Kim Boekelheide

Kim Boekelheide

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Kim Boekelheide

Publications by authors named "Kim Boekelheide"

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Spermatozoal large RNA content is associated with semen characteristics, sociodemographic and lifestyle factors.

PLoS One 2019 23;14(5):e0216584. Epub 2019 May 23.

Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216584PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532849PMC
January 2020

Trichloroethylene exposure alters dimethylated histone three lysine four in protein kinase A signaling pathway chromatin of rat sperm†.

Biol Reprod 2019 Nov;101(5):875-877

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1093/biolre/ioz155DOI Listing
November 2019

Corrigendum to "Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells" [Toxicol. Lett. 290 (2018) 55-61].

Toxicol Lett 2019 Oct 26;313:208. Epub 2019 Jun 26.

Reproductive Toxicology Branch, Toxicity Assessment Division, National Health and Environmental Effects Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2019.06.001DOI Listing
October 2019

Serum dioxin and DNA methylation in the sperm of operation ranch hand veterans exposed to Agent Orange.

Environ Health 2019 10 29;18(1):91. Epub 2019 Oct 29.

Department of Pathology and Laboratory Medicine, Brown University School of Public Health, Providence, RI, 02912, USA.

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http://dx.doi.org/10.1186/s12940-019-0533-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819394PMC
October 2019

Small RNAs in Rat Sperm Are a Predictive and Sensitive Biomarker of Exposure to the Testicular Toxicant Ethylene Glycol Monomethyl Ether.

Toxicol Sci 2019 06;169(2):399-408

Department of pathology and laboratory medicine, Brown University, Providence, Rhode Island 02912.

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http://dx.doi.org/10.1093/toxsci/kfz041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934889PMC
June 2019

Differential toxicity of water versus gavage exposure to trichloroethylene in rats.

Environ Toxicol Pharmacol 2019 May 16;68:1-3. Epub 2019 Feb 16.

Department of Pathology and Laboratory Medicine, Brown University, 70 Ship Street Rm. 510, Box G-E5, Providence, Rhode Island, 02912, United States.

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http://dx.doi.org/10.1016/j.etap.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594756PMC
May 2019

Localization of dimethylated histone three lysine four in the Rattus norvegicus sperm genome.

Biol Reprod 2018 08;99(2):266-268

Brown University, Department of Pathology and Laboratory Medicine, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1093/biolre/ioy051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454492PMC
August 2018

Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells.

Toxicol Lett 2018 Jun 20;290:55-61. Epub 2018 Mar 20.

Reproductive Toxicology Branch, Toxicity Assessment Division, National Health and Environmental Effects Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2018.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921076PMC
June 2018

Spontaneous testicular atrophy occurs despite normal spermatogonial proliferation in a Tp53 knockout rat.

Andrology 2017 11 22;5(6):1141-1152. Epub 2017 Aug 22.

Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.

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http://doi.wiley.com/10.1111/andr.12409
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http://dx.doi.org/10.1111/andr.12409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673550PMC
November 2017

Ghrelin modulates testicular damage in a cryptorchid mouse model.

PLoS One 2017 18;12(5):e0177995. Epub 2017 May 18.

Division of Urology, Rhode Island Hospital, Providence, RI, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177995PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436858PMC
September 2017

Estradiol Exposure Differentially Alters Monolayer versus Microtissue MCF-7 Human Breast Carcinoma Cultures.

PLoS One 2016 5;11(7):e0157997. Epub 2016 Jul 5.

Department of Pathology and Laboratory Medicine, Brown University, 70 Ship Street, Providence RI 02903, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157997PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933361PMC
July 2017

Identification of sperm mRNA biomarkers associated with testis injury during preclinical testing of pharmaceutical compounds.

Toxicol Appl Pharmacol 2017 04 4;320:1-7. Epub 2017 Feb 4.

Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2017.02.001DOI Listing
April 2017

From the Cover: Sperm Molecular Biomarkers Are Sensitive Indicators of Testicular Injury following Subchronic Model Toxicant Exposure.

Toxicol Sci 2016 10 27;153(2):327-40. Epub 2016 Jul 27.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912.

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https://academic.oup.com/toxsci/article-lookup/doi/10.1093/t
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http://dx.doi.org/10.1093/toxsci/kfw137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036622PMC
October 2016

Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling Pathway.

PLoS One 2016 15;11(4):e0153968. Epub 2016 Apr 15.

Division of Urology, Brown University, Providence, Rhode Island, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153968PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833425PMC
September 2016

Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function.

Sci Rep 2016 07 26;6:28994. Epub 2016 Jul 26.

Center for Alternatives to Animal Testing (CAAT), Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University Baltimore, MD, USA.

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http://dx.doi.org/10.1038/srep28994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960662PMC
July 2016

MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold-Free Hydrogels.

PLoS One 2015 12;10(8):e0135426. Epub 2015 Aug 12.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135426PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534042PMC
May 2016

A human fetal prostate xenograft model of developmental estrogenization.

Int J Toxicol 2015 Mar-Apr;34(2):119-28. Epub 2015 Jan 29.

Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA

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http://dx.doi.org/10.1177/1091581815569364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409475PMC
April 2016

Morphologic effects of estrogen stimulation on 3D MCF-7 microtissues.

Toxicol Lett 2016 Apr 24;248:1-8. Epub 2016 Feb 24.

Department of Pathology and Laboratory Medicine, 70 Ship Street, Brown University, Providence, RI 02903, USA. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2016.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803074PMC
April 2016

Ghrelin ameliorates adhesions in a postsurgical mouse model.

J Surg Res 2016 Mar 5;201(1):226-34. Epub 2015 Nov 5.

Department of Surgery, Division of Urology, Brown University, Providence, Rhode Island; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island. Electronic address:

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http://dx.doi.org/10.1016/j.jss.2015.10.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745993PMC
March 2016

Developmental exposure to estrogen alters differentiation and epigenetic programming in a human fetal prostate xenograft model.

PLoS One 2015 23;10(3):e0122290. Epub 2015 Mar 23.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122290PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370592PMC
February 2016

Di-n-Butyl Phthalate Induces Multinucleated Germ Cells in the Rat Fetal Testis Through a Nonproliferative Mechanism.

Biol Reprod 2015 Nov 23;93(5):110. Epub 2015 Sep 23.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island

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http://dx.doi.org/10.1095/biolreprod.115.131615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712002PMC
November 2015

Into the depths: Techniques for in vitro three-dimensional microtissue visualization.

Biotechniques 2015 Nov 1;59(5):279-86. Epub 2015 Nov 1.

Department of Pathology and Laboratory Medicine, Brown University, Providence, RI.

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http://dx.doi.org/10.2144/000114353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804457PMC
November 2015

Patterns of gene expression and DNA methylation in human fetal and adult liver.

BMC Genomics 2015 Nov 21;16:981. Epub 2015 Nov 21.

Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1186/s12864-015-2066-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654795PMC
November 2015

Architecture of Chimeric Spheroids Controls Drug Transport.

Cancer Microenviron 2015 Aug 4;8(2):101-9. Epub 2015 Aug 4.

Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1007/s12307-015-0171-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542826PMC
August 2015

Xenotransplantation models to study the effects of toxicants on human fetal tissues.

Birth Defects Res B Dev Reprod Toxicol 2014 Dec 4;101(6):410-22. Epub 2014 Dec 4.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.1002/bdrb.21131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526820PMC
December 2014

Practice-based evidence informs environmental health policy and regulation: a case study of residential lead-soil contamination in Rhode Island.

Sci Total Environ 2014 Jan 17;468-469:514-22. Epub 2013 Sep 17.

Brown University Department of Pathology and Laboratory Medicine, Providence, RI 02912, United States; College of Nursing, University of Rhode Island, Kingston, RI 02881, United States. Electronic address:

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http://dx.doi.org/10.1016/j.scitotenv.2013.07.094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858391PMC
January 2014

Cumulative risk: toxicity and interactions of physical and chemical stressors.

Toxicol Sci 2014 Jan 23;137(1):3-11. Epub 2013 Oct 23.

* Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709;

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http://dx.doi.org/10.1093/toxsci/kft228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871930PMC
January 2014

Maturation of the developing human fetal prostate in a rodent xenograft model.

Prostate 2013 Dec 30;73(16):1761-75. Epub 2013 Aug 30.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.1002/pros.22713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306740PMC
December 2013

The current status of biomarkers for predicting toxicity.

Expert Opin Drug Metab Toxicol 2013 Nov 21;9(11):1391-408. Epub 2013 Aug 21.

Drug Safety Research and Development, Pfizer, Inc. , Eastern Point Road, MS 8274 1260, Groton, CT 06340 , USA.

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http://dx.doi.org/10.1517/17425255.2013.827170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870154PMC
November 2013

Biomarkers of chemotherapy-induced testicular damage.

Fertil Steril 2013 Nov;100(5):1192-202

Division of Urology, Rhode Island Hospital, Providence, Rhode Island; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.1016/j.fertnstert.2013.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840355PMC
November 2013

Optimization of a filter-lysis protocol to purify rat testicular homogenates for automated spermatid counting.

J Androl 2012 Sep-Oct;33(5):811-6. Epub 2012 Jan 12.

Department of Pathology and Laboratory Medicine, Brown University, Box G-E5, Providence, RI 02912, USA.

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http://dx.doi.org/10.2164/jandrol.111.015131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598013PMC
March 2013

The new revolution in toxicology: the good, the bad, and the ugly.

Ann N Y Acad Sci 2013 Mar;1278:11-24

Toxicology and Pharmacology Branch, Developmental Therapeutics Program Division of Cancer Treatment and Diagnosis, The National Cancer Institute, National Institutes of Health, Bethesda, MD 20852, USA.

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http://dx.doi.org/10.1111/nyas.12086DOI Listing
March 2013

Induction and persistence of abnormal testicular germ cells following gestational exposure to di-(n-butyl) phthalate in p53-null mice.

J Androl 2012 May-Jun;33(3):505-13. Epub 2011 Aug 25.

Department of Pathology and Laboratory Medicine and the Center for Statistical Sciences, Brown University, Providence, RI, USA.

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http://dx.doi.org/10.2164/jandrol.111.013706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607946PMC
October 2012

Predicting later-life outcomes of early-life exposures.

Environ Health Perspect 2012 Oct 6;120(10):1353-61. Epub 2012 Jun 6.

Department of Pathology and Laboratory Medicine, Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://dels.nas.edu/resources/static-assets/materials-based-
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http://ehp.niehs.nih.gov/1204934
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http://dx.doi.org/10.1289/ehp.1204934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491941PMC
October 2012

Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent.

Toxicol Sci 2012 Oct 14;129(2):235-48. Epub 2012 Jun 14.

Nemours Biomedical Research, Alfred I. duPont Hospital for Children, Wilmington, Delaware 19803, USA.

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http://dx.doi.org/10.1093/toxsci/kfs206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491958PMC
October 2012

SOT/EUROTOX debate: biomarkers from blood and urine will replace traditional histopathological evaluation to determine adverse responses.

Toxicol Sci 2012 Oct;129(2):249-55

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02818, USA.

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http://dx.doi.org/10.1093/toxsci/kfs200DOI Listing
October 2012

Human fetal testis xenografts are resistant to phthalate-induced endocrine disruption.

Environ Health Perspect 2012 Aug 17;120(8):1137-43. Epub 2012 Apr 17.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1289/ehp.1104711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440087PMC
August 2012

Can case study approaches speed implementation of the NRC report: "toxicity testing in the 21st century: a vision and a strategy?".

ALTEX 2011 ;28(3):175-82

The Institute for Chemical Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, NC 27709-2137, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943477PMC
http://dx.doi.org/10.14573/altex.2011.3.175DOI Listing
February 2012

SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice.

FASEB J 2012 Feb 17;26(2):555-66. Epub 2011 Oct 17.

Program for Cancer Therapeutics, Ottawa Hospital Research Institute, Otttawa, Ontario, Canada.

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http://www.fasebj.org/doi/10.1096/fj.11-193979
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http://dx.doi.org/10.1096/fj.11-193979DOI Listing
February 2012

Commentary on "incidence and nature of testicular toxicity findings…".

Authors:
Kim Boekelheide

Birth Defects Res B Dev Reprod Toxicol 2011 Dec 21;92(6):501-3. Epub 2011 Sep 21.

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http://doi.wiley.com/10.1002/bdrb.20319
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http://dx.doi.org/10.1002/bdrb.20319DOI Listing
December 2011

Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways.

PLoS One 2011 20;6(6):e20887. Epub 2011 Jun 20.

Program in Chemical Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020887PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118802PMC
October 2011

A mechanistic redefinition of adverse effects - a key step in the toxicity testing paradigm shift.

ALTEX 2010 ;27(4):243-52

Department of Pathology and Laboratory Medicine, Brown University, Providence, RI 02901, USA.

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http://dx.doi.org/10.14573/altex.2010.4.243DOI Listing
May 2011

Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. I. Histopathological analysis reveals stage dependence of attenuated apoptosis.

Toxicol Sci 2010 Oct 8;117(2):449-56. Epub 2010 Jul 8.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1093/toxsci/kfq203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940404PMC
October 2010

Toxicity testing in the 21st century: using the new toxicity testing paradigm to create a taxonomy of adverse effects.

Toxicol Sci 2010 Mar 21;114(1):20-4. Epub 2009 Dec 21.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1093/toxsci/kfp307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902917PMC
March 2010

Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death.

Mamm Genome 2009 Feb 15;20(2):92-108. Epub 2009 Jan 15.

Division of Biology and Medicine, Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, 70 Ship St., Providence, RI 02903, USA.

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http://dx.doi.org/10.1007/s00335-008-9168-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667228PMC
February 2009

Is gene therapy for the treatment of male infertility feasible?

Nat Clin Pract Urol 2008 Nov 14;5(11):590-3. Epub 2008 Oct 14.

Department of Surgery, Brown University, Providence, RI 02888, USA.

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http://dx.doi.org/10.1038/ncpuro1234DOI Listing
November 2008

Spermatid head retention as a marker of 2,5-hexanedione-induced testicular toxicity in the rat.

Toxicol Pathol 2008 Jun 8;36(4):552-9. Epub 2008 May 8.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02903, USA.

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http://dx.doi.org/10.1177/0192623308317426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574707PMC
June 2008

Mice lacking Raf kinase inhibitor protein-1 (RKIP-1) have altered sperm capacitation and reduced reproduction rates with a normal response to testicular injury.

J Androl 2007 Nov-Dec;28(6):883-90. Epub 2007 Jun 6.

Brown University, Department of Molecular Biology Cell Biology and Biochemistry, Division of Biology and Medicine, 70 Ship Street, Providence, RI 02912, USA.

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http://doi.wiley.com/10.2164/jandrol.107.002964
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http://dx.doi.org/10.2164/jandrol.107.002964DOI Listing
April 2008

Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction.

Cell Signal 2008 Jan 12;20(1):1-9. Epub 2007 Jul 12.

Department of Molecular Biology Cell Biology and Biochemistry, Brown University, Providence, RI 02912, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S089865680700204
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http://dx.doi.org/10.1016/j.cellsig.2007.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231335PMC
January 2008

Time-dependent changes in post-mortem testis histopathology in the rat.

Toxicol Pathol 2007 Aug;35(5):665-71

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1080/01926230701459994DOI Listing
August 2007

Dose-dependent effects of sertoli cell toxicants 2,5-hexanedione, carbendazim, and mono-(2-ethylhexyl) phthalate in adult rat testis.

Toxicol Pathol 2007 Aug;35(5):719-27

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://journals.sagepub.com/doi/10.1080/01926230701481931
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http://dx.doi.org/10.1080/01926230701481931DOI Listing
August 2007

Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone.

Toxicol Sci 2007 Jun 14;97(2):491-503. Epub 2007 Mar 14.

The Hamner Institutes for Health Sciences Centers for Health Research, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfm049DOI Listing
June 2007

NF-kappaB activation elicited by ionizing radiation is proapoptotic in testis.

Biol Reprod 2007 Feb 22;76(2):279-85. Epub 2006 Nov 22.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02903, USA.

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http://dx.doi.org/10.1095/biolreprod.106.054924DOI Listing
February 2007

The Sycp1-Cre transgenic mouse and male germ cell inhibition of NF-kappa b.

J Androl 2006 Nov-Dec;27(6):729-33. Epub 2006 Jun 14.

Department of Pathology and Laboratory Medicine, Brown University, Providence, RI 02903, USA.

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http://dx.doi.org/10.2164/jandrol.106.000950DOI Listing
December 2006

Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact.

Biol Reprod 2005 Sep 18;73(3):482-90. Epub 2005 May 18.

CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1095/biolreprod.104.037184DOI Listing
September 2005

Hybrid GPCR/cadherin (Celsr) proteins in rat testis are expressed with cell type specificity and exhibit differential Sertoli cell-germ cell adhesion activity.

J Androl 2005 Jul-Aug;26(4):529-38

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.2164/jandrol.05003DOI Listing
September 2005

Mechanisms of toxic damage to spermatogenesis.

Authors:
Kim Boekelheide

J Natl Cancer Inst Monogr 2005 (34):6-8

Department of Pathology and Laboratory Medicine, Brown University, Box G-B587, 171 Meeting St., Providence, RI 02912, USA.

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http://dx.doi.org/10.1093/jncimonographs/lgi006DOI Listing
June 2005

NF-kappaB is activated in the rat testis following exposure to mono-(2-ethylhexyl) phthalate.

Biol Reprod 2005 Feb 20;72(2):479-86. Epub 2004 Oct 20.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1095/biolreprod.104.034363DOI Listing
February 2005

Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier.

Drug Metab Dispos 2005 Jan 19;33(1):182-9. Epub 2004 Oct 19.

University of Arizona, 1703 E. Mabel, Tucson, AZ 85721, USA.

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http://dx.doi.org/10.1124/dmd.104.001024DOI Listing
January 2005

Cracking the nut.

Authors:
Kim Boekelheide

Toxicol Sci 2004 Sep;81(1):1-2

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http://dx.doi.org/10.1093/toxsci/kfh196DOI Listing
September 2004

2,5-hexanedione and carbendazim coexposure synergistically disrupts rat spermatogenesis despite opposing molecular effects on microtubules.

Toxicol Sci 2004 Jul 12;80(1):92-100. Epub 2004 May 12.

Department of Pathology and Laboratory Medicine, Brown University, 175 Meeting Street, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1093/toxsci/kfh140DOI Listing
July 2004

Expression and localization of total Akt1 and phosphorylated Akt1 in the rat seminiferous epithelium.

J Androl 2003 Nov-Dec;24(6):891-8

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.1002/j.1939-4640.2003.tb03141.xDOI Listing
January 2004

Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging.

Am J Pathol 2003 Dec;163(6):2595-603

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892386PMC
http://dx.doi.org/10.1016/S0002-9440(10)63614-0DOI Listing
December 2003

gamma-Tubulin overexpression in Sertoli cells in vivo. II: Retention of spermatids, residual bodies, and germ cell apoptosis.

Biol Reprod 2003 Jul 2;69(1):322-30. Epub 2003 Apr 2.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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https://academic.oup.com/biolreprod/article-lookup/doi/10.10
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http://dx.doi.org/10.1095/biolreprod.102.011817DOI Listing
July 2003

gamma-Tubulin overexpression in Sertoli cells in vivo: I. Localization to sites of spermatid head attachment and alterations in Sertoli cell microtubule distribution.

Biol Reprod 2003 Jul 2;69(1):310-21. Epub 2003 Apr 2.

Departments of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1095/biolreprod.102.011791DOI Listing
July 2003

FasL deficiency enhances the development of tumors in p53+/- mice.

Toxicol Pathol 2002 Nov-Dec;30(6):705-13

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1080/01926230290166797DOI Listing
June 2003