Publications by authors named "Klaas Kok"

68Publications

An All-In-One Transcriptome-Based Assay to Identify Therapy-Guiding Genomic Aberrations in Nonsmall Cell Lung Cancer Patients.

Cancers (Basel) 2020 Oct 1;12(10). Epub 2020 Oct 1.

Department of Genetics, University Medical Centre Groningen, University of Groningen, 9700RB Groningen, The Netherlands.

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http://dx.doi.org/10.3390/cancers12102843DOI Listing
October 2020

Plasma Extracellular Vesicle-Derived TIMP-1 mRNA as a Prognostic Biomarker in Clear Cell Renal Cell Carcinoma: A Pilot Study.

Int J Mol Sci 2020 Jun 29;21(13). Epub 2020 Jun 29.

Molecular Oncology and Viral Pathology Group, IPO-Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO-Porto), Research Center- LAB2, E Bdg 1st floor, Rua Dr António Bernardino de Almeida, 4200-072 Porto, Portugal.

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http://dx.doi.org/10.3390/ijms21134624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370073PMC
June 2020

Combined osimertinib, dabrafenib and trametinib treatment for advanced non-small-cell lung cancer patients with an osimertinib-induced BRAF V600E mutation.

Lung Cancer 2020 08 4;146:358-361. Epub 2020 Jun 4.

Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.05.036DOI Listing
August 2020

The miR-26b-5p/KPNA2 Axis Is an Important Regulator of Burkitt Lymphoma Cell Growth.

Cancers (Basel) 2020 Jun 4;12(6). Epub 2020 Jun 4.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.

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http://dx.doi.org/10.3390/cancers12061464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352454PMC
June 2020

Extracellular Vesicles Enriched in hsa-miR-301a-3p and hsa-miR-1293 Dynamics in Clear Cell Renal Cell Carcinoma Patients: Potential Biomarkers of Metastatic Disease.

Cancers (Basel) 2020 Jun 2;12(6). Epub 2020 Jun 2.

Molecular Oncology and Viral Pathology Group, IPO-Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO-Porto), Research Center- LAB2, E Bdg 1st floor, Rua Dr António Bernardino de Almeida, 4200-072 Porto, Portugal.

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http://dx.doi.org/10.3390/cancers12061450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352268PMC
June 2020

A Novel Role for Bronchial MicroRNAs and Long Noncoding RNAs in Asthma Remission.

Am J Respir Crit Care Med 2020 Aug;202(4):614-618

University Medical Center Groningen, University of GroningenGroningen, the Netherlands.

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http://dx.doi.org/10.1164/rccm.201908-1610LEDOI Listing
August 2020

Mutational heterogeneity between different regional tumour grades of clear cell renal cell carcinoma.

Exp Mol Pathol 2020 08 4;115:104431. Epub 2020 Apr 4.

Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yexmp.2020.104431DOI Listing
August 2020

B Cells as Prognostic Biomarker After Surgery for Colorectal Liver Metastases.

Front Oncol 2020 5;10:249. Epub 2020 Mar 5.

Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

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http://dx.doi.org/10.3389/fonc.2020.00249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066250PMC
March 2020

Current Smoking is Associated with Decreased Expression of miR-335-5p in Parenchymal Lung Fibroblasts.

Int J Mol Sci 2019 Oct 18;20(20). Epub 2019 Oct 18.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, 9713 GZ Groningen, The Netherlands.

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http://dx.doi.org/10.3390/ijms20205176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829537PMC
October 2019

Targeted sequencing of circulating cell-free DNA in stage II-III resectable oesophageal squamous cell carcinoma patients.

BMC Cancer 2019 Aug 20;19(1):818. Epub 2019 Aug 20.

Provincial Key laboratory of Infectious Diseases and Molecular Pathology, Department of Pathology and Pathophysiology, Collaborative and Creative Centre, Shantou University Medical College, Shantou, 515041, Guangdong, China.

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http://dx.doi.org/10.1186/s12885-019-6025-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701116PMC
August 2019

Comprehensive Profiling of Primary and Metastatic ccRCC Reveals a High Homology of the Metastases to a Subregion of the Primary Tumour.

Cancers (Basel) 2019 Jun 12;11(6). Epub 2019 Jun 12.

Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.3390/cancers11060812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628027PMC
June 2019

Systematic Review of the Prognostic Role of the Immune System After Surgery of Colorectal Liver Metastases.

Front Oncol 2019 19;9:148. Epub 2019 Mar 19.

Department of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

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http://dx.doi.org/10.3389/fonc.2019.00148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433783PMC
March 2019

NGS-Based High-Throughput Screen to Identify MicroRNAs Regulating Growth of B-Cell Lymphoma.

Methods Mol Biol 2019 ;1956:269-282

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://link.springer.com/10.1007/978-1-4939-9151-8_12
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http://dx.doi.org/10.1007/978-1-4939-9151-8_12DOI Listing
July 2019

Mutational Evolution in Relapsed Diffuse Large B-Cell Lymphoma.

Cancers (Basel) 2018 Nov 20;10(11). Epub 2018 Nov 20.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.

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http://dx.doi.org/10.3390/cancers10110459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265691PMC
November 2018

Is alectinib the new first line therapy in ALK-rearranged advanced non-small cell lung cancer?

J Thorac Dis 2018 Jul;10(Suppl 18):S2130-S2132

Department of Pulmonary Diseases, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.

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http://jtd.amegroups.com/article/view/22293/17256
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http://dx.doi.org/10.21037/jtd.2018.06.45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072953PMC
July 2018

Argonaute 2 RNA Immunoprecipitation Reveals Distinct miRNA Targetomes of Primary Burkitt Lymphoma Tumors and Normal B Cells.

Am J Pathol 2018 05 17;188(5):1289-1299. Epub 2018 Feb 17.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.01.018DOI Listing
May 2018

Mutations in EMT-Related Genes in ALK Positive Crizotinib Resistant Non-Small Cell Lung Cancers.

Cancers (Basel) 2018 Jan 4;10(1). Epub 2018 Jan 4.

Department of Genetics, University of Groningen, University Medical Centre Groningen, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.3390/cancers10010010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789360PMC
January 2018

Plasmatic miR-210, miR-221 and miR-1233 profile: potential liquid biopsies candidates for renal cell carcinoma.

Oncotarget 2017 Nov 11;8(61):103315-103326. Epub 2017 Oct 11.

Molecular Oncology and Viral Pathology Group, IPO-Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal.

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http://dx.doi.org/10.18632/oncotarget.21733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732730PMC
November 2017

miR-24-3p Is Overexpressed in Hodgkin Lymphoma and Protects Hodgkin and Reed-Sternberg Cells from Apoptosis.

Am J Pathol 2017 Jun 20;187(6):1343-1355. Epub 2017 Apr 20.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.02.016DOI Listing
June 2017

Long Noncoding RNA Expression Profiling in Normal B-Cell Subsets and Hodgkin Lymphoma Reveals Hodgkin and Reed-Sternberg Cell-Specific Long Noncoding RNAs.

Am J Pathol 2016 09 14;186(9):2462-72. Epub 2016 Jul 14.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.05.011DOI Listing
September 2016

Functional Studies on Primary Tubular Epithelial Cells Indicate a Tumor Suppressor Role of SETD2 in Clear Cell Renal Cell Carcinoma.

Neoplasia 2016 06 26;18(6):339-46. Epub 2016 May 26.

Department of Genetics, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2016.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916950PMC
June 2016

SETD2: an epigenetic modifier with tumor suppressor functionality.

Oncotarget 2016 Aug;7(31):50719-50734

Department of Genetics, University of Groningen, University Medical Center Groningen, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.9368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226616PMC
August 2016

Small RNA sequencing reveals a comprehensive miRNA signature of BRCA1-associated high-grade serous ovarian cancer.

J Clin Pathol 2016 Apr 5. Epub 2016 Apr 5.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/jclinpath-2016-203679DOI Listing
April 2016

Long noncoding RNAs as a novel component of the Myc transcriptional network.

FASEB J 2015 Jun 17;29(6):2338-46. Epub 2015 Feb 17.

*Department of Pathology and Medical Biology and Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1096/fj.14-263889DOI Listing
June 2015

Towards sustained silencing of HER2/neu in cancer by epigenetic editing.

Mol Cancer Res 2013 Sep 27;11(9):1029-39. Epub 2013 Jun 27.

University Medical Center Groningen, Groningen, 9713 GZ, the Netherlands.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0567DOI Listing
September 2013

The entire miR-200 seed family is strongly deregulated in clear cell renal cell cancer compared to the proximal tubular epithelial cells of the kidney.

Genes Chromosomes Cancer 2013 Feb 17;52(2):165-73. Epub 2012 Oct 17.

Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/gcc.22016DOI Listing
February 2013

Genome-wide arrays: quality criteria and platforms to be used in routine diagnostics.

Hum Mutat 2012 Jun;33(6):906-15

Laboratory for Cytogenetics and Genome Research, Centre for Human Genetics, KU Leuven, University Hospital Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1002/humu.22076DOI Listing
June 2012

CGH arrays compared for DNA isolated from formalin-fixed, paraffin-embedded material.

Genes Chromosomes Cancer 2012 Apr 8;51(4):344-52. Epub 2011 Dec 8.

Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/gcc.21920DOI Listing
April 2012

Copy number variants on the X chromosome in women with primary ovarian insufficiency.

Fertil Steril 2011 Apr 12;95(5):1584-8.e1. Epub 2011 Feb 12.

Department of Reproductive Medicine and Gynecology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.fertnstert.2011.01.018DOI Listing
April 2011

A chronic obstructive pulmonary disease related signature in squamous cell lung cancer.

Lung Cancer 2011 May 15;72(2):177-83. Epub 2010 Sep 15.

Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.lungcan.2010.08.014DOI Listing
May 2011

Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma.

Cancer Res 2010 Jun 25;70(11):4287-91. Epub 2010 May 25.

Departments of Genetics and Pathology, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-10-0120DOI Listing
June 2010

A high throughput experimental approach to identify miRNA targets in human cells.

Nucleic Acids Res 2009 Nov 4;37(20):e137. Epub 2009 Sep 4.

Department of Pathology and Laboratory Medicine, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkp715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777426PMC
November 2009

Characteristics of dystonia in the 18p deletion syndrome, including a new case.

Clin Neurol Neurosurg 2009 Dec 20;111(10):880-2. Epub 2009 Aug 20.

Department of Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.clineuro.2009.07.013DOI Listing
December 2009

A 649 kb microduplication in 1p34.1, including POMGNT1, in a patient with microcephaly, coloboma and laryngomalacia; and a review of the literature.

Eur J Med Genet 2009 Mar-Jun;52(2-3):116-9

Department of Genetics, CB50, University Medical Centre Groningen, University of Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.ejmg.2009.01.005DOI Listing
September 2009

Genomic aberrations in squamous cell lung carcinoma related to lymph node or distant metastasis.

Lung Cancer 2009 Dec 25;66(3):372-8. Epub 2009 Mar 25.

Department of Pathology & Medical Biology, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.lungcan.2009.02.017DOI Listing
December 2009

Copy number gain at 8q12.1-q22.1 is associated with a malignant tumor phenotype in salivary gland myoepitheliomas.

Genes Chromosomes Cancer 2009 Feb;48(2):202-12

Department of Oral and Maxillofacial Surgery/Oral Pathology, Academic Centre for Dentistry (ACTA), VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/gcc.20631DOI Listing
February 2009

High-resolution mapping identifies a commonly amplified 11q13.3 region containing multiple genes flanked by segmental duplications.

Hum Genet 2007 Apr 15;121(2):187-201. Epub 2006 Dec 15.

Department of Pathology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00439-006-0299-6DOI Listing
April 2007

Global correlation of genome and transcriptome changes in classical Hodgkin lymphoma.

Hematol Oncol 2007 Mar;25(1):21-9

Department of Pathology and Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://doi.wiley.com/10.1002/hon.804
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http://dx.doi.org/10.1002/hon.804DOI Listing
March 2007

Functional analysis of lung tumor suppressor activity at 3p21.3.

Genes Chromosomes Cancer 2006 Dec;45(12):1077-93

Department of Genetics, University Medical Center Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1002/gcc.20367DOI Listing
December 2006

Array comparative genomic hybridization reveals a very high frequency of deletions of the long arm of chromosome 6 in testicular lymphoma.

Genes Chromosomes Cancer 2006 Oct;45(10):976-81

Department of Clinical Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/gcc.20361DOI Listing
October 2006

High expression of calcium-binding proteins, S100A10, S100A11 and CALM2 in anaplastic large cell lymphoma.

Br J Haematol 2005 Dec;131(5):596-608

Department of Pathology and Laboratory Medicine, University Medical Centre Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1111/j.1365-2141.2005.05816.xDOI Listing
December 2005

Application of a comprehensive subtelomere array in clinical diagnosis of mental retardation.

Eur J Med Genet 2005 Jul-Sep;48(3):250-62

Department of Clinical Genetics, University Medical Centre Groningen, Antonius Deusinglaan 4, 9713 AW Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.ejmg.2005.04.007DOI Listing
November 2005