Kimmo Kontula

Kimmo Kontula

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Kimmo Kontula

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Genome-wide association study of white-coat effect in hypertensive patients.

Blood Press 2019 08 2;28(4):239-249. Epub 2019 May 2.

a Research Program for Clinical and Molecular Metabolism, Faculty of Medicine , University of Helsinki.

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http://dx.doi.org/10.1080/08037051.2019.1604066DOI Listing
August 2019

Effect of hydrochlorothiazide on serum uric acid concentration: a genome-wide association study.

Pharmacogenomics 2018 04 27;19(6):517-527. Epub 2018 Mar 27.

Department of Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.2217/pgs-2017-0184DOI Listing
April 2018

The genetics underlying idiopathic ventricular fibrillation: A special role for catecholaminergic polymorphic ventricular tachycardia?

Int J Cardiol 2018 Jan 5;250:139-145. Epub 2017 Oct 5.

Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.10.016DOI Listing
January 2018

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.

Nat Genet 2017 Feb 19;49(2):269-273. Epub 2016 Dec 19.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.3745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540332PMC
February 2017

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

Hypertension 2017 01 31;69(1):51-59. Epub 2016 Oct 31.

From the Department of Health Sciences, University of Milan, Italy (E.S., F.R., M.C., M.B., C.B.); Human Genetics and Institute of Molecular Medicine, University of Texas Health Science Center, Houston (Z.W., E.B.); Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, College of Pharmacy (Y.G., C.W.M., J.A.J., R.M.C.-D.) and Division of Cardiovascular Medicine, Department of Medicine (J.A.J., R.M.C.-D.), University of Florida, Gainesville; Institute of Cardiovascular and Medical Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, United Kingdom (S.P., A.F.D.); Department of Medicine, University of Helsinki and Helsinki University Hospital, Finland (T.P.H., K.K.K.); Nephrology and Dialysis and Hypertension Unit, San Raffaele Scientific Institute, Università Vita Salute San Raffaele, Milano, Italy (C.L., P.M.); Hypertension and Related Disease Centre, AOU-University of Sassari, Italy (R.Z., N.G.); Division of Biomedical Statistics and Informatics, Department of Health Sciences Research (K.R.B.) and Division of Nephrology and Hypertension, Department of Internal Medicine (S.T.T.), Mayo Clinic, Rochester, Minnesota; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland (A.-P.S); Department of Clinical Sciences, Lund University, Malmö, Sweden (O.M.); Section of Nephrology, Department of Medicine, University of Chicago, Illinois (A.B.C.); Institute of Biomedical Technologies, National Research Centre of Italy, Segrate, Milan, Italy (D.C.); and Sanipedia srl, Bresso, Italy (D.C.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145728PMC
January 2017

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Nat Commun 2016 08 9;7:12342. Epub 2016 Aug 9.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1038/ncomms12342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980482PMC
August 2016

Genetic Modifiers for the Long-QT Syndrome: How Important Is the Role of Variants in the 3' Untranslated Region of KCNQ1?

Circ Cardiovasc Genet 2016 Aug;9(4):330-9

From the Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan (L.C., C.S., P.J.S.); Department of Molecular Medicine (L.C.) and Department of Public Health (M.C.M., C.M.), Unit of Biostatistics and Clinical Epidemiology, University of Pavia, Pavia; Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital IRCCS Istituto Auxologico Italiano, Milan, Italy (L.C., G.P.); Department of Medicine, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland (A.M.L., K.K.); Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany (E.M., P.L., T.M.); Department of Medicine and Surgery University of Milano-Bicocca, Milan, Italy (G.P.); Department of Internal Medicine, University of Stellenbosch, South Africa (M.H., A.G., P.A.B.); Institute of Human Genetics, Technische Universität München (T.M.); DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (T.M.); and Heart and Lung Center, Helsinki University Central Hospital, Helsinki, Finland (H.S.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001419DOI Listing
August 2016

Antiarrhythmic Action of Flecainide in Polymorphic Ventricular Arrhythmias Caused by a Gain-of-Function Mutation in the Nav 1.5 Sodium Channel.

Ann Noninvasive Electrocardiol 2016 Jul 7;21(4):343-51. Epub 2015 Oct 7.

Department of Clinical Research, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1111/anec.12312DOI Listing
July 2016

Endoplasmic reticulum stress increases AT1R mRNA expression via TIA-1-dependent mechanism.

Nucleic Acids Res 2016 Apr 17;44(7):3095-104. Epub 2015 Dec 17.

Department of Medicine, University of Helsinki, Helsinki, FIN-00014, Finland Heart and Lung Center, Department of Cardiology, Helsinki University Central Hospital, Helsinki, FIN-00029, Finland

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http://dx.doi.org/10.1093/nar/gkv1368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838341PMC
April 2016

Prediction of sudden cardiac death with automated high-throughput analysis of heterogeneity in standard resting 12-lead electrocardiograms.

Heart Rhythm 2016 Mar 23;13(3):713-20. Epub 2015 Nov 23.

Beth Israel Deaconess Medical Center, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2015.11.035DOI Listing
March 2016

Antiarrhythmic Effects of Dantrolene in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia and Replication of the Responses Using iPSC Models.

PLoS One 2015 8;10(5):e0125366. Epub 2015 May 8.

BioMediTech, University of Tampere, Tampere, Finland; School of Medicine, University of Tampere, Tampere, Finland; Heart Hospital, Tampere University Hospital, Tampere, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125366PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425399PMC
February 2016

PTPRD gene associated with blood pressure response to atenolol and resistant hypertension.

J Hypertens 2015 Nov;33(11):2278-85

aDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida, Gainesville, Florida USA bDepartment of Medicine and Program in Personalized and Genomic Medicine, University of Maryland, Baltimore, Maryland, USA cDepartment of Medicine, University of Helsinki, and University Central Hospital of Helsinki, Helsinki, Finland dBHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK eDepartment of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA fInstitute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland. gCollege of Medicine, Mayo Clinic Rochester, Rochester, Minnesota USA hCenter for Human Genetics, University of Texas at Houston, Houston, Texas, USA iRIKEN Center for Integrative Medical Sciences, Yokohama, Japan jSchool of Medicine, Emory University, Atlanta, Georgia, USA kDivision of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA.

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http://pdfs.journals.lww.com/jhypertension/2015/11000/PTPRD_
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http://dx.doi.org/10.1097/HJH.0000000000000714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788379PMC
November 2015

Follow-up of 316 molecularly defined pediatric long-QT syndrome patients: clinical course, treatments, and side effects.

Circ Arrhythm Electrophysiol 2015 Aug 10;8(4):815-23. Epub 2015 Jun 10.

From the Heart and Lung Center, Helsinki University Central Hospital (M.K., A.M., M.V., L.T., H.S.), Children's Hospital, Helsinki University Central Hospital (A.H., J.-M.H.), Department of Medicine, Helsinki University Central Hospital (A.M.L., K.K.), and Institute of Behavioural Sciences, Psychology (T.H.), University of Helsinki, Helsinki, Finland; and Department of Health, National Institute for Health and Welfare, Helsinki, Finland (A.S.H., V.S.).

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http://dx.doi.org/10.1161/CIRCEP.114.002654DOI Listing
August 2015

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

J Hypertens 2015 Jun;33(6):1301-9

aDepartment of Health Sciences, University of Milan at San Paolo Hospital, and Filarete Foundation, Genomic and Bioinformatics Unit, Milan bHypertension and Related Disease Centre, AOU-University of Sassari, Sassari cUniversità Vita Salute San Raffaele, Nephrology and Dialysis and Hypertension Unit, San Raffaele Scientific Institute, Milan, Italy dDepartment of Medicine, University of Helsinki and Helsinki University Central Hospital eInstitute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland fDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota gHuman Genetics and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas hRenal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA iInstitute of Cardiovascular and Medical Sciences, College of Medicine Veterinary and Life Sciences, University of Glasgow, Glasgow, UK jDepartment of Clinical Sciences, Lund University, Malmö, Sweden kDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida, USA lRespiratory Medicine Unit, Department of Medicine and CMM, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden mDepartment of Medical Biotechnologies and Translational Medicine, University of Milan, and Humanitas Clinical and Research Center, University of Milan, and National Research Council of Italy, Rozzano (MI) nDepartment of Clinical Medicine, Cardiovascular and Immunological Sciences, University of Naples 'Federico II', Naples, Italy *Martina Chittani and Roberta Zaninello contributed equally to the writing of this article.

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http://dx.doi.org/10.1097/HJH.0000000000000541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484731PMC
June 2015

Prevalence and clinical correlates of familial hypercholesterolemia founder mutations in the general population.

Atherosclerosis 2015 Jan 18;238(1):64-9. Epub 2014 Nov 18.

Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.11.015DOI Listing
January 2015

Gain-of-function mutation of the SCN5A gene causes exercise-induced polymorphic ventricular arrhythmias.

Circ Cardiovasc Genet 2014 Dec 10;7(6):771-81. Epub 2014 Sep 10.

From the Heart and Lung Center, Helsinki University Central Hospital, Helsinki, Finland (H.S., A.M., L.T.); Department of Clinical Research (M.Y.A., H.A), and Department of Physiology (J.P.K), University of Bern, Bern, Switzerland. and Institute for Molecular Medicine Finland (FIMM), University of Helsinki (J.L., A.P., E.W.), and Department of Medicine, University of Helsinki and Helsinki University Central Hospital (P.J.L.-F., A.M.L., K.K.), Helsinki, Finland.

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000703DOI Listing
December 2014

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

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http://dx.doi.org/10.1038/ng.3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124521PMC
August 2014

Telomere length is associated with ACE I/D polymorphism in hypertensive patients with left ventricular hypertrophy.

J Renin Angiotensin Aldosterone Syst 2013 Sep 17;14(3):227-34. Epub 2012 Oct 17.

Minerva Institute for Medical Research, Finland.

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http://dx.doi.org/10.1177/1470320312460292DOI Listing
September 2013

Stress proneness in molecularly defined long QT syndrome: a study using temperament assessment by behavioural inhibition system scale.

Stress Health 2013 Apr 30;29(2):150-5. Epub 2012 Aug 30.

IBS, Unit of Personality, Work and Health Psychology, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/smi.2441DOI Listing
April 2013

Regulation of AT1R expression through HuR by insulin.

Nucleic Acids Res 2012 Jul 23;40(12):5250-61. Epub 2012 Feb 23.

Research Program for Molecular Medicine, Biomedicum Helsinki, FIN-00014 University of Helsinki, Finland.

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http://dx.doi.org/10.1093/nar/gks170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384301PMC
July 2012

Clinical and molecular approaches to individualize antihypertensive drug therapy.

Ann Med 2012 Jun;44 Suppl 1:S23-9

Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.3109/07853890.2012.679960DOI Listing
June 2012

Intravenous epinephrine infusion test in diagnosis of catecholaminergic polymorphic ventricular tachycardia.

J Cardiovasc Electrophysiol 2012 Feb 28;23(2):194-9. Epub 2011 Sep 28.

Research Program in Molecular Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1111/j.1540-8167.2011.02188.xDOI Listing
February 2012

STK39 variation predicts the ambulatory blood pressure response to losartan in hypertensive men.

Hypertens Res 2012 Jan 13;35(1):107-14. Epub 2011 Oct 13.

Department of Medicine, and Research Program for Molecular Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/hr.2011.166DOI Listing
January 2012

Cloninger's temperament traits and inherited long QT syndrome.

J Psychosom Res 2011 Oct 22;71(4):245-9. Epub 2011 Apr 22.

Institute of Behavioral Sciences, Psychology, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jpsychores.2011.03.010DOI Listing
October 2011

Population-prevalent desmosomal mutations predisposing to arrhythmogenic right ventricular cardiomyopathy.

Heart Rhythm 2011 Aug 10;8(8):1214-21. Epub 2011 Mar 10.

Research Program for Molecular Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.hrthm.2011.03.015DOI Listing
August 2011

Common genetic variants, QT interval, and sudden cardiac death in a Finnish population-based study.

Circ Cardiovasc Genet 2011 Jun 21;4(3):305-11. Epub 2011 Apr 21.

Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.110.959049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119024PMC
June 2011

Ryanodine receptor (RyR2) mutations in sudden cardiac death: studies in extended pedigrees and phenotypic characterization in vitro.

Int J Cardiol 2011 Mar 25;147(2):246-52. Epub 2009 Sep 25.

Research Program for Molecular Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.ijcard.2009.08.041DOI Listing
March 2011

Depressive symptoms in the congenital long QT syndrome.

Ann Med 2009 ;41(7):516-21

Department of Psychology, University of Helsinki, FIN-00014, Helsinki, Finland.

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http://dx.doi.org/10.1080/07853890903037254DOI Listing
January 2011

KCNE1 D85N polymorphism--a sex-specific modifier in type 1 long QT syndrome?

BMC Med Genet 2011 Jan 18;12:11. Epub 2011 Jan 18.

Research Program for Molecular Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1186/1471-2350-12-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032654PMC
January 2011

Common genetic variation of beta1- and beta2-adrenergic receptor and response to four classes of antihypertensive treatment.

Pharmacogenet Genomics 2010 May;20(5):342-5

Department of Medicine, University of Helsinki, and Research Program for Molecular Medicine, Biomedicum Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1097/FPC.0b013e328338e1b8DOI Listing
May 2010

CYP2C9 genotype modifies activity of the renin-angiotensin-aldosterone system in hypertensive men.

J Hypertens 2009 Oct;27(10):2001-9

Department of Medicine, University of Helsinki, FIN-00029 Helsinki, Finland.

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http://dx.doi.org/10.1097/HJH.0b013e32832f4faeDOI Listing
October 2009

Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study.

Am J Hypertens 2009 Feb 4;22(2):169-75. Epub 2008 Dec 4.

Department of Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/ajh.2008.343DOI Listing
February 2009

U-waves and T-wave peak to T-wave end intervals in patients with catecholaminergic polymorphic ventricular tachycardia, effects of beta-blockers.

Heart Rhythm 2008 Oct 12;5(10):1382-8. Epub 2008 Jun 12.

Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.hrthm.2008.06.011DOI Listing
October 2008

Further evidence for the role of ENPP1 in obesity: association with morbid obesity in Finns.

Obesity (Silver Spring) 2008 Sep;16(9):2113-9

Department of Medicine and Research Program for Molecular Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/oby.2008.313DOI Listing
September 2008

p100 increases AT1R expression through interaction with AT1R 3'-UTR.

Nucleic Acids Res 2008 Aug 4;36(13):4474-87. Epub 2008 Jul 4.

Research Program for Molecular Medicine, Biomedicum Helsinki, University of Helsinki, Finland.

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http://dx.doi.org/10.1093/nar/gkn411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490763PMC
August 2008

Plakophilin-2 missense mutations in arrhythmogenic right ventricular cardiomyopathy.

Int J Cardiol 2008 May 22;126(1):92-100. Epub 2007 May 22.

Research Program for Molecular Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.ijcard.2007.03.137DOI Listing
May 2008

[Not Available].

Duodecim 2006 ;122(14):1781-5

HYKS-instituutti Oy, HUS.

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April 2008

[Not Available].

Authors:
Kimmo Kontula

Duodecim 2007 ;123(1):5-6

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April 2008

Characterization of familial and sporadic arrhythmogenic right ventricular cardiomyopathy in Finland.

Ann Med 2007 ;39(4):312-8

Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1080/07853890701282003DOI Listing
August 2007

Beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome.

Int J Cardiol 2007 May 4;118(2):197-202. Epub 2006 Oct 4.

Department of Medicine, University of Helsinki, 00290 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.ijcard.2006.06.050DOI Listing
May 2007

Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.

Heart Rhythm 2007 May 18;4(5):603-7. Epub 2007 Jan 18.

Research Program in Molecular Medicine, Biomedicum Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.hrthm.2007.01.019DOI Listing
May 2007

Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients.

Ann Med 2006 ;38(4):294-304

Biomedicum Helsinki and Department of Medicine, University of Helsinki, Finland, and Service of Cardiology, University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.1080/07853890600756065DOI Listing
December 2006

A two-base deletion -439delGC in the melanocortin-4 receptor promoter associated with early-onset obesity.

Horm Res 2006 19;66(2):61-9. Epub 2006 May 19.

Department of Medicine and Research Program in Molecular Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1159/000093469DOI Listing
September 2006

[Finnish type mutations leading to heart disorders].

Authors:
Kimmo Kontula

Duodecim 2005 ;121(24):2665-79

Helsingin yliopisto, kliininen laitos, sisätautien osato, Helsinki.

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August 2006

[Finnish Medical Society Duodecim-125 years promoting health of Finns].

Authors:
Kimmo Kontula

Duodecim 2006 ;122(1):4-6

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August 2006

Family and twin studies in inflammatory bowel disease.

World J Gastroenterol 2006 Jun;12(23):3668-72

Department of Transplantation and Liver Surgery, Helsinki University Hospital, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087458PMC
http://dx.doi.org/10.3748/wjg.v12.i23.3668DOI Listing
June 2006

SCN5A mutation associated with cardiac conduction defect and atrial arrhythmias.

J Cardiovasc Electrophysiol 2006 May;17(5):480-5

Department of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

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May 2006

Screening of tumor necrosis factor receptor-associated factor 6 as a candidate gene for inflammatory bowel disease.

Scand J Gastroenterol 2006 Apr;41(4):424-9

Research Program in Molecular Medicine, Biomedicum Helsinki, Helsinki, Finland.

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April 2006

Manifestation, management and molecular analysis of candidate genes in two rare cases of thyrotoxic hypokalemic periodic paralysis.

Horm Res 2005 24;63(3):139-44. Epub 2005 Mar 24.

Division of Endocrinology, Department of Medicine, University of Helsinki, Finland.

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August 2005

Catecholaminergic polymorphic ventricular tachycardia: recent mechanistic insights.

Cardiovasc Res 2005 Aug;67(3):379-87

Department of Medicine, University of Helsinki, 00290 Helsinki, Finland.

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August 2005

Genetic variant of lactase-persistent C/T-13910 is associated with bone fractures in very old age.

J Am Geriatr Soc 2005 Jan;53(1):79-82

Department of Medical Genetics, University of Helsinki, Helsinki, Finland.

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January 2005