Publications by authors named "Kim A Staats"

22Publications

The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications.

Brain 2020 Jun;143(6):1651-1673

KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), Leuven, Belgium.

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http://dx.doi.org/10.1093/brain/awaa022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296858PMC
June 2020

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice.

Hum Mol Genet 2016 08 4;25(16):3491-3499. Epub 2016 Jul 4.

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND)

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http://dx.doi.org/10.1093/hmg/ddw190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179944PMC
August 2016

Dupuytren's disease susceptibility gene, EPDR1, is involved in myofibroblast contractility.

J Dermatol Sci 2016 Aug 7;83(2):131-7. Epub 2016 May 7.

Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, CA, USA; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, CA, USA; Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2016.04.015DOI Listing
August 2016

Genome-wide burden of deleterious coding variants increased in schizophrenia.

Nat Commun 2015 Jul 9;6:7501. Epub 2015 Jul 9.

Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ncomms8501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499856PMC
July 2015

Transcriptional upregulation of myelin components in spontaneous myelin basic protein-deficient mice.

Brain Res 2015 May 20;1606:125-32. Epub 2015 Feb 20.

Autoimmune Genetics Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, University of Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2015.02.021DOI Listing
May 2015

Beta-2 microglobulin is important for disease progression in a murine model for amyotrophic lateral sclerosis.

Front Cell Neurosci 2013 10;7:249. Epub 2013 Dec 10.

KU Leuven Laboratory of Neurobiology and Leuven Research Institute for Neuroscience and Disease (LIND) Leuven, Belgium ; VIB Vesalius Research Center, KU Leuven Leuven, Belgium.

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http://dx.doi.org/10.3389/fncel.2013.00249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857886PMC
December 2013

A novel Zap70 mutation with reduced protein stability demonstrates the rate-limiting threshold for Zap70 in T-cell receptor signalling.

Immunology 2014 Mar;141(3):377-87

Autoimmune Genetics Laboratory, VIB, Leuven, Belgium; Department of Microbiology and Immunology, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/imm.12199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930376PMC
March 2014

Rapamycin increases survival in ALS mice lacking mature lymphocytes.

Mol Neurodegener 2013 Sep 11;8:31. Epub 2013 Sep 11.

Laboratory of Neurobiology, Vesalius Research Center, VIB, Leuven, Belgium.

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http://dx.doi.org/10.1186/1750-1326-8-31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847677PMC
September 2013

Genetic ablation of phospholipase C delta 1 increases survival in SOD1(G93A) mice.

Neurobiol Dis 2013 Dec 19;60:11-7. Epub 2013 Aug 19.

Laboratory of Neurobiology, Belgium; Leuven Research Institute of Neuroscience and Disease (LIND), KU Leuven, Belgium; Vesalius Research Center, VIB, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2013.08.006DOI Listing
December 2013

Neuronal overexpression of IP₃ receptor 2 is detrimental in mutant SOD1 mice.

Biochem Biophys Res Commun 2012 Dec 3;429(3-4):210-3. Epub 2012 Nov 3.

Laboratory of Neurobiology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Belgium.

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http://dx.doi.org/10.1016/j.bbrc.2012.10.094DOI Listing
December 2012

Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism.

Eur J Immunol 2013 Jan 6;43(1):75-84. Epub 2012 Dec 6.

Autoimmune Genetics Laboratory, VIB, Leuven, Belgium.

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http://dx.doi.org/10.1002/eji.201242761DOI Listing
January 2013

Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice.

J Autoimmun 2012 Feb 4;38(1):39-48. Epub 2012 Jan 4.

Autoimmune Genetics Laboratory, VIB and University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.jaut.2011.12.004DOI Listing
February 2012