Publications


In Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling.
Stem Cell Reports 2017 Mar 23;8(3):634-647. Epub 2017 Feb 23.
Laboratory of Stem Cell Differentiation, Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.

Efficient long-term survival of cell grafts after myocardial infarction with thick viable cardiac tissue entirely from pluripotent stem cells.
Sci Rep 2015 Nov 20;5:16842. Epub 2015 Nov 20.
Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.

Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart.
Nat Commun 2014 Jul 29;5:4552. Epub 2014 Jul 29.
1] Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan [2] Core Research for Evolutional Science and Technology (CREST), Japan Science Technology Agency, 4-1-8, Honcho, Kawaguchi, Saitama 332-0012, Japan.

Identification of transcription factors for lineage-specific ESC differentiation.
Stem Cell Reports 2013 27;1(6):545-59. Epub 2013 Nov 27.
Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA ; Department of Systems Medicine, Sakaguchi Laboratory, Keio University School of Medicine, Tokyo 160-8582, Japan ; Japan Science and Technology Agency, CREST, Tokyo160-8582, Japan.

к Opioids inhibit tumor angiogenesis by suppressing VEGF signaling.
Sci Rep 2013 Nov 14;3:3213. Epub 2013 Nov 14.
1] Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan [2] Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan [3] Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA [4].



PKA/CREB signaling triggers initiation of endothelial and hematopoietic cell differentiation via Etv2 induction.
Stem Cells 2012 Apr;30(4):687-96
Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan; Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.

The κ opioid system regulates endothelial cell differentiation and pathfinding in vascular development.
Blood 2011 Jul 1;118(3):775-85. Epub 2011 Apr 1.
Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan.

Cyclosporin-A potently induces highly cardiogenic progenitors from embryonic stem cells.
Biochem Biophys Res Commun 2009 Jan 16;379(1):115-20. Epub 2008 Dec 16.
Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan.

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