Koh Ono

Koh Ono

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Koh Ono

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Temporal Trends in the Practice Pattern for Venous Thromboembolism in Japan: Insight From JROAD-DPC.

J Am Heart Assoc 2020 Jan 10;9(2):e014582. Epub 2020 Jan 10.

Department of Cardiovascular Medicine Graduate School of Medicine Kyoto University Kyoto Japan.

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http://dx.doi.org/10.1161/JAHA.119.014582DOI Listing
January 2020

Renal dysfunction and long-term clinical outcomes in patients with venous thromboembolism: From the COMMAND VTE Registry.

Thromb Res 2020 Jan 11;187:39-47. Epub 2020 Jan 11.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2020.01.005DOI Listing
January 2020

Effects of Metformin on Left Ventricular Size and Function in Hypertensive Patients with Type 2 Diabetes Mellitus: Results of a Randomized, Controlled, Multicenter, Phase IV Trial.

Am J Cardiovasc Drugs 2019 Nov 13. Epub 2019 Nov 13.

Clinical Research Institute, National Hospital Organization Kyoto Medical Center, 1-1 Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto, 612-8555, Japan.

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http://dx.doi.org/10.1007/s40256-019-00381-1DOI Listing
November 2019

More- Versus Less-Intensive Lipid-Lowering Therapy.

Circ Cardiovasc Qual Outcomes 2019 Aug 15;12(8):e005460. Epub 2019 Aug 15.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan (Y.Y., H.S., T.K., T.A.M., Y.N., N.S., S.S., K.O., T.K.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.118.005460DOI Listing
August 2019

Therapeutic angiogenesis by local sustained release of microRNA-126 using poly lactic-co-glycolic acid nanoparticles in murine hindlimb ischemia.

J Vasc Surg 2018 10 11;68(4):1209-1215. Epub 2017 Dec 11.

Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.jvs.2017.08.097DOI Listing
October 2018

SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo.

Arterioscler Thromb Vasc Biol 2018 10;38(10):2460-2473

From the Departments of Cardiovascular Medicine (T.N., T.H., O.B., N.S., R.H., Y.K., T.N., M.N., H.N., Y.N., F.N., Y.I., S.K., M.K., T.K., K.O.), Graduate School of Medicine, Kyoto University, Japan.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.118.311409
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http://dx.doi.org/10.1161/ATVBAHA.118.311409DOI Listing
October 2018

Preclinical evaluation of a paclitaxel-incorporated nanoparticle-coated balloon in rabbit and porcine models.

Cardiovasc Revasc Med 2018 06 19;19(4):433-437. Epub 2017 Oct 19.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.carrev.2017.10.007DOI Listing
June 2018

Asian patients versus non-Asian patients in the efficacy and safety of direct oral anticoagulants relative to vitamin K antagonist for venous thromboembolism: A systemic review and meta-analysis.

Thromb Res 2018 06 10;166:37-42. Epub 2018 Apr 10.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.04.008DOI Listing
June 2018

Long Non-Coding RNAs as Key Regulators of Cardiovascular Diseases.

Circ J 2018 04 10;82(5):1231-1236. Epub 2018 Mar 10.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University.

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http://dx.doi.org/10.1253/circj.CJ-18-0169DOI Listing
April 2018

Association between monocyte chemoattractant protein-1 and blood pressure in smokers.

J Int Med Res 2018 Mar 3;46(3):965-974. Epub 2017 Nov 3.

1 Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.

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http://dx.doi.org/10.1177/0300060517723415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972233PMC
March 2018

Smoking cessation reduces the lectin-like low-density lipoprotein receptor index, an independent cardiovascular risk marker of vascular inflammation.

Heart Vessels 2018 Jan 31;33(1):9-16. Epub 2017 Jul 31.

Division of Translational Research, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, 1-1 Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto, 612-8555, Japan.

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http://dx.doi.org/10.1007/s00380-017-1026-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736764PMC
January 2018

Imbalanced expression of polycistronic miRNA in acute myeloid leukemia.

Int J Hematol 2017 Dec 22;106(6):811-819. Epub 2017 Aug 22.

Division of Hematological Malignancy, Institute of Medical Sciences, Tokai University, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.

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http://dx.doi.org/10.1007/s12185-017-2314-1DOI Listing
December 2017

Impact of Transient or Persistent Contrast-induced Nephropathy on Long-term Mortality After Elective Percutaneous Coronary Intervention.

Am J Cardiol 2017 Dec 19;120(12):2146-2153. Epub 2017 Sep 19.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.amjcard.2017.08.036DOI Listing
December 2017

Asymptomatic Lower Extremity Deep Vein Thrombosis - Clinical Characteristics, Management Strategies, and Long-Term Outcomes.

Circ J 2017 Nov 27;81(12):1936-1944. Epub 2017 Jun 27.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University.

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http://dx.doi.org/10.1253/circj.CJ-17-0445DOI Listing
November 2017

Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.

Arterioscler Thromb Vasc Biol 2017 11 7;37(11):2161-2170. Epub 2017 Sep 7.

From the Departments of Cardiovascular Medicine (T.N., T.H., O.B., M.N., T.N., M.I., Y.K., H.N., S.U., F.N., Y.I., S.K., M.K., N.S., T.K., K.O.) and Cardiovascular Surgery (K.S., K.M.), Graduate School of Medicine, Kyoto University, Japan; The Cardiovascular Research Institute, Kurume University, Japan (S.O., H.A.); and Division of Translational Research, National Hospital Organization, Kyoto Medical Center, Japan.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.117.309768
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http://dx.doi.org/10.1161/ATVBAHA.117.309768DOI Listing
November 2017

Nardilysin is a promising biomarker for the early diagnosis of acute coronary syndrome.

Int J Cardiol 2017 Sep;243:1-8

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan; Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.04.047DOI Listing
September 2017

MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol.

Circ Res 2017 Mar 5;120(5):835-847. Epub 2016 Dec 5.

From the Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Japan (M.N., T.H., Y.K., O.B., T.Nakao, T.Nishino, D.H., Y.N., H.N., F.N., Y.I., S.K., M.K., R.H., T.Kimura, K.O.); Department of Cardiovascular Center, Osaka Red Cross Hospital, Japan (K.N., T.I.); Department of Pharmacology, Kansai Medical University, Hirakata, Osaka, Japan (T.Nakamura); Division of Translational Research, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Japan (K.H.); Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University of Medicine, Indianapolis (S.J.C.); and Kobe City Medical Center General Hospital, Japan (T.Kita).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.309528DOI Listing
March 2017

Cardiac and Noncardiac Causes of Long-Term Mortality in ST-Segment-Elevation Acute Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention.

Circ Cardiovasc Qual Outcomes 2017 01;10(1)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan (Y.Y., H.S., H.Y., S.S., K.O., T.K.), Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T.M.); Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan (Y.F.); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (K.A.); Division of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K.K.); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M.A.); and Division of Cardiology, Osaka Red Cross Hospital, Osaka, Japan (K.N.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.116.002790DOI Listing
January 2017

A Novel Link between Plasma MicroRNA-33b Levels and Lipid Disorders in Diabetes Mellitus.

Authors:
Koh Ono

J Atheroscler Thromb 2016 Nov 29;23(11):1259-1260. Epub 2016 Jul 29.

Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine.

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http://dx.doi.org/10.5551/jat.ED056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113742PMC
November 2016

Emerging Novel Biomarkers for Arteriosclerosis Obliterans.

J Atheroscler Thromb 2016 2;23(2):171-2. Epub 2015 Dec 2.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University.

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http://dx.doi.org/10.5551/jat.ED028DOI Listing
August 2016

MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development.

Cancer Res 2016 08 3;76(15):4383-93. Epub 2016 Jun 3.

Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2926DOI Listing
August 2016

microRNAs and Cardiovascular Remodeling.

Authors:
Koh Ono

Adv Exp Med Biol 2015 ;888:197-213

Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1007/978-3-319-22671-2_10DOI Listing
May 2016

Effects of Age and Sex on Clinical Outcomes After Percutaneous Coronary Intervention Relative to Coronary Artery Bypass Grafting in Patients With Triple-Vessel Coronary Artery Disease.

Circulation 2016 May 23;133(19):1878-91. Epub 2016 Mar 23.

From Division of Cardiology (K.Y., K.A., S.S.) and Division of Cardiovascular Surgery (M.H.), Kokura Memorial Hospital, Kitakyushu, Japan; Department of Cardiovascular Medicine (H.S., K.N., T.T., K.O., H.W., T. Kimura) and Department of Cardiovascular Surgery (R.S.), Kyoto University Graduate School of Medicine, Japan; Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T.M.); Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Japan (Y.F.); Division of Cardiology, Tenri Hospital, Japan (Y.N.); Department of Cardiology (K.K.) and Division of Cardiovascular Surgery (T. Komiya), Kurashiki Central Hospital, Japan; Division of Cardiology, Shizuoka City Shizuoka Hospital, Japan (T.O.); Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); and Division of Cardiovascular Surgery, Nara Hospital, Kinki University Faculty of Medicine, Nara, Japan (N.N.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020955DOI Listing
May 2016

MicroRNA-133a in the Development of Arteriosclerosis Obliterans.

Authors:
Koh Ono

J Atheroscler Thromb 2015 27;22(4):342-3. Epub 2015 Feb 27.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University.

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http://dx.doi.org/10.5551/jat.ED006DOI Listing
March 2016

Functions of microRNA-33a/b and microRNA therapeutics.

Authors:
Koh Ono

J Cardiol 2016 Jan 29;67(1):28-33. Epub 2015 Nov 29.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jjcc.2015.10.017DOI Listing
January 2016

Clinical impact of left ventricular outflow tract obstruction in takotsubo cardiomyopathy.

Circ J 2015 28;79(4):839-46. Epub 2015 Jan 28.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University.

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http://dx.doi.org/10.1253/circj.CJ-14-1148DOI Listing
December 2015

Influence of Sex on Long-Term Outcomes After Implantation of Bare-Metal Stent: A Multicenter Report From the Coronary Revascularization Demonstrating Outcome Study-Kyoto (CREDO-Kyoto) Registry Cohort-1.

Circulation 2015 Dec 6;132(24):2323-33. Epub 2015 Oct 6.

From Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (K.Y., K.A., S. Shirai); Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (H.S., T.T., K.O., H.W., T.K.); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T.M.); Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan (Y.F.); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K.K.); Division of Cardiology, Maizuru Kyosai Hospital, Maizuru, Japan (M.K.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y.T.); Division of Cardiology, Shizuoka General Hospital, Shizuoka, Japan (O.D., H.K.); Division of Cardiology, Juntendo University Shizuoka Hospital, Shizuoka, Japan (S. Suwa); Division of Cardiology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan (T.O.); and Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.115.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.017168DOI Listing
December 2015

[Regulation of lipid metabolism by miRNAs and transcription factors].

Authors:
Koh Ono

Seikagaku 2015 Dec;87(6):733-5

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December 2015

MicroRNA-33a/b in lipid metabolism – novel “thrifty” models.

Circ J 2015 8;79(2):278-84. Epub 2015 Jan 8.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1253/circj.CJ-14-1252DOI Listing
November 2015

microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.

J Neurosci 2015 Nov;35(44):14717-26

Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida 32224, Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, Missouri 63110,

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http://www.jneurosci.org/content/35/44/14717.full.pdf
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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2053-15.2
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http://dx.doi.org/10.1523/JNEUROSCI.2053-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635126PMC
November 2015

MicroRNAs and High-Density Lipoprotein Cholesterol Metabolism.

Int Heart J 2015 18;56(4):365-71. Epub 2015 Jun 18.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University.

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http://dx.doi.org/10.1536/ihj.15-019DOI Listing
September 2015

Long-term clinical outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease.

Cardiovasc Interv Ther 2015 Jul 7;30(3):189-97. Epub 2014 Sep 7.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

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http://link.springer.com/content/pdf/10.1007/s12928-014-0297
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http://link.springer.com/10.1007/s12928-014-0297-x
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http://dx.doi.org/10.1007/s12928-014-0297-xDOI Listing
July 2015

MicroRNA-451 exacerbates lipotoxicity in cardiac myocytes and high-fat diet-induced cardiac hypertrophy in mice through suppression of the LKB1/AMPK pathway.

Circ Res 2015 Jan 31;116(2):279-88. Epub 2014 Oct 31.

From the Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan (Y.K., T.H., O.B., S.W., M.N., S.U., M.I., T. Nakao, T. Nishino, T.Kimura., K.Ono.); Cardiovascular Division, The James Black Centre, King's College London, London, United Kingdom (K.Otsu.); and Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo Prefecture, Japan (T.Kita.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.116.30470
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http://dx.doi.org/10.1161/CIRCRESAHA.116.304707DOI Listing
January 2015

Effect of statin therapy on cardiovascular outcomes after coronary revascularization in patients ≥ 80 years of age: observations from the CREDO-Kyoto Registry Cohort-2.

Atherosclerosis 2014 Dec 4;237(2):821-8. Epub 2014 Nov 4.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.10.108DOI Listing
December 2014

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice.

Nat Commun 2013 ;4:2883

1] Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan [2] Department of Clinical Innovative Medicine, Institute for Advancement of Clinical and Translational Science, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan [3].

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http://dx.doi.org/10.1038/ncomms3883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863899PMC
October 2014

Incidence and outcome of surgical procedures after coronary artery bypass grafting compared with those after percutaneous coronary intervention: a report from the Coronary Revascularization Demonstrating Outcome Study in Kyoto PCI/CABG Registry Cohort-2.

Circ Cardiovasc Interv 2014 Aug 29;7(4):482-91. Epub 2014 Jul 29.

From the Department of Cardiovascular Medicine and Hypertension (A.T., S.H., M.O.), and Cardiovascular and Gastoroenterological Surgery, Advanced Therapeutics Cardiovascular and Respiratory Disorders (Y.I.), Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan; Department of Cardiovascular Medicine (H.S., K.O., S.S., T.T., J.T., Y.K., M. Hayano, T. Kimura), and Department of Cardiovascular Surgery (R.S.), Graduate School of Medicine, Kyoto University, Kyoto, Japan; Division of General Medicine, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan (T.M.); Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Hyogo, Japan (Y.F., T. Kita); Division of Cardiology, Tenri Hospital, Nara, Japan (Y.N.); Division of Cardiology, Kurashiki Central Hospital, Okayama, Japan (K.K., K.M.); Division of Cardiology (K.A., M.N.) and Division of Cardiovascular Surgery (M. Hanyu), Kokura Memorial Hospital, Fukuoka, Japan; Division of Cardiology, Kyoto Medical Center, Kyoto, Japan (M.A.); Division of Cardiology, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan (H.N.); Department of Cardiovascular Surgery, Iwate Medical University, Iwate, Japan (H.O.); Division of Cardiovascular Surgery, Shizuoka City Shizuoka Hospital, Shizuoka City Japan (M.S.); Division of Cardiovascular Surgery, Nara Hospital, Kinki University Faculty of Medicine, Osaka, Japan (N.N.); and Division of Cardiovascular Surgery, Kurashiki Central Hospital, Okayama, Japan (T. Komiya).

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https://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.11
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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.113.001056DOI Listing
August 2014

Seeing is believing - Imaging of a plaque in the renal artery.

Authors:
Koh Ono

J Cardiol Cases 2014 Feb 13;9(2):84-85. Epub 2013 Dec 13.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.jccase.2013.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277988PMC
February 2014

[Diagnosis and therapy of atherosclerosis through molecular biological approaches possibility of HDL-targeting therapy by manipulation of micro RNA-33].

Authors:
Koh Ono

Rinsho Byori 2013 Oct;61(10):934-9

Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.

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October 2013