Kimme L Hyrich

Kimme L Hyrich

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Kimme L Hyrich

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Cervical screening uptake and rates of cervical dysplasia in the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Laura Chadwick Lianne Kearsley-Fleet Nina Brown Kath D Watson Mark Lunt Deborah P M Symmons Kimme L Hyrich

Rheumatology (Oxford) 2020 Mar;59(3):559-567

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kez277DOI Listing
March 2020

Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity.

Authors:
Yi Pan Sam Norton James M Gwinnutt Lianne Kearsley-Fleet Deborah P M Symmons Mark Lunt Adam Young Kimme L Hyrich Suzanne M M Verstappen

PLoS One 2019 20;14(5):e0215999. Epub 2019 May 20.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215999PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527224PMC
January 2020

The predictors of and reasons for non-adherence in an observational cohort of patients with rheumatoid arthritis commencing methotrexate.

Authors:
Holly F Hope Kimme L Hyrich James Anderson James Bluett Jamie C Sergeant Anne Barton Lis Cordingley Suzanne M M Verstappen

Rheumatology (Oxford) 2020 Jan;59(1):213-223

NIHR Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kez274DOI Listing
January 2020

What can rheumatology expect from real-world data?

Authors:
Kimme L Hyrich Angela Zink

Rheumatology (Oxford) 2020 Jan;59(1):12-13

German Rheumatism Research Centre, Epidemiology Unit, Berlin, Germany.

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http://dx.doi.org/10.1093/rheumatology/kez366DOI Listing
January 2020

Real world data in rheumatology.

Authors:
Kimme L Hyrich

Semin Arthritis Rheum 2019 12;49(3S):S22-S24

Centre for Epidemiology Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester M13 9PT, UK; National Institute of Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2019.09.021DOI Listing
December 2019

Long-term outcomes of patients who rate symptoms of rheumatoid arthritis as 'satisfactory'.

Authors:
James M Gwinnutt Kimme L Hyrich Mark Lunt Anne Barton Suzanne M M Verstappen

Rheumatology (Oxford) 2019 Nov 15. Epub 2019 Nov 15.

Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre.

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http://dx.doi.org/10.1093/rheumatology/kez497DOI Listing
November 2019

Polypharmacy is associated with treatment response and serious adverse events: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Katie Bechman Benjamin D Clarke Andrew I Rutherford Mark Yates Elena Nikiphorou Mariam Molokhia Sam Norton Andrew P Cope Kimme L Hyrich James B Galloway

Rheumatology (Oxford) 2019 Oct;58(10):1767-1776

Department of Inflammation Biology, School of Immunology & Microbial Sciences.

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http://dx.doi.org/10.1093/rheumatology/kez037DOI Listing
October 2019

Predicting disease outcomes in juvenile idiopathic arthritis: challenges, evidence, and new directions.

Authors:
Stephanie J W Shoop-Worrall Qiong Wu Rebecca Davies Kimme L Hyrich Lucy R Wedderburn

Lancet Child Adolesc Health 2019 Oct 19;3(10):725-733. Epub 2019 Jul 19.

UCL Great Ormond Street Institute of Child Health, University College London, London, UK; Centre for Adolescent Rheumatology Versus Arthritis at University College London, University College London Hospital, and Great Ormond Street Hospital, University College London, London, UK; National Institute of Health Research Biomedical Research Centre at Great Ormond Street Hospital, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(19)30188-9DOI Listing
October 2019

Differential DNA methylation correlates with response to methotrexate in rheumatoid arthritis.

Authors:
Nisha Nair Darren Plant Suzanne M Verstappen John D Isaacs Ann W Morgan Kimme L Hyrich Anne Barton Anthony G Wilson

Rheumatology (Oxford) 2019 Oct 10. Epub 2019 Oct 10.

University College Dublin School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1093/rheumatology/kez411DOI Listing
October 2019

The risk of uveitis in patients with JIA receiving etanercept: the challenges of analysing real-world data.

Authors:
Rebecca Davies Diederik De Cock Lianne Kearsley-Fleet Taunton Southwood Eileen Baildam Michael W Beresford Helen E Foster Wendy Thomson Athimalaipet Ramanan Kimme L Hyrich

Rheumatology (Oxford) 2019 Oct 12. Epub 2019 Oct 12.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, The University of Manchester, Manchester Academic Health Science Centre, Manchester.

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http://dx.doi.org/10.1093/rheumatology/kez449DOI Listing
October 2019

A UK study: vocational experiences of young adults with juvenile idiopathic arthritis.

Authors:
Laura E Lunt Ailsa Bosworth Matthew Bezzant Karen Walker-Bone Kimme L Hyrich Wendy Thomson Janet E McDonagh Suzanne M M Verstappen

Pediatr Rheumatol Online J 2019 08 6;17(1):54. Epub 2019 Aug 6.

Centre for Epidemiology Versus Arthritis, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1186/s12969-019-0357-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683541PMC
August 2019

Predicting Remission Remains a Challenge in Patients with Juvenile Idiopathic Arthritis.

Authors:
Stephanie J W Shoop-Worrall Kimme L Hyrich

J Rheumatol 2019 Jun;46(6):552-554

Arthritis Research UK Centre for Epidemiology, The University of Manchester, and the UK National Institute for Health Research Manchester Biomedical Research Centre, Manchester University Hospitals, National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.3899/jrheum.181245DOI Listing
June 2019

Methotrexate persistence and adverse drug reactions in patients with juvenile idiopathic arthritis.

Authors:
Lianne Kearsley-Fleet Laura Vicente González Douglas Steinke Rebecca Davies Diederik De Cock Eileen Baildam Michael W Beresford Helen E Foster Taunton R Southwood Wendy Thomson Kimme L Hyrich

Rheumatology (Oxford) 2019 Mar 8. Epub 2019 Mar 8.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kez048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649753PMC
March 2019

Comparing Proxy, Adolescent and Adult Assessments of Functional Ability in Adolescents with Juvenile Idiopathic Arthritis.

Authors:
Stephanie Jw Shoop-Worrall Kimme L Hyrich Suzanne Mm Verstappen Jamie C Sergeant Eileen Baildam Alice Chieng Joyce Davidson Helen Foster Yiannis Ioannou Flora McErlane Lucy R Wedderburn Wendy Thomson Janet E McDonagh

Arthritis Care Res (Hoboken) 2019 Mar 15. Epub 2019 Mar 15.

NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1002/acr.23877DOI Listing
March 2019

Use and effectiveness of rituximab in children and young people with juvenile idiopathic arthritis in a cohort study in the United Kingdom.

Authors:
Lianne Kearsley-Fleet Sunil Sampath Liza J McCann Eileen Baildam Michael W Beresford Rebecca Davies Diederik De Cock Helen E Foster Taunton R Southwood Wendy Thomson Kimme L Hyrich

Rheumatology (Oxford) 2019 02;58(2):331-335

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/key306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343463PMC
February 2019

Malignancy and mortality rates in patients with severe psoriatic arthritis requiring tumour-necrosis factor alpha inhibition: results from the British Society for Rheumatology Biologics Register.

Authors:
Karen M Fagerli Lianne Kearsley-Fleet Louise K Mercer Kath Watson Jon Packham Deborah P M Symmons Kimme L Hyrich

Rheumatology (Oxford) 2019 01;58(1):80-85

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/key241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293477PMC
January 2019

Short-term outcomes in patients with systemic juvenile idiopathic arthritis treated with either tocilizumab or anakinra.

Authors:
Lianne Kearsley-Fleet Michael W Beresford Rebecca Davies Diederik De Cock Eileen Baildam Helen E Foster Taunton R Southwood Wendy Thomson Kimme L Hyrich

Rheumatology (Oxford) 2019 01;58(1):94-102

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/key262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293481PMC
January 2019

Characteristics of difficult-to-treat rheumatoid arthritis: results of an international survey.

Authors:
Nadia M T Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes W G Jacobs Paco M J Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob M van Laar György Nagy

Ann Rheum Dis 2018 12 7;77(12):1705-1709. Epub 2018 Sep 7.

Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2018-21368
Publisher Site
http://dx.doi.org/10.1136/annrheumdis-2018-213687DOI Listing
December 2018

Biologic refractory disease in rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Lianne Kearsley-Fleet Rebecca Davies Diederik De Cock Kath D Watson Mark Lunt Maya H Buch John D Isaacs Kimme L Hyrich

Ann Rheum Dis 2018 10 6;77(10):1405-1412. Epub 2018 Jul 6.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2018-213378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161665PMC
October 2018

Serious infection risk after 1 year between patients with rheumatoid arthritis treated with rituximab or with a second TNFi after initial TNFi failure: results from The British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Lucía Silva-Fernández Diederik De Cock Mark Lunt Audrey S Low Kath D Watson Deborah P M Symmons Kimme L Hyrich

Rheumatology (Oxford) 2018 09;57(9):1533-1540

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kex304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105920PMC
September 2018

Long-Term Outcomes Following Achievement of Clinically Inactive Disease in Juvenile Idiopathic Arthritis: The Importance of Definition.

Authors:
Stephanie J W Shoop-Worrall Suzanne M M Verstappen Janet E McDonagh Eileen Baildam Alice Chieng Joyce Davidson Helen Foster Yiannis Ioannou Flora McErlane Lucy R Wedderburn W Thomson Kimme L Hyrich

Arthritis Rheumatol 2018 09 22;70(9):1519-1529. Epub 2018 Jul 22.

The University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://doi.wiley.com/10.1002/art.40519
Publisher Site
http://dx.doi.org/10.1002/art.40519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175118PMC
September 2018

Growth patterns in early juvenile idiopathic arthritis: Results from the Childhood Arthritis Prospective Study (CAPS).

Authors:
Flora McErlane Roberto Carrasco Lianne Kearsley-Fleet Eileen M Baildam Lucy R Wedderburn Helen E Foster Yiannis Ioannou S E Alice Chieng Joyce E Davidson Wendy Thomson Kimme L Hyrich

Semin Arthritis Rheum 2018 08 7;48(1):53-60. Epub 2017 Nov 7.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Division of Musculoskeletal & Dermatological Sciences. Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089842PMC
August 2018

Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS).

Authors:
Jamie C Sergeant Kimme L Hyrich James Anderson Kamilla Kopec-Harding Holly F Hope Deborah P M Symmons Anne Barton Suzanne M M Verstappen

Arthritis Res Ther 2018 07 13;20(1):147. Epub 2018 Jul 13.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1186/s13075-018-1645-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044018PMC
July 2018

Opportunistic infections in rheumatoid arthritis patients exposed to biologic therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Andrew I Rutherford Eunice Patarata Sujith Subesinghe Kimme L Hyrich James B Galloway

Rheumatology (Oxford) 2018 06;57(6):997-1001

Academic Rheumatology Department, King's College London, London, UK.

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http://dx.doi.org/10.1093/rheumatology/key023DOI Listing
June 2018

Long-term persistence with rituximab in patients with rheumatoid arthritis.

Authors:
Alexander G S Oldroyd Deborah P M Symmons Jamie C Sergeant Lianne Kearsley-Fleet Kath Watson Mark Lunt Kimme L Hyrich

Rheumatology (Oxford) 2018 06;57(6):1089-1096

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/key036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965076PMC
June 2018

Serious infection across biologic-treated patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Andrew I Rutherford Sujith Subesinghe Kimme L Hyrich James B Galloway

Ann Rheum Dis 2018 06 28;77(6):905-910. Epub 2018 Mar 28.

Academic Rheumatology Department, King's College London, London, UK.

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http://dx.doi.org/10.1136/annrheumdis-2017-212825DOI Listing
June 2018

Patterns of pain over time among children with juvenile idiopathic arthritis.

Authors:
Amir Rashid Lis Cordingley Roberto Carrasco Helen E Foster Eileen M Baildam Alice Chieng Joyce E Davidson Lucy R Wedderburn Yiannis Ioannou Flora McErlane Suzanne M M Verstappen Kimme L Hyrich Wendy Thomson

Arch Dis Child 2018 05 25;103(5):437-443. Epub 2017 Nov 25.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1136/archdischild-2017-313337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916104PMC
May 2018

The relationship between depression and biologic treatment response in rheumatoid arthritis: An analysis of the British Society for Rheumatology Biologics Register.

Authors:
Faith Matcham Rebecca Davies Matthew Hotopf Kimme L Hyrich Sam Norton Sophia Steer James Galloway

Rheumatology (Oxford) 2018 05;57(5):835-843

Department of Academic Rheumatology, King's College London, London, UK.

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http://dx.doi.org/10.1093/rheumatology/kex528DOI Listing
May 2018

2017 EULAR recommendations for a core data set to support observational research and clinical care in rheumatoid arthritis.

Authors:
Helga Radner Katerina Chatzidionysiou Elena Nikiphorou Laure Gossec Kimme L Hyrich Condruta Zabalan Yvonne van Eijk-Hustings Paula R Williamson Andra Balanescu Gerd R Burmester Loreto Carmona Maxime Dougados Axel Finckh Glenn Haugeberg Merete Lund Hetland Susan Oliver Duncan Porter Karim Raza Patrick Ryan Maria Jose Santos Annette van der Helm-van Mil Piet van Riel Gabrielle von Krause Jakub Zavada William G Dixon Johan Askling

Ann Rheum Dis 2018 04 4;77(4):476-479. Epub 2018 Jan 4.

Department of Rheumatology, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1136/annrheumdis-2017-212256DOI Listing
April 2018

Long-term persistence of TNF-inhibitor treatment in patients with psoriatic arthritis. Data from the British Society for Rheumatology Biologics Register.

Authors:
Karen Minde Fagerli Lianne Kearsley-Fleet Kath D Watson Jon Packham Bsrbr-Ra Contributors Group Deborah P M Symmons Kimme L Hyrich

RMD Open 2018 7;4(1):e000596. Epub 2018 Jan 7.

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/rmdopen-2017-000596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822639PMC
January 2018

How common is remission in juvenile idiopathic arthritis: A systematic review.

Authors:
Stephanie J W Shoop-Worrall Lianne Kearsley-Fleet Wendy Thomson Suzanne M M Verstappen Kimme L Hyrich

Semin Arthritis Rheum 2017 12 20;47(3):331-337. Epub 2017 May 20.

Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687936PMC
December 2017

How common is clinically inactive disease in a prospective cohort of patients with juvenile idiopathic arthritis? The importance of definition.

Authors:
Stephanie J W Shoop-Worrall Suzanne M M Verstappen Eileen Baildam Alice Chieng Joyce Davidson Helen Foster Yiannis Ioannou Flora McErlane Lucy R Wedderburn Wendy Thomson Kimme L Hyrich

Ann Rheum Dis 2017 Aug 7;76(8):1381-1388. Epub 2017 Apr 7.

Arthritis Research UK Centre for Epidemiology, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-210511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738598PMC
August 2017

Biologics registers in RA: methodological aspects, current role and future applications.

Authors:
Elena Nikiphorou Maya H Buch Kimme L Hyrich

Nat Rev Rheumatol 2017 Aug 1;13(8):503-510. Epub 2017 Jun 1.

National Institute for Health Research (NIHR) Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust; and at the Arthritis Research UK Centre for Epidemiology, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1038/nrrheum.2017.81DOI Listing
August 2017

Mortality in patients with interstitial lung disease treated with rituximab or TNFi as a first biologic.

Authors:
Katie L Druce Kundan Iqbal Kath D Watson Deborah P M Symmons Kimme L Hyrich Clive Kelly

RMD Open 2017 13;3(1):e000473. Epub 2017 Jul 13.

Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/rmdopen-2017-000473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604605PMC
July 2017

Efficacy of biologic therapy across individual juvenile idiopathic arthritis subtypes: A systematic review.

Authors:
Rebecca Davies Danielle Gaynor Kimme L Hyrich Clare E Pain

Semin Arthritis Rheum 2017 04 1;46(5):584-593. Epub 2016 Nov 1.

Department of Paediatric Rheumatology, Alder Hey Children׳s NHS Foundation Trust, Eaton Rd, Liverpool L12 2AP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2016.10.008DOI Listing
April 2017

Efficacy and safety of anti-TNF therapies in psoriatic arthritis: an observational study from the British Society for Rheumatology Biologics Register.

Authors:
Amr A Saad Darren M Ashcroft Kath D Watson Deborah P M Symmons Peter R Noyce Kimme L Hyrich

Rheumatology (Oxford) 2017 04;56(4):672-673

Arthritis Research Campaign (ARC) Epidemiology Unit, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kew454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410980PMC
April 2017

Relationship between exposure to tumour necrosis factor inhibitor therapy and incidence and severity of myocardial infarction in patients with rheumatoid arthritis.

Authors:
Audrey S L Low Deborah P M Symmons Mark Lunt Louise K Mercer Chris P Gale Kath D Watson William G Dixon Kimme L Hyrich

Ann Rheum Dis 2017 04 10;76(4):654-660. Epub 2017 Jan 10.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-209784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530342PMC
April 2017

Pregnancy outcomes in women with rheumatoid arthritis ever treated with rituximab.

Authors:
Diederik De Cock Lucy Birmingham Kath D Watson Lianne Kearsley-Fleet Deborah P Symmons Kimme L Hyrich

Rheumatology (Oxford) 2017 04;56(4):661-663

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Science Centre.

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http://dx.doi.org/10.1093/rheumatology/kew493DOI Listing
April 2017

Risk of lymphoma in patients exposed to antitumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Louise K Mercer James B Galloway Mark Lunt Rebecca Davies Audrey L S Low William G Dixon Kath D Watson Deborah P M Symmons Kimme L Hyrich

Ann Rheum Dis 2017 Mar 8;76(3):497-503. Epub 2016 Aug 8.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-209389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446004PMC
March 2017

Risk of invasive melanoma in patients with rheumatoid arthritis treated with biologics: results from a collaborative project of 11 European biologic registers.

Authors:
Louise K Mercer Johan Askling Pauline Raaschou William G Dixon Lene Dreyer Merete Lund Hetland Anja Strangfeld Angela Zink Xavier Mariette Axel Finckh Helena Canhao Florenzo Iannone Jakub Zavada Jacques Morel Jacques-Eric Gottenberg Kimme L Hyrich Joachim Listing

Ann Rheum Dis 2017 Feb 15;76(2):386-391. Epub 2016 Jun 15.

Epidemiology Unit, German Rheumatism Research Centre, Berlin, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2016-209285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5284347PMC
February 2017

Mortality rates are increased in patients with systemic juvenile idiopathic arthritis.

Authors:
Rebecca Davies Taunton Southwood Lianne Kearsley-Fleet Mark Lunt Eileen Baildam Michael W Beresford Helen E Foster Sharon Douglas Wendy Thomson Diederik De Cock Kimme L Hyrich

Arch Dis Child 2017 02 31;102(2):206-207. Epub 2016 Oct 31.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/archdischild-2016-311571DOI Listing
February 2017

Use and effectiveness of tocilizumab among patients with rheumatoid arthritis: an observational study from the British Society for Rheumatology Biologics Register for rheumatoid arthritis.

Authors:
Mari Kihara Rebecca Davies Lianne Kearsley-Fleet Kath D Watson Mark Lunt Deborah P M Symmons Kimme L Hyrich

Clin Rheumatol 2017 Feb 2;36(2):241-250. Epub 2016 Dec 2.

Arthritis Research UK Centre for Epidemiology, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Room 2.800 Stopford Building, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1007/s10067-016-3485-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290047PMC
February 2017

Response to: 'Does the risk of lymphoma in patients with RA treated with TNF inhibitors differ according to the histological subtype and the type of TNF inhibitor?' by Nocturne et al.

Authors:
Louise K Mercer James B Galloway Mark Lunt Rebecca Davies Audrey Al Low Will G Dixon Kath D Watson Deborah Pm Symmons Kimme L Hyrich

Ann Rheum Dis 2017 02 1;76(2):e4. Epub 2016 Dec 1.

Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-210631DOI Listing
February 2017

High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort.

Authors:
Meghna Jani John D Isaacs Ann W Morgan Anthony G Wilson Darren Plant Kimme L Hyrich Hector Chinoy Anne Barton

Ann Rheum Dis 2017 Jan 31;76(1):208-213. Epub 2016 May 31.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2015-208849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264213PMC
January 2017

Drug-specific risk and characteristics of lupus and vasculitis-like events in patients with rheumatoid arthritis treated with TNFi: results from BSRBR-RA.

Authors:
Meghna Jani William G Dixon Lianne Kersley-Fleet Ian N Bruce Hector Chinoy Anne Barton Mark Lunt Kath Watson Deborah P Symmons Kimme L Hyrich

RMD Open 2017 17;3(1):e000314. Epub 2017 Jan 17.

Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2016-00031
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http://dx.doi.org/10.1136/rmdopen-2016-000314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255894PMC
January 2017

The incidence of cancer in patients with rheumatoid arthritis and a prior malignancy who receive TNF inhibitors or rituximab: results from the British Society for Rheumatology Biologics Register-Rheumatoid Arthritis.

Authors:
Lucía Silva-Fernández Mark Lunt Lianne Kearsley-Fleet Kath D Watson William G Dixon Deborah P M Symmons Kimme L Hyrich

Rheumatology (Oxford) 2016 Nov 22;55(11):2033-2039. Epub 2016 Aug 22.

Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kew314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088627PMC
November 2016

Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels.

Authors:
Meghna Jani John D Isaacs Ann W Morgan Anthony G Wilson Darren Plant Kimme L Hyrich Hector Chinoy Anne Barton

Rheumatology (Oxford) 2016 Nov 25;55(11):2050-2055. Epub 2016 Aug 25.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kew299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088626PMC
November 2016

Melanoma risk in patients with rheumatoid arthritis treated with tumour necrosis factor alpha inhibitors: a systematic review and meta-analysis.

Authors:
Catherine M Olsen Kimme L Hyrich Lani L Knight Adèle C Green

Melanoma Res 2016 10;26(5):517-23

aDepartment of Population Health, QIMR Berghofer Medical Research Institute, Herston, Australia bArthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester cNIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals Foundation Trust, Manchester Academic Health Science Centre dCancer Research UK Manchester Institute and Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1097/CMR.0000000000000284DOI Listing
October 2016

Treatment prescribing patterns in patients with juvenile idiopathic arthritis (JIA): Analysis from the UK Childhood Arthritis Prospective Study (CAPS).

Authors:
Rebecca Davies Roberto Carrasco Helen E Foster Eileen M Baildam S E Alice Chieng Joyce E Davidson Yiannis Ioannou Lucy R Wedderburn Wendy Thomson Kimme L Hyrich

Semin Arthritis Rheum 2016 10 8;46(2):190-195. Epub 2016 Jun 8.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University, Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2016.06.001DOI Listing
October 2016

Patient global assessment in measuring disease activity in rheumatoid arthritis: a review of the literature.

Authors:
Elena Nikiphorou Helga Radner Katerina Chatzidionysiou Carole Desthieux Codruta Zabalan Yvonne van Eijk-Hustings William G Dixon Kimme L Hyrich Johan Askling Laure Gossec

Arthritis Res Ther 2016 10 28;18(1):251. Epub 2016 Oct 28.

Sorbonne Universités, UPMC University Paris 06, Institut Pierre Louis d'Epidémiologie et de Santé Publique, GRC-UPMC 08 (EEMOIS), Paris, France.

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http://dx.doi.org/10.1186/s13075-016-1151-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086038PMC
October 2016

Effectiveness and safety of TNF inhibitors in adults with juvenile idiopathic arthritis.

Authors:
Lianne Kearsley-Fleet Flora McErlane Helen E Foster Mark Lunt Kath D Watson Deborah P M Symmons Kimme L Hyrich

RMD Open 2016 7;2(2):e000273. Epub 2016 Oct 7.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073611PMC
October 2016

Factors associated with choice of biologic among children with Juvenile Idiopathic Arthritis: results from two UK paediatric biologic registers.

Authors:
Lianne Kearsley-Fleet Rebecca Davies Eileen Baildam Michael W Beresford Helen E Foster Taunton R Southwood Wendy Thomson Kimme L Hyrich

Rheumatology (Oxford) 2016 09 4;55(9):1556-65. Epub 2016 Jan 4.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kev429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993954PMC
September 2016

Trends in paediatric rheumatology referral times and disease activity indices over a ten-year period among children and young people with Juvenile Idiopathic Arthritis: results from the childhood arthritis prospective Study.

Authors:
Flora McErlane Helen E Foster Roberto Carrasco Eileen M Baildam S E Alice Chieng Joyce E Davidson Yiannis Ioannou Lucy R Wedderburn Wendy Thomson Kimme L Hyrich

Rheumatology (Oxford) 2016 07 25;55(7):1225-34. Epub 2016 Mar 25.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute for Inflammation and Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kew021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911538PMC
July 2016

Risk of Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis treated with inhibitors of tumour necrosis factor α: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Ellen S Bruce Lianne Kearsley-Fleet Kath D Watson Deborah P M Symmons Kimme L Hyrich

Rheumatology (Oxford) 2016 07 26;55(7):1336-7. Epub 2016 Apr 26.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kew200DOI Listing
July 2016

Association Between Ischemic Stroke and Tumor Necrosis Factor Inhibitor Therapy in Patients With Rheumatoid Arthritis.

Authors:
Audrey S L Low Mark Lunt Louise K Mercer Kath D Watson William G Dixon Deborah P M Symmons Kimme L Hyrich

Arthritis Rheumatol 2016 06;68(6):1337-45

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester and NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1002/art.39582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982051PMC
June 2016

Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis.

Authors:
Darren Plant Amy Webster Nisha Nair James Oliver Samantha L Smith Steven Eyre Kimme L Hyrich Anthony G Wilson Ann W Morgan John D Isaacs Jane Worthington Anne Barton

Arthritis Rheumatol 2016 06 21;68(6):1353-60. Epub 2016 Apr 21.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, and Central Manchester NHS Trust, and Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/art.39590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914881PMC
June 2016

Factors associated with improvement in disease activity following initiation of etanercept in children and young people with Juvenile Idiopathic Arthritis: results from the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study.

Authors:
Lianne Kearsley-Fleet Rebecca Davies Mark Lunt Taunton R Southwood Kimme L Hyrich

Rheumatology (Oxford) 2016 May 31;55(5):840-7. Epub 2015 Dec 31.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kev434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830911PMC
May 2016

Influence of past breast feeding on pattern and severity of presentation of juvenile idiopathic arthritis.

Authors:
Kimme L Hyrich Eileen Baildam Hannah Pickford Alice Chieng Joyce E Davidson Helen Foster Janet Gardner-Medwin Lucy R Wedderburn Wendy Thomson

Arch Dis Child 2016 Apr 14;101(4):348-51. Epub 2015 Sep 14.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK.

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http://dx.doi.org/10.1136/archdischild-2014-308117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819639PMC
April 2016

Psychological factors predict adherence to methotrexate in rheumatoid arthritis; findings from a systematic review of rates, predictors and associations with patient-reported and clinical outcomes.

Authors:
Holly F Hope James Bluett Anne Barton Kimme L Hyrich Lis Cordingley Suzanne M M Verstappen

RMD Open 2016 20;2(1):e000171. Epub 2016 Jan 20.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester , Manchester , UK.

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http://dx.doi.org/10.1136/rmdopen-2015-000171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731843PMC
February 2016

The influence of behavioural and psychological factors on medication adherence over time in rheumatoid arthritis patients: a study in the biologics era.

Authors:
Catharine Morgan John McBeth Lis Cordingley Kath Watson Kimme L Hyrich Deborah P M Symmons Ian N Bruce

Rheumatology (Oxford) 2015 Oct 13;54(10):1780-91. Epub 2015 May 13.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospital NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kev105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571488PMC
October 2015

Medically Significant Infections Are Increased in Patients With Juvenile Idiopathic Arthritis Treated With Etanercept: Results From the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study.

Authors:
Rebecca Davies Taunton R Southwood Lianne Kearsley-Fleet Mark Lunt Kimme L Hyrich

Arthritis Rheumatol 2015 Sep;67(9):2487-94

University of Manchester, Manchester Academic Health Science Centre, and Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

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http://doi.wiley.com/10.1002/art.39197
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http://dx.doi.org/10.1002/art.39197DOI Listing
September 2015

Growth in children and adolescents with juvenile idiopathic arthritis over 2 years of treatment with etanercept: results from the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study.

Authors:
Lianne Kearsley-Fleet Kimme L Hyrich Rebecca Davies Mark Lunt Taunton R Southwood

Rheumatology (Oxford) 2015 Jul 30;54(7):1279-85. Epub 2015 Jan 30.

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Sciences Centre and Institute of Child Health, University of Birmingham and Birmingham Children's Hospital, Birmingham, UK

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/keu489DOI Listing
July 2015

Risk of solid cancer in patients exposed to anti-tumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Authors:
Louise K Mercer Mark Lunt Audrey L S Low William G Dixon Kath D Watson Deborah P M Symmons Kimme L Hyrich

Ann Rheum Dis 2015 Jun 31;74(6):1087-93. Epub 2014 Mar 31.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2013-204851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431340PMC
June 2015

The EULAR Study Group for Registers and Observational Drug Studies: comparability of the patient case mix in the European biologic disease modifying anti-rheumatic drug registers.

Authors:
Lianne Kearsley-Fleet Jakub Závada Merete Lund Hetland Dan C Nordström Kalle J Aaltonen Joachim Listing Angela Zink Tamas Gati Bernadette Rojkovich Florenzo Iannone Elisa Gremese Piet L C M van Riel Martinus A F J van de Laar Elisabeth Lie Tore K Kvien Helena Canhão João E Fonseca Žiga Rotar Estibaliz Loza Loreto Carmona Johan Askling Kari Johansson Axel Finckh William G Dixon Kimme L Hyrich

Rheumatology (Oxford) 2015 Jun 27;54(6):1074-1079. Epub 2014 Nov 27.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK, 2Institute of Rheumatology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 3DANBIO, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, 4Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, 5 Department of Medicine, Helsinki University Central Hospital, 6Faculties of Pharmacy and Medicine, University of Helsinki, Helsinki, Finland, 7German Rheumatism Research Centre, Epidemiology Unit, Berlin, 8German Rheumatism Research Centre, Epidemiology Unit and Charité University Medicine, Berlin, Germany, 9Department of Rheumatology, Semmelweis University, Polyclinic of the Hospitaller Brothers of St John of God, Budapest, Hungary,10Rheumatology Unit, Interdisciplinary Department of Medicine, School of Medicine, University of Bari, Italy, 11Institute of Rheumatology and Affine Sciences, Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, 12Radboud University Medical Center, Rheumatology, Nijmegen, 13Arthritis Centre Twente, Medisch Spectrum Twente & University Twente, Department of Psychology Health and Technology, Enschede, The Netherlands, 14Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 15Rheumatology Research Group, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Portugal, 16Hospital de Santa Maria, Lisbon Academic Medical Centre, Portugal,17Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 18Institute for Musculoskeletal Health, Madrid, Spain,19Karolinska Institutet, Clinical Epidemiology Unit, Department of Medicine Solna, Stockholm, Sweden and 20Division of Rheumatology, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1093/rheumatology/keu446DOI Listing
June 2015

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.

Authors:
Sebastien Viatte Darren Plant Buhm Han Bo Fu Annie Yarwood Wendy Thomson Deborah P M Symmons Jane Worthington Adam Young Kimme L Hyrich Ann W Morgan Anthony G Wilson John D Isaacs Soumya Raychaudhuri Anne Barton

JAMA 2015 Apr;313(16):1645-56

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, England2NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manches.

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http://dx.doi.org/10.1001/jama.2015.3435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928097PMC
April 2015

The association between low socioeconomic status with high physical limitations and low illness self-perception in patients with juvenile idiopathic arthritis: results from the Childhood Arthritis Prospective Study.

Authors:
Suzanne M M Verstappen Joanna Cobb Helen E Foster Bo Fu Eileen Baildam Lucy R Wedderburn Joyce E Davidson John Ioannou Alice Chieng Kimme L Hyrich Wendy Thomson

Arthritis Care Res (Hoboken) 2015 Mar;67(3):382-9

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1002/acr.22466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737227PMC
March 2015

Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.

Authors:
James Bluett Catharine Morgan Layla Thurston Darren Plant Kimme L Hyrich Ann W Morgan Anthony G Wilson John D Isaacs Lis Cordingley Anne Barton

Rheumatology (Oxford) 2015 Mar 10;54(3):494-9. Epub 2014 Sep 10.

Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science, Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, National Institute of Health Research Leeds Musculoskeletal Biomedical Research Unit, Leeds, Academic Unit of Rheumatology, Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University and National Institute of Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne and Institute for Inflammation and Repair, University of Manchester, Manchester, UK. Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science, Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, National Institute of Health Research Leeds Musculoskeletal Biomedical Research Unit, Leeds, Academic Unit of Rheumatology, Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University and National Institute of Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne and Institute for Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/keu358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334684PMC
March 2015

Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.

Authors:
Meghna Jani Hector Chinoy Richard B Warren Christopher E M Griffiths Darren Plant Ann W Morgan Anthony G Wilson Kimme L Hyrich John Isaacs Anne Barton

Lancet 2015 Feb;385 Suppl 1:S48

Centre for Musculoskeletal Research, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, Manchester, UK.

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February 2015

Biologic therapies and pregnancy: the story so far.

Authors:
Kimme L Hyrich Suzanne M M Verstappen

Rheumatology (Oxford) 2014 Aug 17;53(8):1377-85. Epub 2013 Dec 17.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/ket409DOI Listing
August 2014

The risk of gastrointestinal perforations in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the BSRBR-RA.

Authors:
Jakub Závada Mark Lunt Rebecca Davies Audrey Sl Low Louise K Mercer James B Galloway Kath D Watson Deborah P Symmons Kimme L Hyrich

Ann Rheum Dis 2014 Jan 5;73(1):252-5. Epub 2013 May 5.

Arthritis Research UK Epidemiology Unit, The University of Manchester, , Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-203102DOI Listing
January 2014

Validity of a three-variable Juvenile Arthritis Disease Activity Score in children with new-onset juvenile idiopathic arthritis.

Authors:
Flora McErlane Michael W Beresford Eileen M Baildam S E Alice Chieng Joyce E Davidson Helen E Foster Janet Gardner-Medwin Mark Lunt Lucy R Wedderburn Wendy Thomson Kimme L Hyrich

Ann Rheum Dis 2013 Dec 20;72(12):1983-8. Epub 2012 Dec 20.

Arthritis Research UK Epidemiology Unit, University of Manchester, , Manchester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841758PMC
December 2013

Recent developments in disease activity indices and outcome measures for juvenile idiopathic arthritis.

Authors:
Flora McErlane Michael W Beresford Eileen M Baildam Wendy Thomson Kimme L Hyrich

Rheumatology (Oxford) 2013 Nov 28;52(11):1941-51. Epub 2013 Apr 28.

Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/ket150DOI Listing
November 2013

Biologic treatment response among adults with juvenile idiopathic arthritis: results from the British Society for Rheumatology Biologics Register.

Authors:
Flora McErlane Helen E Foster Rebecca Davies Mark Lunt Kath D Watson Deborah P M Symmons Kimme L Hyrich

Rheumatology (Oxford) 2013 Oct 19;52(10):1905-13. Epub 2013 Jul 19.

Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Room 2.800 Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/ket248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775296PMC
October 2013

The incidence of rheumatoid arthritis in the UK: comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register.

Authors:
Jennifer H Humphreys Suzanne M M Verstappen Kimme L Hyrich Jacqueline R Chipping Tarnya Marshall Deborah P M Symmons

Ann Rheum Dis 2013 Aug 3;72(8):1315-20. Epub 2012 Sep 3.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-201960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711368PMC
August 2013

2010 ACR/EULAR classification criteria for rheumatoid arthritis predict increased mortality in patients with early arthritis: results from the Norfolk Arthritis Register.

Authors:
Jennifer H Humphreys Suzanne M M Verstappen Kimme L Hyrich Jacqueline Chipping Deborah P M Symmons

Rheumatology (Oxford) 2013 Jun 5;52(6):1141-2. Epub 2013 Mar 5.

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http://dx.doi.org/10.1093/rheumatology/ket113DOI Listing
June 2013

Influence of anti-TNF patient warning regarding avoidance of high risk foods on rates of listeria and salmonella infections in the UK.

Authors:
Rebecca Davies William G Dixon Kath D Watson Mark Lunt Deborah P M Symmons Kimme L Hyrich

Ann Rheum Dis 2013 Mar 17;72(3):461-2. Epub 2012 Oct 17.

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March 2013

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.

Authors:
Jing Cui Eli A Stahl Saedis Saevarsdottir Corinne Miceli Dorothee Diogo Gosia Trynka Towfique Raj Maša Umiċeviċ Mirkov Helena Canhao Katsunori Ikari Chikashi Terao Yukinori Okada Sara Wedrén Johan Askling Hisashi Yamanaka Shigeki Momohara Atsuo Taniguchi Koichiro Ohmura Fumihiko Matsuda Tsuneyo Mimori Namrata Gupta Manik Kuchroo Ann W Morgan John D Isaacs Anthony G Wilson Kimme L Hyrich Marieke Herenius Marieke E Doorenspleet Paul-Peter Tak J Bart A Crusius Irene E van der Horst-Bruinsma Gert Jan Wolbink Piet L C M van Riel Mart van de Laar Henk-Jan Guchelaar Nancy A Shadick Cornelia F Allaart Tom W J Huizinga Rene E M Toes Robert P Kimberly S Louis Bridges Lindsey A Criswell Larry W Moreland João Eurico Fonseca Niek de Vries Barbara E Stranger Philip L De Jager Soumya Raychaudhuri Michael E Weinblatt Peter K Gregersen Xavier Mariette Anne Barton Leonid Padyukov Marieke J H Coenen Elizabeth W Karlson Robert M Plenge

PLoS Genet 2013 Mar 28;9(3):e1003394. Epub 2013 Mar 28.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610685PMC
March 2013

Risk of skin and soft tissue infections (including shingles) in patients exposed to anti-tumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register.

Authors:
James B Galloway Louise K Mercer Alison Moseley William G Dixon Andrew P Ustianowski Matthew Helbert Kath D Watson Mark Lunt Kimme L Hyrich Deborah Pm Symmons

Ann Rheum Dis 2013 Feb 24;72(2):229-34. Epub 2012 Apr 24.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, Stopford Building, Oxford Road, The University of Manchester, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1136/annrheumdis-2011-201108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595979PMC
February 2013

Anti-TNF therapy in women with rheumatoid arthritis with a history of carcinoma in situ of the cervix.

Authors:
Louise Kate Mercer Audrey Sze Lin Low James B Galloway Kath D Watson Mark Lunt Deborah P M Symmons Kimme L Hyrich

Ann Rheum Dis 2013 Jan 26;72(1):143-4. Epub 2012 Jul 26.

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http://dx.doi.org/10.1136/annrheumdis-2012-201814DOI Listing
January 2013

Risk of cancer in patients receiving non-biologic disease-modifying therapy for rheumatoid arthritis compared with the UK general population.

Authors:
Louise K Mercer Rebecca Davies James B Galloway Audrey Low Mark Lunt William G Dixon Kath D Watson Deborah P M Symmons Kimme L Hyrich

Rheumatology (Oxford) 2013 Jan;52(1):91-8

Arthritis Research UK Epidemiology Unit, Stopford Building, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/kes350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521445PMC
January 2013

Juvenile-onset inflammatory arthritis: a study of adolescents' beliefs about underlying cause.

Authors:
Lis Cordingley Tiffany Vracas Eileen Baildam Alice Chieng Joyce Davidson Helen E Foster Janet Gardner-Medwin Lucy R Wedderburn Wendy Thomson Kimme L Hyrich

Rheumatology (Oxford) 2012 Dec 1;51(12):2239-45. Epub 2012 Sep 1.

School of Community-Based Medicine, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kes216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510429PMC
December 2012

Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.

Authors:
Darren Plant Ibrahim Ibrahim Mark Lunt Stephen Eyre Edward Flynn Kimme L Hyrich Ann W Morgan Anthony G Wilson John D Isaacs Anne Barton

Arthritis Res Ther 2012 Oct 7;14(5):R214. Epub 2012 Oct 7.

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http://dx.doi.org/10.1186/ar4052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580526PMC
October 2012

Rituximab or a second anti-tumor necrosis factor therapy for rheumatoid arthritis patients who have failed their first anti-tumor necrosis factor therapy? Comparative analysis from the British Society for Rheumatology Biologics Register.

Authors:
Moetaza M Soliman Kimme L Hyrich Mark Lunt Kath D Watson Deborah P M Symmons Darren M Ashcroft

Arthritis Care Res (Hoboken) 2012 Aug;64(8):1108-15

University of Manchester, UK.

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http://dx.doi.org/10.1002/acr.21663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492906PMC
August 2012

The influence of anti-TNF therapy upon incidence of keratinocyte skin cancer in patients with rheumatoid arthritis: longitudinal results from the British Society for Rheumatology Biologics Register.

Authors:
Louise K Mercer Adele C Green James B Galloway Rebecca Davies Mark Lunt William G Dixon Kath D Watson Deborah P M Symmons Kimme L Hyrich

Ann Rheum Dis 2012 Jun 12;71(6):869-74. Epub 2012 Jan 12.

Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2011-200622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371225PMC
June 2012

Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort.

Authors:
Darren Plant Rita Prajapati Kimme L Hyrich Ann W Morgan Anthony G Wilson John D Isaacs Anne Barton

Arthritis Rheum 2012 Mar;64(3):665-70

Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/art.33381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427899PMC
March 2012

Abatacept in the long-term treatment of rheumatoid arthritis.

Authors:
Meghna Jani Kimme L Hyrich

Expert Rev Clin Immunol 2012 Mar;8(3):231-4

The University of Manchester Rheumatic Diseases Centre, Salford Royal NHS Foundation Trust, Salford, UK.

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http://dx.doi.org/10.1586/eci.11.98DOI Listing
March 2012

Effectiveness of rituximab in patients with rheumatoid arthritis: observational study from the British Society for Rheumatology Biologics Register.

Authors:
Moetaza M Soliman Kimme L Hyrich Mark Lunt Kath D Watson Deborah P M Symmons Darren M Ashcroft

J Rheumatol 2012 Feb 15;39(2):240-6. Epub 2011 Dec 15.

School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.3899/jrheum.110610DOI Listing
February 2012

Venous thrombotic events are not increased in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register.

Authors:
Rebecca Davies James B Galloway Kath D Watson Mark Lunt Deborah P M Symmons Kimme L Hyrich

Ann Rheum Dis 2011 Oct 22;70(10):1831-4. Epub 2011 Jul 22.

Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.

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http://dx.doi.org/10.1136/ard.2011.153536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168333PMC
October 2011

The risk of serious infections in patients receiving anakinra for rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register.

Authors:
James B Galloway Kimme L Hyrich Louise K Mercer William G Dixon Kath D Watson Mark Lunt Deborah P M Symmons

Rheumatology (Oxford) 2011 Jul 12;50(7):1341-2. Epub 2011 Apr 12.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/ker146DOI Listing
July 2011

Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register.

Authors:
Suzanne M M Verstappen Yvonne King Kath D Watson Deborah P M Symmons Kimme L Hyrich

Ann Rheum Dis 2011 May 28;70(5):823-6. Epub 2011 Feb 28.

Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2010.140822
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http://dx.doi.org/10.1136/ard.2010.140822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070273PMC
May 2011

Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register.

Authors:
Moetaza M Soliman Darren M Ashcroft Kath D Watson Mark Lunt Deborah P M Symmons Kimme L Hyrich

Ann Rheum Dis 2011 Apr 17;70(4):583-9. Epub 2011 Feb 17.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2010.139774
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http://dx.doi.org/10.1136/ard.2010.139774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048625PMC
April 2011

Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci.

Authors:
Darren Plant John Bowes Catherine Potter Kimme L Hyrich Ann W Morgan Anthony G Wilson John D Isaacs Anne Barton

Arthritis Rheum 2011 Mar;63(3):645-53

University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1002/art.30130
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http://dx.doi.org/10.1002/art.30130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084508PMC
March 2011

Drug persistence, effectiveness and safety assessment of anti-TNF therapies in psoriatic arthritis.

Authors:
Amr A Saad Kimme L Hyrich Darren M Ashcroft

Expert Opin Drug Saf 2011 Mar 6;10(2):219-26. Epub 2011 Jan 6.

Egyptian Pharmacovigilance Centre, Central Administration for Pharmaceutical Affairs, Ministry of Health, Cairo, PO Box 11451, Egypt.

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http://dx.doi.org/10.1517/14740338.2010.516250DOI Listing
March 2011

Agreement between proxy and adolescent assessment of disability, pain, and well-being in juvenile idiopathic arthritis.

Authors:
Sham D Lal Janet McDonagh Eileen Baildam Lucy R Wedderburn Janet Gardner-Medwin Helen E Foster Alice Chieng Joyce Davidson Navid Adib Wendy Thomson Kimme L Hyrich

J Pediatr 2011 Feb;158(2):307-12

Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00223476100066
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http://dx.doi.org/10.1016/j.jpeds.2010.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202630PMC
February 2011

Changes in disease characteristics and response rates among patients in the United Kingdom starting anti-tumour necrosis factor therapy for rheumatoid arthritis between 2001 and 2008.

Authors:
Kimme L Hyrich Kath D Watson Mark Lunt Deborah P M Symmons

Rheumatology (Oxford) 2011 Jan 29;50(1):117-23. Epub 2010 Jul 29.

Arthritis Research UK Epidemiology Unit, Stopford Building, University of Manchester, Manchester Academic Health Sciences Centre, Oxford Road, Manchester M13 9PT, UK.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/keq209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999956PMC
January 2011

Anti-TNF therapy is associated with an increased risk of serious infections in patients with rheumatoid arthritis especially in the first 6 months of treatment: updated results from the British Society for Rheumatology Biologics Register with special emphasis on risks in the elderly.

Authors:
James B Galloway Kimme L Hyrich Louise K Mercer William G Dixon Bo Fu Andrew P Ustianowski Kath D Watson Mark Lunt Deborah P M Symmons

Rheumatology (Oxford) 2011 Jan 31;50(1):124-31. Epub 2010 Jul 31.

Arthritis Research UK Epidemiology Unit, The University of Manchester, Department of Infectious Diseases, North Manchester General Hospital, Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/keq242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105607PMC
January 2011

Duration of etanercept treatment and reasons for discontinuation in a cohort of juvenile idiopathic arthritis patients.

Authors:
Taunton R Southwood Helen E Foster Joyce E Davidson Kimme L Hyrich Catherine B Cotter Lucy R Wedderburn Richard G Hull Helen E Venning Joy K Rahman Carole L Cummins

Rheumatology (Oxford) 2011 Jan 3;50(1):189-95. Epub 2010 Nov 3.

Department of Paediatric Rheumatology, Institute of Child Health, 4th Floor Laboratories Block, Birmingham Children's Hospital-NHS Foundation Trust, University of Birmingham, Whittall Street, Birmingham, B4 6NH, UK.

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http://dx.doi.org/10.1093/rheumatology/keq308DOI Listing
January 2011

No evidence of association between anti-tumor necrosis factor treatment and mortality in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register.

Authors:
Mark Lunt Kath D Watson William G Dixon Deborah P M Symmons Kimme L Hyrich

Arthritis Rheum 2010 Nov;62(11):3145-53

Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1002/art.27660
Publisher Site
http://dx.doi.org/10.1002/art.27660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061010PMC
November 2010

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.

Authors:
Catherine Potter Heather J Cordell Anne Barton Ann K Daly Kimme L Hyrich Derek A Mann Ann W Morgan Anthony G Wilson John D Isaacs

Ann Rheum Dis 2010 Jul 6;69(7):1315-20. Epub 2010 May 6.

Musculoskeletal Research Group, Institute of Cellular Medicine, University of Newcastle, 4th Floor Catherine Cookson Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1136/ard.2009.117309DOI Listing
July 2010

Methotrexate for rheumatoid arthritis: a guide from Canada.

Authors:
Suzanne M M Verstappen Kimme L Hyrich

J Rheumatol 2010 Jul;37(7):1374-6

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http://dx.doi.org/10.3899/jrheum.100187DOI Listing
July 2010