Kimme L Hyrich

Kimme L Hyrich

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Kimme L Hyrich

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Cervical screening uptake and rates of cervical dysplasia in the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Rheumatology (Oxford) 2020 Mar;59(3):559-567

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kez277DOI Listing
March 2020

Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity.

PLoS One 2019 20;14(5):e0215999. Epub 2019 May 20.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215999PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527224PMC
January 2020

The predictors of and reasons for non-adherence in an observational cohort of patients with rheumatoid arthritis commencing methotrexate.

Rheumatology (Oxford) 2020 Jan;59(1):213-223

NIHR Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kez274DOI Listing
January 2020

What can rheumatology expect from real-world data?

Rheumatology (Oxford) 2020 Jan;59(1):12-13

German Rheumatism Research Centre, Epidemiology Unit, Berlin, Germany.

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http://dx.doi.org/10.1093/rheumatology/kez366DOI Listing
January 2020

Real world data in rheumatology.

Authors:
Kimme L Hyrich

Semin Arthritis Rheum 2019 12;49(3S):S22-S24

Centre for Epidemiology Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester M13 9PT, UK; National Institute of Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2019.09.021DOI Listing
December 2019

Long-term outcomes of patients who rate symptoms of rheumatoid arthritis as 'satisfactory'.

Rheumatology (Oxford) 2019 Nov 15. Epub 2019 Nov 15.

Centre for Epidemiology Versus Arthritis, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre.

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http://dx.doi.org/10.1093/rheumatology/kez497DOI Listing
November 2019

Predicting disease outcomes in juvenile idiopathic arthritis: challenges, evidence, and new directions.

Lancet Child Adolesc Health 2019 Oct 19;3(10):725-733. Epub 2019 Jul 19.

UCL Great Ormond Street Institute of Child Health, University College London, London, UK; Centre for Adolescent Rheumatology Versus Arthritis at University College London, University College London Hospital, and Great Ormond Street Hospital, University College London, London, UK; National Institute of Health Research Biomedical Research Centre at Great Ormond Street Hospital, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(19)30188-9DOI Listing
October 2019

Differential DNA methylation correlates with response to methotrexate in rheumatoid arthritis.

Rheumatology (Oxford) 2019 Oct 10. Epub 2019 Oct 10.

University College Dublin School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1093/rheumatology/kez411DOI Listing
October 2019

The risk of uveitis in patients with JIA receiving etanercept: the challenges of analysing real-world data.

Rheumatology (Oxford) 2019 Oct 12. Epub 2019 Oct 12.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, The University of Manchester, Manchester Academic Health Science Centre, Manchester.

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http://dx.doi.org/10.1093/rheumatology/kez449DOI Listing
October 2019

A UK study: vocational experiences of young adults with juvenile idiopathic arthritis.

Pediatr Rheumatol Online J 2019 08 6;17(1):54. Epub 2019 Aug 6.

Centre for Epidemiology Versus Arthritis, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1186/s12969-019-0357-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683541PMC
August 2019

Predicting Remission Remains a Challenge in Patients with Juvenile Idiopathic Arthritis.

J Rheumatol 2019 Jun;46(6):552-554

Arthritis Research UK Centre for Epidemiology, The University of Manchester, and the UK National Institute for Health Research Manchester Biomedical Research Centre, Manchester University Hospitals, National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.3899/jrheum.181245DOI Listing
June 2019

Comparing Proxy, Adolescent and Adult Assessments of Functional Ability in Adolescents with Juvenile Idiopathic Arthritis.

Arthritis Care Res (Hoboken) 2019 Mar 15. Epub 2019 Mar 15.

NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1002/acr.23877DOI Listing
March 2019

Short-term outcomes in patients with systemic juvenile idiopathic arthritis treated with either tocilizumab or anakinra.

Rheumatology (Oxford) 2019 01;58(1):94-102

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/key262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293481PMC
January 2019

Biologic refractory disease in rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Ann Rheum Dis 2018 10 6;77(10):1405-1412. Epub 2018 Jul 6.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2018-213378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161665PMC
October 2018

Long-Term Outcomes Following Achievement of Clinically Inactive Disease in Juvenile Idiopathic Arthritis: The Importance of Definition.

Arthritis Rheumatol 2018 09 22;70(9):1519-1529. Epub 2018 Jul 22.

The University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://doi.wiley.com/10.1002/art.40519
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http://dx.doi.org/10.1002/art.40519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175118PMC
September 2018

Growth patterns in early juvenile idiopathic arthritis: Results from the Childhood Arthritis Prospective Study (CAPS).

Semin Arthritis Rheum 2018 08 7;48(1):53-60. Epub 2017 Nov 7.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Division of Musculoskeletal & Dermatological Sciences. Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089842PMC
August 2018

Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS).

Arthritis Res Ther 2018 07 13;20(1):147. Epub 2018 Jul 13.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1186/s13075-018-1645-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044018PMC
July 2018

Long-term persistence with rituximab in patients with rheumatoid arthritis.

Rheumatology (Oxford) 2018 06;57(6):1089-1096

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/key036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965076PMC
June 2018

Patterns of pain over time among children with juvenile idiopathic arthritis.

Arch Dis Child 2018 05 25;103(5):437-443. Epub 2017 Nov 25.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1136/archdischild-2017-313337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916104PMC
May 2018

How common is remission in juvenile idiopathic arthritis: A systematic review.

Semin Arthritis Rheum 2017 12 20;47(3):331-337. Epub 2017 May 20.

Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687936PMC
December 2017

How common is clinically inactive disease in a prospective cohort of patients with juvenile idiopathic arthritis? The importance of definition.

Ann Rheum Dis 2017 Aug 7;76(8):1381-1388. Epub 2017 Apr 7.

Arthritis Research UK Centre for Epidemiology, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-210511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738598PMC
August 2017

Biologics registers in RA: methodological aspects, current role and future applications.

Nat Rev Rheumatol 2017 Aug 1;13(8):503-510. Epub 2017 Jun 1.

National Institute for Health Research (NIHR) Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Central Manchester University Hospitals NHS Foundation Trust; and at the Arthritis Research UK Centre for Epidemiology, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1038/nrrheum.2017.81DOI Listing
August 2017

Mortality in patients with interstitial lung disease treated with rituximab or TNFi as a first biologic.

RMD Open 2017 13;3(1):e000473. Epub 2017 Jul 13.

Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/rmdopen-2017-000473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604605PMC
July 2017

Efficacy of biologic therapy across individual juvenile idiopathic arthritis subtypes: A systematic review.

Semin Arthritis Rheum 2017 04 1;46(5):584-593. Epub 2016 Nov 1.

Department of Paediatric Rheumatology, Alder Hey Children׳s NHS Foundation Trust, Eaton Rd, Liverpool L12 2AP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2016.10.008DOI Listing
April 2017

Relationship between exposure to tumour necrosis factor inhibitor therapy and incidence and severity of myocardial infarction in patients with rheumatoid arthritis.

Ann Rheum Dis 2017 04 10;76(4):654-660. Epub 2017 Jan 10.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-209784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530342PMC
April 2017

Pregnancy outcomes in women with rheumatoid arthritis ever treated with rituximab.

Rheumatology (Oxford) 2017 04;56(4):661-663

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Science Centre.

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http://dx.doi.org/10.1093/rheumatology/kew493DOI Listing
April 2017

Risk of lymphoma in patients exposed to antitumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Ann Rheum Dis 2017 Mar 8;76(3):497-503. Epub 2016 Aug 8.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-209389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446004PMC
March 2017

Mortality rates are increased in patients with systemic juvenile idiopathic arthritis.

Arch Dis Child 2017 02 31;102(2):206-207. Epub 2016 Oct 31.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/archdischild-2016-311571DOI Listing
February 2017

Use and effectiveness of tocilizumab among patients with rheumatoid arthritis: an observational study from the British Society for Rheumatology Biologics Register for rheumatoid arthritis.

Clin Rheumatol 2017 Feb 2;36(2):241-250. Epub 2016 Dec 2.

Arthritis Research UK Centre for Epidemiology, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Room 2.800 Stopford Building, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1007/s10067-016-3485-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290047PMC
February 2017

High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort.

Ann Rheum Dis 2017 Jan 31;76(1):208-213. Epub 2016 May 31.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2015-208849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264213PMC
January 2017

Drug-specific risk and characteristics of lupus and vasculitis-like events in patients with rheumatoid arthritis treated with TNFi: results from BSRBR-RA.

RMD Open 2017 17;3(1):e000314. Epub 2017 Jan 17.

Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2016-00031
Publisher Site
http://dx.doi.org/10.1136/rmdopen-2016-000314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255894PMC
January 2017

Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels.

Rheumatology (Oxford) 2016 Nov 25;55(11):2050-2055. Epub 2016 Aug 25.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kew299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088626PMC
November 2016

Melanoma risk in patients with rheumatoid arthritis treated with tumour necrosis factor alpha inhibitors: a systematic review and meta-analysis.

Melanoma Res 2016 10;26(5):517-23

aDepartment of Population Health, QIMR Berghofer Medical Research Institute, Herston, Australia bArthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester cNIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals Foundation Trust, Manchester Academic Health Science Centre dCancer Research UK Manchester Institute and Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1097/CMR.0000000000000284DOI Listing
October 2016

Treatment prescribing patterns in patients with juvenile idiopathic arthritis (JIA): Analysis from the UK Childhood Arthritis Prospective Study (CAPS).

Semin Arthritis Rheum 2016 10 8;46(2):190-195. Epub 2016 Jun 8.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University, Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052142PMC
http://dx.doi.org/10.1016/j.semarthrit.2016.06.001DOI Listing
October 2016

Patient global assessment in measuring disease activity in rheumatoid arthritis: a review of the literature.

Arthritis Res Ther 2016 10 28;18(1):251. Epub 2016 Oct 28.

Sorbonne Universités, UPMC University Paris 06, Institut Pierre Louis d'Epidémiologie et de Santé Publique, GRC-UPMC 08 (EEMOIS), Paris, France.

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http://dx.doi.org/10.1186/s13075-016-1151-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086038PMC
October 2016

Effectiveness and safety of TNF inhibitors in adults with juvenile idiopathic arthritis.

RMD Open 2016 7;2(2):e000273. Epub 2016 Oct 7.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK.

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http://dx.doi.org/10.1136/rmdopen-2016-000273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073611PMC
October 2016

Factors associated with choice of biologic among children with Juvenile Idiopathic Arthritis: results from two UK paediatric biologic registers.

Rheumatology (Oxford) 2016 09 4;55(9):1556-65. Epub 2016 Jan 4.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK

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http://rheumatology.oxfordjournals.org/content/early/2016/03
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http://www.rheumatology.oxfordjournals.org/lookup/doi/10.109
Publisher Site
http://dx.doi.org/10.1093/rheumatology/kev429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993954PMC
September 2016

Trends in paediatric rheumatology referral times and disease activity indices over a ten-year period among children and young people with Juvenile Idiopathic Arthritis: results from the childhood arthritis prospective Study.

Rheumatology (Oxford) 2016 07 25;55(7):1225-34. Epub 2016 Mar 25.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute for Inflammation and Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kew021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911538PMC
July 2016

Risk of Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis treated with inhibitors of tumour necrosis factor α: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Rheumatology (Oxford) 2016 07 26;55(7):1336-7. Epub 2016 Apr 26.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kew200DOI Listing
July 2016

Association Between Ischemic Stroke and Tumor Necrosis Factor Inhibitor Therapy in Patients With Rheumatoid Arthritis.

Arthritis Rheumatol 2016 06;68(6):1337-45

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester and NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1002/art.39582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982051PMC
June 2016

Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis.

Arthritis Rheumatol 2016 06 21;68(6):1353-60. Epub 2016 Apr 21.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, and Central Manchester NHS Trust, and Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/art.39590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914881PMC
June 2016

Factors associated with improvement in disease activity following initiation of etanercept in children and young people with Juvenile Idiopathic Arthritis: results from the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study.

Rheumatology (Oxford) 2016 May 31;55(5):840-7. Epub 2015 Dec 31.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, The University of Manchester, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester Partnership, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kev434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830911PMC
May 2016

Influence of past breast feeding on pattern and severity of presentation of juvenile idiopathic arthritis.

Arch Dis Child 2016 Apr 14;101(4):348-51. Epub 2015 Sep 14.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK.

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http://dx.doi.org/10.1136/archdischild-2014-308117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819639PMC
April 2016

Psychological factors predict adherence to methotrexate in rheumatoid arthritis; findings from a systematic review of rates, predictors and associations with patient-reported and clinical outcomes.

RMD Open 2016 20;2(1):e000171. Epub 2016 Jan 20.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester , Manchester , UK.

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http://dx.doi.org/10.1136/rmdopen-2015-000171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731843PMC
February 2016

The influence of behavioural and psychological factors on medication adherence over time in rheumatoid arthritis patients: a study in the biologics era.

Rheumatology (Oxford) 2015 Oct 13;54(10):1780-91. Epub 2015 May 13.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospital NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kev105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571488PMC
October 2015

Growth in children and adolescents with juvenile idiopathic arthritis over 2 years of treatment with etanercept: results from the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study.

Rheumatology (Oxford) 2015 Jul 30;54(7):1279-85. Epub 2015 Jan 30.

Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester Academic Health Sciences Centre and Institute of Child Health, University of Birmingham and Birmingham Children's Hospital, Birmingham, UK

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
Publisher Site
http://dx.doi.org/10.1093/rheumatology/keu489DOI Listing
July 2015

Risk of solid cancer in patients exposed to anti-tumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis.

Ann Rheum Dis 2015 Jun 31;74(6):1087-93. Epub 2014 Mar 31.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2013-204851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431340PMC
June 2015

The EULAR Study Group for Registers and Observational Drug Studies: comparability of the patient case mix in the European biologic disease modifying anti-rheumatic drug registers.

Rheumatology (Oxford) 2015 Jun 27;54(6):1074-1079. Epub 2014 Nov 27.

Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK, 2Institute of Rheumatology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 3DANBIO, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, 4Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, 5 Department of Medicine, Helsinki University Central Hospital, 6Faculties of Pharmacy and Medicine, University of Helsinki, Helsinki, Finland, 7German Rheumatism Research Centre, Epidemiology Unit, Berlin, 8German Rheumatism Research Centre, Epidemiology Unit and Charité University Medicine, Berlin, Germany, 9Department of Rheumatology, Semmelweis University, Polyclinic of the Hospitaller Brothers of St John of God, Budapest, Hungary,10Rheumatology Unit, Interdisciplinary Department of Medicine, School of Medicine, University of Bari, Italy, 11Institute of Rheumatology and Affine Sciences, Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, 12Radboud University Medical Center, Rheumatology, Nijmegen, 13Arthritis Centre Twente, Medisch Spectrum Twente & University Twente, Department of Psychology Health and Technology, Enschede, The Netherlands, 14Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 15Rheumatology Research Group, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Portugal, 16Hospital de Santa Maria, Lisbon Academic Medical Centre, Portugal,17Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 18Institute for Musculoskeletal Health, Madrid, Spain,19Karolinska Institutet, Clinical Epidemiology Unit, Department of Medicine Solna, Stockholm, Sweden and 20Division of Rheumatology, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1093/rheumatology/keu446DOI Listing
June 2015

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.

JAMA 2015 Apr;313(16):1645-56

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, England2NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manches.

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http://dx.doi.org/10.1001/jama.2015.3435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928097PMC
April 2015

The association between low socioeconomic status with high physical limitations and low illness self-perception in patients with juvenile idiopathic arthritis: results from the Childhood Arthritis Prospective Study.

Arthritis Care Res (Hoboken) 2015 Mar;67(3):382-9

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1002/acr.22466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737227PMC
March 2015

Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.

Rheumatology (Oxford) 2015 Mar 10;54(3):494-9. Epub 2014 Sep 10.

Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science, Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, National Institute of Health Research Leeds Musculoskeletal Biomedical Research Unit, Leeds, Academic Unit of Rheumatology, Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University and National Institute of Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne and Institute for Inflammation and Repair, University of Manchester, Manchester, UK. Arthritis Research UK Centre for Genetics and Genomics, University of Manchester, National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science, Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, National Institute of Health Research Leeds Musculoskeletal Biomedical Research Unit, Leeds, Academic Unit of Rheumatology, Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University and National Institute of Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne and Institute for Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/keu358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334684PMC
March 2015

Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.

Lancet 2015 Feb;385 Suppl 1:S48

Centre for Musculoskeletal Research, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, Manchester, UK.

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February 2015

Biologic therapies and pregnancy: the story so far.

Rheumatology (Oxford) 2014 Aug 17;53(8):1377-85. Epub 2013 Dec 17.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/ket409DOI Listing
August 2014

The risk of gastrointestinal perforations in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the BSRBR-RA.

Ann Rheum Dis 2014 Jan 5;73(1):252-5. Epub 2013 May 5.

Arthritis Research UK Epidemiology Unit, The University of Manchester, , Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-203102DOI Listing
January 2014

Recent developments in disease activity indices and outcome measures for juvenile idiopathic arthritis.

Rheumatology (Oxford) 2013 Nov 28;52(11):1941-51. Epub 2013 Apr 28.

Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/ket150DOI Listing
November 2013

Biologic treatment response among adults with juvenile idiopathic arthritis: results from the British Society for Rheumatology Biologics Register.

Rheumatology (Oxford) 2013 Oct 19;52(10):1905-13. Epub 2013 Jul 19.

Arthritis Research UK Epidemiology Unit, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Room 2.800 Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/ket248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775296PMC
October 2013

Risk of skin and soft tissue infections (including shingles) in patients exposed to anti-tumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register.

Ann Rheum Dis 2013 Feb 24;72(2):229-34. Epub 2012 Apr 24.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, Stopford Building, Oxford Road, The University of Manchester, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1136/annrheumdis-2011-201108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595979PMC
February 2013

Risk of cancer in patients receiving non-biologic disease-modifying therapy for rheumatoid arthritis compared with the UK general population.

Rheumatology (Oxford) 2013 Jan;52(1):91-8

Arthritis Research UK Epidemiology Unit, Stopford Building, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/kes350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521445PMC
January 2013

Abatacept in the long-term treatment of rheumatoid arthritis.

Expert Rev Clin Immunol 2012 Mar;8(3):231-4

The University of Manchester Rheumatic Diseases Centre, Salford Royal NHS Foundation Trust, Salford, UK.

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http://dx.doi.org/10.1586/eci.11.98DOI Listing
March 2012

Effectiveness of rituximab in patients with rheumatoid arthritis: observational study from the British Society for Rheumatology Biologics Register.

J Rheumatol 2012 Feb 15;39(2):240-6. Epub 2011 Dec 15.

School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.3899/jrheum.110610DOI Listing
February 2012

Venous thrombotic events are not increased in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register.

Ann Rheum Dis 2011 Oct 22;70(10):1831-4. Epub 2011 Jul 22.

Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.

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http://dx.doi.org/10.1136/ard.2011.153536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168333PMC
October 2011

Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register.

Ann Rheum Dis 2011 May 28;70(5):823-6. Epub 2011 Feb 28.

Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070273PMC
May 2011

Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register.

Ann Rheum Dis 2011 Apr 17;70(4):583-9. Epub 2011 Feb 17.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2010.139774
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048625PMC
April 2011

Drug persistence, effectiveness and safety assessment of anti-TNF therapies in psoriatic arthritis.

Expert Opin Drug Saf 2011 Mar 6;10(2):219-26. Epub 2011 Jan 6.

Egyptian Pharmacovigilance Centre, Central Administration for Pharmaceutical Affairs, Ministry of Health, Cairo, PO Box 11451, Egypt.

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http://dx.doi.org/10.1517/14740338.2010.516250DOI Listing
March 2011

Changes in disease characteristics and response rates among patients in the United Kingdom starting anti-tumour necrosis factor therapy for rheumatoid arthritis between 2001 and 2008.

Rheumatology (Oxford) 2011 Jan 29;50(1):117-23. Epub 2010 Jul 29.

Arthritis Research UK Epidemiology Unit, Stopford Building, University of Manchester, Manchester Academic Health Sciences Centre, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/keq209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999956PMC
January 2011

Duration of etanercept treatment and reasons for discontinuation in a cohort of juvenile idiopathic arthritis patients.

Rheumatology (Oxford) 2011 Jan 3;50(1):189-95. Epub 2010 Nov 3.

Department of Paediatric Rheumatology, Institute of Child Health, 4th Floor Laboratories Block, Birmingham Children's Hospital-NHS Foundation Trust, University of Birmingham, Whittall Street, Birmingham, B4 6NH, UK.

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http://dx.doi.org/10.1093/rheumatology/keq308DOI Listing
January 2011

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.

Ann Rheum Dis 2010 Jul 6;69(7):1315-20. Epub 2010 May 6.

Musculoskeletal Research Group, Institute of Cellular Medicine, University of Newcastle, 4th Floor Catherine Cookson Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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http://dx.doi.org/10.1136/ard.2009.117309DOI Listing
July 2010

Methotrexate for rheumatoid arthritis: a guide from Canada.

J Rheumatol 2010 Jul;37(7):1374-6

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http://dx.doi.org/10.3899/jrheum.100187DOI Listing
July 2010