Kirill V Tarasov

Kirill V Tarasov

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Kirill V Tarasov

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Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals.

Authors:
Raymond Noordam William J Young Reem Salman Jørgen K Kanters Marten E van den Berg Diana van Heemst Henry J Lin Sandhi Maria Barreto Mary L Biggs Ginevra Biino Eulalia Catamo Maria Pina Concas Jun Ding Daniel S Evans Luisa Foco Niels Grarup Leo-Pekka Lyytikäinen Massimo Mangino Hao Mei Peter J van der Most Martina Müller-Nurasyid Christopher P Nelson Yong Qian Linda Repetto M Abdullah Said Nabi Shah Katharina Schramm Pedro G Vidigal Stefan Weiss Jie Yao Nuno R Zilhao Jennifer A Brody Peter S Braund Marco Brumat Eric Campana Paraskevi Christofidou Mark J Caulfield Alessandro De Grandi Anna F Dominiczak Alex S F Doney Gudny Eiriksdottir Christina Ellervik Luana Giatti Martin Gögele Claus Graff Xiuqing Guo Pim van der Harst Peter K Joshi Mika Kähönen Bryan Kestenbaum Maria F Lima-Costa Allan Linneberg Arie C Maan Thomas Meitinger Sandosh Padmanabhan Cristian Pattaro Annette Peters Astrid Petersmann Peter Sever Mortiz F Sinner Xia Shen Alice Stanton Konstantin Strauch Elsayed Z Soliman Kirill V Tarasov Kent D Taylor Chris H L Thio André G Uitterlinden Simona Vaccargiu Melanie Waldenberger Antonietta Robino Adolfo Correa Francesco Cucca Steven R Cummings Marcus Dörr Giorgia Girotto Vilmundur Gudnason Torben Hansen Susan R Heckbert Christian R Juhl Stefan Kääb Terho Lehtimäki Yongmei Liu Paulo A Lotufo Colin N A Palmer Mario Pirastu Peter P Pramstaller Antonio Luiz P Ribeiro Jerome I Rotter Nilesh J Samani Harold Snieder Tim D Spector Bruno H Stricker Niek Verweij James F Wilson James G Wilson J Wouter Jukema Andrew Tinker Christopher H Newton-Cheh Nona Sotoodehnia Dennis O Mook-Kanamori Patricia B Munroe Helen R Warren

J Am Coll Cardiol 2019 Jun;73(24):3118-3131

Clinical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; National Institute for Health Research Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2019.03.519DOI Listing
June 2019

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

Authors:
Jessica van Setten Jennifer A Brody Yalda Jamshidi Brenton R Swenson Anne M Butler Harry Campbell Fabiola M Del Greco Daniel S Evans Quince Gibson Daniel F Gudbjartsson Kathleen F Kerr Bouwe P Krijthe Leo-Pekka Lyytikäinen Christian Müller Martina Müller-Nurasyid Ilja M Nolte Sandosh Padmanabhan Marylyn D Ritchie Antonietta Robino Albert V Smith Maristella Steri Toshiko Tanaka Alexander Teumer Stella Trompet Sheila Ulivi Niek Verweij Xiaoyan Yin David O Arnar Folkert W Asselbergs Joel S Bader John Barnard Josh Bis Stefan Blankenberg Eric Boerwinkle Yuki Bradford Brendan M Buckley Mina K Chung Dana Crawford Marcel den Hoed Josh C Denny Anna F Dominiczak Georg B Ehret Mark Eijgelsheim Patrick T Ellinor Stephan B Felix Oscar H Franco Lude Franke Tamara B Harris Hilma Holm Gandin Ilaria Annamaria Iorio Mika Kähönen Ivana Kolcic Jan A Kors Edward G Lakatta Lenore J Launer Honghuang Lin Henry J Lin Ruth J F Loos Steven A Lubitz Peter W Macfarlane Jared W Magnani Irene Mateo Leach Thomas Meitinger Braxton D Mitchell Thomas Munzel George J Papanicolaou Annette Peters Arne Pfeufer Peter P Pramstaller Olli T Raitakari Jerome I Rotter Igor Rudan Nilesh J Samani David Schlessinger Claudia T Silva Aldana Moritz F Sinner Jonathan D Smith Harold Snieder Elsayed Z Soliman Timothy D Spector David J Stott Konstantin Strauch Kirill V Tarasov Unnur Thorsteinsdottir Andre G Uitterlinden David R Van Wagoner Uwe Völker Henry Völzke Melanie Waldenberger Harm Jan Westra Philipp S Wild Tanja Zeller Alvaro Alonso Christy L Avery Stefania Bandinelli Emelia J Benjamin Francesco Cucca Marcus Dörr Luigi Ferrucci Paolo Gasparini Vilmundur Gudnason Caroline Hayward Susan R Heckbert Andrew A Hicks J Wouter Jukema Stefan Kääb Terho Lehtimäki Yongmei Liu Patricia B Munroe Afshin Parsa Ozren Polasek Bruce M Psaty Dan M Roden Renate B Schnabel Gianfranco Sinagra Kari Stefansson Bruno H Stricker Pim van der Harst Cornelia M van Duijn James F Wilson Sina A Gharib Paul I W de Bakker Aaron Isaacs Dan E Arking Nona Sotoodehnia

Nat Commun 2018 07 25;9(1):2904. Epub 2018 Jul 25.

Departments of Medicine and Epidemiology, Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, 98101, WA, USA.

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http://dx.doi.org/10.1038/s41467-018-04766-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060178PMC
July 2018

Basal Spontaneous Firing of Rabbit Sinoatrial Node Cells Is Regulated by Dual Activation of PDEs (Phosphodiesterases) 3 and 4.

Circ Arrhythm Electrophysiol 2018 06;11(6):e005896

Laboratory of Cardiovascular Science, Gerontology Research Center, National Institute on Aging, National Institutes of Health, Baltimore, MD.

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http://dx.doi.org/10.1161/CIRCEP.117.005896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025775PMC
June 2018

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Authors:
Georg B Ehret Teresa Ferreira Daniel I Chasman Anne U Jackson Ellen M Schmidt Toby Johnson Gudmar Thorleifsson Jian'an Luan Lousie A Donnelly Stavroula Kanoni Ann-Kristin Petersen Vasyl Pihur Rona J Strawbridge Dmitry Shungin Maria F Hughes Osorio Meirelles Marika Kaakinen Nabila Bouatia-Naji Kati Kristiansson Sonia Shah Marcus E Kleber Xiuqing Guo Leo-Pekka Lyytikäinen Cristiano Fava Niclas Eriksson Ilja M Nolte Patrik K Magnusson Elias L Salfati Loukianos S Rallidis Elizabeth Theusch Andrew J P Smith Lasse Folkersen Kate Witkowska Tune H Pers Roby Joehanes Stuart K Kim Lazaros Lataniotis Rick Jansen Andrew D Johnson Helen Warren Young Jin Kim Wei Zhao Ying Wu Bamidele O Tayo Murielle Bochud Devin Absher Linda S Adair Najaf Amin Dan E Arking Tomas Axelsson Damiano Baldassarre Beverley Balkau Stefania Bandinelli Michael R Barnes Inês Barroso Stephen Bevan Joshua C Bis Gyda Bjornsdottir Michael Boehnke Eric Boerwinkle Lori L Bonnycastle Dorret I Boomsma Stefan R Bornstein Morris J Brown Michel Burnier Claudia P Cabrera John C Chambers I-Shou Chang Ching-Yu Cheng Peter S Chines Ren-Hua Chung Francis S Collins John M Connell Angela Döring Jean Dallongeville John Danesh Ulf de Faire Graciela Delgado Anna F Dominiczak Alex S F Doney Fotios Drenos Sarah Edkins John D Eicher Roberto Elosua Stefan Enroth Jeanette Erdmann Per Eriksson Tonu Esko Evangelos Evangelou Alun Evans Tove Fall Martin Farrall Janine F Felix Jean Ferrières Luigi Ferrucci Myriam Fornage Terrence Forrester Nora Franceschini Oscar H Franco Duran Anders Franco-Cereceda Ross M Fraser Santhi K Ganesh He Gao Karl Gertow Francesco Gianfagna Bruna Gigante Franco Giulianini Anuj Goel Alison H Goodall Mark O Goodarzi Mathias Gorski Jürgen Gräßler Christopher Groves Vilmundur Gudnason Ulf Gyllensten Göran Hallmans Anna-Liisa Hartikainen Maija Hassinen Aki S Havulinna Caroline Hayward Serge Hercberg Karl-Heinz Herzig Andrew A Hicks Aroon D Hingorani Joel N Hirschhorn Albert Hofman Jostein Holmen Oddgeir Lingaas Holmen Jouke-Jan Hottenga Phil Howard Chao A Hsiung Steven C Hunt M Arfan Ikram Thomas Illig Carlos Iribarren Richard A Jensen Mika Kähönen Hyun Kang Sekar Kathiresan Brendan J Keating Kay-Tee Khaw Yun Kyoung Kim Eric Kim Mika Kivimaki Norman Klopp Genovefa Kolovou Pirjo Komulainen Jaspal S Kooner Gulum Kosova Ronald M Krauss Diana Kuh Zoltan Kutalik Johanna Kuusisto Kirsti Kvaløy Timo A Lakka Nanette R Lee I-Te Lee Wen-Jane Lee Daniel Levy Xiaohui Li Kae-Woei Liang Honghuang Lin Li Lin Jaana Lindström Stéphane Lobbens Satu Männistö Gabriele Müller Martina Müller-Nurasyid François Mach Hugh S Markus Eirini Marouli Mark I McCarthy Colin A McKenzie Pierre Meneton Cristina Menni Andres Metspalu Vladan Mijatovic Leena Moilanen May E Montasser Andrew D Morris Alanna C Morrison Antonella Mulas Ramaiah Nagaraja Narisu Narisu Kjell Nikus Christopher J O'Donnell Paul F O'Reilly Ken K Ong Fred Paccaud Cameron D Palmer Afshin Parsa Nancy L Pedersen Brenda W Penninx Markus Perola Annette Peters Neil Poulter Peter P Pramstaller Bruce M Psaty Thomas Quertermous Dabeeru C Rao Asif Rasheed N William N W R Rayner Frida Renström Rainer Rettig Kenneth M Rice Robert Roberts Lynda M Rose Jacques Rossouw Nilesh J Samani Serena Sanna Jouko Saramies Heribert Schunkert Sylvain Sebert Wayne H-H Sheu Young-Ah Shin Xueling Sim Johannes H Smit Albert V Smith Maria X Sosa Tim D Spector Alena Stančáková Alice Stanton Kathleen E Stirrups Heather M Stringham Johan Sundstrom Amy J Swift Ann-Christine Syvänen E-Shyong Tai Toshiko Tanaka Kirill V Tarasov Alexander Teumer Unnur Thorsteinsdottir Martin D Tobin Elena Tremoli Andre G Uitterlinden Matti Uusitupa Ahmad Vaez Dhananjay Vaidya Cornelia M van Duijn Erik P A van Iperen Ramachandran S Vasan Germaine C Verwoert Jarmo Virtamo Veronique Vitart Benjamin F Voight Peter Vollenweider Aline Wagner Louise V Wain Nicholas J Wareham Hugh Watkins Alan B Weder Harm-Jan Westra Rainford Wilks Tom Wilsgaard James F Wilson Tien Y Wong Tsun-Po Yang Jie Yao Loic Yengo Weihua Zhang Jing Hua Zhao Xiaofeng Zhu Pascal Bovet Richard S Cooper Karen L Mohlke Danish Saleheen Jong-Young Lee Paul Elliott Hinco J Gierman Cristen J Willer Lude Franke G Kees Hovingh Kent D Taylor George Dedoussis Peter Sever Andrew Wong Lars Lind Themistocles L Assimes Inger Njølstad Peter Eh Schwarz Claudia Langenberg Harold Snieder Mark J Caulfield Olle Melander Markku Laakso Juha Saltevo Rainer Rauramaa Jaakko Tuomilehto Erik Ingelsson Terho Lehtimäki Kristian Hveem Walter Palmas Winfried März Meena Kumari Veikko Salomaa Yii-Der I Chen Jerome I Rotter Philippe Froguel Marjo-Riitta Jarvelin Edward G Lakatta Kari Kuulasmaa Paul W Franks Anders Hamsten H-Erich Wichmann Colin N A Palmer Kari Stefansson Paul M Ridker Ruth J F Loos Aravinda Chakravarti Panos Deloukas Andrew P Morris Christopher Newton-Cheh Patricia B Munroe

Nat Genet 2016 10 12;48(10):1171-1184. Epub 2016 Sep 12.

Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.

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http://dx.doi.org/10.1038/ng.3667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042863PMC
October 2016

52 Genetic Loci Influencing Myocardial Mass.

Authors:
Pim van der Harst Jessica van Setten Niek Verweij Georg Vogler Lude Franke Matthew T Maurano Xinchen Wang Irene Mateo Leach Mark Eijgelsheim Nona Sotoodehnia Caroline Hayward Rossella Sorice Osorio Meirelles Leo-Pekka Lyytikäinen Ozren Polašek Toshiko Tanaka Dan E Arking Sheila Ulivi Stella Trompet Martina Müller-Nurasyid Albert V Smith Marcus Dörr Kathleen F Kerr Jared W Magnani Fabiola Del Greco M Weihua Zhang Ilja M Nolte Claudia T Silva Sandosh Padmanabhan Vinicius Tragante Tõnu Esko Gonçalo R Abecasis Michiel E Adriaens Karl Andersen Phil Barnett Joshua C Bis Rolf Bodmer Brendan M Buckley Harry Campbell Megan V Cannon Aravinda Chakravarti Lin Y Chen Alessandro Delitala Richard B Devereux Pieter A Doevendans Anna F Dominiczak Luigi Ferrucci Ian Ford Christian Gieger Tamara B Harris Eric Haugen Matthias Heinig Dena G Hernandez Hans L Hillege Joel N Hirschhorn Albert Hofman Norbert Hubner Shih-Jen Hwang Annamaria Iorio Mika Kähönen Manolis Kellis Ivana Kolcic Ishminder K Kooner Jaspal S Kooner Jan A Kors Edward G Lakatta Kasper Lage Lenore J Launer Daniel Levy Alicia Lundby Peter W Macfarlane Dalit May Thomas Meitinger Andres Metspalu Stefania Nappo Silvia Naitza Shane Neph Alex S Nord Teresa Nutile Peter M Okin Jesper V Olsen Ben A Oostra Josef M Penninger Len A Pennacchio Tune H Pers Siegfried Perz Annette Peters Yigal M Pinto Arne Pfeufer Maria Grazia Pilia Peter P Pramstaller Bram P Prins Olli T Raitakari Soumya Raychaudhuri Ken M Rice Elizabeth J Rossin Jerome I Rotter Sebastian Schafer David Schlessinger Carsten O Schmidt Jobanpreet Sehmi Herman H W Silljé Gianfranco Sinagra Moritz F Sinner Kamil Slowikowski Elsayed Z Soliman Timothy D Spector Wilko Spiering John A Stamatoyannopoulos Ronald P Stolk Konstantin Strauch Sian-Tsung Tan Kirill V Tarasov Bosco Trinh Andre G Uitterlinden Malou van den Boogaard Cornelia M van Duijn Wiek H van Gilst Jorma S Viikari Peter M Visscher Veronique Vitart Uwe Völker Melanie Waldenberger Christian X Weichenberger Harm-Jan Westra Cisca Wijmenga Bruce H Wolffenbuttel Jian Yang Connie R Bezzina Patricia B Munroe Harold Snieder Alan F Wright Igor Rudan Laurie A Boyer Folkert W Asselbergs Dirk J van Veldhuisen Bruno H Stricker Bruce M Psaty Marina Ciullo Serena Sanna Terho Lehtimäki James F Wilson Stefania Bandinelli Alvaro Alonso Paolo Gasparini J Wouter Jukema Stefan Kääb Vilmundur Gudnason Stephan B Felix Susan R Heckbert Rudolf A de Boer Christopher Newton-Cheh Andrew A Hicks John C Chambers Yalda Jamshidi Axel Visel Vincent M Christoffels Aaron Isaacs Nilesh J Samani Paul I W de Bakker

J Am Coll Cardiol 2016 09;68(13):1435-1448

Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Epidemiology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.jacc.2016.07.729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478167PMC
September 2016

Longitudinal perspective on the conundrum of central arterial stiffness, blood pressure, and aging.

Hypertension 2014 Dec 15;64(6):1219-27. Epub 2014 Sep 15.

From the Hospital San Raffaele Pisana-Istituto Ricovero e Cura a Carattere Sceintifico (IRCCS), Rome, Italy (A.S.); Laboratory of Cardiovascular Science, National Institute of Aging, Baltimore, MD (C.H.M., J.B.S., K.V.T., H.S., E.G.L.); Loyola University Maryland, Baltimore (C.H.M.); Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy (M.O., L.A.P.F., F.L., M.G.P., A.D.); Johns Hopkins School of Medicine, Baltimore, MD (M.A.); and MedStar Heart Institute, Washington, DC (S.S.N.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231012PMC
December 2014

Adrenomedullin and arterial stiffness: integrative approach combining monocyte ADM expression, plasma MR-Pro-ADM, and genome-wide association study.

Circ Cardiovasc Genet 2014 Oct 22;7(5):634-41. Epub 2014 Jul 22.

From UMR_S 1166, Sorbonne Universités UPMC Université Paris 06, UMR_S 1166 INSERM, UMR_S 1166 ICAN Institute for Cardiometabolism and Nutrition, Paris, France (F.B., M.G., R.C., G.M., D.-A.T., F.C., L.T.); Department of Cardiology, Caen University Hospital, Caen, France (F.B.); Department of Medicine II (P.S.W., T.M.), Center for Thrombosis and Hemostasis (P.S.W.), Institute for Clinical Chemistry and Laboratory Medicine (K.J.L.), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany (T.Z., S.B.); Institut de Cardiologie, Centre Hospitalier Universitaire Pitié-Salpêtriėre (ACTION Group, AP-HP, Université Paris 6), Paris, France (G.M.); Cardiovascular Engineering, Inc, Norwood, MA (G.F.M.); Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands (G.C.V.); and Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD (K.V.T.).

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http://dx.doi.org/10.1161/CIRCGENETICS.113.000456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865635PMC
October 2014

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

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http://dx.doi.org/10.1038/ng.3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124521PMC
August 2014

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Authors:
Maria Sabater-Lleal Jie Huang Daniel Chasman Silvia Naitza Abbas Dehghan Andrew D Johnson Alexander Teumer Alex P Reiner Lasse Folkersen Saonli Basu Alicja R Rudnicka Stella Trompet Anders Mälarstig Jens Baumert Joshua C Bis Xiuqing Guo Jouke J Hottenga So-Youn Shin Lorna M Lopez Jari Lahti Toshiko Tanaka Lisa R Yanek Tiphaine Oudot-Mellakh James F Wilson Pau Navarro Jennifer E Huffman Tatijana Zemunik Susan Redline Reena Mehra Drazen Pulanic Igor Rudan Alan F Wright Ivana Kolcic Ozren Polasek Sarah H Wild Harry Campbell J David Curb Robert Wallace Simin Liu Charles B Eaton Diane M Becker Lewis C Becker Stefania Bandinelli Katri Räikkönen Elisabeth Widen Aarno Palotie Myriam Fornage David Green Myron Gross Gail Davies Sarah E Harris David C Liewald John M Starr Frances M K Williams Peter J Grant Timothy D Spector Rona J Strawbridge Angela Silveira Bengt Sennblad Fernando Rivadeneira Andre G Uitterlinden Oscar H Franco Albert Hofman Jenny van Dongen Gonneke Willemsen Dorret I Boomsma Jie Yao Nancy Swords Jenny Talin Haritunians Barbara McKnight Thomas Lumley Kent D Taylor Jerome I Rotter Bruce M Psaty Annette Peters Christian Gieger Thomas Illig Anne Grotevendt Georg Homuth Henry Völzke Thomas Kocher Anuj Goel Maria Grazia Franzosi Udo Seedorf Robert Clarke Maristella Steri Kirill V Tarasov Serena Sanna David Schlessinger David J Stott Naveed Sattar Brendan M Buckley Ann Rumley Gordon D Lowe Wendy L McArdle Ming-Huei Chen Geoffrey H Tofler Jaejoon Song Eric Boerwinkle Aaron R Folsom Lynda M Rose Anders Franco-Cereceda Martina Teichert M Arfan Ikram Thomas H Mosley Steve Bevan Martin Dichgans Peter M Rothwell Cathie L M Sudlow Jemma C Hopewell John C Chambers Danish Saleheen Jaspal S Kooner John Danesh Christopher P Nelson Jeanette Erdmann Muredach P Reilly Sekar Kathiresan Heribert Schunkert Pierre-Emmanuel Morange Luigi Ferrucci Johan G Eriksson David Jacobs Ian J Deary Nicole Soranzo Jacqueline C M Witteman Eco J C de Geus Russell P Tracy Caroline Hayward Wolfgang Koenig Francesco Cucca J Wouter Jukema Per Eriksson Sudha Seshadri Hugh S Markus Hugh Watkins Nilesh J Samani Henri Wallaschofski Nicholas L Smith David Tregouet Paul M Ridker Weihong Tang David P Strachan Anders Hamsten Christopher J O'Donnell

Circulation 2013 Sep 22;128(12):1310-24. Epub 2013 Aug 22.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842025PMC
September 2013

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

Authors:
Marcel den Hoed Mark Eijgelsheim Tõnu Esko Bianca J J M Brundel David S Peal David M Evans Ilja M Nolte Ayellet V Segrè Hilma Holm Robert E Handsaker Harm-Jan Westra Toby Johnson Aaron Isaacs Jian Yang Alicia Lundby Jing Hua Zhao Young Jin Kim Min Jin Go Peter Almgren Murielle Bochud Gabrielle Boucher Marilyn C Cornelis Daniel Gudbjartsson David Hadley Pim van der Harst Caroline Hayward Martin den Heijer Wilmar Igl Anne U Jackson Zoltán Kutalik Jian'an Luan John P Kemp Kati Kristiansson Claes Ladenvall Mattias Lorentzon May E Montasser Omer T Njajou Paul F O'Reilly Sandosh Padmanabhan Beate St Pourcain Tuomo Rankinen Perttu Salo Toshiko Tanaka Nicholas J Timpson Veronique Vitart Lindsay Waite William Wheeler Weihua Zhang Harmen H M Draisma Mary F Feitosa Kathleen F Kerr Penelope A Lind Evelin Mihailov N Charlotte Onland-Moret Ci Song Michael N Weedon Weijia Xie Loic Yengo Devin Absher Christine M Albert Alvaro Alonso Dan E Arking Paul I W de Bakker Beverley Balkau Cristina Barlassina Paola Benaglio Joshua C Bis Nabila Bouatia-Naji Søren Brage Stephen J Chanock Peter S Chines Mina Chung Dawood Darbar Christian Dina Marcus Dörr Paul Elliott Stephan B Felix Krista Fischer Christian Fuchsberger Eco J C de Geus Philippe Goyette Vilmundur Gudnason Tamara B Harris Anna-Liisa Hartikainen Aki S Havulinna Susan R Heckbert Andrew A Hicks Albert Hofman Suzanne Holewijn Femke Hoogstra-Berends Jouke-Jan Hottenga Majken K Jensen Asa Johansson Juhani Junttila Stefan Kääb Bart Kanon Shamika Ketkar Kay-Tee Khaw Joshua W Knowles Angrad S Kooner Jan A Kors Meena Kumari Lili Milani Päivi Laiho Edward G Lakatta Claudia Langenberg Maarten Leusink Yongmei Liu Robert N Luben Kathryn L Lunetta Stacey N Lynch Marcello R P Markus Pedro Marques-Vidal Irene Mateo Leach Wendy L McArdle Steven A McCarroll Sarah E Medland Kathryn A Miller Grant W Montgomery Alanna C Morrison Martina Müller-Nurasyid Pau Navarro Mari Nelis Jeffrey R O'Connell Christopher J O'Donnell Ken K Ong Anne B Newman Annette Peters Ozren Polasek Anneli Pouta Peter P Pramstaller Bruce M Psaty Dabeeru C Rao Susan M Ring Elizabeth J Rossin Diana Rudan Serena Sanna Robert A Scott Jaban S Sehmi Stephen Sharp Jordan T Shin Andrew B Singleton Albert V Smith Nicole Soranzo Tim D Spector Chip Stewart Heather M Stringham Kirill V Tarasov André G Uitterlinden Liesbeth Vandenput Shih-Jen Hwang John B Whitfield Cisca Wijmenga Sarah H Wild Gonneke Willemsen James F Wilson Jacqueline C M Witteman Andrew Wong Quenna Wong Yalda Jamshidi Paavo Zitting Jolanda M A Boer Dorret I Boomsma Ingrid B Borecki Cornelia M van Duijn Ulf Ekelund Nita G Forouhi Philippe Froguel Aroon Hingorani Erik Ingelsson Mika Kivimaki Richard A Kronmal Diana Kuh Lars Lind Nicholas G Martin Ben A Oostra Nancy L Pedersen Thomas Quertermous Jerome I Rotter Yvonne T van der Schouw W M Monique Verschuren Mark Walker Demetrius Albanes David O Arnar Themistocles L Assimes Stefania Bandinelli Michael Boehnke Rudolf A de Boer Claude Bouchard W L Mark Caulfield John C Chambers Gary Curhan Daniele Cusi Johan Eriksson Luigi Ferrucci Wiek H van Gilst Nicola Glorioso Jacqueline de Graaf Leif Groop Ulf Gyllensten Wen-Chi Hsueh Frank B Hu Heikki V Huikuri David J Hunter Carlos Iribarren Bo Isomaa Marjo-Riitta Jarvelin Antti Jula Mika Kähönen Lambertus A Kiemeney Melanie M van der Klauw Jaspal S Kooner Peter Kraft Licia Iacoviello Terho Lehtimäki Marja-Liisa L Lokki Braxton D Mitchell Gerjan Navis Markku S Nieminen Claes Ohlsson Neil R Poulter Lu Qi Olli T Raitakari Eric B Rimm John D Rioux Federica Rizzi Igor Rudan Veikko Salomaa Peter S Sever Denis C Shields Alan R Shuldiner Juha Sinisalo Alice V Stanton Ronald P Stolk David P Strachan Jean-Claude Tardif Unnur Thorsteinsdottir Jaako Tuomilehto Dirk J van Veldhuisen Jarmo Virtamo Jorma Viikari Peter Vollenweider Gérard Waeber Elisabeth Widen Yoon Shin Cho Jesper V Olsen Peter M Visscher Cristen Willer Lude Franke Jeanette Erdmann John R Thompson Arne Pfeufer Nona Sotoodehnia Christopher Newton-Cheh Patrick T Ellinor Bruno H Ch Stricker Andres Metspalu Markus Perola Jacques S Beckmann George Davey Smith Kari Stefansson Nicholas J Wareham Patricia B Munroe Ody C M Sibon David J Milan Harold Snieder Nilesh J Samani Ruth J F Loos

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