Publications by authors named "Kirsten Reichmuth"

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Antiretroviral regimens containing a single protease inhibitor increase risk of virologic failure in young HIV-infected children.

Pediatr Infect Dis J 2013 Apr;32(4):361-3

Department of Paediatrics and Child Health, Desmond Tutu TB Centre, Stellenbosch University, South Africa.

Rifampin-based tuberculosis treatment can cause subtherapeutic concentrations of protease inhibitors and virologic failure in children receiving antiretroviral therapy. Among 217 children on antiretroviral therapy, tuberculosis cotreatment (in 78) was associated with virologic failure. Ritonavir-based single protease inhibitor antiretroviral therapy regimen predicted virologic failure (adjusted odds ratio 3.7, 95% confidence interval 1.5-8.9, P = 0.004) on multivariate analysis.
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http://dx.doi.org/10.1097/INF.0b013e318279c800DOI Listing
April 2013
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