Knut Krohn

Knut Krohn

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Knut Krohn

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Author Correction: Identification of stably expressed housekeeping miRNAs in endothelial cells and macrophages in an inflammatory setting.

Sci Rep 2019 Oct 3;9(1):14466. Epub 2019 Oct 3.

Clinic for Anaesthesiology and Operative Intensive Care, University Hospital Halle (Saale), Halle, Saale, Germany.

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http://dx.doi.org/10.1038/s41598-019-51008-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775137PMC
October 2019

Identification of stably expressed housekeeping miRNAs in endothelial cells and macrophages in an inflammatory setting.

Sci Rep 2019 Sep 4;9(1):12786. Epub 2019 Sep 4.

Clinic for Anaesthesiology and Operative Intensive Care, University Hospital Halle (Saale), Halle, Saale, Germany.

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http://dx.doi.org/10.1038/s41598-019-49241-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726651PMC
September 2019

Gene expression profiling in adipose tissue of Sprague Dawley rats identifies olfactory receptor 984 as a potential obesity treatment target.

Biochem Biophys Res Commun 2018 11 5;505(3):801-806. Epub 2018 Oct 5.

Department of Medicine, University of Leipzig, 04103, Leipzig, Germany; Leipzig University Medical Center, IFB AdiposityDiseases, University of Leipzig, 04103, Leipzig, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183207
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http://dx.doi.org/10.1016/j.bbrc.2018.09.137DOI Listing
November 2018

Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier.

Atherosclerosis 2017 10 4;265:197-206. Epub 2017 Sep 4.

Institute of Laboratory Medicine, Ludwig Maximilians University Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.08.030DOI Listing
October 2017

RNA-Seq Identifies Circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke.

Circ Res 2017 Sep 19;121(8):970-980. Epub 2017 Jul 19.

From the Institute for Stroke and Dementia Research, Klinikum der Universität München (S.T., M.P., R.M., N.S., M.D., V.K., I.S., J.B., A.L., N.P., M.D.), Graduate School of Systemic Neurosciences (S.T.), Institute of Laboratory Medicine, Klinikum der Universität München (B.H.N., D.T., L.M.H.), Department of Neurology, Klinikum der Universität München (M.K.), and Department of Neuroradiology, Klinikum der Universität München (F.D.), Ludwig-Maximilians-Universität LMU, Germany; Munich Cluster for Systems Neurology (SyNergy), Germany (S.T., A.L., N.P., M.D.); and Interdisciplinary Center for Clinical Research (IZKF), University of Leipzig, Germany (K.K.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311572DOI Listing
September 2017

Two-miRNA classifiers differentiate mutation-negative follicular thyroid carcinomas and follicular thyroid adenomas in fine needle aspirations with high specificity.

Endocrine 2016 Nov 29;54(2):440-447. Epub 2016 Jul 29.

Department of Oncology and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1007/s12020-016-1021-7DOI Listing
November 2016

The Y3** ncRNA promotes the 3' end processing of histone mRNAs.

Genes Dev 2015 Oct;29(19):1998-2003

Institute of Molecular Medicine, Martin-Luther-University Halle-Wittenberg, Saxony-Anhalt 06120, Germany;

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http://dx.doi.org/10.1101/gad.266486.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604341PMC
October 2015

Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.

PLoS Genet 2015 Sep 24;11(9):e1005510. Epub 2015 Sep 24.

LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig Germany; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1371/journal.pgen.1005510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581711PMC
September 2015

A two miRNA classifier differentiates follicular thyroid carcinomas from follicular thyroid adenomas.

Mol Cell Endocrinol 2015 Jan 26;399:43-9. Epub 2014 Sep 26.

Division of Endocrinology and Nephrology, University of Leipzig, Liebigstr. 21, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.mce.2014.09.017DOI Listing
January 2015

Somatic mutations in 33 benign and malignant hot thyroid nodules in children and adolescents.

Mol Cell Endocrinol 2014 Aug 8;393(1-2):39-45. Epub 2014 Jun 8.

Division of Endocrinology and Nephrology, University of Leipzig, Liebigstr. 20, D-04103 Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2014.05.023DOI Listing
August 2014

Rapid identification of regulatory microRNAs by miTRAP (miRNA trapping by RNA in vitro affinity purification).

Nucleic Acids Res 2014 Apr 7;42(8):e66. Epub 2014 Feb 7.

Division of Molecular Cell Biology, Institute of Molecular Medicine, Martin Luther University Halle-Wittenberg, Heinrich-Damerow-Strasse 1, 06120 Halle, Germany and Interdisciplinary Center for Clinical Research, University Leipzig, Liebigstrasse 21, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1093/nar/gku127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005655PMC
April 2014

Analysis options for high-throughput sequencing in miRNA expression profiling.

BMC Res Notes 2014 Mar 13;7:144. Epub 2014 Mar 13.

Interdisciplinary Center for Clinical Research (IZKF), University of Leipzig, Liebigstr, 21, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1186/1756-0500-7-144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007773PMC
March 2014

Glycerophosphoglycerol, Beta-alanine, and pantothenic Acid as metabolic companions of glycolytic activity and cell migration in breast cancer cell lines.

Metabolites 2013 Nov 27;3(4):1084-101. Epub 2013 Nov 27.

Faculty of Chemistry and Mineralogy, Institute of Analytical Chemistry, University of Leipzig, Linnéstr 3, 04103 Leipzig, Germany.

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http://dx.doi.org/10.3390/metabo3041084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937838PMC
November 2013

Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid.

Int J Biochem Cell Biol 2012 Feb 3;44(2):290-301. Epub 2011 Nov 3.

Clinic for Endocrinology and Nephrology, University of Leipzig, Liebigstr. 20, D-04413 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.biocel.2011.10.024DOI Listing
February 2012

Effect of iodine on early stage thyroid autonomy.

Genomics 2011 Feb 28;97(2):94-100. Epub 2010 Oct 28.

Department of Internal Medicine, Division of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1016/j.ygeno.2010.10.007DOI Listing
February 2011

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.

Authors:
Nicole Soranzo Serena Sanna Eleanor Wheeler Christian Gieger Dörte Radke Josée Dupuis Nabila Bouatia-Naji Claudia Langenberg Inga Prokopenko Elliot Stolerman Manjinder S Sandhu Matthew M Heeney Joseph M Devaney Muredach P Reilly Sally L Ricketts Alexandre F R Stewart Benjamin F Voight Christina Willenborg Benjamin Wright David Altshuler Dan Arking Beverley Balkau Daniel Barnes Eric Boerwinkle Bernhard Böhm Amélie Bonnefond Lori L Bonnycastle Dorret I Boomsma Stefan R Bornstein Yvonne Böttcher Suzannah Bumpstead Mary Susan Burnett-Miller Harry Campbell Antonio Cao John Chambers Robert Clark Francis S Collins Josef Coresh Eco J C de Geus Mariano Dei Panos Deloukas Angela Döring Josephine M Egan Roberto Elosua Luigi Ferrucci Nita Forouhi Caroline S Fox Christopher Franklin Maria Grazia Franzosi Sophie Gallina Anuj Goel Jürgen Graessler Harald Grallert Andreas Greinacher David Hadley Alistair Hall Anders Hamsten Caroline Hayward Simon Heath Christian Herder Georg Homuth Jouke-Jan Hottenga Rachel Hunter-Merrill Thomas Illig Anne U Jackson Antti Jula Marcus Kleber Christopher W Knouff Augustine Kong Jaspal Kooner Anna Köttgen Peter Kovacs Knut Krohn Brigitte Kühnel Johanna Kuusisto Markku Laakso Mark Lathrop Cécile Lecoeur Man Li Mingyao Li Ruth J F Loos Jian'an Luan Valeriya Lyssenko Reedik Mägi Patrik K E Magnusson Anders Mälarstig Massimo Mangino María Teresa Martínez-Larrad Winfried März Wendy L McArdle Ruth McPherson Christa Meisinger Thomas Meitinger Olle Melander Karen L Mohlke Vincent E Mooser Mario A Morken Narisu Narisu David M Nathan Matthias Nauck Chris O'Donnell Konrad Oexle Nazario Olla James S Pankow Felicity Payne John F Peden Nancy L Pedersen Leena Peltonen Markus Perola Ozren Polasek Eleonora Porcu Daniel J Rader Wolfgang Rathmann Samuli Ripatti Ghislain Rocheleau Michael Roden Igor Rudan Veikko Salomaa Richa Saxena David Schlessinger Heribert Schunkert Peter Schwarz Udo Seedorf Elizabeth Selvin Manuel Serrano-Ríos Peter Shrader Angela Silveira David Siscovick Kjioung Song Timothy D Spector Kari Stefansson Valgerdur Steinthorsdottir David P Strachan Rona Strawbridge Michael Stumvoll Ida Surakka Amy J Swift Toshiko Tanaka Alexander Teumer Gudmar Thorleifsson Unnur Thorsteinsdottir Anke Tönjes Gianluca Usala Veronique Vitart Henry Völzke Henri Wallaschofski Dawn M Waterworth Hugh Watkins H-Erich Wichmann Sarah H Wild Gonneke Willemsen Gordon H Williams James F Wilson Juliane Winkelmann Alan F Wright Carina Zabena Jing Hua Zhao Stephen E Epstein Jeanette Erdmann Hakon H Hakonarson Sekar Kathiresan Kay-Tee Khaw Robert Roberts Nilesh J Samani Mark D Fleming Robert Sladek Gonçalo Abecasis Michael Boehnke Philippe Froguel Leif Groop Mark I McCarthy W H Linda Kao Jose C Florez Manuela Uda Nicholas J Wareham Inês Barroso James B Meigs

Diabetes 2010 Dec 21;59(12):3229-39. Epub 2010 Sep 21.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.

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http://dx.doi.org/10.2337/db10-0502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992787PMC
December 2010

Washing scaling of GeneChip microarray expression.

BMC Bioinformatics 2010 May 28;11:291. Epub 2010 May 28.

Interdisciplinary Centre for Bioinformatics; Universität Leipzig, D-4107 Leipzig, Haertelstr 16-18, Germany.

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http://dx.doi.org/10.1186/1471-2105-11-291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901370PMC
May 2010

Calcium signaling of thyrocytes is modulated by TSH through calcium binding protein expression.

Biochim Biophys Acta 2010 Mar 18;1803(3):352-60. Epub 2010 Jan 18.

III. Medical Department, Faculty of Medicine, University of Leipzig, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.bbamcr.2010.01.007DOI Listing
March 2010

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

Authors:
Richa Saxena Marie-France Hivert Claudia Langenberg Toshiko Tanaka James S Pankow Peter Vollenweider Valeriya Lyssenko Nabila Bouatia-Naji Josée Dupuis Anne U Jackson W H Linda Kao Man Li Nicole L Glazer Alisa K Manning Jian'an Luan Heather M Stringham Inga Prokopenko Toby Johnson Niels Grarup Trine W Boesgaard Cécile Lecoeur Peter Shrader Jeffrey O'Connell Erik Ingelsson David J Couper Kenneth Rice Kijoung Song Camilla H Andreasen Christian Dina Anna Köttgen Olivier Le Bacquer François Pattou Jalal Taneera Valgerdur Steinthorsdottir Denis Rybin Kristin Ardlie Michael Sampson Lu Qi Mandy van Hoek Michael N Weedon Yurii S Aulchenko Benjamin F Voight Harald Grallert Beverley Balkau Richard N Bergman Suzette J Bielinski Amelie Bonnefond Lori L Bonnycastle Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Thomas A Buchanan Suzannah J Bumpstead Christine Cavalcanti-Proença Guillaume Charpentier Yii-Der Ida Chen Peter S Chines Francis S Collins Marilyn Cornelis Gabriel J Crawford Jerome Delplanque Alex Doney Josephine M Egan Michael R Erdos Mathieu Firmann Nita G Forouhi Caroline S Fox Mark O Goodarzi Jürgen Graessler Aroon Hingorani Bo Isomaa Torben Jørgensen Mika Kivimaki Peter Kovacs Knut Krohn Meena Kumari Torsten Lauritzen Claire Lévy-Marchal Vladimir Mayor Jarred B McAteer David Meyre Braxton D Mitchell Karen L Mohlke Mario A Morken Narisu Narisu Colin N A Palmer Ruth Pakyz Laura Pascoe Felicity Payne Daniel Pearson Wolfgang Rathmann Annelli Sandbaek Avan Aihie Sayer Laura J Scott Stephen J Sharp Eric Sijbrands Andrew Singleton David S Siscovick Nicholas L Smith Thomas Sparsø Amy J Swift Holly Syddall Gudmar Thorleifsson Anke Tönjes Tiinamaija Tuomi Jaakko Tuomilehto Timo T Valle Gérard Waeber Andrew Walley Dawn M Waterworth Eleftheria Zeggini Jing Hua Zhao Thomas Illig H Erich Wichmann James F Wilson Cornelia van Duijn Frank B Hu Andrew D Morris Timothy M Frayling Andrew T Hattersley Unnur Thorsteinsdottir Kari Stefansson Peter Nilsson Ann-Christine Syvänen Alan R Shuldiner Mark Walker Stefan R Bornstein Peter Schwarz Gordon H Williams David M Nathan Johanna Kuusisto Markku Laakso Cyrus Cooper Michael Marmot Luigi Ferrucci Vincent Mooser Michael Stumvoll Ruth J F Loos David Altshuler Bruce M Psaty Jerome I Rotter Eric Boerwinkle Torben Hansen Oluf Pedersen Jose C Florez Mark I McCarthy Michael Boehnke Inês Barroso Robert Sladek Philippe Froguel James B Meigs Leif Groop Nicholas J Wareham Richard M Watanabe

Nat Genet 2010 Feb 17;42(2):142-8. Epub 2010 Jan 17.

Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922003PMC
February 2010

Perspectives for improved and more accurate classification of thyroid epithelial tumors.

J Clin Endocrinol Metab 2008 Sep 1;93(9):3286-94. Epub 2008 Jul 1.

Third Medical Department, University of Leipzig, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/jc.2008-0201DOI Listing
September 2008

"Hook"-calibration of GeneChip-microarrays: chip characteristics and expression measures.

Algorithms Mol Biol 2008 Aug 29;3:11. Epub 2008 Aug 29.

Interdisciplinary Centre for Bioinformatics, University of Leipzig, D-04107 Leipzig, Germany.

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http://dx.doi.org/10.1186/1748-7188-3-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2543012PMC
August 2008

Mechanisms of disease: hydrogen peroxide, DNA damage and mutagenesis in the development of thyroid tumors.

Nat Clin Pract Endocrinol Metab 2007 Oct;3(10):713-20

Interdisciplinary Center for Clinical Research, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1038/ncpendmet0621DOI Listing
October 2007

Perspectives and limitations of microarray-based gene expression profiling of thyroid tumors.

Endocr Rev 2007 May 12;28(3):322-38. Epub 2007 Mar 12.

III. Medical Department, University of Leipzig, Ph.-Rosenthal-Str. 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/er.2006-0047DOI Listing
May 2007

Meta- and reanalysis of gene expression profiles of hot and cold thyroid nodules and papillary thyroid carcinoma for gene groups.

J Clin Endocrinol Metab 2006 May 11;91(5):1934-42. Epub 2006 Jan 11.

III. Medical Department, University of Leipzig, Philipp-Rosenthal-Strasse 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/jc.2005-1620DOI Listing
May 2006

Comparison of differential gene expression of hot and cold thyroid nodules with primary epithelial cell culture models by investigation of co-regulated gene sets.

Biochim Biophys Acta 2006 Mar 4;1763(3):263-71. Epub 2006 Jan 4.

III. Medical Department, University of Leipzig, Ph.-Rosenthal-Str. 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1016/j.bbamcr.2005.12.001DOI Listing
March 2006

Sialylation of human thyrotropin receptor improves and prolongs its cell-surface expression.

Mol Pharmacol 2005 Oct 13;68(4):1106-13. Epub 2005 Jul 13.

Medical Department, University of Leipzig, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1124/mol.105.012906DOI Listing
October 2005

Molecular pathogenesis of euthyroid and toxic multinodular goiter.

Endocr Rev 2005 Jun 22;26(4):504-24. Epub 2004 Dec 22.

Universität Leipzig, Zentrum für Innere Medizin, Medizinische Klinik und Poliklinik III, Ph.-Rosenthal-Strasse 27, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/er.2004-0005DOI Listing
June 2005

Regulation of adiponectin receptor R1 and R2 gene expression in adipocytes of C57BL/6 mice.

Biochem Biophys Res Commun 2005 Apr;329(3):1127-32

Junior Research Group N03, IZKF Leipzig, University of Leipzig, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0500335
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http://dx.doi.org/10.1016/j.bbrc.2005.02.081DOI Listing
April 2005

Gene expression analysis reveals evidence for increased expression of cell cycle-associated genes and Gq-protein-protein kinase C signaling in cold thyroid nodules.

J Clin Endocrinol Metab 2005 Feb 2;90(2):1163-70. Epub 2004 Nov 2.

III. Medical Department, University of Leipzig, Philipp-Rosenthal-Strasse 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1210/jc.2004-1242DOI Listing
February 2005

BRAF mutations are not an alternative explanation for the molecular etiology of ras-mutation negative cold thyroid nodules.

Thyroid 2004 May;14(5):359-61

Medical Department, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1089/105072504774193186DOI Listing
May 2004

Gene expression analysis reveals evidence for inactivation of the TGF-beta signaling cascade in autonomously functioning thyroid nodules.

Oncogene 2004 Jan;23(3):795-804

III Medical Department, University of Leipzig, Ph-Rosenthal-Str 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1038/sj.onc.1207186DOI Listing
January 2004

Cold thyroid nodules show a marked increase in proliferation markers.

Thyroid 2003 Jun;13(6):569-75

III Medical Department, and Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1089/105072503322238836DOI Listing
June 2003

Somatic mutations in thyroid nodular disease.

Mol Genet Metab 2002 Mar;75(3):202-8

III. Medical Department, University of Leipzig, Philipp-Rosenthal-Strasse 27, D-04103 Leipzig, Germany.

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http://dx.doi.org/10.1006/mgme.2001.3290DOI Listing
March 2002