Kohei Kaku

Kohei Kaku

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Kohei Kaku

Kohei Kaku

Publications by authors named "Kohei Kaku"

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Dramatic Improvement of Glycemic Control by Promptly Starting Steroid Therapy at an Early Stage of Autoimmune Pancreatitis in a Subject with Type 2 Diabetes.

Intern Med 2019 Dec 31;58(23):3427-3431. Epub 2019 Jul 31.

Department of Diabetes, Metabolism and Endocrinology, Kawasaki Medical School, Japan.

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http://dx.doi.org/10.2169/internalmedicine.3198-19DOI Listing
December 2019

Benefit-Risk Assessment of Alogliptin for the Treatment of Type 2 Diabetes Mellitus.

Drug Saf 2019 Nov;42(11):1311-1327

Global Patient Safety Evaluation Japan, Pharmacovigilance Department, Takeda Pharmaceutical Company Limited, 1-1, Doshomachi 4-chome, Chuo-ku, Osaka, 540-8645, Japan.

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http://dx.doi.org/10.1007/s40264-019-00857-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834733PMC
November 2019

Long-term (52-week) efficacy and safety of ipragliflozin add-on therapy to insulin in Japanese patients with type 1 diabetes mellitus: An uncontrolled, open-label extension of a phase 3 study.

J Diabetes Investig 2019 Nov 19. Epub 2019 Nov 19.

Clinical Pharmacology and Exploratory Development, Astellas Pharma Inc, 2-5-1, Nihonbashi-honcho, Chuo-ku, Tokyo, 103-8411, Japan.

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http://dx.doi.org/10.1111/jdi.13181DOI Listing
November 2019

Safety and effectiveness of empagliflozin in Japanese patients with type 2 diabetes: interim analysis from a post-marketing surveillance study.

Expert Opin Drug Saf 2019 Nov 26:1-11. Epub 2019 Nov 26.

Medicine Division, Nippon Boehringer Ingelheim Co. Ltd, Tokyo, Japan.

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http://dx.doi.org/10.1080/14740338.2020.1694659DOI Listing
November 2019

Efficacy and safety of ipragliflozin add-on therapy to insulin in Japanese patients with type 1 diabetes mellitus: A randomized, double-blind, phase 3 trial.

Diabetes Obes Metab 2019 Oct 11;21(10):2284-2293. Epub 2019 Jul 11.

Clinical Pharmacology and Exploratory Development, Astellas Pharma Inc., Tokyo, Japan.

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http://dx.doi.org/10.1111/dom.13807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772182PMC
October 2019

Attenuation of Weight Loss Through Improved Antilipolytic Effect in Adipose Tissue Via the SGLT2 Inhibitor Tofogliflozin.

J Clin Endocrinol Metab 2019 Sep;104(9):3647-3660

Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, Japan.

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http://dx.doi.org/10.1210/jc.2018-02254DOI Listing
September 2019

Future Possibility of Mizagliflozin on Functional Constipation and/or Irritable Bowel Syndrome With Constipation.

Gastroenterology 2019 09 19;157(3):898-899. Epub 2019 Jun 19.

Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Japan.

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http://dx.doi.org/10.1053/j.gastro.2019.03.075DOI Listing
September 2019

Safety and effectiveness of tofogliflozin in elderly Japanese patients with type 2 diabetes mellitus: A subanalysis of a post-marketing study (J-STEP/EL Study).

J Diabetes Investig 2019 Aug 7. Epub 2019 Aug 7.

Center for Preventive Medicine, The Jikei University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/jdi.13125DOI Listing
August 2019

Severe hypertriglyceridemia in a subject with disturbed life style and poor glycemic control without recurrence of acute pancreatitis: a case report.

BMC Endocr Disord 2019 Aug 30;19(1):92. Epub 2019 Aug 30.

Department of Diabetes, Metabolism and Endocrinology, Kawasaki Medical School, Kurashiki, 701-0192, Japan.

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http://dx.doi.org/10.1186/s12902-019-0425-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717367PMC
August 2019

New concept of the glucagon-like peptide-1 signaling pathway on pancreatic insulin secretion.

Authors:
Kohei Kaku

J Diabetes Investig 2019 Aug 31. Epub 2019 Aug 31.

Department of Medicine, Kawasaki Medical School, Okayama, Japan.

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http://dx.doi.org/10.1111/jdi.13136DOI Listing
August 2019

Renal effects of a sodium-glucose cotransporter 2 inhibitor, tofogliflozin, in relation to sodium intake and glycaemic status.

Diabetes Obes Metab 2019 Jul 6;21(7):1715-1724. Epub 2019 May 6.

Clinical Data Science Department, Kowa Company, Ltd., Tokyo, Japan.

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http://dx.doi.org/10.1111/dom.13731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619387PMC
July 2019

Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in Mice.

Cell Mol Gastroenterol Hepatol 2019 11;7(1):115-134. Epub 2018 Sep 11.

Department of Hepatology and Gastroenterology, Kawasaki Medical School, Kurashiki, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2018.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260362PMC
April 2019

Effect of Mizagliflozin on Postprandial Plasma Glucose in Patients With Functional Constipation.

J Neurogastroenterol Motil 2019 Apr;25(2):332-333

Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Japan.

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http://www.jnmjournal.org/journal/view.html?doi=10.5056/jnm1
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http://dx.doi.org/10.5056/jnm19010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474710PMC
April 2019

Drug fever and acute inflammation from hypercytokinemia triggered by dipeptidyl peptidase-4 inhibitor vildagliptin.

J Diabetes Investig 2019 Jan 2;10(1):182-185. Epub 2018 May 2.

Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan.

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http://doi.wiley.com/10.1111/jdi.12847
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http://dx.doi.org/10.1111/jdi.12847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319481PMC
January 2019

Acute exacerbation of chronic osteomyelitis triggered by aggravation of type 2 diabetes mellitus: a case report.

J Med Case Rep 2019 Jan 7;13(1). Epub 2019 Jan 7.

Department of General Internal Medicine 1, Kawasaki Medical School, 2-6-1 Nakasange, Kita-ku, Okayama, 700-8505, Japan.

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1954-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323657PMC
January 2019

Onset of fulminant type 1 diabetes mellitus under immunotolerance status after long-term therapy for chronic inflammatory demyelinating polyneuropathy.

J Diabetes Investig 2018 Nov 15;9(6):1378-1380. Epub 2018 Jun 15.

Department of Diabetes, Metabolism and Endocrinology, Kawasaki Medical School, Kurashiki, Japan.

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http://dx.doi.org/10.1111/jdi.12796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215944PMC
November 2018

Efficacy and safety of trelagliptin in combination with insulin therapy in Japanese patients with type 2 diabetes: Results from a randomized, Phase IV study.

Diabetes Obes Metab 2018 10 2;20(10):2490-2493. Epub 2018 Jul 2.

Takeda Development Center Japan, Takeda Pharmaceutical Company Limited, Osaka, Japan.

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http://dx.doi.org/10.1111/dom.13397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175153PMC
October 2018

A rare case of large pyosalpinx in an elderly patient with well-controlled type 2 diabetes mellitus: a case report.

J Med Case Rep 2018 Oct 6;12(1):286. Epub 2018 Oct 6.

Department of General Internal Medicine 1, Kawasaki Medical School, 2-6-1 Nakasange, Kita-ku, Okayama, 700-8505, Japan.

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https://jmedicalcasereports.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13256-018-1841-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173840PMC
October 2018

Remission of hyperglycemia after withdrawal of oral antidiabetic drugs in Japanese patients with early-stage type 2 diabetes.

J Diabetes Investig 2018 Sep 13;9(5):1119-1127. Epub 2018 Mar 13.

Division of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Okayama, Japan.

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http://dx.doi.org/10.1111/jdi.12813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123043PMC
September 2018

Sodium-glucose cotransporter 2 inhibitor, tofogliflozin, shows better improvements of blood glucose and insulin secretion in patients with high insulin levels at baseline.

J Diabetes Investig 2018 Jul 13;9(4):862-869. Epub 2017 Nov 13.

Department of Internal Medicine, Kawasaki Medical School, Okayama, Japan.

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http://dx.doi.org/10.1111/jdi.12761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031493PMC
July 2018

Long-term efficacy and safety of canagliflozin in combination with insulin in Japanese patients with type 2 diabetes mellitus.

Diabetes Obes Metab 2018 04 5;20(4):812-820. Epub 2017 Dec 5.

Ikuyaku Integrated Value Development Division, Mitsubishi Tanabe Pharma Corporation, Tokyo, Japan.

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http://dx.doi.org/10.1111/dom.13152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873413PMC
April 2018

Effects of sodium-glucose cotransporter 2 inhibitor, tofogliflozin, on the indices of renal tubular function in patients with type 2 diabetes.

Endocrinol Diabetes Metab 2018 Apr 26;1(2):e00015. Epub 2018 Mar 26.

Clinical Data Science Department Kowa Company, Ltd. Tokyo Japan.

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http://dx.doi.org/10.1002/edm2.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354802PMC
April 2018

Hypoinsulinemic hypoglycemia triggered by liver injury in elderly subjects with low body weight: case reports.

Endocrinol Diabetes Metab Case Rep 2018 23;2018. Epub 2018 Feb 23.

Department of General Internal Medicine 1Kawasaki Medical School, Okayama, Japan.

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http://dx.doi.org/10.1530/EDM-17-0155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825835PMC
February 2018

Non-clostridial gas gangrene in a patient with poorly controlled type 2 diabetes mellitus on hemodialysis.

Acta Diabetol 2018 01 5;55(1):99-101. Epub 2017 Sep 5.

Department of General Internal Medicine 1, Kawasaki Medical School, 2-6-1 Nakasange, Kita-ku, Okayama, 700-8505, Japan.

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http://dx.doi.org/10.1007/s00592-017-1038-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794821PMC
January 2018

Safety evaluation of trelagliptin in the treatment of Japanese type 2 diabetes mellitus patients.

Authors:
Kohei Kaku

Expert Opin Drug Saf 2017 Nov 29;16(11):1313-1322. Epub 2017 Aug 29.

a Department of Internal Medicine , Kawasaki Medical School , Okayama , Japan.

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http://dx.doi.org/10.1080/14740338.2017.1369526DOI Listing
November 2017

Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors and Stroke - Reply.

Circ J 2017 05 10;81(6):899. Epub 2017 May 10.

Boehringer Ingelheim Ltd.

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http://dx.doi.org/10.1253/circj.CJ-17-0395DOI Listing
May 2017

A role of PLC/PKC-dependent pathway in GLP-1-stimulated insulin secretion.

J Mol Med (Berl) 2017 04 17;95(4):361-368. Epub 2017 Jan 17.

Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama, 701-0192, Japan.

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http://dx.doi.org/10.1007/s00109-017-1508-6DOI Listing
April 2017

Clinical course of pituitary function and image in IgG4-related hypophysitis.

Endocrinol Diabetes Metab Case Rep 2017 28;2017. Epub 2017 Apr 28.

Department of General Internal Medicine 1, Kawasaki Medical School, OkayamaJapan.

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http://dx.doi.org/10.1530/EDM-16-0148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409939PMC
April 2017

Temporal lobe epilepsy associated with GAD autoimmunity.

Acta Diabetol 2017 Mar 8;54(3):321-323. Epub 2016 Sep 8.

Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.

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http://dx.doi.org/10.1007/s00592-016-0910-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329084PMC
March 2017

Promising Diabetes Therapy Based on the Molecular Mechanism for Glucose Toxicity: Usefulness of SGLT2 Inhibitors as well as Incretin-Related Drugs.

Curr Med Chem 2016 ;23(27):3044-3051

Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki 701-0192, Japan.

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http://dx.doi.org/10.2174/0929867323666160627102516DOI Listing
February 2017

Insulin Degludec in Clinical Practice: A Review of Japanese Real-World Data.

Diabetes Ther 2017 Feb 13;8(1):189-195. Epub 2017 Jan 13.

Novo Nordisk A/S, Søborg, Denmark.

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http://dx.doi.org/10.1007/s13300-017-0225-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306124PMC
February 2017

Hamman's syndrome triggered by the onset of type 1 diabetes mellitus accompanied by diabetic ketoacidosis.

Acta Diabetol 2016 Dec 13;53(6):1067-1068. Epub 2016 Jun 13.

Department of Diabetes, Metabolism and Endocrinology, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.

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http://dx.doi.org/10.1007/s00592-016-0871-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114339PMC
December 2016

Influence of thyroid volume on the effect of methimazole in Japanese subjects with mild Graves' disease.

Eur J Intern Med 2016 Dec 3;36:e31-e32. Epub 2016 Sep 3.

Department of General Internal Medicine 1, Kawasaki Hospital, Kawasaki Medical School, Japan.

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http://dx.doi.org/10.1016/j.ejim.2016.08.030DOI Listing
December 2016