Kimberly D Siegmund

Kimberly D Siegmund

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Kimberly D Siegmund

Kimberly D Siegmund

Publications by authors named "Kimberly D Siegmund"

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Mutational signatures in colon cancer.

BMC Res Notes 2019 Dec 3;12(1):788. Epub 2019 Dec 3.

Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90032, USA.

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http://dx.doi.org/10.1186/s13104-019-4820-0DOI Listing
December 2019

HiLDA: a statistical approach to investigate differences in mutational signatures.

PeerJ 2019 28;7:e7557. Epub 2019 Aug 28.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America.

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http://dx.doi.org/10.7717/peerj.7557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717498PMC
August 2019

Deregulation of Biologically Significant Genes and Associated Molecular Pathways in the Oral Epithelium of Electronic Cigarette Users.

Int J Mol Sci 2019 Feb 10;20(3). Epub 2019 Feb 10.

Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, M/C 9603, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.3390/ijms20030738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386888PMC
February 2019

Association between promoter methylation and lung function growth during adolescence.

Epigenetics 2018 19;13(10-11):1027-1038. Epub 2018 Oct 19.

a Department of Preventive Medicine , USC Keck School of Medicine , Los Angeles , CA , USA.

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http://dx.doi.org/10.1080/15592294.2018.1529517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342069PMC
October 2018

Data integration by multi-tuning parameter elastic net regression.

BMC Bioinformatics 2018 Oct 10;19(1):369. Epub 2018 Oct 10.

Department of Preventive Medicine, USC Keck School of Medicine, 2001 N Soto Street, Los Angeles, CA, 90089, USA.

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http://dx.doi.org/10.1186/s12859-018-2401-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180486PMC
October 2018

Epigenetic regulation of and risk of childhood asthma symptoms.

Clin Epigenetics 2017 7;9:121. Epub 2017 Nov 7.

Department of Preventive Medicine, USC Keck School of Medicine, 2001 N. Soto Street, Los Angeles, CA 90032 USA.

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https://clinicalepigeneticsjournal.biomedcentral.com/article
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http://dx.doi.org/10.1186/s13148-017-0421-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688797PMC
July 2018

Comprehensive meta-analysis reveals association between multiple imprinting disorders and conception by assisted reproductive technology.

J Assist Reprod Genet 2018 Jun 25;35(6):943-952. Epub 2018 Apr 25.

Department of Preventive Medicine, Keck School of Medicine at USC, 1441 Eastlake Avenue, MC-9175, Los Angeles, CA, 90089-9175, USA.

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http://dx.doi.org/10.1007/s10815-018-1173-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030010PMC
June 2018

Spatial mutation patterns as markers of early colorectal tumor cell mobility.

Proc Natl Acad Sci U S A 2018 05 14;115(22):5774-5779. Epub 2018 May 14.

Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033;

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http://dx.doi.org/10.1073/pnas.1716552115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984490PMC
May 2018

Improving needle biopsy accuracy in small renal mass using tumor-specific DNA methylation markers.

Oncotarget 2017 Jan;8(3):5439-5448

Department of Preventive Medicine, Norris Comprehensive Cancer Center, USC Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.18632/oncotarget.12276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354921PMC
January 2017

An evaluation of processing methods for HumanMethylation450 BeadChip data.

BMC Genomics 2016 06 22;17:469. Epub 2016 Jun 22.

Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, Los Angeles, USA.

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http://dx.doi.org/10.1186/s12864-016-2819-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918139PMC
June 2016

Particulate matter, the newborn methylome, and cardio-respiratory health outcomes in childhood.

Environ Epigenet 2016 Apr 12;2(2):dvw005. Epub 2016 Jun 12.

University of Southern California, Dept of Preventive Medicine, 2001 N Soto St, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1093/eep/dvw005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804519PMC
April 2016

Distinct, genome-wide, gene-specific selectivity patterns of four glucocorticoid receptor coregulators.

Nucl Recept Signal 2014 4;12:e002. Epub 2014 Nov 4.

Department of Biochemistry and Molecular Biology (D-Y W, C-Y O, RC, MRS), Department of Preventive Medicine (KDS), USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089.

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http://dx.doi.org/10.1621/nrs.12002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242289PMC
June 2015

Identifying differential transcription factor binding in ChIP-seq.

Front Genet 2015 29;6:169. Epub 2015 Apr 29.

Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, University of Southern California Los Angeles, CA, USA.

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http://dx.doi.org/10.3389/fgene.2015.00169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413818PMC
May 2015

Transcriptomic Profiling of Primary Alveolar Epithelial Cell Differentiation in Human and Rat.

Genom Data 2014 Dec;2:105-109

Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America ; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America ; Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1016/j.gdata.2014.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203668PMC
December 2014

Ancestral inference in tumors: how much can we know?

J Theor Biol 2014 Oct 5;359:136-45. Epub 2014 Jun 5.

Department of Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00225193140030
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http://dx.doi.org/10.1016/j.jtbi.2014.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138290PMC
October 2014

Non-specific filtering of beta-distributed data.

BMC Bioinformatics 2014 Jun 19;15:199. Epub 2014 Jun 19.

Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, 2001 N Soto Street, Suite 202W, Los Angeles 90089-9239 California, USA.

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http://dx.doi.org/10.1186/1471-2105-15-199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230495PMC
June 2014

A panel of three markers hyper- and hypomethylated in urine sediments accurately predicts bladder cancer recurrence.

Clin Cancer Res 2014 Apr;20(7):1978-89

Authors' Affiliations: Departments of Urology and Preventive Medicine; Program in Genetic, Molecular, and Cellular Biology, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles; and Department of Urology, School of Medicine, University of Stanford, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2637DOI Listing
April 2014

Recommendations for the design and analysis of epigenome-wide association studies.

Nat Methods 2013 Oct;10(10):949-55

1] Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://search.proquest.com/openview/9eb6080ebfd0ecdda97a57d6
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http://dx.doi.org/10.1038/nmeth.2632DOI Listing
October 2013

Low-level processing of Illumina Infinium DNA Methylation BeadArrays.

Nucleic Acids Res 2013 Apr 9;41(7):e90. Epub 2013 Mar 9.

Department of Preventive Medicine, USC Keck School of Medicine of USC, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1093/nar/gkt090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627582PMC
April 2013

G9a functions as a molecular scaffold for assembly of transcriptional coactivators on a subset of glucocorticoid receptor target genes.

Proc Natl Acad Sci U S A 2012 Nov 14;109(48):19673-8. Epub 2012 Nov 14.

Department of Biochemistry and Molecular Biology, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1211803109
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http://dx.doi.org/10.1073/pnas.1211803109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511704PMC
November 2012

Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.

Hum Genet 2012 Oct 28;131(10):1565-89. Epub 2012 Jun 28.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USC Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1007/s00439-012-1189-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432200PMC
October 2012

Particulate matter, DNA methylation in nitric oxide synthase, and childhood respiratory disease.

Environ Health Perspect 2012 Sep 16;120(9):1320-6. Epub 2012 May 16.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1289/ehp.1104439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440108PMC
September 2012

Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression.

Genome Res 2012 Jul 21;22(7):1197-211. Epub 2012 May 21.

Department of Surgery, Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089-9176, USA.

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http://dx.doi.org/10.1101/gr.132662.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396362PMC
July 2012

Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.

Int J Cancer 2012 Apr 8;130(8):1898-907. Epub 2011 Aug 8.

Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, CA, USA.

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http://dx.doi.org/10.1002/ijc.26199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883510PMC
April 2012

Selective roles for cAMP response element-binding protein binding protein and p300 protein as coregulators for androgen-regulated gene expression in advanced prostate cancer cells.

J Biol Chem 2012 Feb 15;287(6):4000-13. Epub 2011 Dec 15.

Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089-9176, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111.300194
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http://dx.doi.org/10.1074/jbc.M111.300194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281703PMC
February 2012

High DNA methylation pattern intratumoral diversity implies weak selection in many human colorectal cancers.

PLoS One 2011 28;6(6):e21657. Epub 2011 Jun 28.

Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021657PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125304PMC
December 2011

DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.

PLoS One 2011 23;6(6):e21443. Epub 2011 Jun 23.

Department of Surgery, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021443PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121768PMC
November 2011

Modeling measurement error in tumor characterization studies.

BMC Bioinformatics 2011 Jul 13;12:284. Epub 2011 Jul 13.

Department of Preventive Medicine, USC Keck School of Medicine, Los Angeles, California 90089-9176, USA.

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http://dx.doi.org/10.1186/1471-2105-12-284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213130PMC
July 2011

Statistical approaches for the analysis of DNA methylation microarray data.

Hum Genet 2011 Jun 26;129(6):585-95. Epub 2011 Apr 26.

Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1007/s00439-011-0993-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166559PMC
June 2011

Human and great ape red blood cells differ in plasmalogen levels and composition.

Lipids Health Dis 2011 Jun 17;10:101. Epub 2011 Jun 17.

Hugo W. Moser Research Institute at Kennedy Krieger, and Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1186/1476-511X-10-101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129581PMC
June 2011

The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history.

Gastroenterology 2011 Jan 19;140(1):73-81. Epub 2010 Aug 19.

Herbert Irving Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Columbia University Medical Center, New York, New York 10032, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125673PMC
January 2011

Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue.

Cancer Res 2010 Oct 14;70(20):8169-78. Epub 2010 Sep 14.

Department of Urology, USC Epigenome Center, and Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Keck School of Medicine, Los Angeles, CA 90089, USA.

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http://cancerres.aacrjournals.org/content/early/2010/10/07/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-1335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955801PMC
October 2010

Using DNA methylation patterns to infer tumor ancestry.

PLoS One 2010 Aug 9;5(8):e12002. Epub 2010 Aug 9.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012002PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918495PMC
August 2010

Hormone therapy, DNA methylation and colon cancer.

Carcinogenesis 2010 Jun 11;31(6):1060-7. Epub 2010 Jan 11.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA, USA.

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http://dx.doi.org/10.1093/carcin/bgq009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878358PMC
June 2010

Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer.

PLoS Genet 2010 Apr 22;6(4):e1000917. Epub 2010 Apr 22.

Department of Urology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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https://dx.plos.org/10.1371/journal.pgen.1000917
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http://dx.doi.org/10.1371/journal.pgen.1000917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858672PMC
April 2010

Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns.

Hum Mol Genet 2009 Dec 23;18(24):4808-17. Epub 2009 Sep 23.

Jane Anne Nohl Division of Hematology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddp445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481584PMC
December 2009

Many colorectal cancers are "flat" clonal expansions.

Cell Cycle 2009 Jul 1;8(14):2187-93. Epub 2009 Jul 1.

Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145878PMC
http://dx.doi.org/10.4161/cc.8.14.9151DOI Listing
July 2009

Older individuals appear to acquire mitotically older colorectal cancers.

J Pathol 2009 Mar;217(4):483-8

Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1002/path.2506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418435PMC
March 2009

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers.

Proc Natl Acad Sci U S A 2009 Mar 4;106(12):4828-33. Epub 2009 Mar 4.

Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1073/pnas.0810276106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651202PMC
March 2009

Development and evaluation of new mask protocols for gene expression profiling in humans and chimpanzees.

BMC Bioinformatics 2009 Mar 5;10:77. Epub 2009 Mar 5.

Department of Biochemistry and Molecular Biology, University of Southern California, Los Angeles, CA 90089, USA.

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http://www.biomedcentral.com/1471-2105/10/77
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http://dx.doi.org/10.1186/1471-2105-10-77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660304PMC
March 2009

mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft.

BMC Genomics 2008 Nov 3;9:521. Epub 2008 Nov 3.

Department of Biochemistry and Molecular Biology, University of Southern California, 2250 Alcazar Street, IGM 240, Los Angeles, CA 90089, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-9-521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612029PMC
November 2008

Modeling DNA methylation in a population of cancer cells.

Stat Appl Genet Mol Biol 2008 22;7(1):Article 18. Epub 2008 Jun 22.

USC Keck School of Medicine, University of Southern California, USA.

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https://www.degruyter.com/view/j/sagmb.2008.7.1/sagmb.2008.7
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http://dx.doi.org/10.2202/1544-6115.1374DOI Listing
September 2008

Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer.

Mol Cancer 2008 Jul 10;7:62. Epub 2008 Jul 10.

Department of Surgery, Norris Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90089-9176, USA.

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http://dx.doi.org/10.1186/1476-4598-7-62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483990PMC
July 2008

Inferring relative numbers of human leucocyte genome replications.

Br J Haematol 2008 Jun 10;141(6):862-71. Epub 2008 Apr 10.

Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07142.xDOI Listing
June 2008

DNA methylation profile of 28 potential marker loci in malignant mesothelioma.

Lung Cancer 2007 Nov 30;58(2):220-30. Epub 2007 Jul 30.

Norris Cancer Center and Department of Surgery, Keck School of Medicine, University of Southern California, Room NOR6420, 1441 Eastlake Avenue, Los Angeles, CA 90089-9176, USA.

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http://dx.doi.org/10.1016/j.lungcan.2007.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752414PMC
November 2007

DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study.

Cancer Epidemiol Biomarkers Prev 2007 Nov;16(11):2363-72

Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Room 5421A, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0268DOI Listing
November 2007

Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma.

Mol Cancer 2007 Oct 29;6:70. Epub 2007 Oct 29.

Norris Cancer Center and Department of Surgery and of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089-9176, USA.

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http://dx.doi.org/10.1186/1476-4598-6-70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206053PMC
October 2007

Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging.

BMC Med Genet 2007 Jul 31;8:50. Epub 2007 Jul 31.

Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1186/1471-2350-8-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950491PMC
July 2007

Statistical methods for evaluating DNA methylation as a marker for early detection or prognosis.

Dis Markers 2007 ;23(1-2):113-20

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850861PMC
http://dx.doi.org/10.1155/2007/308573DOI Listing
May 2007

XRCC1, XRCC3, and XPD polymorphisms as modifiers of the effect of smoking and alcohol on colorectal adenoma risk.

Cancer Epidemiol Biomarkers Prev 2006 Dec;15(12):2384-90

University of Southern California/Norris Comprehensive Cancer Center, Keck School of Medicine, 1441 Eastlake Avenue, room 5421A, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0381DOI Listing
December 2006

Cluster analysis for DNA methylation profiles having a detection threshold.

BMC Bioinformatics 2006 Jul 26;7:361. Epub 2006 Jul 26.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-7-361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1555616PMC
July 2006

Modeling exposures for DNA methylation profiles.

Cancer Epidemiol Biomarkers Prev 2006 Mar;15(3):567-72

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP 220, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-05-0717DOI Listing
March 2006

Identifying susceptibility genes by using joint tests of association and linkage and accounting for epistasis.

BMC Genet 2005 Dec 30;6 Suppl 1:S147. Epub 2005 Dec 30.

National Oceanic and Atmospheric Administration/National Marine Fisheries Service, Alaska Fisheries Science Center, 7600 Sand Point Way NE, Seattle, WA 98115, USA.

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http://dx.doi.org/10.1186/1471-2156-6-S1-S147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866788PMC
December 2005

Testing association and linkage using affected-sib-parent study designs.

Genet Epidemiol 2005 Nov;29(3):225-33

National Oceanic and Atmospheric Administration/National Marine Fisheries Service, Alaska Fisheries Science Center, Seattle, Washington 98115, USA.

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http://dx.doi.org/10.1002/gepi.20091DOI Listing
November 2005

Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma.

Eur J Cancer 2005 Nov 19;41(17):2769-78. Epub 2005 Oct 19.

Department of Urology, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089-9176, USA.

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http://dx.doi.org/10.1016/j.ejca.2005.07.019DOI Listing
November 2005

Age-related human small intestine methylation: evidence for stem cell niches.

BMC Med 2005 Jun 23;3:10. Epub 2005 Jun 23.

Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7
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http://dx.doi.org/10.1186/1741-7015-3-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1168897PMC
June 2005

XRCC1 and XRCC3 polymorphisms and their role as effect modifiers of unsaturated fatty acids and antioxidant intake on colorectal adenomas risk.

Cancer Epidemiol Biomarkers Prev 2005 Mar;14(3):609-15

Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA

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http://dx.doi.org/10.1158/1055-9965.EPI-04-0189DOI Listing
March 2005

Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung.

Lung Cancer 2005 Feb;47(2):193-204

Norris Cancer Center and Department of Surgery and Biochemistry, Room NOR 6420, 1441 Eastlake Ave., Keck School of Medicine, University of Southern California, Los Angeles, CA 90089-9176, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016950020400447
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http://dx.doi.org/10.1016/j.lungcan.2004.08.003DOI Listing
February 2005

Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients.

Clin Cancer Res 2004 Nov;10(22):7457-65

Departments of Urology, Clinical Pathology, and Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089-9176, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-0930DOI Listing
November 2004

A comparison of cluster analysis methods using DNA methylation data.

Bioinformatics 2004 Aug 25;20(12):1896-904. Epub 2004 Mar 25.

Department of Preventive Medicine, Norris Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles 90089, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/bth176DOI Listing
August 2004

Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen.

Cancer Res 2004 Jun;64(11):3807-13

Department of Urology, University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, California, 90089-9176, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-03-3852DOI Listing
June 2004

Diet, cancer and aging in DNA mismatch repair deficient mice.

Carcinogenesis 2002 Nov;23(11):1807-10

Department of Pathology, Molecular Biology and Surgery, Norris Cancer Center, University of Southern California School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1093/carcin/23.11.1807DOI Listing
November 2002

Analysis of complex methylation data.

Methods 2002 Jun;27(2):170-8

Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089-9176, USA.

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http://dx.doi.org/10.1016/s1046-2023(02)00071-3DOI Listing
June 2002

Ascertainment bias in family-based case-control studies.

Am J Epidemiol 2002 May;155(9):875-80

Department of Preventive Medicine, University of Southern California, 1540 Alcazar Street, Suite 220, Los Angeles, CA 90089-9011, USA.

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http://dx.doi.org/10.1093/aje/155.9.875DOI Listing
May 2002

Hierarchical clustering of lung cancer cell lines using DNA methylation markers.

Cancer Epidemiol Biomarkers Prev 2002 Mar;11(3):291-7

Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9593, USA.

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March 2002