Kim E Nichols

Kim E Nichols

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Kim E Nichols

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Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society.

J Allergy Clin Immunol Pract 2018 Sep - Oct;6(5):1508-1517. Epub 2018 Jul 4.

Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, and Theme of Children's and Women's Health, Karolinska University Hospital Solna, Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132198183038
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http://dx.doi.org/10.1016/j.jaip.2018.05.031DOI Listing
November 2019

Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: Recommendations from the North American Consortium for Histiocytosis (NACHO).

Pediatr Blood Cancer 2019 Nov 24;66(11):e27929. Epub 2019 Jul 24.

Division of Pediatric Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1002/pbc.27929DOI Listing
November 2019

Recent advances in genetic predisposition to pediatric acute lymphoblastic leukemia.

Expert Rev Hematol 2019 Nov 19:1-16. Epub 2019 Nov 19.

Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1080/17474086.2020.1685866DOI Listing
November 2019

Synergistic TLR/IFNα/β-Signaling Facilitates Escape of IL-18 Expression from Endotoxin Tolerance.

Am J Respir Crit Care Med 2019 Nov 11. Epub 2019 Nov 11.

University Hospital Munster, 39069, Pediatric Rheumatology and Immunology, Muenster, Germany;

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http://dx.doi.org/10.1164/rccm.201903-0659OCDOI Listing
November 2019

SLAM-SAP-Fyn: Old Players with New Roles in iNKT Cell Development and Function.

Int J Mol Sci 2019 Sep 27;20(19). Epub 2019 Sep 27.

Department of Physiology, College of Human Medicine, Michigan State University, East Lansing, MI 48824, USA.

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http://dx.doi.org/10.3390/ijms20194797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801923PMC
September 2019

Association of Germline BRCA2 Mutations With the Risk of Pediatric or Adolescent Non-Hodgkin Lymphoma.

JAMA Oncol 2019 Jul 25. Epub 2019 Jul 25.

Department of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1001/jamaoncol.2019.2203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659356PMC
July 2019

Recommendations for the management of hemophagocytic lymphohistiocytosis in adults.

Blood 2019 Jun 16;133(23):2465-2477. Epub 2019 Apr 16.

Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institute, and Theme of Children's and Women's Health, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1182/blood.2018894618DOI Listing
June 2019

Somatic and germline genomics in paediatric acute lymphoblastic leukaemia.

Nat Rev Clin Oncol 2019 04;16(4):227-240

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://www.nature.com/articles/s41571-018-0136-6
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http://dx.doi.org/10.1038/s41571-018-0136-6DOI Listing
April 2019

The Immunology of Macrophage Activation Syndrome.

Front Immunol 2019 1;10:119. Epub 2019 Feb 1.

Pediatric Rheumatology, University of Alabama Birmingham, Birmingham, AL, United States.

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http://dx.doi.org/10.3389/fimmu.2019.00119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367262PMC
February 2019

Microbiota-dependent signals are required to sustain TLR-mediated immune responses.

JCI Insight 2019 Jan 10;4(1). Epub 2019 Jan 10.

Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1172/jci.insight.124370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485364PMC
January 2019

Two-year-old female with EBV-positive diffuse large B-cell lymphoma and subsequent CNS involvement with neurolymphomatosis.

Pediatr Blood Cancer 2018 12 27;65(12):e27415. Epub 2018 Aug 27.

Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.27415DOI Listing
December 2018

Parent-child communication surrounding genetic testing for Li-Fraumeni syndrome: Living under the cloud of cancer.

Pediatr Blood Cancer 2018 11 15;65(11):e27350. Epub 2018 Jul 15.

Division of Cancer Predisposition, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.27350DOI Listing
November 2018

Genetic Risk for Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer.

J Clin Oncol 2018 07 30;36(20):2078-2087. Epub 2018 May 30.

Zhaoming Wang, Carmen L. Wilson, John Easton, Andrew Thrasher, Heather Mulder, Dale J. Hedges, Shuoguo Wang, Michael C. Rusch, Michael N. Edmonson, Jennifer Q. Lanctot, Eric Caron, Kyla Shelton, Kelsey Currie, Matthew Lear, Aman Patel, Celeste Rosencrance, Ying Shao, Bhavin Vadodaria, Donald Yergeau, Yadav Sapkota, Russell J. Brooke, Wonjong Moon, Evadnie Rampersaud, Xiaotu Ma, Ti-Cheng Chang, Stephen V. Rice, Cynthia Pepper, Xin Zhou, Xiang Chen, Wenan Chen, Matthew J. Ehrhardt, Matthew J. Krasin, Rebecca M. Howell, Nicholas S. Phillips, Courtney Lewis, Deokumar Srivastava, Ching-Hon Pui, Chimene A. Kesserwan, Gang Wu, Kim E. Nichols, James R. Downing, Melissa M. Hudson, Yutaka Yasui, Leslie L. Robison, and Jinghui Zhang, St Jude Children's Research Hospital, Memphis, TN; Qi Liu, University of Alberta, Edmonton, Alberta, Canada; Shawn Levy, Angela Jones, and Braden Boone, HudsonAlpha Institute for Biotechnology, Huntsville, AL; and Rebecca M. Howell, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://ascopubs.org/doi/10.1200/JCO.2018.77.8589
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http://dx.doi.org/10.1200/JCO.2018.77.8589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036620PMC
July 2018

The Influence of Adolescence on Parents' Perspectives of Testing and Discussing Inherited Cancer Predisposition.

J Genet Couns 2018 Jun 16. Epub 2018 Jun 16.

Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s10897-018-0267-zDOI Listing
June 2018

TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children.

J Clin Oncol 2018 02 4;36(6):591-599. Epub 2018 Jan 4.

Maoxiang Qian, Xueyuan Cao, Wenjian Yang, Cheng Cheng, Hui Zhang, Takaya Moriyama, Gerard Zambetti, Kim E. Nichols, Ching-Hon Pui, Charles G. Mullighan, William E. Evans, Mary V. Relling, and Jun J. Yang, St Jude Children's Research Hospital, Memphis, TN; Meenakshi Devidas and Yunfeng Dai, University of Florida, Gainesville, FL; Andrew Carroll, University of Alabama at Birmingham, Birmingham, AL; Nyla A. Heerema and Julie M. Gastier-Foster, The Ohio State University and Wexner Medical Center; Julie M. Gastier-Foster and Elaine R. Mardis, Nationwide Children's Hospital, Columbus, OH; Hui Zhang, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong; Heng Xu, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China; Elizabeth Raetz, University of Utah, Salt Lake City, UT; Eric Larsen, Maine Children's Cancer Program, Scarborough, ME; Naomi Winick, University of Texas Southwestern Medical Center, Dallas; W. Paul Bowman, Cook Children's Medical Center, Fort Worth, TX; Paul L. Martin, Duke University, Durham, NC; Robert Fulton, Washington University School of Medicine, St Louis, MO; Michael Borowitz, Johns Hopkins Medical Institute, Baltimore, MD; Brent Wood, University of Washington, Seattle, WA; William L. Carroll, New York University, New York, NY; Stephen P. Hunger, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA; and Mignon L. Loh, Benioff Children's Hospital and University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2017.75.5215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815403PMC
February 2018

Clear cell sarcoma of kidney involving a horseshoe kidney and harboring EGFR internal tandem duplication.

Pediatr Blood Cancer 2017 Nov 25;64(11). Epub 2017 Apr 25.

Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.26602DOI Listing
November 2017

The Future of Surveillance in the Context of Cancer Predisposition: Through the Murky Looking Glass.

Clin Cancer Res 2017 Nov;23(21):e133-e137

Children's Hospital of Philadelphia, and the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2026DOI Listing
November 2017

The genomic landscape of pediatric myelodysplastic syndromes.

Nat Commun 2017 11 16;8(1):1557. Epub 2017 Nov 16.

Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 342, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41467-017-01590-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691144PMC
November 2017

Should Genetic Testing be Offered for Children? The Perspectives of Adolescents and Emerging Adults in Families with Li-Fraumeni Syndrome.

J Genet Couns 2017 Oct 16;26(5):1106-1115. Epub 2017 Mar 16.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s10897-017-0091-xDOI Listing
October 2017

Go with the flow: perforin and CD107a in HLH.

Blood 2017 06;129(22):2954-2955

ST JUDE CHILDREN'S RESEARCH HOSPITAL.

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http://dx.doi.org/10.1182/blood-2017-04-773192DOI Listing
June 2017

Ethical considerations surrounding germline next-generation sequencing of children with cancer.

Expert Rev Mol Diagn 2017 May;17(5):523-534

b Division of Cancer Predisposition , St. Jude Children's Research Hospital , Memphis , TN , USA.

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http://dx.doi.org/10.1080/14737159.2017.1316665DOI Listing
May 2017

Salvage therapy for refractory hemophagocytic lymphohistiocytosis: A review of the published experience.

Pediatr Blood Cancer 2017 04 27;64(4). Epub 2016 Oct 27.

Children's Cancer Center, Staten Island University Hospital at Northwell Health, Staten Island, New York.

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http://dx.doi.org/10.1002/pbc.26308DOI Listing
April 2017

Cancer predisposition syndromes associated with myeloid malignancy.

Semin Hematol 2017 04 7;54(2):115-122. Epub 2017 Apr 7.

Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00371963173004
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http://dx.doi.org/10.1053/j.seminhematol.2017.04.003DOI Listing
April 2017

Li-Fraumeni syndrome: a paradigm for the understanding of hereditary cancer predisposition.

Br J Haematol 2017 02 16;176(4):539-552. Epub 2016 Dec 16.

Division of Cancer Predisposition, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/bjh.14461DOI Listing
February 2017

The Advantages and Challenges of Testing Children for Heritable Predisposition to Cancer.

Am Soc Clin Oncol Educ Book 2016 ;35:251-69

From the Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN; Departments of Pediatrics, Medicine, and Surgery, MacLean Center for Clinical Medical Ethics, The University of Chicago, Chicago, IL; Department of Medicine, Department of Medical Ethics and Health Policy, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1200/EDBK_160621DOI Listing
January 2017

Introduction to cancer genetic susceptibility syndromes.

Hematology Am Soc Hematol Educ Program 2016 Dec;2016(1):293-301

Division of Cancer Predisposition, St. Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1182/asheducation-2016.1.293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142512PMC
December 2016

Primary immunodeficiencies associated with EBV-Induced lymphoproliferative disorders.

Crit Rev Oncol Hematol 2016 Dec 2;108:109-127. Epub 2016 Nov 2.

Research Center for Immunodeficiencies, Children's Medical School, Tehran University of Medical Sciences, Tehran, Iran; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Systematic Review and Meta-Analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2016.10.014DOI Listing
December 2016

Genome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility.

J Clin Oncol 2016 Oct;34(30):3697-3704

Nardin Samuel, Gavin Wilson, James Tran, Meredith Irwin, Rosanna Weksberg, Thomas J. Hudson, and David Malkin, University of Toronto; Nardin Samuel, Badr Id Said, Youliang Lou, Weili Li, Ana Novokmet, James Tran, Sanaa Choufani, Marc Remke, Vijay Ramaswamy, Florence M.G. Cavalli, Michael D. Taylor, Uri Tabori, Meredith Irwin, Rosanna Weksberg, Jonathan D. Wasserman, Andrew D. Paterson, and David Malkin, The Hospital for Sick Children; Nardin Samuel, Gavin Wilson, Mathieu Lemire, and Thomas J. Hudson, Ontario Institute for Cancer Research; Christine Elser, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Diana Merino, National Institutes of Health, Bethesda, MD; Kim E. Nichols, St Jude Children's Research Hospital, Memphis, TN; Jonathan L. Finlay, Nationwide Children's Hospital, Columbus, OH; Lynn Meister, Joe DiMaggio Children's Hospital, Hollywood, FL; Jordan R. Hansford, Children's Cancer Centre, Royal Children's Hospital, Melbourne, Victoria, Australia; and Maria Isabel W. Achatz, Hospital AC Camargo, São Paulo, Brazil.

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http://dx.doi.org/10.1200/JCO.2016.67.6940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366343PMC
October 2016

Genetic Predisposition to Neonatal Tumors.

Curr Pediatr Rev 2015 ;11(3):164-78

Division of Cancer Predisposition, St. Jude Children's Research Hospital, 262 Danny Thomas Drive, Memphis, TN 38105, USA.

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http://dx.doi.org/10.2174/1573396311666150714110229DOI Listing
July 2016

Unique Familial MLL(KMT2A)-Rearranged Precursor B-Cell Infant Acute Lymphoblastic Leukemia in Non-twin Siblings.

Pediatr Blood Cancer 2016 07 21;63(7):1175-80. Epub 2016 Mar 21.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/pbc.25957DOI Listing
July 2016

Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition.

Nat Commun 2016 05 25;7:11686. Epub 2016 May 25.

Department of Biomedical Sciences, University of Ulsan College of Medicine, 86 Asanbyeongwon-Gil, Seoul 138-735, Korea.

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http://www.nature.com/doifinder/10.1038/ncomms11686
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http://dx.doi.org/10.1038/ncomms11686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894962PMC
May 2016

Identification, management, and evaluation of children with cancer-predisposition syndromes.

Am Soc Clin Oncol Educ Book 2012 :576-84

From the Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Children's Hospital of Philadelphia, Philadelphia, PA; Huntsman Cancer Institute, Salt Lake City, UT; Center for Children's Cancer Research (C3R), Huntsman Cancer Institute, Salt Lake City, UT.

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http://dx.doi.org/10.14694/EdBook_AM.2012.32.576DOI Listing
April 2016

Reply to "Whole-Body MRI Screening in Children With Li-Fraumeni and Other Cancer-Predisposition Syndromes.".

AJR Am J Roentgenol 2016 Mar;206(3):W53

3 St. Jude's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.2214/AJR.15.15646DOI Listing
March 2016

Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1.

Sci Transl Med 2016 Jan;8(321):321ra7

Department of Translational Medicine and Institute for Research and Cure of Autoimmune Diseases, University of Piemonte Orientale, 28100 Novara, Italy. School of Medicine, University Vita e Salute San Raffaele, 20132 Milan, Italy.

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http://dx.doi.org/10.1126/scitranslmed.aad1565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918505PMC
January 2016

Predisposition to pediatric and hematologic cancers: a moving target.

Am Soc Clin Oncol Educ Book 2014 :e44-55

From the Division of Hematology/Oncology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA; and Division of Pediatric Hematology/Oncology, Department of Pediatrics and Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.

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http://dx.doi.org/10.14694/EdBook_AM.2014.34.e44DOI Listing
December 2015

Germline Mutations in Predisposition Genes in Pediatric Cancer.

N Engl J Med 2015 Dec 18;373(24):2336-2346. Epub 2015 Nov 18.

Departments of Computational Biology (J.Z., G.W., M.N.E., D.H., X.M., X.Z., M.R.W., X.C., M.R., A.P., J.B.B., S.W.), Oncology (M.F.W., T.A.G., R.B.M., S.H.-D., R.N., E.Q., A.G., A.S.P., C.-H.P., K.E.N.), and Pathology (T.A.G., M.R.W., S.A.S., D.W.E., C.-H.P., J.R.D.) and the Pediatric Cancer Genome Project (J.Z., M.F.W., G.W., M.N.E., T.A.G., J.E., X.M., D.A.Y., B.V., X.C., R.B.M., S.H.-D., R.N., E.Q., S.A.S., M.R., A.P., J.B.B., S.W., M.S.W., A.G., D.W.E., A.S.P., C.-H.P., K.E.N., J.R.D.), St. Jude Children's Research Hospital, Memphis, TN; and the Department of Genetics and McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis (L.D., E.R.M., R.K.W.).

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http://dx.doi.org/10.1056/NEJMoa1508054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734119PMC
December 2015

Diagnostic Performance of Whole-Body MRI as a Tool for Cancer Screening in Children With Genetic Cancer-Predisposing Conditions.

AJR Am J Roentgenol 2015 Aug;205(2):400-8

1 Department of Radiology, The Children's Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104.

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http://dx.doi.org/10.2214/AJR.14.13663DOI Listing
August 2015

Genotype Versus Phenotype: The Yin and Yang of Germline TP53 Mutations in Li-Fraumeni Syndrome.

J Clin Oncol 2015 Jul 22;33(21):2331-3. Epub 2015 Jun 22.

The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://ascopubs.org/doi/10.1200/JCO.2015.61.5757
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http://dx.doi.org/10.1200/JCO.2015.61.5757DOI Listing
July 2015

Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia.

PLoS Genet 2015 Jun 23;11(6):e1005262. Epub 2015 Jun 23.

Department of Medicine, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, United States of America; Cancer Biology and Genetics Program, Sloan Kettering Institute, New York, New York, United States of America; Weill Cornell Medical College, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477877PMC
June 2015

Diagnosis of 9q22.3 microdeletion syndrome in utero following identification of craniosynostosis, overgrowth, and skeletal anomalies.

Am J Med Genet A 2015 Apr 23;167A(4):862-5. Epub 2015 Feb 23.

Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://doi.wiley.com/10.1002/ajmg.a.37013
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http://dx.doi.org/10.1002/ajmg.a.37013DOI Listing
April 2015

Parent decision-making around the genetic testing of children for germline TP53 mutations.

Cancer 2015 Jan 15;121(2):286-93. Epub 2014 Sep 15.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/cncr.29027DOI Listing
January 2015

Invariant NKT cells: Killers and conspirators against cancer.

Oncoimmunology 2013 Dec 3;2(12):e27440. Epub 2014 Jan 3.

Division of Oncology; Children's Hospital of Philadelphia; Philadelphia, PA USA.

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http://dx.doi.org/10.4161/onci.27440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926875PMC
December 2013

Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function.

Blood 2013 Apr 13;121(16):3135-46. Epub 2013 Feb 13.

Division of Transfusion Medicine and Therapeutic Pathology, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://www.bloodjournal.org/content/121/16/3135.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2012-12-47
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http://dx.doi.org/10.1182/blood-2012-12-474361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630829PMC
April 2013

An unusual case of gastrointestinal bleeding.

Case Rep Pediatr 2011 22;2011:748543. Epub 2012 Jan 22.

Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Perelman, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1155/2011/748543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350036PMC
August 2012

Rapamycin does not control hemophagocytic lymphohistiocytosis in LCMV-infected perforin-deficient mice.

Pediatr Blood Cancer 2011 Dec 16;57(7):1239-43. Epub 2011 Jun 16.

Division of Hematology/Oncology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1002/pbc.23226DOI Listing
December 2011

Primary immunodeficiency diseases associated with increased susceptibility to viral infections and malignancies.

J Allergy Clin Immunol 2011 Jun 22;127(6):1329-41.e2; quiz 1342-3. Epub 2011 Apr 22.

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.jaci.2011.02.047DOI Listing
June 2011

Eye findings in X-linked lymphoproliferative disorder.

Retina 2011 Apr;31(4):790-7

Scheie Eye Institute, and Department of Ophthalmology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1097/IAE.0b013e318206cd67DOI Listing
April 2011

Educational paper: screening in cancer predisposition syndromes: guidelines for the general pediatrician.

Eur J Pediatr 2011 Mar 6;170(3):285-94. Epub 2011 Jan 6.

Division of Oncology, Children's Hospital of Philadelphia, Colket Translational Research Building, Rm 3012, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00431-010-1377-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086787PMC
March 2011

X-linked lymphoproliferative syndrome: a genetic condition typified by the triad of infection, immunodeficiency and lymphoma.

Br J Haematol 2011 Jan 18;152(1):13-30. Epub 2010 Nov 18.

Molecular Immunology Research Center, Department of Immunology, and School of Medicine, and Research Group for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Dr Qarib Street, Keshavarz Boulevard, Tehran, Iran.

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http://dx.doi.org/10.1111/j.1365-2141.2010.08442.xDOI Listing
January 2011

Transcriptional control of invariant NKT cell development.

Immunol Rev 2010 Nov;238(1):195-215

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2010.00962.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965566PMC
November 2010

BRAF, a piece of the LCH puzzle.

Blood 2010 Sep;116(11):1825-7

Children's Hospital of Philadelphia, and Kimmel Comprehensive Cancer Center at Johns Hopkins School of Medicine.

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http://dx.doi.org/10.1182/blood-2010-06-289934DOI Listing
September 2010