Klaus Holzmann

Klaus Holzmann

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Klaus Holzmann

Klaus Holzmann

Publications by authors named "Klaus Holzmann"

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Long interspersed element-1 ribonucleoprotein particles protect telomeric ends in alternative lengthening of telomeres dependent cells.

Neoplasia 2019 Dec 14;22(2):61-75. Epub 2019 Dec 14.

Surgical Research Laboratories, Department of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria; Comprehensive Cancer Centre, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2019.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920197PMC
December 2019

Importance of Translational Research for Targeting Fibroblast Growth Factor Receptor Signaling in Cancer.

Cells 2019 10 2;8(10). Epub 2019 Oct 2.

Medical University of Vienna, Comprehensive Cancer Center, Department of Medicine I, Division of Cancer Research, Borschkegasse 8a, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/cells8101191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830323PMC
October 2019

Low doses of widely consumed cannabinoids (cannabidiol and cannabidivarin) cause DNA damage and chromosomal aberrations in human-derived cells.

Arch Toxicol 2019 01 19;93(1):179-188. Epub 2018 Oct 19.

Department of Internal Medicine 1, Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8A, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00204-018-2322-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342871PMC
January 2019

Impact of extended working periods on genomic and telomeric DNA and on inflammatory markers: Results of an intervention study with office workers and carpenters.

Mutat Res Genet Toxicol Environ Mutagen 2018 Dec 5;836(Pt A):78-81. Epub 2018 May 5.

Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2018.05.004DOI Listing
December 2018

High tRNA Transferase NSUN2 Gene Expression is Associated with Poor Prognosis in Head and Neck Squamous Carcinoma.

Cancer Invest 2018 Apr;36(4):246-253

e Division of Cancer Research, Department of Medicine I , Comprehensive Cancer Center, Medical University of Vienna , Austria.

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http://dx.doi.org/10.1080/07357907.2018.1466896DOI Listing
April 2018

Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis.

Transl Oncol 2017 Jun 22;10(3):332-339. Epub 2017 Mar 22.

Medical University of Vienna, Department of Medicine 1, Institute of Cancer Research and Comprehensive Cancer Center Vienna, Borschkegasse 8a, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2017.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367848PMC
June 2017

Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas.

Genes (Basel) 2017 May 17;8(5). Epub 2017 May 17.

Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, Vienna 1090, Austria.

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http://dx.doi.org/10.3390/genes8050145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448019PMC
May 2017

Alternative lengthening of telomeres does exist in various canine sarcomas.

Mol Carcinog 2017 03 22;56(3):923-935. Epub 2016 Sep 22.

Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/mc.22546DOI Listing
March 2017

Telomere Transcripts Target Telomerase in Human Cancer Cells.

Genes (Basel) 2016 Aug 16;7(8). Epub 2016 Aug 16.

Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, Vienna 1090, Austria.

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http://dx.doi.org/10.3390/genes7080046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999834PMC
August 2016

Fibroblast growth factor receptor 3 isoforms: Novel therapeutic targets for hepatocellular carcinoma?

Hepatology 2015 Dec 16;62(6):1767-78. Epub 2015 Oct 16.

Department of Medicine I, Division: Institute of Cancer Research, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/hep.28023DOI Listing
December 2015

Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?

Curr Pharm Des 2014 ;20(17):2881-98

Institute of Cancer Research, Department of Medicine 1, Medical University Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453246PMC
http://dx.doi.org/10.2174/13816128113199990594DOI Listing
September 2015

Canine and human sarcomas exhibit predominant FGFR1 expression and impaired viability after inhibition of signaling.

Mol Carcinog 2015 Sep 9;54(9):841-52. Epub 2014 Apr 9.

Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://doi.wiley.com/10.1002/mc.22155
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http://dx.doi.org/10.1002/mc.22155DOI Listing
September 2015

Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.

Carcinogenesis 2014 Oct 16;35(10):2331-8. Epub 2014 Jul 16.

Department of Medicine I, Division: Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria and Institute of Clinical Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria

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http://carcin.oxfordjournals.org/content/35/10/2331.full.pdf
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http://www.carcin.oxfordjournals.org/cgi/doi/10.1093/carcin/
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http://dx.doi.org/10.1093/carcin/bgu151DOI Listing
October 2014

Alternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer.

J Nucleic Acids 2012 12;2012:950508. Epub 2011 Dec 12.

Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

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http://dx.doi.org/10.1155/2012/950508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238399PMC
August 2012

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells.

Cancer Lett 2012 Jun 17;319(2):164-172. Epub 2012 Jan 17.

Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S030438351200027
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http://dx.doi.org/10.1016/j.canlet.2012.01.002DOI Listing
June 2012

Expression of telomeres in astrocytoma WHO grade 2 to 4: TERRA level correlates with telomere length, telomerase activity, and advanced clinical grade.

Transl Oncol 2012 Feb 1;5(1):56-65. Epub 2012 Feb 1.

Department of Medicine I, Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281409PMC
http://dx.doi.org/10.1593/tlo.11202DOI Listing
February 2012

MNS16A tandem repeats minisatellite of human telomerase gene: a risk factor for colorectal cancer.

Carcinogenesis 2011 Jun 21;32(6):866-71. Epub 2011 Mar 21.

Department of Medicine I, Division: Institute of Cancer Research, Comprehensive Cancer Center, Medical University Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1093/carcin/bgr053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314280PMC
June 2011

Microscopic analysis of adenoviral decontamination using GFP adenovirus with comparable sensitivity to flow cytometry.

Methods Mol Biol 2009 ;515:125-35

Department of Medicine I, Radical University of Vienna, Borschkepasse 8a, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/978-1-59745-559-6_8DOI Listing
May 2009

Daytime levels of melatonin in patients with age-related macular degeneration.

Acta Ophthalmol 2009 Feb 20;87(1):89-93. Epub 2008 May 20.

Department of Ophthalmology, The Ludwig Boltzmann Institute for Retinology and Biomicroscopic Lasersurgery, Vienna, Austria.

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http://dx.doi.org/10.1111/j.1755-3768.2008.01173.xDOI Listing
February 2009

A bicistronic baculovirus vector for transient and stable protein expression in mammalian cells.

Anal Biochem 2008 Sep 22;380(1):146-8. Epub 2008 May 22.

Department of Medicine I, Institute of Cancer Research, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.ab.2008.05.020DOI Listing
September 2008

FGF18 in colorectal tumour cells: autocrine and paracrine effects.

Carcinogenesis 2008 Jan 22;29(1):15-24. Epub 2007 Sep 22.

Department of Medicine I, Institute of Cancer Research, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1093/carcin/bgm202DOI Listing
January 2008

Oncogenic c-H-ras deregulates survivin expression: an improvement for survival.

FEBS Lett 2007 Oct 21;581(25):4921-6. Epub 2007 Sep 21.

Clinics of Internal Medicine I, Division Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.febslet.2007.09.023DOI Listing
October 2007

Assessing 12(S)-lipoxygenase inhibitory activity using colorectal cancer cells overexpressing the enzyme.

Food Chem Toxicol 2007 Mar 30;45(3):508-14. Epub 2006 Aug 30.

Department of Internal Medicine 1, Institute of Cancer Research, Medical University Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

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http://linkinghub.elsevier.com/retrieve/pii/S027869150600245
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http://dx.doi.org/10.1016/j.fct.2006.08.013DOI Listing
March 2007

Monitoring viral decontamination procedures with green fluorescent protein-expressing adenovirus.

Anal Biochem 2006 Aug 4;355(2):310-2. Epub 2006 May 4.

Department of Medicine I, Institute of Cancer Research, Medical University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.ab.2006.04.034DOI Listing
August 2006

The major vault protein is responsive to and interferes with interferon-gamma-mediated STAT1 signals.

J Cell Sci 2006 Feb 17;119(Pt 3):459-69. Epub 2006 Jan 17.

Department of Medicine I, Institute of Cancer Research, Medical University Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1242/jcs.02773DOI Listing
February 2006

SP-transcription factors are involved in basal MVP promoter activity and its stimulation by HDAC inhibitors.

Biochem Biophys Res Commun 2004 Apr;317(1):235-43

Division of Applied and Experimental Oncology, Institute of Cancer Research, Medical University Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0400501
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http://dx.doi.org/10.1016/j.bbrc.2004.03.029DOI Listing
April 2004

Genetic damage following introduction of DNA in Phycomyces.

Fungal Genet Biol 2004 Feb;41(2):168-80

Departamento de Genética, Universidad de Sevilla, E-41012 Sevilla, Spain.

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http://dx.doi.org/10.1016/j.fgb.2003.09.007DOI Listing
February 2004

Chromosomal imbalances in primary and metastatic melanomas: over-representation of essential telomerase genes.

Melanoma Res 2003 Oct;13(5):483-92

Institute of Cancer Research, Division of Applied and Experimental Oncology, and Division of Cell Biology, Borschkegasse 8a, Vienna University, Vienna, Austria.

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http://dx.doi.org/10.1097/00008390-200310000-00007DOI Listing
October 2003

Detection and quantification of transcripts for the catalytic subunit TERT and the RNA component of telomerase in rat tissue.

Anal Biochem 2003 Jun;317(1):120-3

Institute of Cancer Research, University of Vienna, Borschkegasse 8a, A-1090, Vienna, Austria.

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http://dx.doi.org/10.1016/s0003-2697(03)00091-5DOI Listing
June 2003

A Penicillium chrysogenum gene ( aox) identified by specific induction upon shifting pH encodes for a protein which shows high homology to fungal alcohol oxidases.

Curr Genet 2002 Feb 8;40(5):339-44. Epub 2001 Dec 8.

Institut für Biotechnologie, Arbeitsgruppe Genetik, Technische Universität Graz, Austria.

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http://dx.doi.org/10.1007/s002940100251DOI Listing
February 2002