Kim N Green

Kim N Green

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A limited capacity for microglial repopulation in the adult brain.

Glia 2018 11 28;66(11):2385-2396. Epub 2018 Oct 28.

Department of Neurobiology and Behavior Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, California.

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http://doi.wiley.com/10.1002/glia.23477
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http://dx.doi.org/10.1002/glia.23477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269202PMC
November 2018

Gamma oscillations in the entorhinal-hippocampal circuit underlying memory and dementia.

Neurosci Res 2018 Apr 10;129:40-46. Epub 2018 Feb 10.

Department of Anatomy and Neurobiology, University of California Irvine, United States; Center for the Neurobiology of Learning and Memory, University of California Irvine, United States; Japan Science and Technology Agency, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2018.02.002DOI Listing
April 2018

Necroptosis activation in Alzheimer's disease.

Nat Neurosci 2017 Sep 24;20(9):1236-1246. Epub 2017 Jul 24.

Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1038/nn.4608DOI Listing
September 2017

Microglial repopulation resolves inflammation and promotes brain recovery after injury.

Glia 2017 06 2;65(6):931-944. Epub 2017 Mar 2.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, California, 92697.

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http://dx.doi.org/10.1002/glia.23135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395311PMC
June 2017

Inflammation in Alzheimer's disease: Lessons learned from microglia-depletion models.

Brain Behav Immun 2017 Mar 6;61:1-11. Epub 2016 Jul 6.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2016.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218993PMC
March 2017

Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.

Brain 2016 Apr 26;139(Pt 4):1265-81. Epub 2016 Feb 26.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697-4545, USA

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http://dx.doi.org/10.1093/brain/aww016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006229PMC
April 2016

7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss.

PLoS One 2014 10;9(3):e91453. Epub 2014 Mar 10.

Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, United States of America; Department of Neurobiology and Behavior, University of California Irvine, Irvine, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091453PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948846PMC
March 2016

Characterizing newly repopulated microglia in the adult mouse: impacts on animal behavior, cell morphology, and neuroinflammation.

PLoS One 2015 7;10(4):e0122912. Epub 2015 Apr 7.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders (UCI MIND), University of California, Irvine, Irvine, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122912PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388515PMC
January 2016

Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice.

J Neurochem 2015 Sep 14;134(5):915-26. Epub 2015 Jul 14.

Department of Neurobiology and Behavior and Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, California, USA.

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http://dx.doi.org/10.1111/jnc.13195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792118PMC
September 2015

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice.

J Neuroinflammation 2015 Aug 1;12:139. Epub 2015 Aug 1.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, 3208 Biological Sciences III, Irvine, CA, 92697-4545, USA.

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http://dx.doi.org/10.1186/s12974-015-0366-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522109PMC
August 2015

Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus.

J Neurosci 2015 Jul;35(27):9977-89

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, California 92697, and

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http://dx.doi.org/10.1523/JNEUROSCI.0336-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495246PMC
July 2015

Optical imaging in an Alzheimer's mouse model reveals amyloid--dependent vascular impairment.

Neurophotonics 2014 Jul;1(1):011005

Beckman Laser Institute and Medical Clinic, Laser Microbeam and Medical Program, 1002 Health Sciences Road, Irvine, California 92612 ; University of California Irvine, Department of Biomedical Engineering, 3120 Natural Sciences II, Irvine, California 92697-2715.

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http://dx.doi.org/10.1117/1.NPh.1.1.011005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132842PMC
July 2014

Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production.

Neurobiol Aging 2014 May 30;35(5):1002-11. Epub 2013 Oct 30.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.10.090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939046PMC
May 2014

Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease.

Neurobiol Dis 2014 Apr 14;64:107-17. Epub 2014 Jan 14.

Institute for Memory Impairments and Neurological Disorders, Irvine, CA, USA; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697-4550, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072239PMC
April 2014

Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain.

Neuron 2014 Apr;82(2):380-97

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA 92697-4545, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.02.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161285PMC
April 2014

Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition.

Neurobiol Dis 2014 Feb 29;62:407-15. Epub 2013 Oct 29.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697-4545, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2013.10.019DOI Listing
February 2014

α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles.

Am J Pathol 2014 Feb 19;184(2):520-9. Epub 2013 Nov 19.

Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, California; Department of Neurobiology and Behavior, University of California, Irvine, California. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.10.010DOI Listing
February 2014

In vivo optical signatures of neuronal death in a mouse model of Alzheimer's disease.

Lasers Surg Med 2014 Jan 28;46(1):27-33. Epub 2013 Nov 28.

Laser Microbeam and Medical Program (LAMMP), Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road, Irvine, California, 92612; UC Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND), 2642 Biological Sciences III, Irvine, California, 92697-4545; UC Irvine Dept. of Biomedical Engineering, 3120 Natural Sciences II, Irvine, California, 92697-2715.

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http://dx.doi.org/10.1002/lsm.22206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001800PMC
January 2014

Mifepristone alters amyloid precursor protein processing to preclude amyloid beta and also reduces tau pathology.

Biol Psychiatry 2013 Sep 8;74(5):357-66. Epub 2013 Jan 8.

Department of Neurobiology and Behavior, University of California, Irvine, USA.

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http://dx.doi.org/10.1016/j.biopsych.2012.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633722PMC
September 2013

APP knockout mice experience acute mortality as the result of ischemia.

PLoS One 2012 9;7(8):e42665. Epub 2012 Aug 9.

Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415410PMC
April 2013

Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aβ or tau pathology.

PLoS One 2012 3;7(8):e39566. Epub 2012 Aug 3.

Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039566PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411687PMC
February 2013

Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: implications for lysosomal function.

Brain Res 2012 Dec 24;1489:8-16. Epub 2012 Oct 24.

Department of Neurobiology and Behavior, University of California, Irvine, 3208 Biological Sciences III, Irvine, CA 92697-4545, United States.

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http://dx.doi.org/10.1016/j.brainres.2012.10.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516298PMC
December 2012

Animal models of Alzheimer disease.

Cold Spring Harb Perspect Med 2012 Nov 1;2(11). Epub 2012 Nov 1.

Institute for Memory Impairments and Neurological Disorders, Department of Neurobiology and Behavior, University of California, Irvine, 92697-4545, USA.

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http://dx.doi.org/10.1101/cshperspect.a006320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543097PMC
November 2012

Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice.

Am J Pathol 2012 Aug 9;181(2):616-25. Epub 2012 Jun 9.

Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, California 92697-4545, USA.

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http://dx.doi.org/10.1016/j.ajpath.2012.04.020DOI Listing
August 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan 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Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.4161/auto.19496DOI Listing
April 2012

Presenilins mediate efficient proteolysis via the autophagosome-lysosome system.

Autophagy 2011 Jun 1;7(6):664-5. Epub 2011 Jun 1.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, USA.

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June 2011

ST101 induces a novel 17 kDa APP cleavage that precludes Aβ generation in vivo.

Ann Neurol 2011 May 17;69(5):831-44. Epub 2011 Mar 17.

From the Department of Neurobiology and Behavior Institute for Memory Impairments and Neurological Disorders, University of California at Irvine, Irvine, CA 92697-4545, USA.

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May 2011

Spatial frequency domain imaging of intrinsic optical property contrast in a mouse model of Alzheimer's disease.

Ann Biomed Eng 2011 Apr 19;39(4):1349-57. Epub 2011 Feb 19.

Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road, Irvine, CA 92612, USA.

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April 2011

Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a γ-secretase-independent manner.

J Neurosci 2011 Feb;31(8):2781-91

Department of Neurobiology and Behavior and Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, California 92697-4545, USA.

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February 2011

Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation.

J Alzheimers Dis 2010 ;21(2):527-42

Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697-4545, USA.

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December 2010

Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease.

PLoS One 2010 Nov 17;5(11):e14015. Epub 2010 Nov 17.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, United States of America.

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November 2010

Oligemic hypoperfusion differentially affects tau and amyloid-{beta}.

Am J Pathol 2010 Jul 14;177(1):300-10. Epub 2010 May 14.

Department of Neurobiology and Behavior, Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, 3212 Biological Sciences III, Irvine, CA 92697-4545, USA.

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July 2010

Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice.

Am J Pathol 2010 Feb 30;176(2):870-80. Epub 2009 Dec 30.

Department of Neurobiology and Behavior, University of California, Irvine, 3400A Biological Sciences III, Irvine, CA 92697-4545, USA.

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February 2010

Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology.

Authors:
Kim N Green

J Cell Mol Med 2009 Sep 24;13(9A):2787-99. Epub 2009 Jul 24.

Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697-4545, USA.

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September 2009

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

Proc Natl Acad Sci U S A 2009 Aug 24;106(32):13594-9. Epub 2009 Jul 24.

Department of Neurobiology and Behavior and Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697, USA.

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August 2009

Relevance of transgenic mouse models to human Alzheimer disease.

J Biol Chem 2009 Mar 22;284(10):6033-7. Epub 2008 Oct 22.

Department of Neurobiology and Behavior and Institute for Brain Aging and Dementia, University of California, Irvine, California 92697-4545, USA.

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March 2009

Abeta inhibits the proteasome and enhances amyloid and tau accumulation.

Neurobiol Aging 2008 Nov 1;29(11):1607-18. Epub 2007 Jun 1.

Department of Neurobiology and Behavior, University of California, 1109 Gillespie Neuroscience Research Facility, Irvine, CA 92697-4545, USA.

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November 2008

Linking calcium to Abeta and Alzheimer's disease.

Neuron 2008 Jul;59(2):190-4

Department of Neurobiology and Behavior and Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA 92697-4545, USA.

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July 2008

SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.

J Cell Biol 2008 Jun;181(7):1107-16

Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA.

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June 2008

Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals.

Cell Calcium 2005 Sep-Oct;38(3-4):427-37

Department of Neurobiology and Behavior, University of California, 1109 Gillespie Neuroscience Building, Irvine CA 92697-4545, USA.

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May 2008

Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice.

Neurobiol Dis 2007 Oct 23;28(1):76-82. Epub 2007 Jun 23.

Department of Neurobiology and Behavior, 1109 Gillespie Neuroscience Research Facility, University of California, Irvine, Irvine, CA 92697-4545, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756084PMC
October 2007

Intracellular amyloid-beta in Alzheimer's disease.

Nat Rev Neurosci 2007 Jul;8(7):499-509

Department of Neurobiology and Behaviour, and Institute for Brain Aging and Dementia, University of California, Irvine, California 92697-4545, USA.

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July 2007

Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice.

J Neurosci 2007 Jan;27(4):751-61

Department of Neurobiology and Behavior, Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, California 92697-4545, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672918PMC
January 2007

Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease.

J Neurosci 2006 Aug;26(35):9047-56

Department of Neurobiology and Behavior, and Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, California 92697-4545, USA.

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August 2006

Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice.

Am J Pathol 2006 Jun;168(6):1986-97

Department of Neurobiology and Behavior, 1109 Gillespie Neuroscience Facility, University of California, Irvine, Irvine, CA 92697-4545, USA.

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http://dx.doi.org/10.2353/ajpath.2006.051232DOI Listing
June 2006

M1 receptors play a central role in modulating AD-like pathology in transgenic mice.

Neuron 2006 Mar;49(5):671-82

Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697, USA.

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http://dx.doi.org/10.1016/j.neuron.2006.01.020DOI Listing
March 2006

A dynamic relationship between intracellular and extracellular pools of Abeta.

Am J Pathol 2006 Jan;168(1):184-94

Department of Neurobiology and Behavior, University of California, Irvine, 1109 Gillespie Neuroscience Bldg., Irvine, CA 92697-4545, USA.

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http://dx.doi.org/10.2353/ajpath.2006.050593DOI Listing
January 2006

A central role for ROS in the functional remodelling of L-type Ca2+ channels by hypoxia.

Philos Trans R Soc Lond B Biol Sci 2005 Dec;360(1464):2247-54

University of Leeds School of Medicine Worsley Building, Leeds LS2 9JT, UK.

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December 2005

Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease.

J Neurochem 2005 Sep;94(6):1711-8

Department of Neurobiology and Behavior, University of California, Irvine, California 92697-4545, USA.

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September 2005

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice.

Neuron 2005 Mar;45(5):675-88

Department of Neurobiology and Behavior and Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA 92697, USA.

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March 2005

Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease.

Proc Natl Acad Sci U S A 2005 Feb 10;102(8):3046-51. Epub 2005 Feb 10.

Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA.

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February 2005

Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways.

Brain Res Mol Brain Res 2004 Nov;130(1-2):161-9

Institute for Cardiovascular Research, Worsley Medical and Dental Building, University of Leeds, Leeds LS2 9JT, United Kingdom.

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November 2004

Presenilin regulates capacitative calcium entry dependently and independently of gamma-secretase activity.

Biochem Biophys Res Commun 2004 Oct;322(4):1145-52

Department of Neurobiology and Behavior, University of California, Irvine, CA 92697-4545, USA.

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http://dx.doi.org/10.1016/j.bbrc.2004.07.136DOI Listing
October 2004

Amyloid peptide-mediated hypoxic regulation of Ca2+ channels in PC12 cells.

Adv Exp Med Biol 2003 ;536:187-92

Institute for Cardiovascular Research, Worsley Medical and Dental Building, University of Leeds, Leeds LS2 9JT, UK.

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August 2004

Hypoxic remodelling of Ca2+ mobilization in type I cortical astrocytes: involvement of ROS and pro-amyloidogenic APP processing.

J Neurochem 2004 Feb;88(4):869-77

Institute for Cardiovascular Research School of Biomedical Sciences, University of Leeds, Leeds, UK.

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February 2004

Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential.

Org Biomol Chem 2003 Dec 4;1(23):4317-22. Epub 2003 Nov 4.

School of Biological and Chemical Sciences, University of Exeter, Stocker Road, Exeter, UK EX4 4QD.

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December 2003

Altered processing of amyloid precursor protein in the human neuroblastoma SH-SY5Y by chronic hypoxia.

J Neurochem 2002 Dec;83(6):1262-71

Institute for Cardiovascular Research, University of Leeds, Leeds, UK.

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December 2002

Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB.

J Neurochem 2002 Jun;81(5):1043-51

Institute for Cardiovascular Research, University of Leeds, Leeds, UK.

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June 2002