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Akiha-ku, Niigata-city, Niigata 956-8603, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.10.057DOI Listing
November 2016

Cancer pain relief achieved by disrupting tumor-driven semaphorin 3A signaling in mice.

Neurosci Lett 2016 Oct 1;632:147-51. Epub 2016 Sep 1.

Department of Pharmacology, Faculty of Pharmacy, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Akiha-ku, Niigata-shi, Niigata-ken 956-8603, Japan.

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http://dx.doi.org/10.1016/j.neulet.2016.08.060DOI Listing
October 2016

mTORC1 is a critical mediator of oncogenic Semaphorin3A signaling.

Biochem Biophys Res Commun 2016 08 28;476(4):475-480. Epub 2016 May 28.

Department of Pharmacology, Faculty of Pharmacy, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Akiha-ku, Niigata-shi, Niigata-ken 956-8603, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.05.147DOI Listing
August 2016

Tumor cell-derived secretory factor downregulates Semaphorin-3a in osteoblasts by activating mammalian target of rapamycin pathway.

Biosci Biotechnol Biochem 2016 May 11;80(5):942-4. Epub 2016 Feb 11.

a Faculty of Pharmacy, Department of Pharmacology , Niigata University of Pharmacy and Applied Life Sciences , Niigata , Japan.

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http://dx.doi.org/10.1080/09168451.2015.1136881DOI Listing
May 2016

Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium.

Proc Natl Acad Sci U S A 2015 Aug 20;112(31):E4264-71. Epub 2015 Jul 20.

Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan; Laboratory of Biosignal Sciences, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan;

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http://dx.doi.org/10.1073/pnas.1510167112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534239PMC
August 2015

Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors.

Biochim Biophys Acta 2015 Apr 17;1851(4):414-21. Epub 2014 Jul 17.

Department of Pharmaceutical Biochemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Saitama 332-0012, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13881981140014
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http://dx.doi.org/10.1016/j.bbalip.2014.07.008DOI Listing
April 2015

Inhibition of PTEN tumor suppressor promotes the generation of induced pluripotent stem cells.

Mol Ther 2013 Jun 9;21(6):1242-50. Epub 2013 Apr 9.

Division of Molecular and Clinical Genetics, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1038/mt.2013.60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677303PMC
June 2013

[Regulation of p53-MDM2 pathway by nucleolar stress].

Authors:
Kohichi Kawahara

Seikagaku 2013 Mar;85(3):152-9

Department of Molecular Oncology, Graduate School of Medical and Dental Science Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890-8544, Japan.

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March 2013

Epithelial Pten controls acute lung injury and fibrosis by regulating alveolar epithelial cell integrity.

Am J Respir Crit Care Med 2013 Feb 13;187(3):262-75. Epub 2012 Dec 13.

Division of Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201205-0851O
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http://dx.doi.org/10.1164/rccm.201205-0851OCDOI Listing
February 2013

Tamibarotene: a candidate retinoid drug for Alzheimer's disease.

Biol Pharm Bull 2012 ;35(8):1206-12

Research Foundation ITSUU Laboratory, Tokyo, Japan.

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December 2012

A new PICTure of nucleolar stress.

Cancer Sci 2012 Apr 8;103(4):632-7. Epub 2012 Mar 8.

Division of Cancer Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2012.02219.xDOI Listing
April 2012

Oral administration of synthetic retinoid Am80 (Tamibarotene) decreases brain beta-amyloid peptides in APP23 mice.

Biol Pharm Bull 2009 Jul;32(7):1307-9

Department of Molecular Cell Function, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University.

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July 2009

Marked induction of inducible nitric oxide synthase and tumor necrosis factor-alpha in rat CD40+ microglia by comparison to CD40- microglia.

J Neuroimmunol 2009 Mar 10;208(1-2):70-9. Epub 2009 Feb 10.

Department of Molecular Cell Function, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S016557280900011
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http://dx.doi.org/10.1016/j.jneuroim.2009.01.007DOI Listing
March 2009

IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.

J Immunol 2008 Nov;181(9):6503-13

Department of Molecular Cell Function, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.4049/jimmunol.181.9.6503DOI Listing
November 2008

[Role of PTEN tumor suppressor gene in disease: PTEN-deficient mice].

Seikagaku 2008 Nov;80(11):1017-25

Division of Embryonic and Genetic Engineering, Medical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka, Japan.

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November 2008

alpha-Synuclein aggregates interfere with Parkin solubility and distribution: role in the pathogenesis of Parkinson disease.

J Biol Chem 2008 Mar 14;283(11):6979-87. Epub 2008 Jan 14.

Department of Neurosciences, School of Medicine, University of California at San Diego, La Jolla, California 92039-0624, USA.

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http://dx.doi.org/10.1074/jbc.M710418200DOI Listing
March 2008

Subdomain IIIA of dog albumin contains a binding site similar to site II of human albumin.

Drug Metab Dispos 2008 Jan 9;36(1):81-6. Epub 2007 Oct 9.

Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.1124/dmd.107.016873DOI Listing
January 2008

The Role of alpha-synuclein assembly and metabolism in the pathogenesis of Lewy body disease.

J Mol Neurosci 2004 ;24(3):343-52

Department of Neurosciences, University of California San Diego, La Jolla, CA 92093-0624, USA.

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http://link.springer.com/10.1385/JMN:24:3:343
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http://dx.doi.org/10.1385/JMN:24:3:343DOI Listing
May 2005

[NO-induced apoptosis and ER stress in microglia].

Nihon Yakurigaku Zasshi 2004 Dec;124(6):399-406

Department of Molecular Cell Function, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan.

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December 2004

Molecular assembly and subcellular distribution of ATP-sensitive potassium channel proteins in rat hearts.

FEBS Lett 2003 Sep;552(2-3):259-63

Department of Molecular Cell Function, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, 5-1 Ohe-Honmachi, 862-0973 Kumamoto, Japan.

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September 2003