Kirk E Lohmueller

Kirk E Lohmueller

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Kirk E Lohmueller

Kirk E Lohmueller

Publications by authors named "Kirk E Lohmueller"

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54Publications

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Ten simple rules for giving an effective academic job talk.

PLoS Comput Biol 2019 Jul 25;15(7):e1007163. Epub 2019 Jul 25.

Department of Ecology and Evolutionary Biology, University of California Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1007163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657819PMC
July 2019

Complex patterns of sex-biased demography in canines.

Proc Biol Sci 2019 May;286(1903):20181976

1 Interdepartmental Program in Bioinformatics, University of California , Los Angeles, CA 90095 , USA.

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http://dx.doi.org/10.1098/rspb.2018.1976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545087PMC
May 2019

Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction.

Sci Adv 2019 May 29;5(5):eaau0757. Epub 2019 May 29.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1126/sciadv.aau0757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541468PMC
May 2019

RADseq data reveal ancient, but not pervasive, introgression between Californian tree and scrub oak species (Quercus sect. Quercus: Fagaceae).

Mol Ecol 2018 11 12;27(22):4556-4571. Epub 2018 Oct 12.

Department of Ecology and Evolutionary Biology, University of California at Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1111/mec.14869DOI Listing
November 2018

Understanding the Hidden Complexity of Latin American Population Isolates.

Am J Hum Genet 2018 11 25;103(5):707-726. Epub 2018 Oct 25.

Department of Human Genetics, University of California Los Angeles, Los Angeles, CA 90095, USA; Department of Ecology & Evolutionary Biology, University of California Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183035
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http://dx.doi.org/10.1016/j.ajhg.2018.09.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218714PMC
November 2018

Purging of Strongly Deleterious Mutations Explains Long-Term Persistence and Absence of Inbreeding Depression in Island Foxes.

Curr Biol 2018 Nov 25;28(21):3487-3494.e4. Epub 2018 Oct 25.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09609822183119
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http://dx.doi.org/10.1016/j.cub.2018.08.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462144PMC
November 2018

Deleterious variation shapes the genomic landscape of introgression.

PLoS Genet 2018 10 22;14(10):e1007741. Epub 2018 Oct 22.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233928PMC
October 2018

Gene expression drives the evolution of dominance.

Nat Commun 2018 07 16;9(1):2750. Epub 2018 Jul 16.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1038/s41467-018-05281-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048131PMC
July 2018

Comparison of Single Genome and Allele Frequency Data Reveals Discordant Demographic Histories.

G3 (Bethesda) 2017 11 6;7(11):3605-3620. Epub 2017 Nov 6.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, California 90095

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http://dx.doi.org/10.1534/g3.117.300259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677151PMC
November 2017

Genomic divergence across ecological gradients in the Central African rainforest songbird (Andropadus virens).

Mol Ecol 2017 Oct 21;26(19):4966-4977. Epub 2017 Aug 21.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/mec.14270DOI Listing
October 2017

Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples.

Genetics 2017 05 1;206(1):345-361. Epub 2017 Mar 1.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, California 90095

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http://dx.doi.org/10.1534/genetics.116.197145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419480PMC
May 2017

Determining the factors driving selective effects of new nonsynonymous mutations.

Proc Natl Acad Sci U S A 2017 04 11;114(17):4465-4470. Epub 2017 Apr 11.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095;

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http://dx.doi.org/10.1073/pnas.1619508114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410820PMC
April 2017

PReFerSim: fast simulation of demography and selection under the Poisson Random Field model.

Bioinformatics 2016 11 19;32(22):3516-3518. Epub 2016 Jul 19.

Interdepartmental Program in Bioinformatics, University of California, Los Angeles, CA 90095, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btw478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181561PMC
November 2016

Determining the Effect of Natural Selection on Linked Neutral Divergence across Species.

PLoS Genet 2016 08 10;12(8):e1006199. Epub 2016 Aug 10.

Interdepartmental Program in Bioinformatics, University of California, Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980041PMC
August 2016

An assessment of the information content of likelihood ratios derived from complex mixtures.

Forensic Sci Int Genet 2016 May 19;22:64-72. Epub 2016 Jan 19.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, 621 Charles E. Young Dr. South, Los Angeles, CA 90095-1606, USA. Electronic address:

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http://dx.doi.org/10.1016/j.fsigen.2016.01.008DOI Listing
May 2016

Genomic Flatlining in the Endangered Island Fox.

Curr Biol 2016 05 21;26(9):1183-9. Epub 2016 Apr 21.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://www.cell.com/current-biology/pdf/S0960-9822(16)30173-
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http://dx.doi.org/10.1016/j.cub.2016.02.062DOI Listing
May 2016

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders.

Eur J Hum Genet 2016 Jan 22;24(1):113-9. Epub 2015 Apr 22.

Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/ejhg.2015.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795218PMC
January 2016

Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs.

Proc Natl Acad Sci U S A 2016 01 22;113(1):152-7. Epub 2015 Dec 22.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095; Interdepartmental Program in Bioinformatics, University of California, Los Angeles, CA 90095; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095

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http://dx.doi.org/10.1073/pnas.1512501113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711855PMC
January 2016

Fitting the Balding-Nichols model to forensic databases.

Forensic Sci Int Genet 2015 Nov 23;19:86-91. Epub 2015 Jun 23.

University of California, Berkeley, Department of Integrative Biology, United States.

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http://dx.doi.org/10.1016/j.fsigen.2015.05.005DOI Listing
November 2015

Lab Retriever: a software tool for calculating likelihood ratios incorporating a probability of drop-out for forensic DNA profiles.

BMC Bioinformatics 2015 Sep 18;16:298. Epub 2015 Sep 18.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, 621 Charles E. Young Dr. South, Los Angeles, CA, 90095-1606, USA.

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http://dx.doi.org/10.1186/s12859-015-0740-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575494PMC
September 2015

Selection and reduced population size cannot explain higher amounts of Neandertal ancestry in East Asian than in European human populations.

Am J Hum Genet 2015 Mar 12;96(3):454-61. Epub 2015 Feb 12.

Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Interdepartmental Program in Bioinformatics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297150000
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http://dx.doi.org/10.1016/j.ajhg.2014.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375557PMC
March 2015

The impact of population demography and selection on the genetic architecture of complex traits.

PLoS Genet 2014 29;10(5):e1004379. Epub 2014 May 29.

Department of Ecology and Evolutionary Biology, Interdepartmental Program in Bioinformatics, University of California, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038606PMC
December 2014

The distribution of deleterious genetic variation in human populations.

Curr Opin Genet Dev 2014 Dec;29:139-46

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http://dx.doi.org/10.1016/j.gde.2014.09.005DOI Listing
December 2014

Analysis of allelic drop-out using the Identifiler(®) and PowerPlex(®) 16 forensic STR typing systems.

Forensic Sci Int Genet 2014 Sep 18;12:1-11. Epub 2014 Apr 18.

Department of Criminal Justice Administration, California State University, East Bay, 4069 Meiklejohn Hall, 25800 Carlos Bee Boulevard, Hayward, CA 94542, United States.

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http://dx.doi.org/10.1016/j.fsigen.2014.04.003DOI Listing
September 2014

A model-based approach for identifying signatures of ancient balancing selection in genetic data.

PLoS Genet 2014 Aug 21;10(8):e1004561. Epub 2014 Aug 21.

Department of Integrative Biology, University of California, Berkeley, Berkeley, California, United States of America; Department of Statistics, University of California, Berkeley, Berkeley, California, United States of America; Department of Biology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1371/journal.pgen.1004561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140648PMC
August 2014

Evolution. On the origin of Peter Rabbit.

Science 2014 Aug;345(6200):1000-1

Department of Ecology and Evolutionary Biology, Interdepartmental Program in Bioinformatics, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1126/science.1258775DOI Listing
August 2014

Natural selection reduced diversity on human y chromosomes.

PLoS Genet 2014 Jan 9;10(1):e1004064. Epub 2014 Jan 9.

Statistics Department, University of California-Berkeley, Berkeley, California, United States of America ; Integrative Biology Department, University of California-Berkeley, Berkeley, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886894PMC
January 2014

Calculating the weight of evidence in low-template forensic DNA casework.

J Forensic Sci 2013 Jan 19;58 Suppl 1:S243-9. Epub 2012 Oct 19.

Department of Integrative Biology, University of California Berkeley, Berkeley, CA 94720-3140, USA.

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http://dx.doi.org/10.1111/1556-4029.12017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449098PMC
January 2013

Detecting directional selection in the presence of recent admixture in African-Americans.

Genetics 2011 Mar 31;187(3):823-35. Epub 2010 Dec 31.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1534/genetics.110.122739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063676PMC
March 2011

Graydon et al. provide no new evidence that forensic STR loci are functional.

Forensic Sci Int Genet 2010 Jul 2;4(4):273-4. Epub 2009 Oct 2.

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http://dx.doi.org/10.1016/j.fsigen.2009.09.006DOI Listing
July 2010

The effect of recent admixture on inference of ancient human population history.

Genetics 2010 Jun 9;185(2):611-22. Epub 2010 Apr 9.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1534/genetics.109.113761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881141PMC
June 2010

Detecting ancient admixture and estimating demographic parameters in multiple human populations.

Mol Biol Evol 2009 Aug 6;26(8):1823-7. Epub 2009 May 6.

Department of Epidemiology and Biostatistics, Institute for Human Genetics, University of California San Francisco, CA, USA.

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http://dx.doi.org/10.1093/molbev/msp096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734152PMC
August 2009

Methods for human demographic inference using haplotype patterns from genomewide single-nucleotide polymorphism data.

Genetics 2009 May 2;182(1):217-31. Epub 2009 Mar 2.

Department of Biostatistics and Computational Biology, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1534/genetics.108.099275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674818PMC
May 2009

Variants associated with common disease are not unusually differentiated in frequency across populations.

Am J Hum Genet 2006 Jan 16;78(1):130-6. Epub 2005 Nov 16.

Department of Biology, Georgetown University, Washington, DC 20057-1229, USA.

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http://dx.doi.org/10.1086/499287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1380210PMC
January 2006

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease.

Nat Genet 2003 Feb 13;33(2):177-82. Epub 2003 Jan 13.

Whitehead/Massachuetts Institute of Technology Center for Genome Research, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1038/ng1071DOI Listing
February 2003