Kirsi Pietilainen

Kirsi Pietilainen

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Kirsi Pietilainen

Publications by authors named "Kirsi Pietilainen"

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Role of apolipoprotein C-III overproduction in diabetic dyslipidaemia.

Diabetes Obes Metab 2019 Aug 8;21(8):1861-1870. Epub 2019 May 8.

Department of Molecular and Clinical Medicine, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/dom.13744DOI Listing
August 2019

Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs.

Proteomics Clin Appl 2019 Jul 5;13(4):e1800173. Epub 2019 Feb 5.

Obesity Research Unit, Research Programs Unit, Diabetes and Obesity Research Program, University of Helsinki, 00014, Helsinki, Finland.

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http://dx.doi.org/10.1002/prca.201800173DOI Listing
July 2019

Short Sleep Duration and Later Overweight in Infants.

J Pediatr 2019 Jun 14. Epub 2019 Jun 14.

Pediatric Research Center, Child Psychiatry, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jpeds.2019.05.041DOI Listing
June 2019

Mechanisms of early glucose regulation disturbance after out-of-hospital cardiopulmonary resuscitation: An explorative prospective study.

PLoS One 2019 25;14(3):e0214209. Epub 2019 Mar 25.

Department of Emergency Medicine and Services, Helsinki University and Helsinki University Hospital, Helsinki, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214209PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433228PMC
March 2019

Increased body fat mass and androgen metabolism - A twin study in healthy young women.

Steroids 2018 12 25;140:24-31. Epub 2018 Aug 25.

University of Helsinki, Research Programs Unit, Diabetes and Obesity, Obesity Research Unit, P.O. Box 63, 00014 University of Helsinki, Finland; Helsinki University Hospital, Endocrinology, Abdominal Center, P.O. Box 340, 00029 HUS, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.steroids.2018.08.006DOI Listing
December 2018

Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts.

Biol Sex Differ 2017 27;8:14. Epub 2017 Apr 27.

Institute for Molecular Medicine FIMM, University of Helsinki, P.O. Box 20, FI-00014 Helsinki, Finland.

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http://dx.doi.org/10.1186/s13293-017-0134-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408365PMC
June 2018

Is preoperative gastroscopy necessary before sleeve gastrectomy and Roux-en-Y gastric bypass?

Surg Obes Relat Dis 2018 06 14;14(6):757-762. Epub 2018 Feb 14.

Helsinki University Hospital, Abdominal Center, Department of Gastrointestinal Surgery, helsinki, Finland.

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http://dx.doi.org/10.1016/j.soard.2018.01.021DOI Listing
June 2018

Associations between birth size and later height from infancy through adulthood: An individual based pooled analysis of 28 twin cohorts participating in the CODATwins project.

Early Hum Dev 2018 05 12;120:53-60. Epub 2018 Apr 12.

Department of Social Research, University of Helsinki, Helsinki, Finland; Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.earlhumdev.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532975PMC
May 2018

Association between birthweight and later body mass index: an individual-based pooled analysis of 27 twin cohorts participating in the CODATwins project.

Int J Epidemiol 2017 10;46(5):1488-1498

Department of Social Research, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1093/ije/dyx031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837357PMC
October 2017

Metabolism of sex steroids is influenced by acquired adiposity-A study of young adult male monozygotic twin pairs.

J Steroid Biochem Mol Biol 2017 09 13;172:98-105. Epub 2017 Jun 13.

University of Helsinki, Research Programs Unit, Diabetes and Obesity, Obesity Research Unit, P.O. Box 63, 00014, University of Helsinki, Finland; Helsinki University Hospital, Endocrinology, Abdominal Center, P.O. Box 340, 00029 HUS, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jsbmb.2017.06.007DOI Listing
September 2017

Adipose tissue NAD-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health.

Redox Biol 2017 08 27;12:246-263. Epub 2017 Feb 27.

Molecular Neurology, Research Programs Unit, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2017.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343002PMC
August 2017

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts.

Authors:
Karri Silventoinen Aline Jelenkovic Reijo Sund Yoshie Yokoyama Yoon-Mi Hur Wendy Cozen Amie E Hwang Thomas M Mack Chika Honda Fujio Inui Yoshinori Iwatani Mikio Watanabe Rie Tomizawa Kirsi H Pietiläinen Aila Rissanen Sisira H Siribaddana Matthew Hotopf Athula Sumathipala Fruhling Rijsdijk Qihua Tan Dongfeng Zhang Zengchang Pang Maarit Piirtola Sari Aaltonen Sevgi Y Öncel Fazil Aliev Esther Rebato Jacob B Hjelmborg Kaare Christensen Axel Skytthe Kirsten O Kyvik Judy L Silberg Lindon J Eaves Tessa L Cutler Juan R Ordoñana Juan F Sánchez-Romera Lucia Colodro-Conde Yun-Mi Song Sarah Yang Kayoung Lee Carol E Franz William S Kremen Michael J Lyons Andreas Busjahn Tracy L Nelson Keith E Whitfield Christian Kandler Kerry L Jang Margaret Gatz David A Butler Maria A Stazi Corrado Fagnani Cristina D'Ippolito Glen E Duncan Dedra Buchwald Nicholas G Martin Sarah E Medland Grant W Montgomery Hoe-Uk Jeong Gary E Swan Ruth Krasnow Patrik Ke Magnusson Nancy L Pedersen Anna K Dahl Aslan Tom A McAdams Thalia C Eley Alice M Gregory Per Tynelius Laura A Baker Catherine Tuvblad Gombojav Bayasgalan Danshiitsoodol Narandalai Timothy D Spector Massimo Mangino Genevieve Lachance S Alexandra Burt Kelly L Klump Jennifer R Harris Ingunn Brandt Thomas S Nilsen Robert F Krueger Matt McGue Shandell Pahlen Robin P Corley Brooke M Huibregtse Meike Bartels Catharina Em van Beijsterveldt Gonneke Willemsen Jack H Goldberg Finn Rasmussen Adam D Tarnoki David L Tarnoki Catherine A Derom Robert F Vlietinck Ruth Jf Loos John L Hopper Joohon Sung Hermine H Maes Eric Turkheimer Dorret I Boomsma Thorkild Ia Sørensen Jaakko Kaprio

Am J Clin Nutr 2017 Aug 5;106(2):457-466. Epub 2017 Jul 5.

Public Health, and.

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http://dx.doi.org/10.3945/ajcn.117.153643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525120PMC
August 2017

Cardiorespiratory Fitness and Adiposity as Determinants of Metabolic Health-Pooled Analysis of Two Twin Cohorts.

J Clin Endocrinol Metab 2017 05;102(5):1520-1528

Obesity Research Unit, Research Programs Unit, Diabetes and Obesity, University of Helsinki, 00290 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2016-3435DOI Listing
May 2017

Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins.

Diabetologia 2017 01 12;60(1):169-181. Epub 2016 Oct 12.

Obesity Research Unit, Research Programs Unit, Diabetes and Obesity, University of Helsinki, Biomedicum Helsinki, C424b, P.O. Box 63, Haartmaninkatu 8, 00014, Helsinki, Finland.

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http://dx.doi.org/10.1007/s00125-016-4121-2DOI Listing
January 2017

Association of MMP-8 with obesity, smoking and insulin resistance.

Eur J Clin Invest 2016 Sep;46(9):757-65

Cancer and Translational Medicine Research Unit, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1111/eci.12649DOI Listing
September 2016

Deep subcutaneous adipose tissue lipid unsaturation associates with intramyocellular lipid content.

Metabolism 2016 Sep 24;65(9):1230-7. Epub 2016 May 24.

FIMM, Institute for Molecular Medicine, University of Helsinki, Helsinki 00014, Finland; Obesity Research Unit, Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki 00014, Finland; Endocrinology, Abdominal Center, Helsinki University Central Hospital and University of Helsinki, Helsinki 00290, Finland.

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http://dx.doi.org/10.1016/j.metabol.2016.05.010DOI Listing
September 2016

Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue.

J Clin Endocrinol Metab 2016 Mar 13;101(3):1263-73. Epub 2016 Jan 13.

Obesity Research Unit (E.R., S.J., S.K., S.H., A.R., K.H.P.), Research Programs Unit, University of Helsinki, 00014 Helsinki, Finland; Research Program for Molecular Neurology (R.R.-T., E.P.), University of Helsinki, 00014 Helsinki, Finland; Helsinki Medical Imaging Center (A.H., J.L., N.L.), Radiology, University of Helsinki, 00290 Helsinki, Finland; Institute for Clinical Diabetology (J.L.), German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University, 40225 Düsseldorf, Germany; Turku Positron Emission Tomography Center (V.S., K.A.V.), Turku University Hospital and University of Turku, 20521 Turku, Finland; Institute for Molecular Medicine Finland (K.H.P.), Institute for Molecular Medicine Finland, University of Helsinki, 00014 Helsinki, Finland; Endocrinology (K.H.P.), Abdominal Center, Helsinki University Hospital, University of Helsinki, 00014 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2015-3054DOI Listing
March 2016

Abdominal obesity and circulating metabolites: A twin study approach.

Metabolism 2016 Mar 31;65(3):111-21. Epub 2015 Oct 31.

Obesity Research Unit, Research programs unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland; Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.metabol.2015.10.027DOI Listing
March 2016

Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins.

J Clin Endocrinol Metab 2016 Jan 17;101(1):275-83. Epub 2015 Nov 17.

Obesity Research Unit, Research Programs Unit, Diabetes and Obesity (S.J., S.H., J.T.R., E.R., M.T., M.M., A.R., K.H.P.), FIMM, Institute for Molecular Medicine Finland, (J.T.R., J.K., K.H.P.), Molecular Neurology, Research Programs Unit (R.R.T., E.P.), University of Helsinki, Helsinki, Finland, and Helsinki Medical Imaging Center, Radiology (A.H., N.L.), University of Helsinki, Biomedicum Helsinki, Helsinki, Finland 00014; Institute for Clinical Diabetology, German Diabetes Center (J.L.), Leibniz Center for Diabetes Research, Heinrich Heine University, Düsseldorf, Germany; Finnish Twin Cohort Study, Department of Public Health (J.K.), and Department of Health (J.K.), National Institute for Health and Welfare, Helsinki, Finland; and Department of Endocrinology, Abdominal Center (K.H.P.), Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland 00014.

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http://dx.doi.org/10.1210/jc.2015-3095DOI Listing
January 2016

Impaired Mitochondrial Biogenesis in Adipose Tissue in Acquired Obesity.

Diabetes 2015 Sep 13;64(9):3135-45. Epub 2015 May 13.

Obesity Research Unit, Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland Abdominal Center, Endocrinology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland

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http://diabetes.diabetesjournals.org/content/early/2015/05/1
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http://diabetes.diabetesjournals.org/content/64/9/3135.full.
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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db14
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http://dx.doi.org/10.2337/db14-1937DOI Listing
September 2015

Directional dominance on stature and cognition in diverse human populations.

Authors:
Peter K Joshi Tonu Esko Hannele Mattsson Niina Eklund Ilaria Gandin Teresa Nutile Anne U Jackson Claudia Schurmann Albert V Smith Weihua Zhang Yukinori Okada Alena Stančáková Jessica D Faul Wei Zhao Traci M Bartz Maria Pina Concas Nora Franceschini Stefan Enroth Veronique Vitart Stella Trompet Xiuqing Guo Daniel I Chasman Jeffery R O'Connel Tanguy Corre Suraj S Nongmaithem Yuning Chen Massimo Mangino Daniela Ruggiero Michela Traglia Aliki-Eleni Farmaki Tim Kacprowski Andrew Bjonnes Ashley van der Spek Ying Wu Anil K Giri Lisa R Yanek Lihua Wang Edith Hofer Cornelius A Rietveld Olga McLeod Marilyn C Cornelis Cristian Pattaro Niek Verweij Clemens Baumbach Abdel Abdellaoui Helen R Warren Dragana Vuckovic Hao Mei Claude Bouchard John R B Perry Stefania Cappellani Saira S Mirza Miles C Benton Ulrich Broeckel Sarah E Medland Penelope A Lind Giovanni Malerba Alexander Drong Loic Yengo Lawrence F Bielak Degui Zhi Peter J van der Most Daniel Shriner Reedik Mägi Gibran Hemani Tugce Karaderi Zhaoming Wang Tian Liu Ilja Demuth Jing Hua Zhao Weihua Meng Lazaros Lataniotis Sander W van der Laan Jonathan P Bradfield Andrew R Wood Amelie Bonnefond Tarunveer S Ahluwalia Leanne M Hall Erika Salvi Seyhan Yazar Lisbeth Carstensen Hugoline G de Haan Mark Abney Uzma Afzal Matthew A Allison Najaf Amin Folkert W Asselbergs Stephan J L Bakker R Graham Barr Sebastian E Baumeister Daniel J Benjamin Sven Bergmann Eric Boerwinkle Erwin P Bottinger Archie Campbell Aravinda Chakravarti Yingleong Chan Stephen J Chanock Constance Chen Y-D Ida Chen Francis S Collins John Connell Adolfo Correa L Adrienne Cupples George Davey Smith Gail Davies Marcus Dörr Georg Ehret Stephen B Ellis Bjarke Feenstra Mary F Feitosa Ian Ford Caroline S Fox Timothy M Frayling Nele Friedrich Frank Geller Generation Scotland Irina Gillham-Nasenya Omri Gottesman Misa Graff Francine Grodstein Charles Gu Chris Haley Christopher J Hammond Sarah E Harris Tamara B Harris Nicholas D Hastie Nancy L Heard-Costa Kauko Heikkilä Lynne J Hocking Georg Homuth Jouke-Jan Hottenga Jinyan Huang Jennifer E Huffman Pirro G Hysi M Arfan Ikram Erik Ingelsson Anni Joensuu Åsa Johansson Pekka Jousilahti J Wouter Jukema Mika Kähönen Yoichiro Kamatani Stavroula Kanoni Shona M Kerr Nazir M Khan Philipp Koellinger Heikki A Koistinen Manraj K Kooner Michiaki Kubo Johanna Kuusisto Jari Lahti Lenore J Launer Rodney A Lea Benjamin Lehne Terho Lehtimäki David C M Liewald Lars Lind Marie Loh Marja-Liisa Lokki Stephanie J London Stephanie J Loomis Anu Loukola Yingchang Lu Thomas Lumley Annamari Lundqvist Satu Männistö Pedro Marques-Vidal Corrado Masciullo Angela Matchan Rasika A Mathias Koichi Matsuda James B Meigs Christa Meisinger Thomas Meitinger Cristina Menni Frank D Mentch Evelin Mihailov Lili Milani May E Montasser Grant W Montgomery Alanna Morrison Richard H Myers Rajiv Nadukuru Pau Navarro Mari Nelis Markku S Nieminen Ilja M Nolte George T O'Connor Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas James S Pankow Inga Patarcic Francesca Pavani Patricia A Peyser Kirsi Pietilainen Neil Poulter Inga Prokopenko Sarju Ralhan Paul Redmond Stephen S Rich Harri Rissanen Antonietta Robino Lynda M Rose Richard Rose Cinzia Sala Babatunde Salako Veikko Salomaa Antti-Pekka Sarin Richa Saxena Helena Schmidt Laura J Scott William R Scott Bengt Sennblad Sudha Seshadri Peter Sever Smeeta Shrestha Blair H Smith Jennifer A Smith Nicole Soranzo Nona Sotoodehnia Lorraine Southam Alice V Stanton Maria G Stathopoulou Konstantin Strauch Rona J Strawbridge Matthew J Suderman Nikhil Tandon Sian-Tsun Tang Kent D Taylor Bamidele O Tayo Anna Maria Töglhofer Maciej Tomaszewski Natalia Tšernikova Jaakko Tuomilehto Andre G Uitterlinden Dhananjay Vaidya Astrid van Hylckama Vlieg Jessica van Setten Tuula Vasankari Sailaja Vedantam Efthymia Vlachopoulou Diego Vozzi Eero Vuoksimaa Melanie Waldenberger Erin B Ware William Wentworth-Shields John B Whitfield Sarah Wild Gonneke Willemsen Chittaranjan S Yajnik Jie Yao Gianluigi Zaza Xiaofeng Zhu The BioBank Japan Project Rany M Salem Mads Melbye Hans Bisgaard Nilesh J Samani Daniele Cusi David A Mackey Richard S Cooper Philippe Froguel Gerard Pasterkamp Struan F A Grant Hakon Hakonarson Luigi Ferrucci Robert A Scott Andrew D Morris Colin N A Palmer George Dedoussis Panos Deloukas Lars Bertram Ulman Lindenberger Sonja I Berndt Cecilia M Lindgren Nicholas J Timpson Anke Tönjes Patricia B Munroe Thorkild I A Sørensen Charles N Rotimi Donna K Arnett Albertine J Oldehinkel Sharon L R Kardia Beverley Balkau Giovanni Gambaro Andrew P Morris Johan G Eriksson Margie J Wright Nicholas G Martin Steven C Hunt John M Starr Ian J Deary Lyn R Griffiths Henning Tiemeier Nicola Pirastu Jaakko Kaprio Nicholas J Wareham Louis Pérusse James G Wilson Giorgia Girotto Mark J Caulfield Olli Raitakari Dorret I Boomsma Christian Gieger Pim van der Harst Andrew A Hicks Peter Kraft Juha Sinisalo Paul Knekt Magnus Johannesson Patrik K E Magnusson Anders Hamsten Reinhold Schmidt Ingrid B Borecki Erkki Vartiainen Diane M Becker Dwaipayan Bharadwaj Karen L Mohlke Michael Boehnke Cornelia M van Duijn Dharambir K Sanghera Alexander Teumer Eleftheria Zeggini Andres Metspalu Paolo Gasparini Sheila Ulivi Carole Ober Daniela Toniolo Igor Rudan David J Porteous Marina Ciullo Tim D Spector Caroline Hayward Josée Dupuis Ruth J F Loos Alan F Wright Giriraj R Chandak Peter Vollenweider Alan Shuldiner Paul M Ridker Jerome I Rotter Naveed Sattar Ulf Gyllensten Kari E North Mario Pirastu Bruce M Psaty David R Weir Markku Laakso Vilmundur Gudnason Atsushi Takahashi John C Chambers Jaspal S Kooner David P Strachan Harry Campbell Joel N Hirschhorn Markus Perola Ozren Polašek James F Wilson

Nature 2015 Jul 1;523(7561):459-462. Epub 2015 Jul 1.

Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.

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http://dx.doi.org/10.1038/nature14618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516141PMC
July 2015

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.

Diabetes 2015 May 23;64(5):1841-52. Epub 2015 Feb 23.

Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.

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http://diabetes.diabetesjournals.org/content/64/5/1841.full.
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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db14
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http://dx.doi.org/10.2337/db14-0988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407863PMC
May 2015

Measuring short-term liver metabolism non-invasively: postprandial and post-exercise ¹H and ³¹P MR spectroscopy.

MAGMA 2015 Feb 4;28(1):57-66. Epub 2014 Jun 4.

Department of Radiology, HUS Medical Imaging Center, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland,

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http://dx.doi.org/10.1007/s10334-014-0450-7DOI Listing
February 2015

Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.

PLoS Med 2014 Dec 9;11(12):e1001765. Epub 2014 Dec 9.

Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Oulu University Hospital, Oulu, Finland; Computational Medicine, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260795PMC
December 2014

Persistence or change in leisure-time physical activity habits and waist gain during early adulthood: a twin-study.

Obesity (Silver Spring) 2014 Sep 16;22(9):2061-70. Epub 2014 May 16.

Department of Health Sciences, University of Jyväskylä, Finland.

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http://dx.doi.org/10.1002/oby.20788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149596PMC
September 2014

Genome-wide association analysis identifies six new loci associated with forced vital capacity.

Authors:
Daan W Loth María Soler Artigas Sina A Gharib Louise V Wain Nora Franceschini Beate Koch Tess D Pottinger Albert Vernon Smith Qing Duan Chris Oldmeadow Mi Kyeong Lee David P Strachan Alan L James Jennifer E Huffman Veronique Vitart Adaikalavan Ramasamy Nicholas J Wareham Jaakko Kaprio Xin-Qun Wang Holly Trochet Mika Kähönen Claudia Flexeder Eva Albrecht Lorna M Lopez Kim de Jong Bharat Thyagarajan Alexessander Couto Alves Stefan Enroth Ernst Omenaas Peter K Joshi Tove Fall Ana Viñuela Lenore J Launer Laura R Loehr Myriam Fornage Guo Li Jemma B Wilk Wenbo Tang Ani Manichaikul Lies Lahousse Tamara B Harris Kari E North Alicja R Rudnicka Jennie Hui Xiangjun Gu Thomas Lumley Alan F Wright Nicholas D Hastie Susan Campbell Rajesh Kumar Isabelle Pin Robert A Scott Kirsi H Pietiläinen Ida Surakka Yongmei Liu Elizabeth G Holliday Holger Schulz Joachim Heinrich Gail Davies Judith M Vonk Mary Wojczynski Anneli Pouta Asa Johansson Sarah H Wild Erik Ingelsson Fernando Rivadeneira Henry Völzke Pirro G Hysi Gudny Eiriksdottir Alanna C Morrison Jerome I Rotter Wei Gao Dirkje S Postma Wendy B White Stephen S Rich Albert Hofman Thor Aspelund David Couper Lewis J Smith Bruce M Psaty Kurt Lohman Esteban G Burchard André G Uitterlinden Melissa Garcia Bonnie R Joubert Wendy L McArdle A Bill Musk Nadia Hansel Susan R Heckbert Lina Zgaga Joyce B J van Meurs Pau Navarro Igor Rudan Yeon-Mok Oh Susan Redline Deborah L Jarvis Jing Hua Zhao Taina Rantanen George T O'Connor Samuli Ripatti Rodney J Scott Stefan Karrasch Harald Grallert Nathan C Gaddis John M Starr Cisca Wijmenga Ryan L Minster David J Lederer Juha Pekkanen Ulf Gyllensten Harry Campbell Andrew P Morris Sven Gläser Christopher J Hammond Kristin M Burkart John Beilby Stephen B Kritchevsky Vilmundur Gudnason Dana B Hancock O Dale Williams Ozren Polasek Tatijana Zemunik Ivana Kolcic Marcy F Petrini Matthias Wjst Woo Jin Kim David J Porteous Generation Scotland Blair H Smith Anne Viljanen Markku Heliövaara John R Attia Ian Sayers Regina Hampel Christian Gieger Ian J Deary H Marike Boezen Anne Newman Marjo-Riitta Jarvelin James F Wilson Lars Lind Bruno H Stricker Alexander Teumer Timothy D Spector Erik Melén Marjolein J Peters Leslie A Lange R Graham Barr Ken R Bracke Fien M Verhamme Joohon Sung Pieter S Hiemstra Patricia A Cassano Akshay Sood Caroline Hayward Josée Dupuis Ian P Hall Guy G Brusselle Martin D Tobin Stephanie J London

Nat Genet 2014 Jul 15;46(7):669-77. Epub 2014 Jun 15.

1] Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, North Carolina, USA. [2].

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http://dx.doi.org/10.1038/ng.3011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140093PMC
July 2014

Suppressed bone turnover in obesity: a link to energy metabolism? A case-control study.

J Clin Endocrinol Metab 2014 Jun 27;99(6):2155-63. Epub 2014 Feb 27.

Children's Hospital (H.V., P.P., M.L.-N., T.S., S.A., O.M.), Helsinki University Central Hospital, Obesity Research Unit (K.H.P.), Research Programs Unit, Diabetes and Obesity, University of Helsinki, and Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital and Institute for Molecular Medicine Finland, University of Helsinki, and Department of Obstetrics and Gynecology (K.L.), Helsinki University Central Hospital, FI-00029 Helsinki, Finland; Institute of Biomedicine (K.K.I.), Department of Cell Biology and Anatomy, University of Turku, FI-20520 Turku, Finland; Novartis Pharma (P.P.), CH-4002 Basel, Switzerland; Novo Nordisk Farma Oy (T.S.), FI-02240 Espoo, Finland; Folkhälsan Research Center (O.M.), FI-00250 Helsinki, Finland; and Department of Molecular Medicine and Surgery (O.M.), Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2013-3097DOI Listing
June 2014

Globular adiponectin and its downstream target genes are up-regulated locally in human colorectal tumors: ex vivo and in vitro studies.

Metabolism 2014 May 10;63(5):672-81. Epub 2014 Feb 10.

Department of Clinical Molecular Biology and Laboratory Sciences (EpiGen), Institute for Clinical Medicine, University of Oslo, Norway; Surgical Department, Akershus University Hospital, Lørenskog, Norway; Institute of Health Promotion, Akershus University Hospital, Lørenskog, Norway.

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http://dx.doi.org/10.1016/j.metabol.2014.02.001DOI Listing
May 2014

Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans.

Obesity (Silver Spring) 2013 Nov 13;21(11):2279-87. Epub 2013 Jun 13.

Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.

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http://dx.doi.org/10.1002/oby.20456DOI Listing
November 2013

Agreement of bioelectrical impedance with dual-energy X-ray absorptiometry and MRI to estimate changes in body fat, skeletal muscle and visceral fat during a 12-month weight loss intervention.

Br J Nutr 2013 May 31;109(10):1910-6. Epub 2012 Aug 31.

Obesity Research Unit, Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital, University of Helsinki, Biomedicum 1, Haartmaninkatu 8, PO Box 700, FIN-00029 HUCH, Finland.

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http://dx.doi.org/10.1017/S0007114512003698DOI Listing
May 2013

Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts.

PLoS One 2012 29;7(3):e31369. Epub 2012 Mar 29.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031369PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315559PMC
August 2012

Genetic influences on physical activity in young adults: a twin study.

Med Sci Sports Exerc 2012 Jul;44(7):1293-301

Hjelt Institute, Twin Research Unit, University of Helsinki, Helsinki, Finland.

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July 2012

Epicardial fat, cardiac dimensions, and low-grade inflammation in young adult monozygotic twins discordant for obesity.

Am J Cardiol 2012 May 10;109(9):1295-302. Epub 2012 Feb 10.

Department of Medicine, Division of Cardiology, Helsinki University Central Hospital, Finland.

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May 2012

Genetic and environmental factors influencing BMI development from adolescence to young adulthood.

Behav Genet 2012 Jan 17;42(1):73-85. Epub 2011 Aug 17.

Department of Public Health, University of Helsinki, Helsinki, Finland.

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January 2012

Obesity-related derangements of coagulation and fibrinolysis: a study of obesity-discordant monozygotic twin pairs.

Obesity (Silver Spring) 2012 Jan 29;20(1):88-94. Epub 2011 Sep 29.

Obesity Research Unit, Department of Medicine, Division of Internal Medicine and Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1038/oby.2011.287DOI Listing
January 2012

Circulating anti-Mullerian hormone levels in adult men are under a strong genetic influence.

J Clin Endocrinol Metab 2012 Jan 2;97(1):E161-4. Epub 2011 Nov 2.

Obesity Research Unit, Helsinki University Central Hospital, FI-00029 Helsinki, Finland.

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January 2012

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

Authors:
John C Chambers Weihua Zhang Joban Sehmi Xinzhong Li Mark N Wass Pim Van der Harst Hilma Holm Serena Sanna Maryam Kavousi Sebastian E Baumeister Lachlan J Coin Guohong Deng Christian Gieger Nancy L Heard-Costa Jouke-Jan Hottenga Brigitte Kühnel Vinod Kumar Vasiliki Lagou Liming Liang Jian'an Luan Pedro Marques Vidal Irene Mateo Leach Paul F O'Reilly John F Peden Nilufer Rahmioglu Pasi Soininen Elizabeth K Speliotes Xin Yuan Gudmar Thorleifsson Behrooz Z Alizadeh Larry D Atwood Ingrid B Borecki Morris J Brown Pimphen Charoen Francesco Cucca Debashish Das Eco J C de Geus Anna L Dixon Angela Döring Georg Ehret Gudmundur I Eyjolfsson Martin Farrall Nita G Forouhi Nele Friedrich Wolfram Goessling Daniel F Gudbjartsson Tamara B Harris Anna-Liisa Hartikainen Simon Heath Gideon M Hirschfield Albert Hofman Georg Homuth Elina Hyppönen Harry L A Janssen Toby Johnson Antti J Kangas Ido P Kema Jens P Kühn Sandra Lai Mark Lathrop Markus M Lerch Yun Li T Jake Liang Jing-Ping Lin Ruth J F Loos Nicholas G Martin Miriam F Moffatt Grant W Montgomery Patricia B Munroe Kiran Musunuru Yusuke Nakamura Christopher J O'Donnell Isleifur Olafsson Brenda W Penninx Anneli Pouta Bram P Prins Inga Prokopenko Ralf Puls Aimo Ruokonen Markku J Savolainen David Schlessinger Jeoffrey N L Schouten Udo Seedorf Srijita Sen-Chowdhry Katherine A Siminovitch Johannes H Smit Timothy D Spector Wenting Tan Tanya M Teslovich Taru Tukiainen Andre G Uitterlinden Melanie M Van der Klauw Ramachandran S Vasan Chris Wallace Henri Wallaschofski H-Erich Wichmann Gonneke Willemsen Peter Würtz Chun Xu Laura M Yerges-Armstrong Goncalo R Abecasis Kourosh R Ahmadi Dorret I Boomsma Mark Caulfield William O Cookson Cornelia M van Duijn Philippe Froguel Koichi Matsuda Mark I McCarthy Christa Meisinger Vincent Mooser Kirsi H Pietiläinen Gunter Schumann Harold Snieder Michael J E Sternberg Ronald P Stolk Howard C Thomas Unnur Thorsteinsdottir Manuela Uda Gérard Waeber Nicholas J Wareham Dawn M Waterworth Hugh Watkins John B Whitfield Jacqueline C M Witteman Bruce H R Wolffenbuttel Caroline S Fox Mika Ala-Korpela Kari Stefansson Peter Vollenweider Henry Völzke Eric E Schadt James Scott Marjo-Riitta Järvelin Paul Elliott Jaspal S Kooner

Nat Genet 2011 Oct 16;43(11):1131-8. Epub 2011 Oct 16.

Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482372PMC
October 2011

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Authors:
María Soler Artigas Daan W Loth Louise V Wain Sina A Gharib Ma'en Obeidat Wenbo Tang Guangju Zhai Jing Hua Zhao Albert Vernon Smith Jennifer E Huffman Eva Albrecht Catherine M Jackson David M Evans Gemma Cadby Myriam Fornage Ani Manichaikul Lorna M Lopez Toby Johnson Melinda C Aldrich Thor Aspelund Inês Barroso Harry Campbell Patricia A Cassano David J Couper Gudny Eiriksdottir Nora Franceschini Melissa Garcia Christian Gieger Gauti Kjartan Gislason Ivica Grkovic Christopher J Hammond Dana B Hancock Tamara B Harris Adaikalavan Ramasamy Susan R Heckbert Markku Heliövaara Georg Homuth Pirro G Hysi Alan L James Stipan Jankovic Bonnie R Joubert Stefan Karrasch Norman Klopp Beate Koch Stephen B Kritchevsky Lenore J Launer Yongmei Liu Laura R Loehr Kurt Lohman Ruth J F Loos Thomas Lumley Khalid A Al Balushi Wei Q Ang R Graham Barr John Beilby John D Blakey Mladen Boban Vesna Boraska Jonas Brisman John R Britton Guy G Brusselle Cyrus Cooper Ivan Curjuric Santosh Dahgam Ian J Deary Shah Ebrahim Mark Eijgelsheim Clyde Francks Darya Gaysina Raquel Granell Xiangjun Gu John L Hankinson Rebecca Hardy Sarah E Harris John Henderson Amanda Henry Aroon D Hingorani Albert Hofman Patrick G Holt Jennie Hui Michael L Hunter Medea Imboden Karen A Jameson Shona M Kerr Ivana Kolcic Florian Kronenberg Jason Z Liu Jonathan Marchini Tricia McKeever Andrew D Morris Anna-Carin Olin David J Porteous Dirkje S Postma Stephen S Rich Susan M Ring Fernando Rivadeneira Thierry Rochat Avan Aihie Sayer Ian Sayers Peter D Sly George Davey Smith Akshay Sood John M Starr André G Uitterlinden Judith M Vonk S Goya Wannamethee Peter H Whincup Cisca Wijmenga O Dale Williams Andrew Wong Massimo Mangino Kristin D Marciante Wendy L McArdle Bernd Meibohm Alanna C Morrison Kari E North Ernst Omenaas Lyle J Palmer Kirsi H Pietiläinen Isabelle Pin Ozren Pola Sbreve Ek Anneli Pouta Bruce M Psaty Anna-Liisa Hartikainen Taina Rantanen Samuli Ripatti Jerome I Rotter Igor Rudan Alicja R Rudnicka Holger Schulz So-Youn Shin Tim D Spector Ida Surakka Veronique Vitart Henry Völzke Nicholas J Wareham Nicole M Warrington H-Erich Wichmann Sarah H Wild Jemma B Wilk Matthias Wjst Alan F Wright Lina Zgaga Tatijana Zemunik Craig E Pennell Fredrik Nyberg Diana Kuh John W Holloway H Marike Boezen Debbie A Lawlor Richard W Morris Nicole Probst-Hensch Jaakko Kaprio James F Wilson Caroline Hayward Mika Kähönen Joachim Heinrich Arthur W Musk Deborah L Jarvis Sven Gläser Marjo-Riitta Järvelin Bruno H Ch Stricker Paul Elliott George T O'Connor David P Strachan Stephanie J London Ian P Hall Vilmundur Gudnason Martin D Tobin

Nat Genet 2011 Sep 25;43(11):1082-90. Epub 2011 Sep 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267376PMC
September 2011

Leisure-time physical activity and nutrition: a twin study.

Public Health Nutr 2011 May 4;14(5):846-52. Epub 2010 May 4.

Department of Health Sciences, University of Jyväskylä, PO Box 35(LL), FIN-40014, Finland.

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May 2011

Liver fat but not other adiposity measures influence circulating FGF21 levels in healthy young adult twins.

J Clin Endocrinol Metab 2011 Feb 1;96(2):E351-5. Epub 2010 Dec 1.

Research Program of Molecular Neurology, Biomedicum Helsinki, r.C523B, Haartmaninkatu 8, 00290 Helsinki, Finland.

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February 2011

Increased coagulation factor VIII, IX, XI and XII activities in non-alcoholic fatty liver disease.

Liver Int 2011 Feb 7;31(2):176-83. Epub 2010 Dec 7.

Department of Medicine, Division of Diabetes, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1111/j.1478-3231.2010.02375.xDOI Listing
February 2011

Comparison of the relative contributions of intra-abdominal and liver fat to components of the metabolic syndrome.

Obesity (Silver Spring) 2011 Jan 10;19(1):23-8. Epub 2010 Jun 10.

Department of Medicine, Division of Diabetes, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/oby.2010.137DOI Listing
January 2011

An investigation into the relationship between soft tissue body composition and bone mineral density in a young adult twin sample.

J Bone Miner Res 2011 Jan;26(1):79-87

The Finnish Twin Cohort Study, Department of Public Health, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/jbmr.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179317PMC
January 2011

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Authors:
Iris M Heid Anne U Jackson Joshua C Randall Thomas W Winkler Lu Qi Valgerdur Steinthorsdottir Gudmar Thorleifsson M Carola Zillikens Elizabeth K Speliotes Reedik Mägi Tsegaselassie Workalemahu Charles C White Nabila Bouatia-Naji Tamara B Harris Sonja I Berndt Erik Ingelsson Cristen J Willer Michael N Weedon Jian'an Luan Sailaja Vedantam Tõnu Esko Tuomas O Kilpeläinen Zoltán Kutalik Shengxu Li Keri L Monda Anna L Dixon Christopher C Holmes Lee M Kaplan Liming Liang Josine L Min Miriam F Moffatt Cliona Molony George Nicholson Eric E Schadt Krina T Zondervan Mary F Feitosa Teresa Ferreira Hana Lango Allen Robert J Weyant Eleanor Wheeler Andrew R Wood Karol Estrada Michael E Goddard Guillaume Lettre Massimo Mangino Dale R Nyholt Shaun Purcell Albert Vernon Smith Peter M Visscher Jian Yang Steven A McCarroll James Nemesh Benjamin F Voight Devin Absher Najaf Amin Thor Aspelund Lachlan Coin Nicole L Glazer Caroline Hayward Nancy L Heard-Costa Jouke-Jan Hottenga Asa Johansson Toby Johnson Marika Kaakinen Karen Kapur Shamika Ketkar Joshua W Knowles Peter Kraft Aldi T Kraja Claudia Lamina Michael F Leitzmann Barbara McKnight Andrew P Morris Ken K Ong John R B Perry Marjolein J Peters Ozren Polasek Inga Prokopenko Nigel W Rayner Samuli Ripatti Fernando Rivadeneira Neil R Robertson Serena Sanna Ulla Sovio Ida Surakka Alexander Teumer Sophie van Wingerden Veronique Vitart Jing Hua Zhao Christine Cavalcanti-Proença Peter S Chines Eva Fisher Jennifer R Kulzer Cecile Lecoeur Narisu Narisu Camilla Sandholt Laura J Scott Kaisa Silander Klaus Stark Mari-Liis Tammesoo Tanya M Teslovich Nicholas John Timpson Richard M Watanabe Ryan Welch Daniel I Chasman Matthew N Cooper John-Olov Jansson Johannes Kettunen Robert W Lawrence Niina Pellikka Markus Perola Liesbeth Vandenput Helene Alavere Peter Almgren Larry D Atwood Amanda J Bennett Reiner Biffar Lori L Bonnycastle Stefan R Bornstein Thomas A Buchanan Harry Campbell Ian N M Day Mariano Dei Marcus Dörr Paul Elliott Michael R Erdos Johan G Eriksson Nelson B Freimer Mao Fu Stefan Gaget Eco J C Geus Anette P Gjesing Harald Grallert Jürgen Grässler Christopher J Groves Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Aki S Havulinna Karl-Heinz Herzig Andrew A Hicks Jennie Hui Wilmar Igl Pekka Jousilahti Antti Jula Eero Kajantie Leena Kinnunen Ivana Kolcic Seppo Koskinen Peter Kovacs Heyo K Kroemer Vjekoslav Krzelj Johanna Kuusisto Kirsti Kvaloy Jaana Laitinen Olivier Lantieri G Mark Lathrop Marja-Liisa Lokki Robert N Luben Barbara Ludwig Wendy L McArdle Anne McCarthy Mario A Morken Mari Nelis Matt J Neville Guillaume Paré Alex N Parker John F Peden Irene Pichler Kirsi H Pietiläinen Carl G P Platou Anneli Pouta Martin Ridderstråle Nilesh J Samani Jouko Saramies Juha Sinisalo Jan H Smit Rona J Strawbridge Heather M Stringham Amy J Swift Maris Teder-Laving Brian Thomson Gianluca Usala Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Claudia B Volpato Henri Wallaschofski G Bragi Walters Elisabeth Widen Sarah H Wild Gonneke Willemsen Daniel R Witte Lina Zgaga Paavo Zitting John P Beilby Alan L James Mika Kähönen Terho Lehtimäki Markku S Nieminen Claes Ohlsson Lyle J Palmer Olli Raitakari Paul M Ridker Michael Stumvoll Anke Tönjes Jorma Viikari Beverley Balkau Yoav Ben-Shlomo Richard N Bergman Heiner Boeing George Davey Smith Shah Ebrahim Philippe Froguel Torben Hansen Christian Hengstenberg Kristian Hveem Bo Isomaa Torben Jørgensen Fredrik Karpe Kay-Tee Khaw Markku Laakso Debbie A Lawlor Michel Marre Thomas Meitinger Andres Metspalu Kristian Midthjell Oluf Pedersen Veikko Salomaa Peter E H Schwarz Tiinamaija Tuomi Jaakko Tuomilehto Timo T Valle Nicholas J Wareham Alice M Arnold Jacques S Beckmann Sven Bergmann Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Francis S Collins Gudny Eiriksdottir Vilmundur Gudnason Ulf Gyllensten Anders Hamsten Andrew T Hattersley Albert Hofman Frank B Hu Thomas Illig Carlos Iribarren Marjo-Riitta Jarvelin W H Linda Kao Jaakko Kaprio Lenore J Launer Patricia B Munroe Ben Oostra Brenda W Penninx Peter P Pramstaller Bruce M Psaty Thomas Quertermous Aila Rissanen Igor Rudan Alan R Shuldiner Nicole Soranzo Timothy D Spector Ann-Christine Syvanen Manuela Uda André Uitterlinden Henry Völzke Peter Vollenweider James F Wilson Jacqueline C Witteman Alan F Wright Gonçalo R Abecasis Michael Boehnke Ingrid B Borecki Panos Deloukas Timothy M Frayling Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Kari E North Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Joel N Hirschhorn Themistocles L Assimes H-Erich Wichmann Unnur Thorsteinsdottir Cornelia M van Duijn Kari Stefansson L Adrienne Cupples Ruth J F Loos Inês Barroso Mark I McCarthy Caroline S Fox Karen L Mohlke Cecilia M Lindgren

Nat Genet 2010 Nov 10;42(11):949-60. Epub 2010 Oct 10.

Regensburg University Medical Center, Department of Epidemiology and Preventive Medicine, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000924PMC
November 2010

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Authors:
Elizabeth K Speliotes Cristen J Willer Sonja I Berndt Keri L Monda Gudmar Thorleifsson Anne U Jackson Hana Lango Allen Cecilia M Lindgren Jian'an Luan Reedik Mägi Joshua C Randall Sailaja Vedantam Thomas W Winkler Lu Qi Tsegaselassie Workalemahu Iris M Heid Valgerdur Steinthorsdottir Heather M Stringham Michael N Weedon Eleanor Wheeler Andrew R Wood Teresa Ferreira Robert J Weyant Ayellet V Segrè Karol Estrada Liming Liang James Nemesh Ju-Hyun Park Stefan Gustafsson Tuomas O Kilpeläinen Jian Yang Nabila Bouatia-Naji Tõnu Esko Mary F Feitosa Zoltán Kutalik Massimo Mangino Soumya Raychaudhuri Andre Scherag Albert Vernon Smith Ryan Welch Jing Hua Zhao Katja K Aben Devin M Absher Najaf Amin Anna L Dixon Eva Fisher Nicole L Glazer Michael E Goddard Nancy L Heard-Costa Volker Hoesel Jouke-Jan Hottenga Asa Johansson Toby Johnson Shamika Ketkar Claudia Lamina Shengxu Li Miriam F Moffatt Richard H Myers Narisu Narisu John R B Perry Marjolein J Peters Michael Preuss Samuli Ripatti Fernando Rivadeneira Camilla Sandholt Laura J Scott Nicholas J Timpson Jonathan P Tyrer Sophie van Wingerden Richard M Watanabe Charles C White Fredrik Wiklund Christina Barlassina Daniel I Chasman Matthew N Cooper John-Olov Jansson Robert W Lawrence Niina Pellikka Inga Prokopenko Jianxin Shi Elisabeth Thiering Helene Alavere Maria T S Alibrandi Peter Almgren Alice M Arnold Thor Aspelund Larry D Atwood Beverley Balkau Anthony J Balmforth Amanda J Bennett Yoav Ben-Shlomo Richard N Bergman Sven Bergmann Heike Biebermann Alexandra I F Blakemore Tanja Boes Lori L Bonnycastle Stefan R Bornstein Morris J Brown Thomas A Buchanan Fabio Busonero Harry Campbell Francesco P Cappuccio Christine Cavalcanti-Proença Yii-Der Ida Chen Chih-Mei Chen Peter S Chines Robert Clarke Lachlan Coin John Connell Ian N M Day Martin den Heijer Jubao Duan Shah Ebrahim Paul Elliott Roberto Elosua Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Maurizio F Facheris Stephan B Felix Pamela Fischer-Posovszky Aaron R Folsom Nele Friedrich Nelson B Freimer Mao Fu Stefan Gaget Pablo V Gejman Eco J C Geus Christian Gieger Anette P Gjesing Anuj Goel Philippe Goyette Harald Grallert Jürgen Grässler Danielle M Greenawalt Christopher J Groves Vilmundur Gudnason Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Alistair S Hall Aki S Havulinna Caroline Hayward Andrew C Heath Christian Hengstenberg Andrew A Hicks Anke Hinney Albert Hofman Georg Homuth Jennie Hui Wilmar Igl Carlos Iribarren Bo Isomaa Kevin B Jacobs Ivonne Jarick Elizabeth Jewell Ulrich John Torben Jørgensen Pekka Jousilahti Antti Jula Marika Kaakinen Eero Kajantie Lee M Kaplan Sekar Kathiresan Johannes Kettunen Leena Kinnunen Joshua W Knowles Ivana Kolcic Inke R König Seppo Koskinen Peter Kovacs Johanna Kuusisto Peter Kraft Kirsti Kvaløy Jaana Laitinen Olivier Lantieri Chiara Lanzani Lenore J Launer Cecile Lecoeur Terho Lehtimäki Guillaume Lettre Jianjun Liu Marja-Liisa Lokki Mattias Lorentzon Robert N Luben Barbara Ludwig Paolo Manunta Diana Marek Michel Marre Nicholas G Martin Wendy L McArdle Anne McCarthy Barbara McKnight Thomas Meitinger Olle Melander David Meyre Kristian Midthjell Grant W Montgomery Mario A Morken Andrew P Morris Rosanda Mulic Julius S Ngwa Mari Nelis Matt J Neville Dale R Nyholt Christopher J O'Donnell Stephen O'Rahilly Ken K Ong Ben Oostra Guillaume Paré Alex N Parker Markus Perola Irene Pichler Kirsi H Pietiläinen Carl G P Platou Ozren Polasek Anneli Pouta Suzanne Rafelt Olli Raitakari Nigel W Rayner Martin Ridderstråle Winfried Rief Aimo Ruokonen Neil R Robertson Peter Rzehak Veikko Salomaa Alan R Sanders Manjinder S Sandhu Serena Sanna Jouko Saramies Markku J Savolainen Susann Scherag Sabine Schipf Stefan Schreiber Heribert Schunkert Kaisa Silander Juha Sinisalo David S Siscovick Jan H Smit Nicole Soranzo Ulla Sovio Jonathan Stephens Ida Surakka Amy J Swift Mari-Liis Tammesoo Jean-Claude Tardif Maris Teder-Laving Tanya M Teslovich John R Thompson Brian Thomson Anke Tönjes Tiinamaija Tuomi Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Jorma Viikari Sophie Visvikis-Siest Veronique Vitart Carla I G Vogel Benjamin F Voight Lindsay L Waite Henri Wallaschofski G Bragi Walters Elisabeth Widen Susanna Wiegand Sarah H Wild Gonneke Willemsen Daniel R Witte Jacqueline C Witteman Jianfeng Xu Qunyuan Zhang Lina Zgaga Andreas Ziegler Paavo Zitting John P Beilby I Sadaf Farooqi Johannes Hebebrand Heikki V Huikuri Alan L James Mika Kähönen Douglas F Levinson Fabio Macciardi Markku S Nieminen Claes Ohlsson Lyle J Palmer Paul M Ridker Michael Stumvoll Jacques S Beckmann Heiner Boeing Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock Francis S Collins L Adrienne Cupples George Davey Smith Jeanette Erdmann Philippe Froguel Henrik Grönberg Ulf Gyllensten Per Hall Torben Hansen Tamara B Harris Andrew T Hattersley Richard B Hayes Joachim Heinrich Frank B Hu Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Jaakko Kaprio Fredrik Karpe Kay-Tee Khaw Lambertus A Kiemeney Heiko Krude Markku Laakso Debbie A Lawlor Andres Metspalu Patricia B Munroe Willem H Ouwehand Oluf Pedersen Brenda W Penninx Annette Peters Peter P Pramstaller Thomas Quertermous Thomas Reinehr Aila Rissanen Igor Rudan Nilesh J Samani Peter E H Schwarz Alan R Shuldiner Timothy D Spector Jaakko Tuomilehto Manuela Uda André Uitterlinden Timo T Valle Martin Wabitsch Gérard Waeber Nicholas J Wareham Hugh Watkins James F Wilson Alan F Wright M Carola Zillikens Nilanjan Chatterjee Steven A McCarroll Shaun Purcell Eric E Schadt Peter M Visscher Themistocles L Assimes Ingrid B Borecki Panos Deloukas Caroline S Fox Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Karen L Mohlke Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Cornelia M van Duijn H-Erich Wichmann Timothy M Frayling Unnur Thorsteinsdottir Gonçalo R Abecasis Inês Barroso Michael Boehnke Kari Stefansson Kari E North Mark I McCarthy Joel N Hirschhorn Erik Ingelsson Ruth J F Loos

Nat Genet 2010 Nov 10;42(11):937-48. Epub 2010 Oct 10.

Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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November 2010

Mitochondrial myopathy induces a starvation-like response.

Hum Mol Genet 2010 Oct 23;19(20):3948-58. Epub 2010 Jul 23.

Research Program of Molecular Neurology, Biomedicum-Helsinki, 00290 Helsinki, Finland.

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October 2010

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

Authors:
Hana Lango Allen Karol Estrada Guillaume Lettre Sonja I Berndt Michael N Weedon Fernando Rivadeneira Cristen J Willer Anne U Jackson Sailaja Vedantam Soumya Raychaudhuri Teresa Ferreira Andrew R Wood Robert J Weyant Ayellet V Segrè Elizabeth K Speliotes Eleanor Wheeler Nicole Soranzo Ju-Hyun Park Jian Yang Daniel Gudbjartsson Nancy L Heard-Costa Joshua C Randall Lu Qi Albert Vernon Smith Reedik Mägi Tomi Pastinen Liming Liang Iris M Heid Jian'an Luan Gudmar Thorleifsson Thomas W Winkler Michael E Goddard Ken Sin Lo Cameron Palmer Tsegaselassie Workalemahu Yurii S Aulchenko Asa Johansson M Carola Zillikens Mary F Feitosa Tõnu Esko Toby Johnson Shamika Ketkar Peter Kraft Massimo Mangino Inga Prokopenko Devin Absher Eva Albrecht Florian Ernst Nicole L Glazer Caroline Hayward Jouke-Jan Hottenga Kevin B Jacobs Joshua W Knowles Zoltán Kutalik Keri L Monda Ozren Polasek Michael Preuss Nigel W Rayner Neil R Robertson Valgerdur Steinthorsdottir Jonathan P Tyrer Benjamin F Voight Fredrik Wiklund Jianfeng Xu Jing Hua Zhao Dale R Nyholt Niina Pellikka Markus Perola John R B Perry Ida Surakka Mari-Liis Tammesoo Elizabeth L Altmaier Najaf Amin Thor Aspelund Tushar Bhangale Gabrielle Boucher Daniel I Chasman Constance Chen Lachlan Coin Matthew N Cooper Anna L Dixon Quince Gibson Elin Grundberg Ke Hao M Juhani Junttila Lee M Kaplan Johannes Kettunen Inke R König Tony Kwan Robert W Lawrence Douglas F Levinson Mattias Lorentzon Barbara McKnight Andrew P Morris Martina Müller Julius Suh Ngwa Shaun Purcell Suzanne Rafelt Rany M Salem Erika Salvi Serena Sanna Jianxin Shi Ulla Sovio John R Thompson Michael C Turchin Liesbeth Vandenput Dominique J Verlaan Veronique Vitart Charles C White Andreas Ziegler Peter Almgren Anthony J Balmforth Harry Campbell Lorena Citterio Alessandro De Grandi Anna Dominiczak Jubao Duan Paul Elliott Roberto Elosua Johan G Eriksson Nelson B Freimer Eco J C Geus Nicola Glorioso Shen Haiqing Anna-Liisa Hartikainen Aki S Havulinna Andrew A Hicks Jennie Hui Wilmar Igl Thomas Illig Antti Jula Eero Kajantie Tuomas O Kilpeläinen Markku Koiranen Ivana Kolcic Seppo Koskinen Peter Kovacs Jaana Laitinen Jianjun Liu Marja-Liisa Lokki Ana Marusic Andrea Maschio Thomas Meitinger Antonella Mulas Guillaume Paré Alex N Parker John F Peden Astrid Petersmann Irene Pichler Kirsi H Pietiläinen Anneli Pouta Martin Ridderstråle Jerome I Rotter Jennifer G Sambrook Alan R Sanders Carsten Oliver Schmidt Juha Sinisalo Jan H Smit Heather M Stringham G Bragi Walters Elisabeth Widen Sarah H Wild Gonneke Willemsen Laura Zagato Lina Zgaga Paavo Zitting Helene Alavere Martin Farrall Wendy L McArdle Mari Nelis Marjolein J Peters Samuli Ripatti Joyce B J van Meurs Katja K Aben Kristin G Ardlie Jacques S Beckmann John P Beilby Richard N Bergman Sven Bergmann Francis S Collins Daniele Cusi Martin den Heijer Gudny Eiriksdottir Pablo V Gejman Alistair S Hall Anders Hamsten Heikki V Huikuri Carlos Iribarren Mika Kähönen Jaakko Kaprio Sekar Kathiresan Lambertus Kiemeney Thomas Kocher Lenore J Launer Terho Lehtimäki Olle Melander Tom H Mosley Arthur W Musk Markku S Nieminen Christopher J O'Donnell Claes Ohlsson Ben Oostra Lyle J Palmer Olli Raitakari Paul M Ridker John D Rioux Aila Rissanen Carlo Rivolta Heribert Schunkert Alan R Shuldiner David S Siscovick Michael Stumvoll Anke Tönjes Jaakko Tuomilehto Gert-Jan van Ommen Jorma Viikari Andrew C Heath Nicholas G Martin Grant W Montgomery Michael A Province Manfred Kayser Alice M Arnold Larry D Atwood Eric Boerwinkle Stephen J Chanock Panos Deloukas Christian Gieger Henrik Grönberg Per Hall Andrew T Hattersley Christian Hengstenberg Wolfgang Hoffman G Mark Lathrop Veikko Salomaa Stefan Schreiber Manuela Uda Dawn Waterworth Alan F Wright Themistocles L Assimes Inês Barroso Albert Hofman Karen L Mohlke Dorret I Boomsma Mark J Caulfield L Adrienne Cupples Jeanette Erdmann Caroline S Fox Vilmundur Gudnason Ulf Gyllensten Tamara B Harris Richard B Hayes Marjo-Riitta Jarvelin Vincent Mooser Patricia B Munroe Willem H Ouwehand Brenda W Penninx Peter P Pramstaller Thomas Quertermous Igor Rudan Nilesh J Samani Timothy D Spector Henry Völzke Hugh Watkins James F Wilson Leif C Groop Talin Haritunians Frank B Hu Robert C Kaplan Andres Metspalu Kari E North David Schlessinger Nicholas J Wareham David J Hunter Jeffrey R O'Connell David P Strachan H-Erich Wichmann Ingrid B Borecki Cornelia M van Duijn Eric E Schadt Unnur Thorsteinsdottir Leena Peltonen André G Uitterlinden Peter M Visscher Nilanjan Chatterjee Ruth J F Loos Michael Boehnke Mark I McCarthy Erik Ingelsson Cecilia M Lindgren Gonçalo R Abecasis Kari Stefansson Timothy M Frayling Joel N Hirschhorn

Nature 2010 Oct 29;467(7317):832-8. Epub 2010 Sep 29.

Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter EX1 2LU, UK.

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http://dx.doi.org/10.1038/nature09410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955183PMC
October 2010

The effect of alcohol consumption on later obesity in early adulthood--a population-based longitudinal study.

Alcohol Alcohol 2010 Mar-Apr;45(2):173-9. Epub 2010 Jan 12.

Department of Public Health, University of Helsinki, PO Box 14, 00014 Helsinki, Finland.

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http://dx.doi.org/10.1093/alcalc/agp090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842105PMC
April 2010

Twin study of heritability of eating bread in Danish and Finnish men and women.

Twin Res Hum Genet 2010 Apr;13(2):163-7

Institute of Preventive Medicine, Copenhagen Capital Region, Copenhagen University Hospitals, Centre for Health and Society, DK-1357 Copenhagen, Denmark.

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http://dx.doi.org/10.1375/twin.13.2.163DOI Listing
April 2010

Improving the accuracy of self-reports on diet and physical exercise: the co-twin control method.

Twin Res Hum Genet 2009 Dec;12(6):531-40

The Finnish Twin Cohort Study, Department of Public Health, University of Helsinki, Finland.

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http://dx.doi.org/10.1375/twin.12.6.531DOI Listing
December 2009

Cardiac repolarization and striatal dopamine transporter function are interrelated.

Nucl Med Commun 2009 Sep;30(9):713-7

Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1097/MNM.0b013e32832bdc96DOI Listing
September 2009

HDL subspecies in young adult twins: heritability and impact of overweight.

Obesity (Silver Spring) 2009 Jun 19;17(6):1208-14. Epub 2009 Feb 19.

Obesity Research Unit, Department of Psychiatry, Helsinki University Central Hospital, Finnish Twin Cohort Study, Department of Public Health, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/oby.2008.675DOI Listing
June 2009

Association of smoking in adolescence with abdominal obesity in adulthood: a follow-up study of 5 birth cohorts of Finnish twins.

Am J Public Health 2009 Feb 4;99(2):348-54. Epub 2008 Dec 4.

Department of Public Health, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.2105/AJPH.2007.123851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2622791PMC
February 2009

Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity.

Am J Physiol Endocrinol Metab 2008 Jul 6;295(1):E148-54. Epub 2008 May 6.

Department of Laboratory Medicine, Division of Clinical Physiology and Nuclear Medicine, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1152/ajpendo.00580.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493587PMC
July 2008