Kirsten Leineweber

Kirsten Leineweber

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Kirsten Leineweber

Kirsten Leineweber

Publications by authors named "Kirsten Leineweber"

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Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Genetics of NO Deficiency.

Am J Cardiol 2017 Oct;120(8S):S80-S88

Bayer AG, Whippany, New Jersey.

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http://dx.doi.org/10.1016/j.amjcard.2017.06.013DOI Listing
October 2017

Androgen inhibits key atherosclerotic processes by directly activating ADTRP transcription.

Biochim Biophys Acta Mol Basis Dis 2017 09 20;1863(9):2319-2332. Epub 2017 Jun 20.

Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Center for Human Genome Research, Cardio-Institute, Huazhong University of Science and Technology, Wuhan 430074, PR China; Center for Cardiovascular Genetics, Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH 44195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859308PMC
September 2017

Novel pathomechanisms of cardiomyocyte dysfunction in a model of heart failure with preserved ejection fraction.

Eur J Heart Fail 2016 08 2;18(8):987-97. Epub 2016 May 2.

Department of Cardiology, Charité University Medicine Berlin, Campus Virchow-Klinikum, Berlin, Germany.

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http://dx.doi.org/10.1002/ejhf.524DOI Listing
August 2016

Coronary atherosclerosis burden, but not transient troponin elevation, predicts long-term outcome in recreational marathon runners.

Basic Res Cardiol 2014 Jan 19;109(1):391. Epub 2013 Nov 19.

Clinic of Cardiology and Intensive Care Medicine, Bethanien Hospital Moers, Bethanienstrasse 21, 47441, Moers, Germany,

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http://dx.doi.org/10.1007/s00395-013-0391-8DOI Listing
January 2014

Mechanical load-dependent cardiac ER stress in vitro and in vivo: effects of preload and afterload.

FEBS Lett 2012 May 12;586(9):1363-9. Epub 2012 Apr 12.

Department of Cardiology and Pneumology, Georg-August-University, Goettingen, Germany.

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http://dx.doi.org/10.1016/j.febslet.2012.03.055DOI Listing
May 2012

Partial adenosine A1 receptor agonists for cardiovascular therapies.

Purinergic Signal 2012 Feb 12;8(Suppl 1):91-9. Epub 2011 Nov 12.

Research Center Wuppertal, Department of Heart Diseases, Institute of Cardiology, Bayer Pharma AG, Aprather Weg 18a, 42096, Wuppertal, Germany,

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http://dx.doi.org/10.1007/s11302-011-9274-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265704PMC
February 2012

The Arg16Gly-β(2)-adrenoceptor single nucleotide polymorphism: exercise capacity and survival in patients with end-stage heart failure.

Naunyn Schmiedebergs Arch Pharmacol 2010 Oct 29;382(4):357-65. Epub 2010 Aug 29.

Institute for Pathophysiology, University of Duisburg-Essen School of Medicine, Essen, Germany.

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http://dx.doi.org/10.1007/s00210-010-0548-zDOI Listing
October 2010

Imatinib ameliorates fibrosis in uraemic cardiac disease in BALB/c without improving cardiac function.

Nephrol Dial Transplant 2010 Jun 7;25(6):1817-24. Epub 2010 Jan 7.

Department of Nephrology, Klinikum rechts der Isar, Technische Universität München, Germany.

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http://dx.doi.org/10.1093/ndt/gfp708DOI Listing
June 2010

Serotoninergic and non-serotoninergic effects of two tricyclic antidepressants on visceral nociception in a rat model.

Scand J Gastroenterol 2009 ;44(6):680-6

Department of Gastroenterology, University of Essen, Germany.

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http://dx.doi.org/10.1080/00365520902767272DOI Listing
October 2009

Beta 1- and beta 2-adrenoceptor polymorphisms and cardiovascular diseases.

Br J Pharmacol 2009 Sep 5;158(1):61-9. Epub 2009 May 5.

Institute for Pathophysiology, University of Essen, School of Medicine, Essen, Germany.

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http://dx.doi.org/10.1111/j.1476-5381.2009.00187.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795234PMC
September 2009

Methods to evaluate the pharmacology of oral antiplatelet drugs.

Herz 2008 Jun;33(4):287-96

Institute of Pharmacology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s00059-008-3132-2DOI Listing
June 2008

Regulation and role of the presynaptic and myocardial Na+/H+ exchanger NHE1: effects on the sympathetic nervous system in heart failure.

Cardiovasc Drug Rev 2007 ;25(2):123-31

Institute of Pathophysiology, University of Essen School of Medicine, D-45122 Essen, Germany.

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http://dx.doi.org/10.1111/j.1527-3466.2007.00010.xDOI Listing
August 2007

In patients chronically treated with metoprolol, the demand of inotropic catecholamine support after coronary artery bypass grafting is determined by the Arg389Gly-beta 1-adrenoceptor polymorphism.

Naunyn Schmiedebergs Arch Pharmacol 2007 Jul 1;375(5):303-9. Epub 2007 Jun 1.

Department of Pathophysiology and Nephrology, University of Essen School of Medicine, Hufelandstr. 55, 45147, Essen, Germany.

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http://dx.doi.org/10.1007/s00210-007-0166-6DOI Listing
July 2007

Release of TNF-alpha during stent implantation into saphenous vein aortocoronary bypass grafts and its relation to plaque extrusion and restenosis.

Am J Physiol Heart Circ Physiol 2007 May 5;292(5):H2295-9. Epub 2007 Jan 5.

Department of Cardiology, University of Essen Medical School, Hufelandstrasse 55, 45147 Essen, Germany.

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http://dx.doi.org/10.1152/ajpheart.01116.2006DOI Listing
May 2007

CaMKII-mediated increased lusitropic responses to beta-adrenoreceptor stimulation in ANP-receptor deficient mice.

Cardiovasc Res 2007 Mar 7;73(4):678-88. Epub 2006 Oct 7.

Institute of Physiology, University of Würzburg, Röntgenring 9, D-97070 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2006.10.003DOI Listing
March 2007

Cardiac adrenoceptors: physiological and pathophysiological relevance.

J Pharmacol Sci 2006 13;100(5):323-37. Epub 2006 Apr 13.

Department of Pathophysiology, University of Essen School of Medicine, Germany.

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http://dx.doi.org/10.1254/jphs.crj06001xDOI Listing
August 2006

Intense vasoconstriction in response to aspirate from stented saphenous vein aortocoronary bypass grafts.

J Am Coll Cardiol 2006 Mar 9;47(5):981-6. Epub 2006 Feb 9.

Institute of Pathophysiology, University of Essen School of Medicine, Essen, Germany.

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http://dx.doi.org/10.1016/j.jacc.2005.10.053DOI Listing
March 2006

The Arg389Gly beta1-adrenoceptor polymorphism does not affect cardiac effects of exercise after parasympathetic inhibition by atropine.

Pharmacogenet Genomics 2006 Jan;16(1):9-13

Department of Nephrology, University of Essen Medical School, Germany.

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January 2006

The Arg389Gly beta1-adrenoceptor polymorphism and catecholamine effects on plasma-renin activity.

J Am Coll Cardiol 2005 Dec 4;46(11):2111-5. Epub 2005 Nov 4.

Department of Nephrology, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1016/j.jacc.2005.08.041DOI Listing
December 2005

Human beta2-adrenergic receptor gene haplotypes and venodilation in vivo.

Clin Pharmacol Ther 2005 Sep;78(3):232-8

Department of Nephrology and Pathophysiology, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1016/j.clpt.2005.06.002DOI Listing
September 2005

G-protein-coupled receptor kinase activity in human heart failure: effects of beta-adrenoceptor blockade.

Cardiovasc Res 2005 Jun 7;66(3):512-9. Epub 2005 Apr 7.

Department of Pathophysiology, University of Essen School of Medicine, Germany.

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http://dx.doi.org/10.1016/j.cardiores.2005.01.025DOI Listing
June 2005

Beta2-adrenoceptor gene polymorphisms.

Pharmacogenet Genomics 2005 May;15(5):267-75

Department of Pathophysiology, University of Essen School of Medicine; D-45147 Essen/Germany.

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May 2005

Beta-adrenergic receptor polymorphism in human cardiovascular disease.

Ann Med 2004 ;36 Suppl 1:64-9

Department of Pathophysiology, University of Essen Medical School, Hufelandstr. 55, D-45147 Essen, Germany.

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http://dx.doi.org/10.1080/17431380410032544DOI Listing
October 2004

Autonomic receptor systems in the failing and aging human heart: similarities and differences.

Eur J Pharmacol 2004 Oct;500(1-3):167-76

Departments of Pathophysiology and Nephrology, University of Essen School of Medicine, IG I., 9.OG, Hufelandstr. 55, D-45147 Essen, Germany.

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http://dx.doi.org/10.1016/j.ejphar.2004.07.022DOI Listing
October 2004

Beta2-adrenoceptor polymorphisms: relation between in vitro and in vivo phenotypes.

Life Sci 2004 Apr;74(23):2803-14

Departments of Pathophysiology and Nephrology, University of Essen School of Medicine, IG I., 9.OG, Hufelandstr. 55, D-45147, Essen, Germany.

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http://dx.doi.org/10.1016/j.lfs.2003.10.025DOI Listing
April 2004

Thr164Ile polymorphism of the human beta2-adrenoceptor exhibits blunted desensitization of cardiac functional responses in vivo.

Am J Physiol Heart Circ Physiol 2003 Nov 17;285(5):H2034-8. Epub 2003 Jul 17.

Departments of Pathophysiology and Nephrology, University of Essen Medical School, Hufelandstrasse 55, D-45147 Essen, Germany.

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http://www.physiology.org/doi/10.1152/ajpheart.00324.2003
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http://dx.doi.org/10.1152/ajpheart.00324.2003DOI Listing
November 2003

Existence of functional M3-muscarinic receptors in the human heart.

Naunyn Schmiedebergs Arch Pharmacol 2003 Oct 1;368(4):316-9. Epub 2003 Oct 1.

Institute of Pharmacology, University of Halle, 06097 Halle, Germany.

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http://dx.doi.org/10.1007/s00210-003-0796-2DOI Listing
October 2003

Unchanged G-protein-coupled receptor kinase activity in the aging human heart.

J Am Coll Cardiol 2003 Oct;42(8):1487-92

Departments of Pathophysiology and Nephrology, University of Essen School of Medicine, Essen, Germany

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http://dx.doi.org/10.1016/s0735-1097(03)01063-5DOI Listing
October 2003

Genotype-dependent time course of lymphocyte beta 2-adrenergic receptor down-regulation.

Clin Pharmacol Ther 2003 Sep;74(3):255-63

Department of Pathophysiology and Nephrology, University of Essen Medical School, Germany.

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http://dx.doi.org/10.1016/S0009-9236(03)00188-7DOI Listing
September 2003

Mechanical load-dependent regulation of gene expression in monocrotaline-induced right ventricular hypertrophy in the rat.

Circ Res 2003 Aug 3;93(3):230-7. Epub 2003 Jul 3.

Georg-August-Universität Göttingen, Abteilung Kardiologie und Pneumologie, Robert-Koch-Str. 40, D-37075 Göttingen, Germany.

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http://dx.doi.org/10.1161/01.RES.0000085042.89656.C7DOI Listing
August 2003

The Gln27Glu beta2-adrenoceptor polymorphism slows the onset of desensitization of cardiac functional responses in vivo.

Pharmacogenetics 2003 Feb;13(2):59-66

Institute of Pharmacology, University of Halle, Germany.

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February 2003

Changes in alpha(1)-adrenergic vascular reactivity in monocrotaline-treated rats.

Naunyn Schmiedebergs Arch Pharmacol 2002 Feb 20;365(2):87-95. Epub 2001 Dec 20.

Institute of Pharmacology, University of Halle-Wittenberg, Magdeburger Strasse 4, 06097 Halle/Saale, Germany.

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http://dx.doi.org/10.1007/s00210-001-0515-9DOI Listing
February 2002

Cardiac beta-adrenoceptor desensitization due to increased beta-adrenoceptor kinase activity in chronic uremia.

J Am Soc Nephrol 2002 Jan;13(1):117-24

Institute of Pharmacology and Toxicology, Martin-Luther-University of Halle-Wittenberg, Halle, Germany.

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January 2002