Klaus-Peter Lesch

Klaus-Peter Lesch

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Klaus-Peter Lesch

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Repeated methamphetamine treatment increases spine density in the nucleus accumbens of serotonin transporter knockout mice.

Neuropsychopharmacol Rep 2019 Jun 4;39(2):130-133. Epub 2019 Feb 4.

Department of Biological Psychiatry, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1002/npr2.12049DOI Listing
June 2019

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish.

Biol Open 2019 Jun 5;8(6). Epub 2019 Jun 5.

Department of Physiological Chemistry, Biocenter, Am Hubland, University of Würzburg, Germany

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http://dx.doi.org/10.1242/bio.040683DOI Listing
June 2019

KCNJ6 variants modulate reward-related brain processes and impact executive functions in attention-deficit/hyperactivity disorder.

Am J Med Genet B Neuropsychiatr Genet 2019 May 17. Epub 2019 May 17.

Division of Molecular Psychiatry, ADHD Clinical Research Unit, Laboratory of Translational Neuroscience, Center of Mental Health, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1002/ajmg.b.32734DOI Listing
May 2019

Relapse of drunk driving and association with traffic accidents, alcohol-related problems and biomarkers of impulsivity.

Acta Neuropsychiatr 2019 Apr 26;31(2):84-92. Epub 2018 Nov 26.

1Division of Neuropsychopharmacology, Department of Psychology,University of Tartu,Estonia.

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http://dx.doi.org/10.1017/neu.2018.30DOI Listing
April 2019

Brain Imaging of the Cortex in ADHD: A Coordinated Analysis of Large-Scale Clinical and Population-Based Samples.

Authors:
Martine Hoogman Ryan Muetzel Joao P Guimaraes Elena Shumskaya Maarten Mennes Marcel P Zwiers Neda Jahanshad Gustavo Sudre Thomas Wolfers Eric A Earl Juan Carlos Soliva Vila Yolanda Vives-Gilabert Sabin Khadka Stephanie E Novotny Catharina A Hartman Dirk J Heslenfeld Lizanne J S Schweren Sara Ambrosino Bob Oranje Patrick de Zeeuw Tiffany M Chaim-Avancini Pedro G P Rosa Marcus V Zanetti Charles B Malpas Gregor Kohls Georg G von Polier Jochen Seitz Joseph Biederman Alysa E Doyle Anders M Dale Theo G M van Erp Jeffery N Epstein Terry L Jernigan Ramona Baur-Streubel Georg C Ziegler Kathrin C Zierhut Anouk Schrantee Marie F Høvik Astri J Lundervold Clare Kelly Hazel McCarthy Norbert Skokauskas Ruth L O'Gorman Tuura Anna Calvo Sara Lera-Miguel Rosa Nicolau Kaylita C Chantiluke Anastasia Christakou Alasdair Vance Mara Cercignani Matt C Gabel Philip Asherson Sarah Baumeister Daniel Brandeis Sarah Hohmann Ivanei E Bramati Fernanda Tovar-Moll Andreas J Fallgatter Bernd Kardatzki Lena Schwarz Anatoly Anikin Alexandr Baranov Tinatin Gogberashvili Dmitry Kapilushniy Anastasia Solovieva Hanan El Marroun Tonya White Georgii Karkashadze Leyla Namazova-Baranova Thomas Ethofer Paulo Mattos Tobias Banaschewski David Coghill Kerstin J Plessen Jonna Kuntsi Mitul A Mehta Yannis Paloyelis Neil A Harrison Mark A Bellgrove Tim J Silk Ana I Cubillo Katya Rubia Luisa Lazaro Silvia Brem Susanne Walitza Thomas Frodl Mariam Zentis Francisco X Castellanos Yuliya N Yoncheva Jan Haavik Liesbeth Reneman Annette Conzelmann Klaus-Peter Lesch Paul Pauli Andreas Reif Leanne Tamm Kerstin Konrad Eileen Oberwelland Weiss Geraldo F Busatto Mario R Louza Sarah Durston Pieter J Hoekstra Jaap Oosterlaan Michael C Stevens J Antoni Ramos-Quiroga Oscar Vilarroya Damien A Fair Joel T Nigg Paul M Thompson Jan K Buitelaar Stephen V Faraone Philip Shaw Henning Tiemeier Janita Bralten Barbara Franke

Am J Psychiatry 2019 Apr 24:appiajp201918091033. Epub 2019 Apr 24.

The Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands (Hoogman, Guimaraes, Shumskaya, Wolfers, Bralten, Franke); the Donders Institute for Brain, Cognition, and Behavior, Radboud University, Nijmegen, the Netherlands (Hoogman, Shumskaya, Mennes, Wolfers, Buitelaar, Bralten, Franke); the Department of Child and Adolescent Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands (Muetzel, El Marroun, White, Tiemeier); the Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands (Muetzel); the Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, the Netherlands (Guimaraes, Zwiers, Buitelaar); the Imaging Genetics Center, Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, Marina del Rey, Calif. (Jahanshad, Thompson); National Human Genome Research Institute, Bethesda, Md. (Sudre, Shaw); the Department of Behavioral Neuroscience, Oregon Health and Science University, Portland (Earl, Fair, Nigg); the Department of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Cerdanyola del Vallès, Spain (Soliva Vila, Ramos-Quiroga, Vilarroya); Instituto ITACA, Polytechnic University of Valencia, Valencia, Spain (Vives-Gilabert); the Olin Neuropsychiatry Research Center, Hartford Hospital, Hartford, Conn. (Khadka, Novotny, Stevens); University of Groningen, University Medical Center Groningen (UMCG), Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Groningen, the Netherlands (Hartman, Schweren); Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam (Heslenfeld); the Department of Child and Adolescent Psychiatry, University of Groningen, University Medical Center Groningen, the Netherlands (Hoekstra); NICHE Lab, Department of Psychiatry, UMC Utrecht Brain Center, Utrecht, the Netherlands (Ambrosino, Oranje, de Zeeuw, Durston); Laboratory of Psychiatric Neuroimaging (LIM-21), Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil (Chaim-Avancini, Rosa, Zanetti, Busatto); the Center for Interdisciplinary Research on Applied Neurosciences (NAPNA), University of São Paulo, São Paulo, Brazil (Chaim-Avancini, Rosa, Zanetti, Busatto); the Developmental Imaging Group, Murdoch Children's Research Institute, Melbourne, Australia (Malpas); the Clinical Outcomes Research Unit (CORe), Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia (Malpas); the Melbourne School of Psychological Sciences, University of Melbourne, Melbourne, Australia (Malpas); the Child Neuropsychology Section, University Hospital RWTH Aachen, Aachen, Germany (Kohls, Konrad; Child and Adolescent Psychiatry, University Hospital RWTH Aachen, Aachen, Germany (Polier, Seitz); Institute of Neuroscience and Medicine-Brain and Behavior (INM-7), Research Center Jülich, Jülich, Germany (Polier); the Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston (Biederman); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston (Biederman, Doyle); the Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (Doyle); the Departments of Neurosciences, Radiology, and Psychiatry and the Center for Multimodal Imaging and Genetics, University of California San Diego (Dale); the Clinical and Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine, Irvine (van Erp); the Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati (Epstein, Tamm); the Center for Human Development, University of California San Diego, San Diego (Jernigan); the Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany (Ziegler, Lesch); the Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam (Schrantee, Reneman); the Department of Clinical Medicine, University of Bergen, Bergen, Norway (Høvik); the Division of Psychiatry, Haukeland University Hospital, Bergen, Norway (Høvik, Haavik); the Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway (Lundervold); the K.G. Jebsen Center for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, Bergen, Norway (Lundervold, Haavik); the School of Psychology and the Department of Psychiatry, School of Medicine, and the Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland (Kelly); the Department of Child and Adolescent Psychiatry, NYU Langone Medical Center, New York (Kelly, Castellanos, Yoncheva); the Department of Psychiatry, Trinity College Dublin, Ireland (McCarthy, Skokauskas, Frodl); the Centre for Advanced Medical Imaging, St. James's Hospital, Dublin, Ireland (McCarthy); the Center for Child and Adolescent Mental Health, NTNU, Norway, Norwegian University of Science and Technology, Norway (Skokauskas); the Center for MR Research, University Children's Hospital, and the Zurich Center for Integrative Human Physiology, Zurich (O'Gorman Tuura); Magnetic Resonance Image Core Facility, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain (Calvo, Lazaro); the Department of Child and Adolescent Psychiatry and Psychology, Institute of Neurosciences, Hospital Clinic, Barcelona, Spain (Lera-Miguel, Nicolau, Lazaro); the Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King's College London (Chantiluke, Christakou, Cubillo, Rubia); the School of Psychology and Clinical Language Sciences, Centre for Integrative Neuroscience and Neurodynamics, University of Reading, Reading, U.K. (Christakou); the Department of Paediatrics, University of Melbourne, Australia (Vance, Coghill, Silk); the Department of Neuroscience, Brighton and Sussex Medical School, Falmer, Brighton, U.K. (Cercignani, Gabel, Harrison); the Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London (Asherson, Kuntsi); the Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany (Baumeister, Brandeis, Hohmann, Banaschewski); the Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric Hospital, University of Zurich, Zurich (Brandeis, Brem, Walitza); the Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich (Brandeis, Brem, Walitza); the D'Or Institute for Research and Education, Rio de Janeiro (Bramati, Tovar-Moll, Mattos); the Morphological Sciences Program, Federal University of Rio de Janeiro, Rio de Janeiro (Tovar-Moll); the Department of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany (Fallgatter, Schwarz, Ethofer); LEAD Graduate School, University of Tübingen, Germany (Fallgatter); the Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany (Kardatzki, Ethofer); the National Medical Research Center for Children's Health, Department of Magnetic Resonance Imaging and Densitometry, Moscow (Anikin); the National Medical Research Center for Children's Health, Moscow (Baranov, Solovieva); Russian National Research Medical University, Ministry of Health and Social Development of the Russian Federation, Central Clinical Hospital MSHE, Moscow (Namazova-Baranova); the National Medical Research Center for Children's Health, Laboratory of Neurology and Cognitive Health, Moscow (Gogberashvili, Karkashadze); the National Medical Research Center for Children's Health, Department of Information Technologies, Moscow (Kapilushniy); the Department of Pediatrics, Erasmus MC-Sophia, Rotterdam, the Netherlands (El Marroun); the Department of Psychology, Education, and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands (El Marroun); the Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands (White); Federal University of Rio de Janeiro, Rio de Janeiro (Mattos); the Department of Psychiatry, University of Melbourne, Melbourne, Australia (Coghill); the Murdoch Children's Research Institute, Melbourne, Australia (Coghill, Silk); the Division of Neuroscience, University of Dundee, Dundee, U.K. (Coghill); the Child and Adolescent Mental Health Center, Capital Region Copenhagen (Plessen); the Division of Child and Adolescent Psychiatry, Department of Psychiatry, University Hospital Lausanne, Switzerland (Plessen); the Department of Neuroimaging, Institute of Psychiatry, Psychology, and Neuroscience, King's College London (Mehta, Paloyelis); Sussex Partnership NHS Foundation Trust, Swandean, East Sussex, U.K. (Harrison); the Monash Institute for Cognitive and Clinical Neurosciences (MICCN) and the School of Psychological Sciences, Monash University, Melbourne, Australia (Bellgrove); Deakin University, School of Psychology, Geelong, Australia (Silk); the Department of Medicine, University of Barcelona, Barcelona, Spain (Lazaro); the Department of Psychiatry and Psychotherapy, Otto von Guericke University Magdeburg, Germany (Frodl); the German Center for Neurodegenerative Diseases (DZNE), Germany (Frodl); Bezirksklinikum Regensburg, Germany (Zentis); the Nathan Kline Institute for Psychiatric Research, Orangeburg, N.Y. (Castellanos); the Brain Imaging Center, Amsterdam University Medical Centers, Amsterdam (Reneman); the Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Tübingen, Germany (Conzelmann); the Department of Psychology, Biological Psychology, Clinical Psychology, and Psychotherapy, University of Würzburg, Würzburg, Germany (Conzelmann, Pauli, Baur-Streubel, Zierhut); the Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, Moscow (Lesch); the Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, the Netherlands (Lesch); the Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany (Reif); JARA Institute Molecular Neuroscience and Neuroimaging (INM-11), Institute for Neuroscience and Medicine, Research Center Jülich, Germany (Konrad); Translational Neuroscience, Child and Adolescent Psychiatry, University Hospital RWTH Aachen, Aachen, Germany (Oberwelland Weiss); Cognitive Neuroscience (INM-3), Institute for Neuroscience and Medicine, Research Center Jülich, Germany (Oberwelland Weiss); the Department of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil (Busatto, Louza); the Clinical Neuropsychology Section, Vrije Universiteit Amsterdam, Amsterdam (Oosterlaan); Emma Children's Hospital Amsterdam Medical Center, Amsterdam (Oosterlaan); the Department of Pediatrics, VU Medical Center, Amsterdam (Oosterlaan); the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Stevens); the Department of Psychiatry, Vall d'Hebron University Hospital, Barcelona, Spain (Ramos-Quiroga); Biomedical Network Research Center on Mental Health (CIBERSAM), Barcelona, Spain (Lazaro, Ramos-Quiroga); Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain (Vilarroya); the Department of Psychiatry, Oregon Health and Science University, Portland (Fair, Nigg); Karakter Child and Adolescent Psychiatry University Center, Nijmegen, the Netherlands (Buitelaar); Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York (Faraone); NIHM, Bethesda, Md. (Shaw); the Department of Social and Behavioral Science, Harvard T.H. Chan School of Public Health, Boston (Tiemeier).

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http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2019.18
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http://dx.doi.org/10.1176/appi.ajp.2019.18091033DOI Listing
April 2019

Early-life stress impairs developmental programming in Cadherin 13 (CDH13)-deficient mice.

Prog Neuropsychopharmacol Biol Psychiatry 2019 03 28;89:158-168. Epub 2018 Aug 28.

Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2018.08.010DOI Listing
March 2019

Editorial: Can dysregulated myelination be linked to ADHD pathogenesis and persistence?

J Child Psychol Psychiatry 2019 Mar;60(3):229-231

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http://dx.doi.org/10.1111/jcpp.13031DOI Listing
March 2019

Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder.

Atten Defic Hyperact Disord 2019 Mar 29;11(1):107-111. Epub 2019 Mar 29.

Department for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Tübingen, Tübingen, Germany.

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http://link.springer.com/10.1007/s12402-019-00286-8
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http://dx.doi.org/10.1007/s12402-019-00286-8DOI Listing
March 2019

Brain serotonin deficiency affects female aggression.

Sci Rep 2019 Feb 4;9(1):1366. Epub 2019 Feb 4.

Department of Behavioural Biology, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1038/s41598-018-37613-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361930PMC
February 2019

Improved cognition, mild anxiety-like behavior and decreased motor performance in pyridoxal phosphatase-deficient mice.

Biochim Biophys Acta Mol Basis Dis 2019 Jan 16;1865(1):193-205. Epub 2018 Aug 16.

Institute of Pharmacology and Toxicology, University of Würzburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439183030
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http://dx.doi.org/10.1016/j.bbadis.2018.08.018DOI Listing
January 2019

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.

Nat Genet 2019 01 26;51(1):63-75. Epub 2018 Nov 26.

Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/articles/s41588-018-0269-7
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http://dx.doi.org/10.1038/s41588-018-0269-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481311PMC
January 2019

Differential anxiety-related behaviours and brain activation in Tph2-deficient female mice exposed to adverse early environment.

Eur Neuropsychopharmacol 2018 11 23;28(11):1270-1283. Epub 2018 Aug 23.

Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Center of Mental Health, Department of Psychiatry, University of Würzburg, Würzburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S0924977X183028
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http://dx.doi.org/10.1016/j.euroneuro.2018.07.103DOI Listing
November 2018

The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis.

Am J Med Genet B Neuropsychiatr Genet 2018 Nov 25. Epub 2018 Nov 25.

Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.

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http://doi.wiley.com/10.1002/ajmg.b.32695
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http://dx.doi.org/10.1002/ajmg.b.32695DOI Listing
November 2018

Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment.

CNS Neurosci Ther 2018 09 24;24(9):763-774. Epub 2018 Apr 24.

Department of Normal Physiology, Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, Russia.

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http://doi.wiley.com/10.1111/cns.12866
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http://dx.doi.org/10.1111/cns.12866DOI Listing
September 2018

Family environment interacts with CRHR1 rs17689918 to predict mental health and behavioral outcomes.

Prog Neuropsychopharmacol Biol Psychiatry 2018 08 14;86:45-51. Epub 2018 May 14.

Division of Neuropsychopharmacology, Department of Psychology, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1016/j.pnpbp.2018.05.004DOI Listing
August 2018

Genetic variation in serotonin function impacts on altruistic punishment in the ultimatum game: A longitudinal approach.

Brain Cogn 2018 08 30;125:37-44. Epub 2018 May 30.

Faculty of Psychology, Technische Universität Dresden, Dresden, Germany; Department of Psychology, Faculty of Science, MSB Medical School Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.bandc.2018.05.007DOI Listing
August 2018

Expression of the ADHD candidate gene Diras2 in the brain.

J Neural Transm (Vienna) 2018 Jun 27;125(6):913-923. Epub 2018 Feb 27.

Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Heinrich-Hoffmann-Str. 10, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00702-018-1867-3DOI Listing
June 2018

Analysis of shared heritability in common disorders of the brain.

Authors:
Verneri Anttila Brendan Bulik-Sullivan Hilary K Finucane Raymond K Walters Jose Bras Laramie Duncan Valentina Escott-Price Guido J Falcone Padhraig Gormley Rainer Malik Nikolaos A Patsopoulos Stephan Ripke Zhi Wei Dongmei Yu Phil H Lee Patrick Turley Benjamin Grenier-Boley Vincent Chouraki Yoichiro Kamatani Claudine Berr Luc Letenneur Didier Hannequin Philippe Amouyel Anne Boland Jean-François Deleuze Emmanuelle Duron Badri N Vardarajan Christiane Reitz Alison M Goate Matthew J Huentelman M Ilyas Kamboh Eric B Larson Ekaterina Rogaeva Peter St George-Hyslop Hakon Hakonarson Walter A Kukull Lindsay A Farrer Lisa L Barnes Thomas G Beach F Yesim Demirci Elizabeth Head Christine M Hulette Gregory A Jicha John S K Kauwe Jeffrey A Kaye James B Leverenz Allan I Levey Andrew P Lieberman Vernon S Pankratz Wayne W Poon Joseph F Quinn Andrew J Saykin Lon S Schneider Amanda G Smith Joshua A Sonnen Robert A Stern Vivianna M Van Deerlin Linda J Van Eldik Denise Harold Giancarlo Russo David C Rubinsztein Anthony Bayer Magda Tsolaki Petra Proitsi Nick C Fox Harald Hampel Michael J Owen Simon Mead Peter Passmore Kevin Morgan Markus M Nöthen Martin Rossor Michelle K Lupton Per Hoffmann Johannes Kornhuber Brian Lawlor Andrew McQuillin Ammar Al-Chalabi Joshua C Bis Agustin Ruiz Mercè Boada Sudha Seshadri Alexa Beiser Kenneth Rice Sven J van der Lee Philip L De Jager Daniel H Geschwind Matthias Riemenschneider Steffi Riedel-Heller Jerome I Rotter Gerhard Ransmayr Bradley T Hyman Carlos Cruchaga Montserrat Alegret Bendik Winsvold Priit Palta Kai-How Farh Ester Cuenca-Leon Nicholas Furlotte Tobias Kurth Lannie Ligthart Gisela M Terwindt Tobias Freilinger Caroline Ran Scott D Gordon Guntram Borck Hieab H H Adams Terho Lehtimäki Juho Wedenoja Julie E Buring Markus Schürks Maria Hrafnsdottir Jouke-Jan Hottenga Brenda Penninx Ville Artto Mari Kaunisto Salli Vepsäläinen Nicholas G Martin Grant W Montgomery Mitja I Kurki Eija Hämäläinen Hailiang Huang Jie Huang Cynthia Sandor Caleb Webber Bertram Muller-Myhsok Stefan Schreiber Veikko Salomaa Elizabeth Loehrer Hartmut Göbel Alfons Macaya Patricia Pozo-Rosich Thomas Hansen Thomas Werge Jaakko Kaprio Andres Metspalu Christian Kubisch Michel D Ferrari Andrea C Belin Arn M J M van den Maagdenberg John-Anker Zwart Dorret Boomsma Nicholas Eriksson Jes Olesen Daniel I Chasman Dale R Nyholt Andreja Avbersek Larry Baum Samuel Berkovic Jonathan Bradfield Russell Buono Claudia B Catarino Patrick Cossette Peter De Jonghe Chantal Depondt Dennis Dlugos Thomas N Ferraro Jacqueline French Helle Hjalgrim Jennifer Jamnadas-Khoda Reetta Kälviäinen Wolfram S Kunz Holger Lerche Costin Leu Dick Lindhout Warren Lo Daniel Lowenstein Mark McCormack Rikke S Møller Anne Molloy Ping-Wing Ng Karen Oliver Michael Privitera Rodney Radtke Ann-Kathrin Ruppert Thomas Sander Steven Schachter Christoph Schankin Ingrid Scheffer Susanne Schoch Sanjay M Sisodiya Philip Smith Michael Sperling Pasquale Striano Rainer Surges G Neil Thomas Frank Visscher Christopher D Whelan Federico Zara Erin L Heinzen Anthony Marson Felicitas Becker Hans Stroink Fritz Zimprich Thomas Gasser Raphael Gibbs Peter Heutink Maria Martinez Huw R Morris Manu Sharma Mina Ryten Kin Y Mok Sara Pulit Steve Bevan Elizabeth Holliday John Attia Thomas Battey Giorgio Boncoraglio Vincent Thijs Wei-Min Chen Braxton Mitchell Peter Rothwell Pankaj Sharma Cathie Sudlow Astrid Vicente Hugh Markus Christina Kourkoulis Joana Pera Miriam Raffeld Scott Silliman Vesna Boraska Perica Laura M Thornton Laura M Huckins N William Rayner Cathryn M Lewis Monica Gratacos Filip Rybakowski Anna Keski-Rahkonen Anu Raevuori James I Hudson Ted Reichborn-Kjennerud Palmiero Monteleone Andreas Karwautz Katrin Mannik Jessica H Baker Julie K O'Toole Sara E Trace Oliver S P Davis Sietske G Helder Stefan Ehrlich Beate Herpertz-Dahlmann Unna N Danner Annemarie A van Elburg Maurizio Clementi Monica Forzan Elisa Docampo Jolanta Lissowska Joanna Hauser Alfonso Tortorella Mario Maj Fragiskos Gonidakis Konstantinos Tziouvas Hana Papezova Zeynep Yilmaz Gudrun Wagner Sarah Cohen-Woods Stefan Herms Antonio Julià Raquel Rabionet Danielle M Dick Samuli Ripatti Ole A Andreassen Thomas Espeseth Astri J Lundervold Vidar M Steen Dalila Pinto Stephen W Scherer Harald Aschauer Alexandra Schosser Lars Alfredsson Leonid Padyukov Katherine A Halmi James Mitchell Michael Strober Andrew W Bergen Walter Kaye Jin Peng Szatkiewicz Bru Cormand Josep Antoni Ramos-Quiroga Cristina Sánchez-Mora Marta Ribasés Miguel Casas Amaia Hervas Maria Jesús Arranz Jan Haavik Tetyana Zayats Stefan Johansson Nigel Williams Astrid Dempfle Aribert Rothenberger Jonna Kuntsi Robert D Oades Tobias Banaschewski Barbara Franke Jan K Buitelaar Alejandro Arias Vasquez Alysa E Doyle Andreas Reif Klaus-Peter Lesch Christine Freitag Olga Rivero Haukur Palmason Marcel Romanos Kate Langley Marcella Rietschel Stephanie H Witt Soeren Dalsgaard Anders D Børglum Irwin Waldman Beth Wilmot Nikolas Molly Claiton H D Bau Jennifer Crosbie Russell Schachar Sandra K Loo James J McGough Eugenio H Grevet Sarah E Medland Elise Robinson Lauren A Weiss Elena Bacchelli Anthony Bailey Vanessa Bal Agatino Battaglia Catalina Betancur Patrick Bolton Rita Cantor Patrícia Celestino-Soper Geraldine Dawson Silvia De Rubeis Frederico Duque Andrew Green Sabine M Klauck Marion Leboyer Pat Levitt Elena Maestrini Shrikant Mane Daniel Moreno- De-Luca Jeremy Parr Regina Regan Abraham Reichenberg Sven Sandin Jacob Vorstman Thomas Wassink Ellen Wijsman Edwin Cook Susan Santangelo Richard Delorme Bernadette Rogé Tiago Magalhaes Dan Arking Thomas G Schulze Robert C Thompson Jana Strohmaier Keith Matthews Ingrid Melle Derek Morris Douglas Blackwood Andrew McIntosh Sarah E Bergen Martin Schalling Stéphane Jamain Anna Maaser Sascha B Fischer Céline S Reinbold Janice M Fullerton José Guzman-Parra Fermin Mayoral Peter R Schofield Sven Cichon Thomas W Mühleisen Franziska Degenhardt Johannes Schumacher Michael Bauer Philip B Mitchell Elliot S Gershon John Rice James B Potash Peter P Zandi Nick Craddock I Nicol Ferrier Martin Alda Guy A Rouleau Gustavo Turecki Roel Ophoff Carlos Pato Adebayo Anjorin Eli Stahl Markus Leber Piotr M Czerski Cristiana Cruceanu Ian R Jones Danielle Posthuma Till F M Andlauer Andreas J Forstner Fabian Streit Bernhard T Baune Tracy Air Grant Sinnamon Naomi R Wray Donald J MacIntyre David Porteous Georg Homuth Margarita Rivera Jakob Grove Christel M Middeldorp Ian Hickie Michele Pergadia Divya Mehta Johannes H Smit Rick Jansen Eco de Geus Erin Dunn Qingqin S Li Matthias Nauck Robert A Schoevers Aartjan Tf Beekman James A Knowles Alexander Viktorin Paul Arnold Cathy L Barr Gabriel Bedoya-Berrio O Joseph Bienvenu Helena Brentani Christie Burton Beatriz Camarena Carolina Cappi Danielle Cath Maria Cavallini Daniele Cusi Sabrina Darrow Damiaan Denys Eske M Derks Andrea Dietrich Thomas Fernandez Martijn Figee Nelson Freimer Gloria Gerber Marco Grados Erica Greenberg Gregory L Hanna Andreas Hartmann Matthew E Hirschtritt Pieter J Hoekstra Alden Huang Chaim Huyser Cornelia Illmann Michael Jenike Samuel Kuperman Bennett Leventhal Christine Lochner Gholson J Lyon Fabio Macciardi Marcos Madruga-Garrido Irene A Malaty Athanasios Maras Lauren McGrath Eurípedes C Miguel Pablo Mir Gerald Nestadt Humberto Nicolini Michael S Okun Andrew Pakstis Peristera Paschou John Piacentini Christopher Pittenger Kerstin Plessen Vasily Ramensky Eliana M Ramos Victor Reus Margaret A Richter Mark A Riddle Mary M Robertson Veit Roessner Maria Rosário Jack F Samuels Paul Sandor Dan J Stein Fotis Tsetsos Filip Van Nieuwerburgh Sarah Weatherall Jens R Wendland Tomasz Wolanczyk Yulia Worbe Gwyneth Zai Fernando S Goes Nicole McLaughlin Paul S Nestadt Hans-Jorgen Grabe Christel Depienne Anuar Konkashbaev Nuria Lanzagorta Ana Valencia-Duarte Elvira Bramon Nancy Buccola Wiepke Cahn Murray Cairns Siow A Chong David Cohen Benedicto Crespo-Facorro James Crowley Michael Davidson Lynn DeLisi Timothy Dinan Gary Donohoe Elodie Drapeau Jubao Duan Lieuwe Haan David Hougaard Sena Karachanak-Yankova Andrey Khrunin Janis Klovins Vaidutis Kučinskas Jimmy Lee Chee Keong Svetlana Limborska Carmel Loughland Jouko Lönnqvist Brion Maher Manuel Mattheisen Colm McDonald Kieran C Murphy Igor Nenadic Jim van Os Christos Pantelis Michele Pato Tracey Petryshen Digby Quested Panos Roussos Alan R Sanders Ulrich Schall Sibylle G Schwab Kang Sim Hon-Cheong So Elisabeth Stögmann Mythily Subramaniam Draga Toncheva John Waddington James Walters Mark Weiser Wei Cheng Robert Cloninger David Curtis Pablo V Gejman Frans Henskens Morten Mattingsdal Sang-Yun Oh Rodney Scott Bradley Webb Gerome Breen Claire Churchhouse Cynthia M Bulik Mark Daly Martin Dichgans Stephen V Faraone Rita Guerreiro Peter Holmans Kenneth S Kendler Bobby Koeleman Carol A Mathews Alkes Price Jeremiah Scharf Pamela Sklar Julie Williams Nicholas W Wood Chris Cotsapas Aarno Palotie Jordan W Smoller Patrick Sullivan Jonathan Rosand Aiden Corvin Benjamin M Neale Jonathan M Schott Richard Anney Josephine Elia Maria Grigoroiu-Serbanescu Howard J Edenberg Robin Murray

Science 2018 06;360(6395)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1126/science.aap8757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097237PMC
June 2018

Autism-Like Behaviours and Memory Deficits Result from a Western Diet in Mice.

Neural Plast 2017 8;2017:9498247. Epub 2017 Jun 8.

Department of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 40, 6200 MD Maastricht, Netherlands.

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http://dx.doi.org/10.1155/2017/9498247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480052PMC
April 2018

Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3.

Stem Cell Res 2018 04 13;28:136-140. Epub 2018 Feb 13.

Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, Russia; Department of Translational Neuroscience, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18735061183004
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http://dx.doi.org/10.1016/j.scr.2018.02.005DOI Listing
April 2018

'Shine bright like a diamond!': is research on high-functioning ADHD at last entering the mainstream?

J Child Psychol Psychiatry 2018 03;59(3):191-192

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http://dx.doi.org/10.1111/jcpp.12887DOI Listing
March 2018

Increased functional coupling of 5-HT autoreceptors to GIRK channels in Tph2 mice.

Eur Neuropsychopharmacol 2017 12 8;27(12):1258-1267. Epub 2017 Nov 8.

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1016/j.euroneuro.2017.10.033DOI Listing
December 2017

Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex.

Authors:
Tulio Guadalupe Samuel R Mathias Theo G M vanErp Christopher D Whelan Marcel P Zwiers Yoshinari Abe Lucija Abramovic Ingrid Agartz Ole A Andreassen Alejandro Arias-Vásquez Benjamin S Aribisala Nicola J Armstrong Volker Arolt Eric Artiges Rosa Ayesa-Arriola Vatche G Baboyan Tobias Banaschewski Gareth Barker Mark E Bastin Bernhard T Baune John Blangero Arun L W Bokde Premika S W Boedhoe Anushree Bose Silvia Brem Henry Brodaty Uli Bromberg Samantha Brooks Christian Büchel Jan Buitelaar Vince D Calhoun Dara M Cannon Anna Cattrell Yuqi Cheng Patricia J Conrod Annette Conzelmann Aiden Corvin Benedicto Crespo-Facorro Fabrice Crivello Udo Dannlowski Greig I de Zubicaray Sonja M C de Zwarte Ian J Deary Sylvane Desrivières Nhat Trung Doan Gary Donohoe Erlend S Dørum Stefan Ehrlich Thomas Espeseth Guillén Fernández Herta Flor Jean-Paul Fouche Vincent Frouin Masaki Fukunaga Jürgen Gallinat Hugh Garavan Michael Gill Andrea Gonzalez Suarez Penny Gowland Hans J Grabe Dominik Grotegerd Oliver Gruber Saskia Hagenaars Ryota Hashimoto Tobias U Hauser Andreas Heinz Derrek P Hibar Pieter J Hoekstra Martine Hoogman Fleur M Howells Hao Hu Hilleke E Hulshoff Pol Chaim Huyser Bernd Ittermann Neda Jahanshad Erik G Jönsson Sarah Jurk Rene S Kahn Sinead Kelly Bernd Kraemer Harald Kugel Jun Soo Kwon Herve Lemaitre Klaus-Peter Lesch Christine Lochner Michelle Luciano Andre F Marquand Nicholas G Martin Ignacio Martínez-Zalacaín Jean-Luc Martinot David Mataix-Cols Karen Mather Colm McDonald Katie L McMahon Sarah E Medland José M Menchón Derek W Morris Omar Mothersill Susana Munoz Maniega Benson Mwangi Takashi Nakamae Tomohiro Nakao Janardhanan C Narayanaswaamy Frauke Nees Jan E Nordvik A Marten H Onnink Nils Opel Roel Ophoff Marie-Laure Paillère Martinot Dimitri Papadopoulos Orfanos Paul Pauli Tomáš Paus Luise Poustka Janardhan Yc Reddy Miguel E Renteria Roberto Roiz-Santiáñez Annerine Roos Natalie A Royle Perminder Sachdev Pascual Sánchez-Juan Lianne Schmaal Gunter Schumann Elena Shumskaya Michael N Smolka Jair C Soares Carles Soriano-Mas Dan J Stein Lachlan T Strike Roberto Toro Jessica A Turner Nathalie Tzourio-Mazoyer Anne Uhlmann Maria Valdés Hernández Odile A van den Heuvel Dennis van der Meer Neeltje E M van Haren Dick J Veltman Ganesan Venkatasubramanian Nora C Vetter Daniella Vuletic Susanne Walitza Henrik Walter Esther Walton Zhen Wang Joanna Wardlaw Wei Wen Lars T Westlye Robert Whelan Katharina Wittfeld Thomas Wolfers Margaret J Wright Jian Xu Xiufeng Xu Je-Yeon Yun JingJing Zhao Barbara Franke Paul M Thompson David C Glahn Bernard Mazoyer Simon E Fisher Clyde Francks

Brain Imaging Behav 2017 Oct;11(5):1497-1514

Language & Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540813PMC
October 2017

Elucidating the functions of brain GSK3α: Possible synergy with GSK3β upregulation and reversal by antidepressant treatment in a mouse model of depressive-like behaviour.

Behav Brain Res 2017 09 10;335:122-127. Epub 2017 Aug 10.

Sechenov First Moscow State Medical University, Institute of Molecular Medicine, Laboratory of Psychiatric Neurobiology and Department of Normal Physiology, Moscow, Russia; Department of Neuroscience, Maastricht University, Maastricht University, Maastricht, Netherlands; Division of Molecular Psychiatry, Clinical Research Unit on Disorders of Neurodevelopment and Cognition, Center of Mental Health, University of Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2017.08.018DOI Listing
September 2017

Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer's-like disease in mice.

Alzheimers Res Ther 2017 Sep 12;9(1):74. Epub 2017 Sep 12.

Department of Neurobiology, Institute of Molecular Medicine, University of Southern Denmark, J.B. Winsløws Vej 25, 5000, Odense C, Denmark.

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http://dx.doi.org/10.1186/s13195-017-0298-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596844PMC
September 2017

Individual Differences in Behavioural Despair Predict Brain GSK-3beta Expression in Mice: The Power of a Modified Swim Test.

Neural Plast 2016 5;2016:5098591. Epub 2016 Jul 5.

Department of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, Netherlands; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Fuechsleinstrasse 15, 97080 Wuerzburg, Germany.

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http://dx.doi.org/10.1155/2016/5098591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949347PMC
August 2017

Postnatal LPS Challenge Impacts Escape Learning and Expression of Plasticity Factors Mmp9 and Timp1 in Rats: Effects of Repeated Training.

Neurotox Res 2017 Aug 18;32(2):175-186. Epub 2017 Apr 18.

Laboratory of Neurobiology of the Brain Integrative Functions, I.P. Pavlov Department of Physiology, Institute of Experimental Medicine, Akademika Pavlova 12, 197376, St. Petersburg, Russia.

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http://link.springer.com/10.1007/s12640-017-9720-2
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http://dx.doi.org/10.1007/s12640-017-9720-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493723PMC
August 2017

T-cadherin promotes autophagy and survival in vascular smooth muscle cells through MEK1/2/Erk1/2 axis activation.

Cell Signal 2017 07 6;35:163-175. Epub 2017 Apr 6.

Department of Biomedicine, Laboratory for Signal Transduction, Basel University Hospital and University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.cellsig.2017.04.004DOI Listing
July 2017

Rsk2 Knockout Affects Emotional Behavior in the IntelliCage.

Behav Genet 2017 07 6;47(4):434-448. Epub 2017 Jun 6.

Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital of Wuerzburg, Margarete-Höppel-Platz 1, 97080, Wuerzburg, Germany.

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http://dx.doi.org/10.1007/s10519-017-9853-3DOI Listing
July 2017

Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice.

Prog Neuropsychopharmacol Biol Psychiatry 2017 04 5;75:148-156. Epub 2016 Nov 5.

EURON - European Graduate School for Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 40, NL 6229 ER Maastricht, Netherlands; I.M.Sechenov First Moscow Medical University, Moscow, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2016.11.001DOI Listing
April 2017

Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis.

Lancet Psychiatry 2017 04 16;4(4):310-319. Epub 2017 Feb 16.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands; Department of Psychiatry, Radboud University Medical Center, Nijmegen, Netherlands; Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands.

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http://dx.doi.org/10.1016/S2215-0366(17)30049-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933934PMC
April 2017

Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism.

Neuropsychopharmacology 2016 12 1;41(13):3025-3031. Epub 2016 Jul 1.

Department of Psychiatry, Psychosomatics and Psychotherapy, Translational Psychiatry, University Hospital Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1038/npp.2016.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101550PMC
December 2016

Sex- and Subtype-Related Differences of Personality Disorders (Axis II) and Personality Traits in Persistent ADHD.

J Atten Disord 2016 12 7;20(12):1056-1065. Epub 2014 Feb 7.

Department of Psychiatry, Psychsomatics and Psychotherapy, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1177/1087054714521293DOI Listing
December 2016

Early citalopram treatment increases mortality due to left ventricular rupture in mice after myocardial infarction.

J Mol Cell Cardiol 2016 09 7;98:28-36. Epub 2016 Jul 7.

Medical Clinic and Policlinic III, University Hospital of Halle (Saale), Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2016.07.002DOI Listing
September 2016

Meta-analysis of the DRD5 VNTR in persistent ADHD.

Eur Neuropsychopharmacol 2016 09 29;26(9):1527-1532. Epub 2016 Jul 29.

Radboud university medical center, Donders Institute for Brain, Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands; Radboud university medical center, Donders Institute for Brain, Cognition and Behaviour, Department of Psychiatry, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2016.06.012DOI Listing
September 2016

Methylphenidate and emotional-motivational processing in attention-deficit/hyperactivity disorder.

J Neural Transm (Vienna) 2016 08 6;123(8):971-9. Epub 2016 Feb 6.

Department of Psychology, Biological Psychology, Clinical Psychology, and Psychotherapy, University of Würzburg, Marcusstr. 9-11, 97070, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00702-016-1512-yDOI Listing
August 2016

Developmental exposure to acetaminophen does not induce hyperactivity in zebrafish larvae.

J Neural Transm (Vienna) 2016 08 26;123(8):841-8. Epub 2016 Apr 26.

Department of Physiological Chemistry, Biocenter, Am Hubland, University of Würzburg, 97074, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00702-016-1556-zDOI Listing
August 2016

The role of ASTN2 variants in childhood and adult ADHD, comorbid disorders and associated personality traits.

J Neural Transm (Vienna) 2016 08 30;123(8):849-58. Epub 2016 Apr 30.

Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00702-016-1553-2DOI Listing
August 2016

Ultrasound of alternating frequencies and variable emotional impact evokes depressive syndrome in mice and rats.

Prog Neuropsychopharmacol Biol Psychiatry 2016 Jul 29;68:52-63. Epub 2016 Mar 29.

Department of Basic and Applied Neurobiology, V.P. Serbsky Federal Medical Research Center for Psychiatry and Narcology, Moscow, Russia; Department of Medical Nanobiotechnology, Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2016.03.003DOI Listing
July 2016

The Unexpected Effects of Beneficial and Adverse Social Experiences during Adolescence on Anxiety and Aggression and Their Modulation by Genotype.

Front Behav Neurosci 2016 26;10:97. Epub 2016 May 26.

Department of Behavioural Biology, University of MuensterMuenster, Germany; Muenster Graduate School of Evolution, University of MuensterMuenster, Germany.

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http://dx.doi.org/10.3389/fnbeh.2016.00097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880570PMC
June 2016

Insulin receptor sensitizer, dicholine succinate, prevents both Toll-like receptor 4 (TLR4) upregulation and affective changes induced by a high-cholesterol diet in mice.

J Affect Disord 2016 May 18;196:109-16. Epub 2016 Feb 18.

Department of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 40, 6200 MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.jad.2016.02.045DOI Listing
May 2016

Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors.

PLoS One 2015 6;10(3):e0116316. Epub 2015 Mar 6.

Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Budapest, Hungary; MTA-SE Neuropsychopharmacology and Neurochemistry Research Group, Hungarian Academy of Sciences, Semmelweis University, Budapest, Hungary.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116316PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351953PMC
February 2016

Reducing central serotonin in adulthood promotes hippocampal neurogenesis.

Sci Rep 2016 Feb 3;6:20338. Epub 2016 Feb 3.

Key Laboratory of Arrhythmias, Ministry of Education, East Hospital, Tongji University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1038/srep20338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738271PMC
February 2016

Hope for the best or prepare for the worst? Towards a spatial cognitive bias test for mice.

PLoS One 2014 19;9(8):e105431. Epub 2014 Aug 19.

Department of Behavioural Biology, University of Münster, Münster, Germany; Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Münster, Münster, Germany; Behavioral Biology, University of Osnabrück, Osnabrück, Germany.

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https://opus.bibliothek.uni-wuerzburg.de/files/11556/054_Klo
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http://dx.plos.org/10.1371/journal.pone.0105431
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105431PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138164PMC
December 2015

Defeat stress in rodents: From behavior to molecules.

Neurosci Biobehav Rev 2015 Dec 22;59:111-40. Epub 2015 Oct 22.

Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, European Graduate School of Neuroscience (EURON), Maastricht University, Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2015.10.006DOI Listing
December 2015

Parkinson's disease, anxious depression and serotonin--zooming in on hippocampal neurogenesis.

J Neurochem 2015 Nov 17;135(3):441-4. Epub 2015 Sep 17.

Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, Julius-Maximilians-University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1111/jnc.13278DOI Listing
November 2015

Cellular resilience: 5-HT neurons in Tph2(-/-) mice retain normal firing behavior despite the lack of brain 5-HT.

Eur Neuropsychopharmacol 2015 Nov 11;25(11):2022-35. Epub 2015 Sep 11.

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2015.08.021DOI Listing
November 2015

Genomic structural variants are linked with intellectual disability.

J Neural Transm (Vienna) 2015 Sep 28;122(9):1289-301. Epub 2015 Jan 28.

N.I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Gubkin str. 3, Moscow, 119991, Russia,

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http://dx.doi.org/10.1007/s00702-015-1366-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517986PMC
September 2015

Tlr4 upregulation in the brain accompanies depression- and anxiety-like behaviors induced by a high-cholesterol diet.

Brain Behav Immun 2015 Aug 21;48:42-7. Epub 2015 Feb 21.

Department of Pharmacology, Oxford University, Mansfield Road, OX1 3QT Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2015.02.015DOI Listing
August 2015

Further evidence for the association of the NPSR1 gene A/T polymorphism (Asn107Ile) with impulsivity and hyperactivity.

J Psychopharmacol 2015 Aug 5;29(8):878-83. Epub 2015 Mar 5.

Division of Neuropsychopharmacology, University of Tartu, Tartu, Estonia

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http://journals.sagepub.com/doi/10.1177/0269881115573803
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August 2015

Differential effects of prenatal stress in female 5-HTT-deficient mice: towards molecular mechanisms of resilience.

Dev Neurosci 2014 4;36(6):454-64. Epub 2014 Sep 4.

Department of Neuroscience, School for Mental Health and Neuroscience (MHENS), Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1159/000363695DOI Listing
July 2015

Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice.

Psychopharmacology (Berl) 2015 Jul 27;232(14):2429-41. Epub 2015 Feb 27.

Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1007/s00213-015-3879-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480945PMC
July 2015

Methylone-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters.

Behav Pharmacol 2015 Jun;26(4):345-52

aDepartment of Biological Psychiatry, Tohoku University Graduate School of Medicine, Sendai bDivision of Pharmacognosy, Phytochemistry, and Narcotics, National Institute of Health Sciences, Tokyo cDepartment of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan dDepartment of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, Ohio eLaboratory of Clinical Science, National Institute of Mental Health, Bethesda fMolecular Neurobiology Branch, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland, USA gDepartment of Psychiatry, University of Wurzburg, Wurzburg, Germany hDepartment of Geriatrics, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.1097/FBP.0000000000000135DOI Listing
June 2015

A preliminary study on methylphenidate-regulated gene expression in lymphoblastoid cells of ADHD patients.

World J Biol Psychiatry 2015 Apr 27;16(3):180-9. Epub 2014 Aug 27.

Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg , Würzburg , Germany.

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http://dx.doi.org/10.3109/15622975.2014.948064DOI Listing
April 2015

Benefits of a "vulnerability gene"? A study in serotonin transporter knockout mice.

Behav Brain Res 2015 Apr 25;283:116-20. Epub 2015 Jan 25.

Department of Behavioural Biology, University of Münster, Badestraße 13, 48149 Münster, Germany.

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http://dx.doi.org/10.1016/j.bbr.2015.01.031DOI Listing
April 2015

Annual research review: The (epi)genetics of neurodevelopmental disorders in the era of whole-genome sequencing--unveiling the dark matter.

J Child Psychol Psychiatry 2015 Mar 11;56(3):278-95. Epub 2015 Feb 11.

Division of Molecular Psychiatry, Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Wuerzburg, Wuerzburg, Germany.

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http://doi.wiley.com/10.1111/jcpp.12392
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March 2015

Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and mRNAs of NMDA receptor subunits in mouse models of depression.

Front Behav Neurosci 2015 26;9:37. Epub 2015 Feb 26.

Department of Neuroscience, Maastricht University Maastricht, Netherlands ; Group of Behavioural Neuroscience and Pharmacology, Institute for Hygiene and Tropical Medicine, New University of Lisbon Lisbon, Portugal ; Laboratory of Biomolecular Screening, Institute of Physiologically Active Compounds, Russian Academy of Sciences Moscow, Russia.

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http://dx.doi.org/10.3389/fnbeh.2015.00037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341562PMC
March 2015

Benefits of adversity?! How life history affects the behavioral profile of mice varying in serotonin transporter genotype.

Front Behav Neurosci 2015 3;9:47. Epub 2015 Mar 3.

Department of Behavioural Biology, University of Muenster Muenster, Germany ; Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Muenster Muenster, Germany.

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http://dx.doi.org/10.3389/fnbeh.2015.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347490PMC
March 2015

Attenuated methamphetamine-induced locomotor sensitization in serotonin transporter knockout mice is restored by serotonin 1B receptor antagonist treatment.

Behav Pharmacol 2015 Feb;26(1-2):167-79

Departments of aBiological Psychiatry bGynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai cDepartment of Molecular Psychiatry, Tokyo Institute of Psychiatry, Tokyo, Japan dDepartment of Psychiatry und Psychotherapy, University of Wurzburg, Wurzburg, Germany eClinical Neuropharmacology Section, Laboratory of Clinical Science, National Institute on Mental Health, Intramural Research Program, Bethesda fMolecular Neurobiology Branch, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/FBP.0000000000000120DOI Listing
February 2015

Lasting downregulation of the lipid peroxidation enzymes in the prefrontal cortex of mice susceptible to stress-induced anhedonia.

Behav Brain Res 2015 Jan 28;276:118-29. Epub 2014 Apr 28.

Maastricht Medical Centre in Annadal, Department of Preventive Medicine, Becanusstraat 17 A0, 6216 BX Maastricht, Netherlands; Department of Neuroscience, Maastricht University, Universiteitssingel 40, NL 6229 ER Maastricht, Netherlands; Institute of Physiologically Active Compounds RAS, Severnii proesd 1, 142100 Chernogolovka, Moscow Region, Russia; Institute for Hygiene and Tropical Medicine, New University of Lisbon, Lisbon, Portugal. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01664328140025
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http://dx.doi.org/10.1016/j.bbr.2014.04.037DOI Listing
January 2015

Pharmacoepigenetics of depression: no major influence of MAO-A DNA methylation on treatment response.

J Neural Transm (Vienna) 2015 Jan 10;122(1):99-108. Epub 2014 May 10.

Department of Psychiatry, University of Wuerzburg, Fuechsleinstrasse 15, 97080, Wurzburg, Germany,

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http://dx.doi.org/10.1007/s00702-014-1227-xDOI Listing
January 2015

Endotoxaemia resulting from decreased serotonin tranporter (5-HTT) function: a reciprocal risk factor for depression and insulin resistance?

Behav Brain Res 2015 Jan 9;276:111-7. Epub 2014 May 9.

Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Universiteitssingel 40, NL 6229 ER Maastricht, Netherlands; Institute of Physiologically Active Compounds RAS, Severnii proesd 1, 142432 Chernogolovka, Moscow region, Russia; Institute for Hygiene and Tropical Medicine, New University of Lisbon, Rua da Junqueira, 96, 1349-008 Lisboa, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2014.04.049DOI Listing
January 2015

Deuterium content of water increases depression susceptibility: the potential role of a serotonin-related mechanism.

Behav Brain Res 2015 Jan 1;277:237-44. Epub 2014 Aug 1.

School for Mental Health and Neuroscience, Department of Neuroscience, Maastricht University, Maastricht, Netherlands; Division of Molecular Psychiatry, Laboratory of Translational Neuroscience, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2014.07.039DOI Listing
January 2015

Multi-level biomarker analysis of nitric oxide synthase isoforms in bipolar disorder and adult ADHD.

J Psychopharmacol 2015 Jan 15;29(1):31-8. Epub 2014 Oct 15.

Department of Psychiatry, Psychosomatics and Psychotherapy, Johann Wolfgang Goethe University Frankfurt, Frankfurt, Germany Comprehensive Heart Failure Center, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1177/0269881114555251DOI Listing
January 2015

Experimental heart failure causes depression-like behavior together with differential regulation of inflammatory and structural genes in the brain.

Front Behav Neurosci 2014 31;8:376. Epub 2014 Oct 31.

Medical Clinic and Policlinic I, University Hospital of Würzburg Würzburg, Germany ; Comprehensive Heart Failure Center, University Hospital of Würzburg Würzburg, Germany.

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http://dx.doi.org/10.3389/fnbeh.2014.00376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215623PMC
November 2014

Developmental alterations in anxiety and cognitive behavior in serotonin transporter mutant mice.

Psychopharmacology (Berl) 2014 Oct 13;231(21):4119-33. Epub 2014 Apr 13.

Department of Biological Psychiatry, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan.

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http://dx.doi.org/10.1007/s00213-014-3554-xDOI Listing
October 2014

Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response.

Int J Neuropsychopharmacol 2014 Aug 28;17(8):1167-76. Epub 2014 Mar 28.

Department of Psychiatry,University of Adelaide,Australia.

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http://dx.doi.org/10.1017/S146114571400039XDOI Listing
August 2014

Internalizing and externalizing behavior in adult ADHD.

Atten Defic Hyperact Disord 2014 Jun 21;6(2):101-10. Epub 2014 Feb 21.

Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Fuechsleinstr. 15, 97080, Würzburg, Germany,

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http://link.springer.com/10.1007/s12402-014-0128-z
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June 2014

The epigenome and postnatal environmental influences in psychotic disorders.

Soc Psychiatry Psychiatr Epidemiol 2014 Mar 19;49(3):337-48. Epub 2014 Feb 19.

Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.

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http://link.springer.com/10.1007/s00127-014-0831-2
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March 2014

Autonomic hypoactivity in boys with attention-deficit/hyperactivity disorder and the influence of methylphenidate.

World J Biol Psychiatry 2014 Jan 9;15(1):56-65. Epub 2013 Sep 9.

Department of Psychology (Biological Psychology, Clinical Psychology, and Psychotherapy), University of Würzburg , Germany.

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http://dx.doi.org/10.3109/15622975.2013.829584DOI Listing
January 2014

Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression.

Front Behav Neurosci 2013 31;7:215. Epub 2013 Dec 31.

Preclinical Laboratory for Translational Research into Affective Disorders, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich Zurich, Switzerland ; Neuroscience Center, University and ETH Zurich Zurich, Switzerland ; Zurich Center for Integrative Human Physiology, University of Zurich Zurich, Switzerland.

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http://dx.doi.org/10.3389/fnbeh.2013.00215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876674PMC
January 2014