Klaudia Walter

Klaudia Walter

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Klaudia Walter

Publications by authors named "Klaudia Walter"

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Quality Control of Common and Rare Variants.

Methods Mol Biol 2018 ;1793:25-36

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, Cambridgeshire, United Kingdom.

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http://dx.doi.org/10.1007/978-1-4939-7868-7_3DOI Listing
February 2019

Automated typing of red blood cell and platelet antigens: a whole-genome sequencing study.

Lancet Haematol 2018 Jun 17;5(6):e241-e251. Epub 2018 May 17.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Partners Personalized Medicine, Boston, MA, USA; Broad Institute of Massachusetts Institute of Technology and Harvard, Boston, MA, USA.

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http://dx.doi.org/10.1016/S2352-3026(18)30053-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438177PMC
June 2018

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.

Authors:
Ioanna Tachmazidou Dániel Süveges Josine L Min Graham R S Ritchie Julia Steinberg Klaudia Walter Valentina Iotchkova Jeremy Schwartzentruber Jie Huang Yasin Memari Shane McCarthy Andrew A Crawford Cristina Bombieri Massimiliano Cocca Aliki-Eleni Farmaki Tom R Gaunt Pekka Jousilahti Marjolein N Kooijman Benjamin Lehne Giovanni Malerba Satu Männistö Angela Matchan Carolina Medina-Gomez Sarah J Metrustry Abhishek Nag Ioanna Ntalla Lavinia Paternoster Nigel W Rayner Cinzia Sala William R Scott Hashem A Shihab Lorraine Southam Beate St Pourcain Michela Traglia Katerina Trajanoska Gialuigi Zaza Weihua Zhang María S Artigas Narinder Bansal Marianne Benn Zhongsheng Chen Petr Danecek Wei-Yu Lin Adam Locke Jian'an Luan Alisa K Manning Antonella Mulas Carlo Sidore Anne Tybjaerg-Hansen Anette Varbo Magdalena Zoledziewska Chris Finan Konstantinos Hatzikotoulas Audrey E Hendricks John P Kemp Alireza Moayyeri Kalliope Panoutsopoulou Michal Szpak Scott G Wilson Michael Boehnke Francesco Cucca Emanuele Di Angelantonio Claudia Langenberg Cecilia Lindgren Mark I McCarthy Andrew P Morris Børge G Nordestgaard Robert A Scott Martin D Tobin Nicholas J Wareham Paul Burton John C Chambers George Davey Smith George Dedoussis Janine F Felix Oscar H Franco Giovanni Gambaro Paolo Gasparini Christopher J Hammond Albert Hofman Vincent W V Jaddoe Marcus Kleber Jaspal S Kooner Markus Perola Caroline Relton Susan M Ring Fernando Rivadeneira Veikko Salomaa Timothy D Spector Oliver Stegle Daniela Toniolo André G Uitterlinden Inês Barroso Celia M T Greenwood John R B Perry Brian R Walker Adam S Butterworth Yali Xue Richard Durbin Kerrin S Small Nicole Soranzo Nicholas J Timpson Eleftheria Zeggini

Am J Hum Genet 2017 Jun 25;100(6):865-884. Epub 2017 May 25.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473732PMC
June 2017

The impact of rare and low-frequency genetic variants in common disease.

Genome Biol 2017 04 27;18(1):77. Epub 2017 Apr 27.

Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, CB10 1HH, UK.

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http://dx.doi.org/10.1186/s13059-017-1212-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408830PMC
April 2017

An Organismal CNV Mutator Phenotype Restricted to Early Human Development.

Cell 2017 02;168(5):830-842.e7

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Texas Children's Hospital, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407901PMC
February 2017

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

Cell 2016 11;167(5):1398-1414.e24

Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Strangeways Research Laboratory, University of Cambridge, Wort's Causeway, Cambridge CB1 8RN, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674163144
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http://dx.doi.org/10.1016/j.cell.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119954PMC
November 2016

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

Cell 2016 11;167(5):1415-1429.e19

Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300907PMC
November 2016

A reference panel of 64,976 haplotypes for genotype imputation.

Authors:
Shane McCarthy Sayantan Das Warren Kretzschmar Olivier Delaneau Andrew R Wood Alexander Teumer Hyun Min Kang Christian Fuchsberger Petr Danecek Kevin Sharp Yang Luo Carlo Sidore Alan Kwong Nicholas Timpson Seppo Koskinen Scott Vrieze Laura J Scott He Zhang Anubha Mahajan Jan Veldink Ulrike Peters Carlos Pato Cornelia M van Duijn Christopher E Gillies Ilaria Gandin Massimo Mezzavilla Arthur Gilly Massimiliano Cocca Michela Traglia Andrea Angius Jeffrey C Barrett Dorrett Boomsma Kari Branham Gerome Breen Chad M Brummett Fabio Busonero Harry Campbell Andrew Chan Sai Chen Emily Chew Francis S Collins Laura J Corbin George Davey Smith George Dedoussis Marcus Dorr Aliki-Eleni Farmaki Luigi Ferrucci Lukas Forer Ross M Fraser Stacey Gabriel Shawn Levy Leif Groop Tabitha Harrison Andrew Hattersley Oddgeir L Holmen Kristian Hveem Matthias Kretzler James C Lee Matt McGue Thomas Meitinger David Melzer Josine L Min Karen L Mohlke John B Vincent Matthias Nauck Deborah Nickerson Aarno Palotie Michele Pato Nicola Pirastu Melvin McInnis J Brent Richards Cinzia Sala Veikko Salomaa David Schlessinger Sebastian Schoenherr P Eline Slagboom Kerrin Small Timothy Spector Dwight Stambolian Marcus Tuke Jaakko Tuomilehto Leonard H Van den Berg Wouter Van Rheenen Uwe Volker Cisca Wijmenga Daniela Toniolo Eleftheria Zeggini Paolo Gasparini Matthew G Sampson James F Wilson Timothy Frayling Paul I W de Bakker Morris A Swertz Steven McCarroll Charles Kooperberg Annelot Dekker David Altshuler Cristen Willer William Iacono Samuli Ripatti Nicole Soranzo Klaudia Walter Anand Swaroop Francesco Cucca Carl A Anderson Richard M Myers Michael Boehnke Mark I McCarthy Richard Durbin

Nat Genet 2016 10 22;48(10):1279-83. Epub 2016 Aug 22.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.3643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388176PMC
October 2016

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

Authors:
Robert A Scott Daniel F Freitag Li Li Audrey Y Chu Praveen Surendran Robin Young Niels Grarup Alena Stancáková Yuning Chen Tibor V Varga Hanieh Yaghootkar Jian'an Luan Jing Hua Zhao Sara M Willems Jennifer Wessel Shuai Wang Nisa Maruthur Kyriaki Michailidou Ailith Pirie Sven J van der Lee Christopher Gillson Ali Amin Al Olama Philippe Amouyel Larraitz Arriola Dominique Arveiler Iciar Aviles-Olmos Beverley Balkau Aurelio Barricarte Inês Barroso Sara Benlloch Garcia Joshua C Bis Stefan Blankenberg Michael Boehnke Heiner Boeing Eric Boerwinkle Ingrid B Borecki Jette Bork-Jensen Sarah Bowden Carlos Caldas Muriel Caslake L Adrienne Cupples Carlos Cruchaga Jacek Czajkowski Marcel den Hoed Janet A Dunn Helena M Earl Georg B Ehret Ele Ferrannini Jean Ferrieres Thomas Foltynie Ian Ford Nita G Forouhi Francesco Gianfagna Carlos Gonzalez Sara Grioni Louise Hiller Jan-Håkan Jansson Marit E Jørgensen J Wouter Jukema Rudolf Kaaks Frank Kee Nicola D Kerrison Timothy J Key Jukka Kontto Zsofia Kote-Jarai Aldi T Kraja Kari Kuulasmaa Johanna Kuusisto Allan Linneberg Chunyu Liu Gaëlle Marenne Karen L Mohlke Andrew P Morris Kenneth Muir Martina Müller-Nurasyid Patricia B Munroe Carmen Navarro Sune F Nielsen Peter M Nilsson Børge G Nordestgaard Chris J Packard Domenico Palli Salvatore Panico Gina M Peloso Markus Perola Annette Peters Christopher J Poole J Ramón Quirós Olov Rolandsson Carlotta Sacerdote Veikko Salomaa María-José Sánchez Naveed Sattar Stephen J Sharp Rebecca Sims Nadia Slimani Jennifer A Smith Deborah J Thompson Stella Trompet Rosario Tumino Daphne L van der A Yvonne T van der Schouw Jarmo Virtamo Mark Walker Klaudia Walter Jean E Abraham Laufey T Amundadottir Jennifer L Aponte Adam S Butterworth Josée Dupuis Douglas F Easton Rosalind A Eeles Jeanette Erdmann Paul W Franks Timothy M Frayling Torben Hansen Joanna M M Howson Torben Jørgensen Jaspal Kooner Markku Laakso Claudia Langenberg Mark I McCarthy James S Pankow Oluf Pedersen Elio Riboli Jerome I Rotter Danish Saleheen Nilesh J Samani Heribert Schunkert Peter Vollenweider Stephen O'Rahilly Panos Deloukas John Danesh Mark O Goodarzi Sekar Kathiresan James B Meigs Margaret G Ehm Nicholas J Wareham Dawn M Waterworth

Sci Transl Med 2016 06;8(341):341ra76

Genetics, PCPS, GlaxoSmithKline, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad3744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219001PMC
June 2016

An interactive genome browser of association results from the UK10K cohorts project.

Bioinformatics 2015 Dec 26;31(24):4029-31. Epub 2015 Aug 26.

Wellcome Trust Sanger Institute, Genome Campus, Hinxton CB10 1HH, UK, Department of Haematology, University of Cambridge, Cambridge CB2 1TN, UK.

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http://dx.doi.org/10.1093/bioinformatics/btv491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673976PMC
December 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:
Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

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http://dx.doi.org/10.1038/nature14878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714PMC
October 2015

An integrated map of structural variation in 2,504 human genomes.

Nature 2015 Oct;526(7571):75-81

European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Meyerhofstr. 1, 69117 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature15394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617611PMC
October 2015

Estimating genome-wide significance for whole-genome sequencing studies.

Genet Epidemiol 2014 May 14;38(4):281-90. Epub 2014 Feb 14.

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada.

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http://dx.doi.org/10.1002/gepi.21797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489336PMC
May 2014

Accurate whole human genome sequencing using reversible terminator chemistry.

Authors:
David R Bentley Shankar Balasubramanian Harold P Swerdlow Geoffrey P Smith John Milton Clive G Brown Kevin P Hall Dirk J Evers Colin L Barnes Helen R Bignell Jonathan M Boutell Jason Bryant Richard J Carter R Keira Cheetham Anthony J Cox Darren J Ellis Michael R Flatbush Niall A Gormley Sean J Humphray Leslie J Irving Mirian S Karbelashvili Scott M Kirk Heng Li Xiaohai Liu Klaus S Maisinger Lisa J Murray Bojan Obradovic Tobias Ost Michael L Parkinson Mark R Pratt Isabelle M J Rasolonjatovo Mark T Reed Roberto Rigatti Chiara Rodighiero Mark T Ross Andrea Sabot Subramanian V Sankar Aylwyn Scally Gary P Schroth Mark E Smith Vincent P Smith Anastassia Spiridou Peta E Torrance Svilen S Tzonev Eric H Vermaas Klaudia Walter Xiaolin Wu Lu Zhang Mohammed D Alam Carole Anastasi Ify C Aniebo David M D Bailey Iain R Bancarz Saibal Banerjee Selena G Barbour Primo A Baybayan Vincent A Benoit Kevin F Benson Claire Bevis Phillip J Black Asha Boodhun Joe S Brennan John A Bridgham Rob C Brown Andrew A Brown Dale H Buermann Abass A Bundu James C Burrows Nigel P Carter Nestor Castillo Maria Chiara E Catenazzi Simon Chang R Neil Cooley Natasha R Crake Olubunmi O Dada Konstantinos D Diakoumakos Belen Dominguez-Fernandez David J Earnshaw Ugonna C Egbujor David W Elmore Sergey S Etchin Mark R Ewan Milan Fedurco Louise J Fraser Karin V Fuentes Fajardo W Scott Furey David George Kimberley J Gietzen Colin P Goddard George S Golda Philip A Granieri David E Green David L Gustafson Nancy F Hansen Kevin Harnish Christian D Haudenschild Narinder I Heyer Matthew M Hims Johnny T Ho Adrian M Horgan Katya Hoschler Steve Hurwitz Denis V Ivanov Maria Q Johnson Terena James T A Huw Jones Gyoung-Dong Kang Tzvetana H Kerelska Alan D Kersey Irina Khrebtukova Alex P Kindwall Zoya Kingsbury Paula I Kokko-Gonzales Anil Kumar Marc A Laurent Cynthia T Lawley Sarah E Lee Xavier Lee Arnold K Liao Jennifer A Loch Mitch Lok Shujun Luo Radhika M Mammen John W Martin Patrick G McCauley Paul McNitt Parul Mehta Keith W Moon Joe W Mullens Taksina Newington Zemin Ning Bee Ling Ng Sonia M Novo Michael J O'Neill Mark A Osborne Andrew Osnowski Omead Ostadan Lambros L Paraschos Lea Pickering Andrew C Pike Alger C Pike D Chris Pinkard Daniel P Pliskin Joe Podhasky Victor J Quijano Come Raczy Vicki H Rae Stephen R Rawlings Ana Chiva Rodriguez Phyllida M Roe John Rogers Maria C Rogert Bacigalupo Nikolai Romanov Anthony Romieu Rithy K Roth Natalie J Rourke Silke T Ruediger Eli Rusman Raquel M Sanches-Kuiper Martin R Schenker Josefina M Seoane Richard J Shaw Mitch K Shiver Steven W Short Ning L Sizto Johannes P Sluis Melanie A Smith Jean Ernest Sohna Sohna Eric J Spence Kim Stevens Neil Sutton Lukasz Szajkowski Carolyn L Tregidgo Gerardo Turcatti Stephanie Vandevondele Yuli Verhovsky Selene M Virk Suzanne Wakelin Gregory C Walcott Jingwen Wang Graham J Worsley Juying Yan Ling Yau Mike Zuerlein Jane Rogers James C Mullikin Matthew E Hurles Nick J McCooke John S West Frank L Oaks Peter L Lundberg David Klenerman Richard Durbin Anthony J Smith

Nature 2008 Nov;456(7218):53-9

Illumina Cambridge Ltd. (Formerly Solexa Ltd), Chesterford Research Park, Little Chesterford, Nr Saffron Walden, Essex CB10 1XL, UK.

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http://dx.doi.org/10.1038/nature07517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581791PMC
November 2008

Characterisation of conserved non-coding sequences in vertebrate genomes using bioinformatics, statistics and functional studies.

Comp Biochem Physiol Part D Genomics Proteomics 2006 Mar 15;1(1):46-58. Epub 2005 Sep 15.

School of Biological and Chemical Sciences, Queen Mary, University of London, Mile End Road, London, E1 4NS, UK.

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http://dx.doi.org/10.1016/j.cbd.2005.03.001DOI Listing
March 2006

Striking nucleotide frequency pattern at the borders of highly conserved vertebrate non-coding sequences.

Trends Genet 2005 Aug;21(8):436-40

MRC Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge CB10 1SB, UK.

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http://dx.doi.org/10.1016/j.tig.2005.06.003DOI Listing
August 2005

Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome: the fluffy-tail test.

BMC Bioinformatics 2005 Apr 27;6:109. Epub 2005 Apr 27.

MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK.

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http://dx.doi.org/10.1186/1471-2105-6-109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1127108PMC
April 2005