Ko Willems van Dijk

Ko Willems van Dijk

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Ko Willems van Dijk

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Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study.

J Clin Lipidol 2018 Jan - Feb;12(1):137-144.e1. Epub 2017 Nov 2.

Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.jacl.2017.10.023DOI Listing
July 2019

Associations of Outdoor Temperature, Bright Sunlight, and Cardiometabolic Traits in Two European Population-Based Cohorts.

J Clin Endocrinol Metab 2019 Jul;104(7):2903-2910

Radcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1210/jc.2018-02532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543772PMC
July 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.

Authors:
Cassandra N Spracklen Tugce Karaderi Hanieh Yaghootkar Claudia Schurmann Rebecca S Fine Zoltan Kutalik Michael H Preuss Yingchang Lu Laura B L Wittemans Linda S Adair Matthew Allison Najaf Amin Paul L Auer Traci M Bartz Matthias Blüher Michael Boehnke Judith B Borja Jette Bork-Jensen Linda Broer Daniel I Chasman Yii-Der Ida Chen Paraskevi Chirstofidou Ayse Demirkan Cornelia M van Duijn Mary F Feitosa Melissa E Garcia Mariaelisa Graff Harald Grallert Niels Grarup Xiuqing Guo Jeffrey Haesser Torben Hansen Tamara B Harris Heather M Highland Jaeyoung Hong M Arfan Ikram Erik Ingelsson Rebecca Jackson Pekka Jousilahti Mika Kähönen Jorge R Kizer Peter Kovacs Jennifer Kriebel Markku Laakso Leslie A Lange Terho Lehtimäki Jin Li Ruifang Li-Gao Lars Lind Jian'an Luan Leo-Pekka Lyytikäinen Stuart MacGregor David A Mackey Anubha Mahajan Massimo Mangino Satu Männistö Mark I McCarthy Barbara McKnight Carolina Medina-Gomez James B Meigs Sophie Molnos Dennis Mook-Kanamori Andrew P Morris Renee de Mutsert Mike A Nalls Ivana Nedeljkovic Kari E North Craig E Pennell Aruna D Pradhan Michael A Province Olli T Raitakari Chelsea K Raulerson Alex P Reiner Paul M Ridker Samuli Ripatti Neil Roberston Jerome I Rotter Veikko Salomaa America A Sandoval-Zárate Colleen M Sitlani Tim D Spector Konstantin Strauch Michael Stumvoll Kent D Taylor Betina Thuesen Anke Tönjes Andre G Uitterlinden Cristina Venturini Mark Walker Carol A Wang Shuai Wang Nicholas J Wareham Sara M Willems Ko Willems van Dijk James G Wilson Ying Wu Jie Yao Kristin L Young Claudia Langenberg Timothy M Frayling Tuomas O Kilpeläinen Cecilia M Lindgren Ruth J F Loos Karen L Mohlke

Am J Hum Genet 2019 Jul 6;105(1):15-28. Epub 2019 Jun 6.

Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612516PMC
July 2019

The association of genetic variants in the cholesteryl ester transfer protein gene with hemostatic factors and a first venous thrombosis.

J Thromb Haemost 2019 May 31. Epub 2019 May 31.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/jth.14528DOI Listing
May 2019

Repeat length variations in polyglutamine disease-associated genes affect body mass index.

Int J Obes (Lond) 2019 03 17;43(3):440-449. Epub 2018 Aug 17.

Department of Neurology, Leiden University Medical Centre, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41366-018-0161-7DOI Listing
March 2019

Proteoglycan 4 deficiency protects against glucose intolerance and fatty liver disease in diet-induced obese mice.

Biochim Biophys Acta Mol Basis Dis 2019 Feb 15;1865(2):494-501. Epub 2018 Nov 15.

Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Gorlaeus Laboratories, Leiden University, 2333CC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2018.11.009DOI Listing
February 2019

GC-MS Analysis of Short-Chain Fatty Acids in Feces, Cecum Content, and Blood Samples.

Methods Mol Biol 2018 ;1730:247-256

Center for Proteomics and Metabolomics, Leiden University Medical Center (LUMC), Leiden, The Netherlands.

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http://link.springer.com/10.1007/978-1-4939-7592-1_17
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http://dx.doi.org/10.1007/978-1-4939-7592-1_17DOI Listing
December 2018

GC-MS Analysis of Medium- and Long-Chain Fatty Acids in Blood Samples.

Methods Mol Biol 2018 ;1730:257-265

Center for Proteomics and Metabolomics, Leiden University Medical Center (LUMC), Leiden, The Netherlands.

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http://link.springer.com/10.1007/978-1-4939-7592-1_18
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http://dx.doi.org/10.1007/978-1-4939-7592-1_18DOI Listing
December 2018

Sex differences in body fat distribution are related to sex differences in serum leptin and adiponectin.

Peptides 2018 09 1;107:25-31. Epub 2018 Aug 1.

Department of Clinical Epidemiology, Leiden University Medical Center (LUMC), PO-Box 9600, 2300RC, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2018.07.008DOI Listing
September 2018

Fusing metabolomics data sets with heterogeneous measurement errors.

PLoS One 2018 26;13(4):e0195939. Epub 2018 Apr 26.

Biosystems Data Analysis, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195939PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919515PMC
July 2018

Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota.

Diabetologia 2018 06 3;61(6):1447-1458. Epub 2018 Mar 3.

Nutrition, Metabolism and Genomics Group, Division of Human Nutrition and Health, Wageningen University, Stippeneng 4, 6708 WE, Wageningen, the Netherlands.

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http://dx.doi.org/10.1007/s00125-018-4583-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449003PMC
June 2018

In vivo and in silico dynamics of the development of Metabolic Syndrome.

PLoS Comput Biol 2018 06 7;14(6):e1006145. Epub 2018 Jun 7.

Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.

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http://dx.doi.org/10.1371/journal.pcbi.1006145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991635PMC
June 2018

Genetics of fasting and postprandial metabolite levels are overlapping.

Physiol Genomics 2018 04 26;50(4):235-236. Epub 2018 Jan 26.

Department of Clinical Epidemiology; Leiden University Medical Center , Leiden , the Netherlands.

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http://dx.doi.org/10.1152/physiolgenomics.00101.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966804PMC
April 2018

Relation of Overall and Abdominal Adiposity With Electrocardiogram Parameters of Subclinical Cardiovascular Disease in Individuals Aged 45 to 65 Years (from the Netherlands Epidemiology of Obesity Study).

Am J Cardiol 2018 03 11;121(5):570-578. Epub 2017 Dec 11.

Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00029149173185
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http://dx.doi.org/10.1016/j.amjcard.2017.11.030DOI Listing
March 2018

The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice.

Nutrients 2018 Feb 3;10(2). Epub 2018 Feb 3.

Department of Human Genetics and Einthoven Laboratory for Experimental Medicine, Leiden University Medical Center (LUMC), 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.3390/nu10020172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852748PMC
February 2018

A Mendelian Randomization Study of Metabolite Profiles, Fasting Glucose, and Type 2 Diabetes.

Diabetes 2017 11 28;66(11):2915-2926. Epub 2017 Aug 28.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands

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http://dx.doi.org/10.2337/db17-0199DOI Listing
November 2017

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.

Authors:
Felix R Day Deborah J Thompson Hannes Helgason Daniel I Chasman Hilary Finucane Patrick Sulem Katherine S Ruth Sean Whalen Abhishek K Sarkar Eva Albrecht Elisabeth Altmaier Marzyeh Amini Caterina M Barbieri Thibaud Boutin Archie Campbell Ellen Demerath Ayush Giri Chunyan He Jouke J Hottenga Robert Karlsson Ivana Kolcic Po-Ru Loh Kathryn L Lunetta Massimo Mangino Brumat Marco George McMahon Sarah E Medland Ilja M Nolte Raymond Noordam Teresa Nutile Lavinia Paternoster Natalia Perjakova Eleonora Porcu Lynda M Rose Katharina E Schraut Ayellet V Segrè Albert V Smith Lisette Stolk Alexander Teumer Irene L Andrulis Stefania Bandinelli Matthias W Beckmann Javier Benitez Sven Bergmann Murielle Bochud Eric Boerwinkle Stig E Bojesen Manjeet K Bolla Judith S Brand Hiltrud Brauch Hermann Brenner Linda Broer Thomas Brüning Julie E Buring Harry Campbell Eulalia Catamo Stephen Chanock Georgia Chenevix-Trench Tanguy Corre Fergus J Couch Diana L Cousminer Angela Cox Laura Crisponi Kamila Czene George Davey Smith Eco J C N de Geus Renée de Mutsert Immaculata De Vivo Joe Dennis Peter Devilee Isabel Dos-Santos-Silva Alison M Dunning Johan G Eriksson Peter A Fasching Lindsay Fernández-Rhodes Luigi Ferrucci Dieter Flesch-Janys Lude Franke Marike Gabrielson Ilaria Gandin Graham G Giles Harald Grallert Daniel F Gudbjartsson Pascal Guénel Per Hall Emily Hallberg Ute Hamann Tamara B Harris Catharina A Hartman Gerardo Heiss Maartje J Hooning John L Hopper Frank Hu David J Hunter M Arfan Ikram Hae Kyung Im Marjo-Riitta Järvelin Peter K Joshi David Karasik Manolis Kellis Zoltan Kutalik Genevieve LaChance Diether Lambrechts Claudia Langenberg Lenore J Launer Joop S E Laven Stefania Lenarduzzi Jingmei Li Penelope A Lind Sara Lindstrom YongMei Liu Jian'an Luan Reedik Mägi Arto Mannermaa Hamdi Mbarek Mark I McCarthy Christa Meisinger Thomas Meitinger Cristina Menni Andres Metspalu Kyriaki Michailidou Lili Milani Roger L Milne Grant W Montgomery Anna M Mulligan Mike A Nalls Pau Navarro Heli Nevanlinna Dale R Nyholt Albertine J Oldehinkel Tracy A O'Mara Sandosh Padmanabhan Aarno Palotie Nancy Pedersen Annette Peters Julian Peto Paul D P Pharoah Anneli Pouta Paolo Radice Iffat Rahman Susan M Ring Antonietta Robino Frits R Rosendaal Igor Rudan Rico Rueedi Daniela Ruggiero Cinzia F Sala Marjanka K Schmidt Robert A Scott Mitul Shah Rossella Sorice Melissa C Southey Ulla Sovio Meir Stampfer Maristella Steri Konstantin Strauch Toshiko Tanaka Emmi Tikkanen Nicholas J Timpson Michela Traglia Thérèse Truong Jonathan P Tyrer André G Uitterlinden Digna R Velez Edwards Veronique Vitart Uwe Völker Peter Vollenweider Qin Wang Elisabeth Widen Ko Willems van Dijk Gonneke Willemsen Robert Winqvist Bruce H R Wolffenbuttel Jing Hua Zhao Magdalena Zoledziewska Marek Zygmunt Behrooz Z Alizadeh Dorret I Boomsma Marina Ciullo Francesco Cucca Tõnu Esko Nora Franceschini Christian Gieger Vilmundur Gudnason Caroline Hayward Peter Kraft Debbie A Lawlor Patrik K E Magnusson Nicholas G Martin Dennis O Mook-Kanamori Ellen A Nohr Ozren Polasek David Porteous Alkes L Price Paul M Ridker Harold Snieder Tim D Spector Doris Stöckl Daniela Toniolo Sheila Ulivi Jenny A Visser Henry Völzke Nicholas J Wareham James F Wilson Amanda B Spurdle Unnur Thorsteindottir Katherine S Pollard Douglas F Easton Joyce Y Tung Jenny Chang-Claude David Hinds Anna Murray Joanne M Murabito Kari Stefansson Ken K Ong John R B Perry

Nat Genet 2017 Jun 24;49(6):834-841. Epub 2017 Apr 24.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841952PMC
June 2017

Weight loss induced by very low calorie diet is associated with a more beneficial systemic inflammatory profile than by Roux-en-Y gastric bypass.

Metabolism 2016 Nov 16;65(11):1614-1620. Epub 2016 Aug 16.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2016.07.013DOI Listing
November 2016

Energy restriction and Roux-en-Y gastric bypass reduce postprandial α-dicarbonyl stress in obese women with type 2 diabetes.

Diabetologia 2016 09 16;59(9):2013-7. Epub 2016 Jun 16.

Department of Internal Medicine, Laboratory for Metabolism and Vascular Medicine, Maastricht University Medical Center, Peter Debeyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, the Netherlands.

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http://link.springer.com/10.1007/s00125-016-4009-1
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http://dx.doi.org/10.1007/s00125-016-4009-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969347PMC
September 2016

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.

Authors:
Elisabeth M van Leeuwen Aniko Sabo Joshua C Bis Jennifer E Huffman Ani Manichaikul Albert V Smith Mary F Feitosa Serkalem Demissie Peter K Joshi Qing Duan Jonathan Marten Jan B van Klinken Ida Surakka Ilja M Nolte Weihua Zhang Hamdi Mbarek Ruifang Li-Gao Stella Trompet Niek Verweij Evangelos Evangelou Leo-Pekka Lyytikäinen Bamidele O Tayo Joris Deelen Peter J van der Most Sander W van der Laan Dan E Arking Alanna Morrison Abbas Dehghan Oscar H Franco Albert Hofman Fernando Rivadeneira Eric J Sijbrands Andre G Uitterlinden Josyf C Mychaleckyj Archie Campbell Lynne J Hocking Sandosh Padmanabhan Jennifer A Brody Kenneth M Rice Charles C White Tamara Harris Aaron Isaacs Harry Campbell Leslie A Lange Igor Rudan Ivana Kolcic Pau Navarro Tatijana Zemunik Veikko Salomaa Angad S Kooner Jaspal S Kooner Benjamin Lehne William R Scott Sian-Tsung Tan Eco J de Geus Yuri Milaneschi Brenda W J H Penninx Gonneke Willemsen Renée de Mutsert Ian Ford Ron T Gansevoort Marcelo P Segura-Lepe Olli T Raitakari Jorma S Viikari Kjell Nikus Terrence Forrester Colin A McKenzie Anton J M de Craen Hester M de Ruijter Gerard Pasterkamp Harold Snieder Albertine J Oldehinkel P Eline Slagboom Richard S Cooper Mika Kähönen Terho Lehtimäki Paul Elliott Pim van der Harst J Wouter Jukema Dennis O Mook-Kanamori Dorret I Boomsma John C Chambers Morris Swertz Samuli Ripatti Ko Willems van Dijk Veronique Vitart Ozren Polasek Caroline Hayward James G Wilson James F Wilson Vilmundur Gudnason Stephen S Rich Bruce M Psaty Ingrid B Borecki Eric Boerwinkle Jerome I Rotter L Adrienne Cupples Cornelia M van Duijn

J Med Genet 2016 07 1;53(7):441-9. Epub 2016 Apr 1.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1136/jmedgenet-2015-103439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941146PMC
July 2016

FluxModeCalculator: an efficient tool for large-scale flux mode computation.

Bioinformatics 2016 04 18;32(8):1265-6. Epub 2015 Dec 18.

Department of Human Genetics Einthoven Laboratory for Experimental Vascular Medicine Department of Medicine, Division of Endocrinology, LUMC, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/btv742DOI Listing
April 2016

Serum CETP concentration is not associated with measures of body fat: The NEO study.

Atherosclerosis 2016 Mar 19;246:267-73. Epub 2016 Jan 19.

Department of Medicine, Division of Endocrinology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.01.031DOI Listing
March 2016

Reanalysis of mGWAS results and in vitro validation show that lactate dehydrogenase interacts with branched-chain amino acid metabolism.

Eur J Hum Genet 2016 Jan 27;24(1):142-5. Epub 2015 May 27.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2015.106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795225PMC
January 2016

Type 2 diabetes is associated with postprandial amino acid measures.

Arch Biochem Biophys 2016 Jan 10;589:138-44. Epub 2015 Aug 10.

Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.abb.2015.08.003DOI Listing
January 2016

Physiological changes due to mild cooling in healthy lean males of white Caucasian and South Asian descent: A metabolomics study.

Arch Biochem Biophys 2016 Jan 16;589:152-7. Epub 2015 Sep 16.

Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Epidemiology Section, BESC Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.1016/j.abb.2015.09.001DOI Listing
January 2016

FcRγ-chain deficiency reduces the development of diet-induced obesity.

Obesity (Silver Spring) 2015 Dec 2;23(12):2435-44. Epub 2015 Nov 2.

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1002/oby.21309DOI Listing
December 2015

Effects of low-stearate palm oil and high-stearate lard high-fat diets on rat liver lipid metabolism and glucose tolerance.

Nutr Metab (Lond) 2015 18;12:57. Epub 2015 Dec 18.

Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, The Netherlands.

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http://dx.doi.org/10.1186/s12986-015-0053-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683731PMC
December 2015

Anacetrapib reduces (V)LDL cholesterol by inhibition of CETP activity and reduction of plasma PCSK9.

J Lipid Res 2015 Nov 4;56(11):2085-93. Epub 2015 Sep 4.

Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://www.jlr.org/content/56/11/2085.full.pdf
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http://www.jlr.org/lookup/doi/10.1194/jlr.M057794
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http://dx.doi.org/10.1194/jlr.M057794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617395PMC
November 2015

Smoking is associated with increased resting energy expenditure in the general population: The NEO study.

Metabolism 2015 Nov 18;64(11):1548-55. Epub 2015 Aug 18.

Department of Medicine, Division of Endocrinology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands; Department of Epidemiology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands; Department of Clinical Epidemiology, Aarhus University, DK-8000 Aarhus C, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S00260495150022
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http://dx.doi.org/10.1016/j.metabol.2015.08.008DOI Listing
November 2015

Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice.

FASEB J 2015 Jul 7;29(7):3027-39. Epub 2015 Apr 7.

Departments of *Parasitology, Human Genetics, Molecular Cell Biology, and Endocrinology and Metabolic Diseases, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands

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http://dx.doi.org/10.1096/fj.14-266239DOI Listing
July 2015

Fiber-type-specific sensitivities and phenotypic adaptations to dietary fat overload differentially impact fast- versus slow-twitch muscle contractile function in C57BL/6J mice.

J Nutr Biochem 2015 Feb 25;26(2):155-64. Epub 2014 Oct 25.

Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, NL-5600 MB Eindhoven, The Netherlands; Netherlands Consortium for Systems Biology, PO Box 94215, NL-1090GE Amsterdam, The Netherlands; Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1, Building 3226, 9713 AV Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jnutbio.2014.09.014DOI Listing
February 2015

Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses.

PLoS Genet 2015 Jan 8;11(1):e1004835. Epub 2015 Jan 8.

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands; Department of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1004835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287344PMC
January 2015

Calorie restriction and Roux-en-Y gastric bypass have opposing effects on circulating FGF21 in morbidly obese subjects.

Clin Endocrinol (Oxf) 2014 Dec 12;81(6):862-70. Epub 2014 Jun 12.

Department of Endocrinology and Metabolism, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/cen.12496DOI Listing
December 2014

Roux-en-Y gastric bypass surgery, but not calorie restriction, reduces plasma branched-chain amino acids in obese women independent of weight loss or the presence of type 2 diabetes.

Diabetes Care 2014 Dec 14;37(12):3150-6. Epub 2014 Oct 14.

Department of Endocrinology and Metabolism, Leiden University Medical Center, Leiden, the Netherlands Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands Einthoven Laboratory for Experimental Vascular Medicine, Leiden, the Netherlands.

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http://dx.doi.org/10.2337/dc14-0195DOI Listing
December 2014

Prolonged niacin treatment leads to increased adipose tissue PUFA synthesis and anti-inflammatory lipid and oxylipin plasma profile.

J Lipid Res 2014 Dec 15;55(12):2532-40. Epub 2014 Oct 15.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1194/jlr.M051938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242446PMC
December 2014

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

Am J Physiol Endocrinol Metab 2014 Nov 23;307(10):E885-95. Epub 2014 Sep 23.

Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands; Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands

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http://dx.doi.org/10.1152/ajpendo.00215.2014DOI Listing
November 2014

Genetics of the human metabolome, what is next?

Biochim Biophys Acta 2014 Oct 4;1842(10):1923-1931. Epub 2014 Jun 4.

Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands; Department of Endocrinology, Leiden University Medical Center, Leiden, Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439140015
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http://dx.doi.org/10.1016/j.bbadis.2014.05.030DOI Listing
October 2014

BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality.

PLoS One 2013 16;8(9):e74083. Epub 2013 Sep 16.

Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands ; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074083PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774620PMC
May 2014

Increased systemic and adipose tissue inflammation differentiates obese women with T2DM from obese women with normal glucose tolerance.

Metabolism 2014 Apr 10;63(4):492-501. Epub 2013 Dec 10.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2013.12.002DOI Listing
April 2014

Heritability of dietary food intake patterns.

Acta Diabetol 2013 Oct 15;50(5):721-6. Epub 2012 Mar 15.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://link.springer.com/10.1007/s00592-012-0387-0
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http://dx.doi.org/10.1007/s00592-012-0387-0DOI Listing
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October 2013

CD36 is important for adipocyte recruitment and affects lipolysis.

Obesity (Silver Spring) 2013 Oct 29;21(10):2037-45. Epub 2013 May 29.

Department of General Internal Medicine, Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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October 2013

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes.

Diabetes 2013 Oct 8;62(10):3589-98. Epub 2013 Jul 8.

Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781444PMC
October 2013

Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals.

Am J Physiol Endocrinol Metab 2013 May 19;304(9):E1012-21. Epub 2013 Mar 19.

Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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May 2013

Practical aspects of estimating energy components in rodents.

Front Physiol 2013 1;4:94. Epub 2013 May 1.

Department of Human Genetics, Leiden University Medical Center Leiden, Netherlands.

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May 2013

Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity.

FASEB J 2013 Apr 9;27(4):1721-32. Epub 2013 Jan 9.

Leiden University Medical Center, Department of Molecular Cell Biology, Laboratory of Neurophysiology, Bldg. 2, Room T5-32, Einthovenweg 20, PO Box 9600, 2300 RC Leiden, the Netherlands.

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April 2013

META060 protects against diet-induced obesity and insulin resistance in a high-fat-diet fed mouse.

Nutrition 2013 Jan 15;29(1):276-83. Epub 2012 Sep 15.

Department of General Internal Medicine, Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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January 2013

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Authors:
Zari Dastani Marie-France Hivert Nicholas Timpson John R B Perry Xin Yuan Robert A Scott Peter Henneman Iris M Heid Jorge R Kizer Leo-Pekka Lyytikäinen Christian Fuchsberger Toshiko Tanaka Andrew P Morris Kerrin Small Aaron Isaacs Marian Beekman Stefan Coassin Kurt Lohman Lu Qi Stavroula Kanoni James S Pankow Hae-Won Uh Ying Wu Aurelian Bidulescu Laura J Rasmussen-Torvik Celia M T Greenwood Martin Ladouceur Jonna Grimsby Alisa K Manning Ching-Ti Liu Jaspal Kooner Vincent E Mooser Peter Vollenweider Karen A Kapur John Chambers Nicholas J Wareham Claudia Langenberg Rune Frants Ko Willems-Vandijk Ben A Oostra Sara M Willems Claudia Lamina Thomas W Winkler Bruce M Psaty Russell P Tracy Jennifer Brody Ida Chen Jorma Viikari Mika Kähönen Peter P Pramstaller David M Evans Beate St Pourcain Naveed Sattar Andrew R Wood Stefania Bandinelli Olga D Carlson Josephine M Egan Stefan Böhringer Diana van Heemst Lyudmyla Kedenko Kati Kristiansson Marja-Liisa Nuotio Britt-Marie Loo Tamara Harris Melissa Garcia Alka Kanaya Margot Haun Norman Klopp H-Erich Wichmann Panos Deloukas Efi Katsareli David J Couper Bruce B Duncan Margreet Kloppenburg Linda S Adair Judith B Borja James G Wilson Solomon Musani Xiuqing Guo Toby Johnson Robert Semple Tanya M Teslovich Matthew A Allison Susan Redline Sarah G Buxbaum Karen L Mohlke Ingrid Meulenbelt Christie M Ballantyne George V Dedoussis Frank B Hu Yongmei Liu Bernhard Paulweber Timothy D Spector P Eline Slagboom Luigi Ferrucci Antti Jula Markus Perola Olli Raitakari Jose C Florez Veikko Salomaa Johan G Eriksson Timothy M Frayling Andrew A Hicks Terho Lehtimäki George Davey Smith David S Siscovick Florian Kronenberg Cornelia van Duijn Ruth J F Loos Dawn M Waterworth James B Meigs Josee Dupuis J Brent Richards Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Oliver M Hofmann Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Andrew D Morris Colin N A Palmer Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Oluf Pedersen Inês Barroso Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Paul Elliott Denis Rybin Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Taina Lajunen Alex Doney Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurðsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper Manuel Serrano-Ríos Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter Brenda W J H Penninx Dorret I Boomsma Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Leena Peltonen Vincent Mooser Robert Sladek Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Daniel I Chasman Christopher T Johansen Sigrid W Fouchier Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Mary F Feitosa Marju Orho-Melander Olle Melander Xiaohui Li Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Andreas Ziegler Weihua Zhang Robert Y L Zee John B Whitfield John R Thompson Ida Surakka Tim D Spector Johannes H Smit Juha Sinisalo James Scott Juha Saharinen Chiara Sabatti Lynda M Rose Robert Roberts Mark Rieder Alex N Parker Guillaume Pare Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Gavin Lucas Robert Luben Marja-Liisa Lokki Guillaume Lettre Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Inke R König Kay-Tee Khaw Lee M Kaplan Åsa Johansson A Cecile J W Janssens Wilmar Igl G Kees Hovingh Christian Hengstenberg Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Leif C Groop Elena Gonzalez Nelson B Freimer Jeanette Erdmann Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Ulf de Faire Gabriel Crawford Yii-der I Chen Mark J Caulfield S Matthijs Boekholdt Themistocles L Assimes Thomas Quertermous Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Herman A Taylor Stacey B Gabriel Hilma Holm Vilmundur Gudnason Ronald M Krauss Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt David P Strachan Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Sekar Kathiresan

PLoS Genet 2012 29;8(3):e1002607. Epub 2012 Mar 29.

Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.

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September 2012

A genome-wide association search for type 2 diabetes genes in African Americans.

Authors:
Nicholette D Palmer Caitrin W McDonough Pamela J Hicks Bong H Roh Maria R Wing S Sandy An Jessica M Hester Jessica N Cooke Meredith A Bostrom Megan E Rudock Matthew E Talbert Joshua P Lewis Assiamira Ferrara Lingyi Lu Julie T Ziegler Michele M Sale Jasmin Divers Daniel Shriner Adebowale Adeyemo Charles N Rotimi Maggie C Y Ng Carl D Langefeld Barry I Freedman Donald W Bowden Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Andrew P Morris Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Claudia Langenberg Oliver M Hofmann Josée Dupuis Lu Qi Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis David J Couper Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Norman Klopp Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne John R B Perry Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Karen L Mohlke Andrew D Morris Colin N A Palmer Peter P Pramstaller Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Nicholas J Wareham Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Frank B Hu James B Meigs James S Pankow Oluf Pedersen H-Erich Wichmann Inês Barroso Jose C Florez Timothy M Frayling Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Toby Johnson Paul Elliott Denis Rybin Peter Henneman Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Josephine M Egan Taina Lajunen Alex Doney Stavroula Kanoni Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Rune Frants Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg Andrew A Hicks David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Antti Jula Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino Alisa K Manning María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Ben A Oostra Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Markus Perola Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Bruce M Psaty Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Toshiko Tanaka Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Ruth J F Loos Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Veikko Salomaa George Davey Smith Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper George V Dedoussis Manuel Serrano-Ríos Lars Lind Lyle J Palmer Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter David S Siscovick Brenda W J H Penninx Dorret I Boomsma Panos Deloukas Timothy D Spector Luigi Ferrucci Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Dawn M Waterworth Peter Vollenweider Leena Peltonen Vincent Mooser Robert Sladek

PLoS One 2012 4;7(1):e29202. Epub 2012 Jan 4.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://dx.plos.org/10.1371/journal.pone.0029202
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251563PMC
May 2012

Gender-dependent effects of high-fat lard diet on cardiac function in C57Bl/6J mice.

Appl Physiol Nutr Metab 2012 Apr 1;37(2):214-24. Epub 2012 Mar 1.

Department of General Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.

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April 2012