Publications by authors named "Kjeld Schmiegelow"

100Publications

Optimal approach to the treatment of young adults with acute lymphoblastic leukemia in 2020.

Semin Hematol 2020 Jul 28;57(3):102-114. Epub 2020 Aug 28.

Pediatric Oncology Research Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2020.08.001DOI Listing
July 2020

Have COVID-19 affected ALL epidemiology?

Acta Paediatr 2020 Nov 20. Epub 2020 Nov 20.

Paediatrics and Paediatric Oncology, Dept of Paediatrics and Adolescent Medicine, Rigshospitalet University Hospital Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/apa.15631DOI Listing
November 2020

Parent's perspectives of the pathway to diagnosis of childhood cancer: a matter of diagnostic triage.

BMC Health Serv Res 2020 Oct 22;20(1):969. Epub 2020 Oct 22.

Department of Paediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1186/s12913-020-05821-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584100PMC
October 2020

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia.

Cochrane Database Syst Rev 2020 10 10;10:CD013399. Epub 2020 Oct 10.

Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/14651858.CD013399.pub2DOI Listing
October 2020

Radio-Resistance and DNA Repair in Pediatric Diffuse Midline Gliomas.

Cancers (Basel) 2020 Sep 30;12(10). Epub 2020 Sep 30.

Brain Tumor Biology, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.3390/cancers12102813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600397PMC
September 2020

[Træthed hos patienter, der er helbredt for kræft i barnealderen].

Ugeskr Laeger 2020 Aug;182(36)

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August 2020

Management of Asparaginase Toxicity in AYAs with ALL.

Clin Lymphoma Myeloma Leuk 2020 Sep;20 Suppl 1:S12-S13

Department of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Blegdamsvej 9, Copenhagen, 2100, Denmark.

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http://dx.doi.org/10.1016/S2152-2650(20)30444-4DOI Listing
September 2020

Cationic amphiphilic drugs induce elevation in lysoglycerophospholipid levels and cell death in leukemia cells.

Metabolomics 2020 08 26;16(9):91. Epub 2020 Aug 26.

Cell Death and Metabolism Unit, Center for Autophagy, Recycling and Disease (CARD), Danish Cancer Society Research Center (DCRC), 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s11306-020-01710-1DOI Listing
August 2020

Maintenance therapy of childhood acute lymphoblastic leukemia: Do all roads lead to Rome?

Pediatr Blood Cancer 2020 Aug 15:e28418. Epub 2020 Aug 15.

Department of Pediatrics and Adolescent Medicine, The University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/pbc.28418DOI Listing
August 2020

Smartphone App to Self-Monitor Nausea During Pediatric Chemotherapy Treatment: User-Centered Design Process.

JMIR Mhealth Uhealth 2020 07 20;8(7):e18564. Epub 2020 Jul 20.

Department of Clinical Pharmacology, Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.2196/18564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400028PMC
July 2020

Acute lymphoblastic leukemia and down syndrome: 6-mercaptopurine and methotrexate metabolites during maintenance therapy.

Leukemia 2020 Jul 4. Epub 2020 Jul 4.

Department of Pediatrics and Adolescent Medicine, The Juliane Marie Centre, The University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41375-020-0946-2DOI Listing
July 2020

Feasibility and Validity of the Actiheart Activity Monitor in Children Who Were Hospitalized With Cancer Coadmitted With Classmates: A RESPECT Study.

Pediatr Phys Ther 2020 07;32(3):226-233

Departments of Pediatrics and Adolescent Medicine (Mr Schmidt-Andersen, Drs Mogensen, Schmiegelow, and Larsen and Mr Nielsen) and Diabetes and Metabolism (Dr Mogensen), Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark; Faculty of Health Science, University of Copenhagen, (Drs Moeller and Schmiegelow and Mr Nielsen), Copenhagen, Denmark; The University Hospitals Centre for Health Research (UCSF) (Dr Møller), Copenhagen, Denmark.

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http://dx.doi.org/10.1097/PEP.0000000000000712DOI Listing
July 2020

Pharmacokinetics of tablet and liquid formulations of oral 6-mercaptopurine in children with acute lymphoblastic leukemia.

Cancer Chemother Pharmacol 2020 Jul 9;86(1):25-32. Epub 2020 Jun 9.

Department of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00280-020-04097-xDOI Listing
July 2020

Feasibility of monitoring peripheral blood to detect emerging clones in children with acute lymphoblastic leukemia.

Pediatr Blood Cancer 2020 07 11;67(7):e28306. Epub 2020 May 11.

Department of Pediatrics, Perlmutter Cancer Center, NYU Langone Health, New York.

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http://dx.doi.org/10.1002/pbc.28306DOI Listing
July 2020

Pharmacogenetics of antiemetics for chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis.

Crit Rev Oncol Hematol 2020 May 4;149:102939. Epub 2020 Apr 4.

Department of Paediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2020.102939DOI Listing
May 2020

Gastrointestinal toxicity during induction treatment for childhood acute lymphoblastic leukemia: The impact of the gut microbiota.

Int J Cancer 2020 Oct 16;147(7):1953-1962. Epub 2020 Mar 16.

Department of Paediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/ijc.32942DOI Listing
October 2020

Minimal residual disease monitoring cannot fully replace bone marrow morphology in assessing disease status in pediatric acute lymphoblastic leukemia.

APMIS 2020 May 25;128(5):414-419. Epub 2020 Mar 25.

Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark.

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http://dx.doi.org/10.1111/apm.13037DOI Listing
May 2020

Parental occupational organic dust exposure and selected childhood cancers in Denmark 1968-2016.

Cancer Epidemiol 2020 04 17;65:101667. Epub 2020 Jan 17.

Danish Cancer Society Research Centre, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.canep.2020.101667DOI Listing
April 2020

Candidate single nucleotide polymorphisms and thromboembolism in acute lymphoblastic leukemia - A NOPHO ALL2008 study.

Thromb Res 2019 Dec 7;184:92-98. Epub 2019 Nov 7.

Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University Hospital of Copenhagen, Belgdamsvej 9, 2100 Copenhagen, Denmark; Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Nørregade 10, 1165 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.thromres.2019.11.002DOI Listing
December 2019

A European paediatric cancer mission: aspiration or reality?

Lancet Oncol 2019 09;20(9):1200-1202

Department of Pediatrics and Adolescent Medicine, Rigshospitalet University Hospital, and Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/S1470-2045(19)30487-5DOI Listing
September 2019

The preleukemic TCF3-PBX1 gene fusion can be generated in utero and is present in ≈0.6% of healthy newborns.

Blood 2019 10;134(16):1355-1358

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1182/blood.2019002215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005361PMC
October 2019

End-of-life communication: a nationwide study of bereaved parents' perceptions.

BMJ Support Palliat Care 2019 Jul 11. Epub 2019 Jul 11.

Department of Oncology, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1136/bmjspcare-2018-001709DOI Listing
July 2019

Anxiety and Depression in Bereaved Parents After Losing a Child due to Life-Limiting Diagnoses: A Danish Nationwide Questionnaire Survey.

J Pain Symptom Manage 2019 10 2;58(4):596-604. Epub 2019 Jul 2.

Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jpainsymman.2019.06.025DOI Listing
October 2019

Classmates motivate childhood cancer patients to participate in physical activity during treatment: A qualitative study.

Eur J Cancer Care (Engl) 2019 Sep 18;28(5):e13121. Epub 2019 Jun 18.

Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital (Rigshospitalet), Copenhagen Ø, Denmark.

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http://dx.doi.org/10.1111/ecc.13121DOI Listing
September 2019

Unmet need for interprofessional education in paediatric cancer: a scoping review.

Support Care Cancer 2019 Oct 24;27(10):3627-3637. Epub 2019 May 24.

Juliane Marie Centre for Children, Women and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00520-019-04856-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726701PMC
October 2019

Social Inequalities Along the Childhood Cancer Continuum: An Overview of Evidence and a Conceptual Framework to Identify Underlying Mechanisms and Pathways.

Front Public Health 2019 18;7:84. Epub 2019 Apr 18.

Department of Prevention and Evaluation, Leibniz - Institute for Prevention Research and Epidemiology - BIPS GmbH, Bremen, Germany.

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http://dx.doi.org/10.3389/fpubh.2019.00084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492628PMC
April 2019

Bovine Colostrum Against Chemotherapy-Induced Gastrointestinal Toxicity in Children With Acute Lymphoblastic Leukemia: A Randomized, Double-Blind, Placebo-Controlled Trial.

JPEN J Parenter Enteral Nutr 2020 02 12;44(2):337-347. Epub 2019 Mar 12.

Department of Paediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/jpen.1528DOI Listing
February 2020

Risk of selected childhood cancers and parental employment in painting and printing industries: A register-based case‒control study in Denmark 1968-2015.

Scand J Work Environ Health 2019 09 6;45(5):475-482. Epub 2019 Mar 6.

The Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen Ø, Denmark.

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http://dx.doi.org/10.5271/sjweh.3811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717518PMC
September 2019

Yet another susceptibility variant for ALL: what's next?

Blood 2019 02;133(7):628-629

University of Copenhagen.

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http://dx.doi.org/10.1182/blood-2018-12-891564DOI Listing
February 2019

Maternal use of hormonal contraception and risk of childhood leukaemia - Authors' reply.

Lancet Oncol 2018 12;19(12):e659

Virus, Lifestyle and Genes, Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark; Department of Gynaecology, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/S1470-2045(18)30849-0DOI Listing
December 2018

Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy.

Cancer Chemother Pharmacol 2019 01 15;83(1):53-60. Epub 2018 Oct 15.

Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark.

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http://link.springer.com/10.1007/s00280-018-3704-7
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http://dx.doi.org/10.1007/s00280-018-3704-7DOI Listing
January 2019

Insulin-dependent diabetes: A chronic complication to acute pancreatitis in childhood acute lymphoblastic leukemia.

Pediatr Blood Cancer 2019 01 14;66(1):e27437. Epub 2018 Sep 14.

Department of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/pbc.27437DOI Listing
January 2019

Maternal use of hormonal contraception and risk of childhood leukaemia: a nationwide, population-based cohort study.

Lancet Oncol 2018 10 6;19(10):1307-1314. Epub 2018 Sep 6.

Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark; Department of Gynaecology, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/S1470-2045(18)30479-0DOI Listing
October 2018

Putative new childhood leukemia cancer predisposition syndrome caused by germline bi-allelic missense mutations in DDX41.

Genes Chromosomes Cancer 2018 12 11;57(12):670-674. Epub 2018 Oct 11.

Department of Clinical Genetics, University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/gcc.22680DOI Listing
December 2018

Pediatric cancer families' participation in whole-genome sequencing research in Denmark: Parent perspectives.

Eur J Cancer Care (Engl) 2018 Nov 17;27(6):e12877. Epub 2018 Jul 17.

Department of Anthropology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/ecc.12877DOI Listing
November 2018

The cost of cure.

Lancet Haematol 2018 Nov 12;5(11):e504-e505. Epub 2018 Jun 12.

Department of Paediatrics and Adolescent Medicine, Juliane Marie Centre, Righospitalet University Hospital, Copenhagen 2100, Denmark.

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http://dx.doi.org/10.1016/S2352-3026(18)30070-XDOI Listing
November 2018

Testing physical function in children undergoing intense cancer treatment-a RESPECT feasibility study.

Pediatr Blood Cancer 2018 08 9;65(8):e27100. Epub 2018 May 9.

Department of Pediatrics and Adolescent Medicine, The Juliane Marie Center, University Hospital (Rigshospitalet), Copenhagen, Denmark.

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http://doi.wiley.com/10.1002/pbc.27100
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http://dx.doi.org/10.1002/pbc.27100DOI Listing
August 2018

Socioeconomic Factors and Ninth Grade School Performance in Childhood Leukemia and CNS Tumor Survivors.

JNCI Cancer Spectr 2018 Jan 25;2(1):pky003. Epub 2018 Apr 25.

Unit of Statistics, Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1093/jncics/pky003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649790PMC
January 2018

Association between body mass index and pancreatitis in children with acute lymphoblastic leukemia.

Pediatr Blood Cancer 2018 08 18;65(8):e27071. Epub 2018 Apr 18.

Department of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/pbc.27071DOI Listing
August 2018

All-cause mortality rates and home deaths decreased in children with life-limiting diagnoses in Denmark between 1994 and 2014.

Acta Paediatr 2018 10 19;107(10):1781-1785. Epub 2018 Apr 19.

Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/apa.14331DOI Listing
October 2018

Role of TPMT and ITPA variants in mercaptopurine disposition.

Cancer Chemother Pharmacol 2018 03 1;81(3):579-586. Epub 2018 Feb 1.

Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.

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http://link.springer.com/10.1007/s00280-018-3525-8
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http://dx.doi.org/10.1007/s00280-018-3525-8DOI Listing
March 2018

Five percent of healthy newborns have an fusion as revealed by DNA-based GIPFEL screening.

Blood 2018 02 8;131(7):821-826. Epub 2018 Jan 8.

Department of Pediatric Oncology, Hematology, and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

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http://dx.doi.org/10.1182/blood-2017-09-808402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909885PMC
February 2018

A Role for Thiopurine Metabolites in the Synergism Between Thiopurines and Infliximab in Inflammatory Bowel Disease.

J Crohns Colitis 2018 Feb;12(3):298-305

Department of Gastroenterology, Copenhagen University Hospital, Herlev, Denmark.

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http://dx.doi.org/10.1093/ecco-jcc/jjx149DOI Listing
February 2018

Maternal diabetes and risk of childhood acute lymphoblastic leukaemia in the offspring.

Br J Cancer 2018 01 3;118(1):117-120. Epub 2017 Oct 3.

Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.

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http://dx.doi.org/10.1038/bjc.2017.351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765219PMC
January 2018

Survival from tumours of the central nervous system in Danish children: Is survival related to family circumstances?

Int J Cancer 2018 02 16;142(4):671-680. Epub 2017 Oct 16.

Section of Environment and Radiation, International Agency for Research on Cancer (IARC), 150 Cours Albert Thomas, Lyon, 69372, France.

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http://dx.doi.org/10.1002/ijc.31082DOI Listing
February 2018

Youth friendly communication in a transition clinic aimed at adolescents with chronic illness.

Int J Adolesc Med Health 2017 Aug 29;32(1). Epub 2017 Aug 29.

Zealand University Hospital & The Research Unit for General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1515/ijamh-2017-0083DOI Listing
August 2017