Kieran Clarke

Kieran Clarke

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Data on uncoupling protein-3 levels, hypoxia, low flow ischemia, and insulin stimulation in dystrophin-deficient mouse hearts.

Data Brief 2018 Oct 8;20:277-280. Epub 2018 Aug 8.

Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford OX1 3PT, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S23523409183086
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http://dx.doi.org/10.1016/j.dib.2018.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106704PMC
October 2018

Prior ingestion of exogenous ketone monoester attenuates the glycaemic response to an oral glucose tolerance test in healthy young individuals.

J Physiol 2018 Apr 2;596(8):1385-1395. Epub 2018 Mar 2.

School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, BC, Canada.

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http://dx.doi.org/10.1113/JP275709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899975PMC
April 2018

A Ketone Ester Drink Lowers Human Ghrelin and Appetite.

Obesity (Silver Spring) 2018 02 6;26(2):269-273. Epub 2017 Nov 6.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://doi.wiley.com/10.1002/oby.22051
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http://dx.doi.org/10.1002/oby.22051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813183PMC
February 2018

The Importance of Calcium Ions for Determining Mitochondrial Glycerol-3-Phosphate Dehydrogenase Activity When Measuring Uncoupling Protein 1 (UCP1) Function in Mitochondria Isolated from Brown Adipose Tissue.

Methods Mol Biol 2018 ;1782:325-336

Trinity Biomedical Science Institute (TBSI), School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-7831-1_19DOI Listing
January 2018

Weighted averaging in spectroscopic studies improves statistical power.

Magn Reson Med 2017 Dec 26;78(6):2082-2094. Epub 2017 Jan 26.

Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/mrm.26615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697704PMC
December 2017

Correction to: Adenosine stress CMR T1-mapping detects early microvascular dysfunction in patients with type 2 diabetes mellitus without obstructive coronary artery disease.

J Cardiovasc Magn Reson 2017 12 7;19(1):99. Epub 2017 Dec 7.

University of Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1186/s12968-017-0406-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719930PMC
December 2017

Adenosine stress CMR T1-mapping detects early microvascular dysfunction in patients with type 2 diabetes mellitus without obstructive coronary artery disease.

J Cardiovasc Magn Reson 2017 Oct 25;19(1):81. Epub 2017 Oct 25.

University of Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1186/s12968-017-0397-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655826PMC
October 2017

A Ketone Ester Drink Increases Postexercise Muscle Glycogen Synthesis in Humans.

Med Sci Sports Exerc 2017 09;49(9):1789-1795

1Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UNITED KINGDOM; and 2Research Institute for Sport and Exercise Sciences, Liverpool John Moore's University, Liverpool, UNITED KINGDOM.

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http://dx.doi.org/10.1249/MSS.0000000000001292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556006PMC
September 2017

Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species.

Int J Biochem Cell Biol 2017 07 5;88:75-83. Epub 2017 May 5.

Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3 PG, United Kingdom.

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http://dx.doi.org/10.1016/j.biocel.2017.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497396PMC
July 2017

Ketone bodies mimic the life span extending properties of caloric restriction.

IUBMB Life 2017 05 3;69(5):305-314. Epub 2017 Apr 3.

Lab of Metabolic Control, NIH/NIAAA, Rockville, MD, USA.

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http://dx.doi.org/10.1002/iub.1627DOI Listing
May 2017

Metabolic Remodeling in Diabetic Cardiomyopathy.

Cardiovasc Res 2017 02 8. Epub 2017 Feb 8.

2 Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital.

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http://dx.doi.org/10.1093/cvr/cvx018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412022PMC
February 2017

The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism.

Am J Physiol Heart Circ Physiol 2016 09 15;311(3):H759-67. Epub 2016 Jul 15.

Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom

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http://dx.doi.org/10.1152/ajpheart.00912.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142182PMC
September 2016

Ectopic and Visceral Fat Deposition in Lean and Obese Patients With Type 2 Diabetes.

J Am Coll Cardiol 2016 07;68(1):53-63

University of Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, Oxford, United Kingdom; Perspectum Diagnostics Ltd., Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.03.597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925621PMC
July 2016

HIV-1-Related Cardiovascular Disease Is Associated With Chronic Inflammation, Frequent Pericardial Effusions, and Probable Myocardial Edema.

Circ Cardiovasc Imaging 2016 Mar;9(3):e004430

From the Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford Centre for Clinical Magnetic Resonance Research, Oxford, United Kingdom (N.N., S.P., V.F., T.K., S.N., C.H.); Division of Cardiology, Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa (N.N., M.B.); Department of Cardiology, St.Vincent's Hospital, Darlinghurst, New South Wales, Australia (E.O., S.E., C.H.); Department of Medicine, University of New South Wales, Sydney, New South Wales, Australia (E.O., S.E., C.H.); Nuffield Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford and John Radcliffe Hospital, Oxford, United Kingdom (L.D., E.W., G.C., G.H.); Department of Physiology, Anatomy and Genetics (P.C., K.C., C.H.) and Oxford NIHR Biomedical Research Centre (S.N., C.H.), University of Oxford, Oxford, United Kingdom; and 1st Department of Cardiology, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece (T.K.).

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http://dx.doi.org/10.1161/CIRCIMAGING.115.004430DOI Listing
March 2016

Relationship Between Left Ventricular Structural and Metabolic Remodeling in Type 2 Diabetes.

Diabetes 2016 Jan 5;65(1):44-52. Epub 2015 Oct 5.

Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/db15-0627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890658PMC
January 2016

An Ester of β-Hydroxybutyrate Regulates Cholesterol Biosynthesis in Rats and a Cholesterol Biomarker in Humans.

Lipids 2015 Dec 26;50(12):1185-93. Epub 2015 Oct 26.

Laboratory of Metabolic Control, National Institute of Alcohol Abuse and Alcoholism, 5625 Fishers Ln 1S22, Rockville, MD, 20852, USA.

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http://dx.doi.org/10.1007/s11745-015-4085-xDOI Listing
December 2015

No Evidence of Myocardial Oxygen Deprivation in Nonischemic Heart Failure.

Circ Heart Fail 2015 Nov 2;8(6):1088-93. Epub 2015 Sep 2.

From the Division of Cardiovascular Medicine, Radcliffe Department of Medicine (S.D., O.J.R., M.M., M.R., E.S., H.W., H.A., T.D.K., S.N.) and Department of Physiology, Anatomy, and Genetics (C.J.H., L.E.C., K.C.), Oxford University, Oxford, United Kingdom.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.002169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645953PMC
November 2015

Detection of UCP1 protein and measurements of dependent GDP-sensitive proton leak in non-phosphorylating thymus mitochondria.

Methods Mol Biol 2015 ;1241:123-35

School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Pearse Street, Dublin 2, Ireland.

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http://link.springer.com/10.1007/978-1-4939-1875-1_11
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http://dx.doi.org/10.1007/978-1-4939-1875-1_11DOI Listing
June 2015

In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy.

Cardiovasc Res 2015 May 5;106(2):249-60. Epub 2015 Mar 5.

Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford OX1 3PT, UK

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http://dx.doi.org/10.1093/cvr/cvv101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400188PMC
May 2015

Varying degrees of ventricular unloading in the heterotopic rat heart transplant model demonstrated by magnetic resonance imaging.

Int J Biomed Sci 2014 Dec;10(4):223-8

Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, South Parks Road, Oxford OX1 3PT, U.K.;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289694PMC
December 2014

Investigating mitochondrial metabolism in contracting HL-1 cardiomyocytes following hypoxia and pharmacological HIF activation identifies HIF-dependent and independent mechanisms of regulation.

J Cardiovasc Pharmacol Ther 2014 Nov 7;19(6):574-85. Epub 2014 Mar 7.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, England, United Kingdom

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http://dx.doi.org/10.1177/1074248414524480DOI Listing
November 2014

Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy.

Circ Cardiovasc Imaging 2014 Nov 8;7(6):895-904. Epub 2014 Sep 8.

Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom (M.S.D., H.J.A., C.A.C., G.K.R., K.C., L.C.H., D.J.T.); Centre for Advanced Biomedical Imaging, University College London, London, United Kingdom (D.J.S.); and Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom (J.A.W., J.L.G.).

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http://heart.bmj.com/content/99/suppl_2/A118.1.full.pdf
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http://circimaging.ahajournals.org/cgi/doi/10.1161/CIRCIMAGI
Publisher Site
http://dx.doi.org/10.1161/CIRCIMAGING.114.001857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450075PMC
November 2014

Acute nutritional ketosis: implications for exercise performance and metabolism.

Extrem Physiol Med 2014 29;3:17. Epub 2014 Oct 29.

Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford OX1 3PT, UK.

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http://dx.doi.org/10.1186/2046-7648-3-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212585PMC
November 2014

HIV is an independent predictor of aortic stiffness.

J Cardiovasc Magn Reson 2014 Aug 16;16:57. Epub 2014 Aug 16.

Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.

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http://dx.doi.org/10.1186/s12968-014-0057-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422254PMC
August 2014

Hyperpolarized butyrate: a metabolic probe of short chain fatty acid metabolism in the heart.

Magn Reson Med 2014 May 24;71(5):1663-9. Epub 2013 Jun 24.

Cardiac Metabolism Research Group, Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/mrm.24849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238803PMC
May 2014

Murine cardiosphere-derived cells are impaired by age but not by cardiac dystrophic dysfunction.

Stem Cells Dev 2014 May 31;23(9):1027-36. Epub 2014 Jan 31.

1 Cardiac Metabolism Research Group, Department of Physiology, Anatomy, and Genetics, University of Oxford , Oxford, United Kingdom .

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http://dx.doi.org/10.1089/scd.2013.0388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996995PMC
May 2014

Effect of isoproterenol on myocardial perfusion, function, energy metabolism and nitric oxide pathway in the rat heart - a longitudinal MR study.

NMR Biomed 2014 May 20;27(5):529-38. Epub 2014 Feb 20.

Aix-Marseille Université UMR CNRS n°7339, Centre de Résonance Magnétique Biologique et Médicale (CRMBM), Faculté de Médecine, Marseille, France.

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http://doi.wiley.com/10.1002/nbm.3088
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http://dx.doi.org/10.1002/nbm.3088DOI Listing
May 2014

Stem cell-based therapy for ischemic heart disease.

Cell Transplant 2013 4;22(4):663-75. Epub 2012 Oct 4.

Cardiac Metabolism Research Group, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.3727/096368912X655109DOI Listing
January 2014

Metabolic imaging of acute and chronic infarction in the perfused rat heart using hyperpolarised [1-13C]pyruvate.

NMR Biomed 2013 Nov 14;26(11):1441-50. Epub 2013 Jun 14.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/nbm.2972DOI Listing
November 2013

Concentric left ventricular remodeling and aortic stiffness: a comparison of obesity and hypertension.

Int J Cardiol 2013 Sep 2;167(6):2989-94. Epub 2012 Oct 2.

Department of Cardiovascular Medicine, University of Oxford, UK.

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http://dx.doi.org/10.1016/j.ijcard.2012.08.049DOI Listing
September 2013

Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin.

Cardiovasc Diabetol 2013 Sep 24;12:136. Epub 2013 Sep 24.

Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, OX1 3PT, Oxford, UK.

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http://dx.doi.org/10.1186/1475-2840-12-136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849358PMC
September 2013

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.

Neurobiol Aging 2013 Jun 29;34(6):1530-9. Epub 2012 Dec 29.

Laboratory of Metabolic Control, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619192PMC
June 2013

Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial.

ACS Nano 2013 Apr 8;7(4):3362-72. Epub 2013 Mar 8.

CNC, Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1021/nn400171wDOI Listing
April 2013

Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics.

Proc Natl Acad Sci U S A 2013 Mar 19;110(10):E958-67. Epub 2013 Feb 19.

Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1213471110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593844PMC
March 2013

Human hippocampal energy metabolism is impaired during cognitive activity in a lipid infusion model of insulin resistance.

Brain Behav 2013 Mar 15;3(2):134-44. Epub 2013 Feb 15.

Cardiac Metabolism Research Group Department of Physiology, Anatomy and Genetics, University of Oxford Oxford, United Kingdom ; Oxford Centre for Clinical Magnetic Resonance Research (OCMR), University of Oxford Oxford, United Kingdom ; Oxford Project to Investigate Memory and Ageing (OPTIMA) Nuffield Department of Medicine, University of Oxford Oxford, United Kingdom.

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http://dx.doi.org/10.1002/brb3.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607154PMC
March 2013

Lack of activation of UCP1 in isolated brown adipose tissue mitochondria by glucose-O-ω-modified saturated fatty acids of various chain lengths.

J Chem Biol 2013 Mar 27;6(3):121-33. Epub 2013 Mar 27.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Pearse Street, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/s12154-013-0093-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691397PMC
March 2013

In vivo mouse cardiac hyperpolarized magnetic resonance spectroscopy.

J Cardiovasc Magn Reson 2013 Feb 18;15:19. Epub 2013 Feb 18.

Cardiac Metabolism Research Group, Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1186/1532-429X-15-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599631PMC
February 2013

Uncoupling protein 1 dependent reactive oxygen species production by thymus mitochondria.

Int J Biochem Cell Biol 2013 Jan 2;45(1):81-9. Epub 2012 Oct 2.

School of Biochemistry and Immunology, Trinity Institute of Biomedical Science, Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1016/j.biocel.2012.09.023DOI Listing
January 2013

A role for ubiquitinylation and the cytosolic proteasome in turnover of mitochondrial uncoupling protein 1 (UCP1).

Biochim Biophys Acta 2012 Oct 16;1817(10):1759-67. Epub 2012 Apr 16.

School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland.

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https://linkinghub.elsevier.com/retrieve/pii/S00052728120011
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http://dx.doi.org/10.1016/j.bbabio.2012.03.035DOI Listing
October 2012

MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas.

Cancer Res 2012 Oct 21;72(19):5060-8. Epub 2012 Aug 21.

Academic Endocrine Unit, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Headington, Oxford, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463502PMC
October 2012

In vivo alterations in cardiac metabolism and function in the spontaneously hypertensive rat heart.

Cardiovasc Res 2012 Jul 16;95(1):69-76. Epub 2012 May 16.

Department of Physiology, Anatomy and Genetics, Sherrington Building, University of Oxford, Parks Road, Oxford, UK.

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http://dx.doi.org/10.1093/cvr/cvs164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617603PMC
July 2012

Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet.

FASEB J 2012 Jun 23;26(6):2351-62. Epub 2012 Feb 23.

Laboratory of Metabolic Control, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland 20852, USA.

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http://dx.doi.org/10.1096/fj.11-200410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360149PMC
June 2012

In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy.

PLoS One 2012 3;7(1):e28569. Epub 2012 Jan 3.

Cardiac Metabolism Research Group, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028569PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250389PMC
May 2012

Increasing plasma free fatty acids in healthy subjects induces aortic distensibility changes seen in obesity.

Circ Cardiovasc Imaging 2012 May 5;5(3):367-75. Epub 2012 Apr 5.

University of Oxford Centre for Clinical Magnetic Resonance Research and the Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.111.9718
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http://dx.doi.org/10.1161/CIRCIMAGING.111.971804DOI Listing
May 2012

Metabolic adaptation to chronic hypoxia in cardiac mitochondria.

Basic Res Cardiol 2012 May 27;107(3):268. Epub 2012 Apr 27.

Cardiac Metabolism Research Group, Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford, OX1 3PT, UK.

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http://dx.doi.org/10.1007/s00395-012-0268-2DOI Listing
May 2012

Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors.

Mol Biol Rep 2012 Apr 9;39(4):4857-67. Epub 2011 Nov 9.

Cardiac Metabolism Research Group, Department of Physiology, Anatomy & Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford, OX1 3PT, UK.

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http://dx.doi.org/10.1007/s11033-011-1281-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294216PMC
April 2012

Efficient differentiation of human induced pluripotent stem cells generates cardiac cells that provide protection following myocardial infarction in the rat.

Stem Cells Dev 2012 Apr 15;21(6):977-86. Epub 2012 Feb 15.

Stem Cell Research Laboratory, NHS Blood and Transplant, John Radcliffe Hospital, Headington, Oxford, United Kingdom.

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https://www.liebertpub.com/doi/10.1089/scd.2011.0075
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http://dx.doi.org/10.1089/scd.2011.0075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315757PMC
April 2012

Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest.

FASEB J 2012 Apr 20;26(4):1431-41. Epub 2011 Dec 20.

Centre for Altitude, Space, and Extreme Environment Medicine, University College London (UCL) Institute of Child Health, University College London, London, UK.

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http://dx.doi.org/10.1096/fj.11-197772DOI Listing
April 2012

Effects of catecholamine stress on diastolic function and myocardial energetics in obesity.

Circulation 2012 Mar 24;125(12):1511-9. Epub 2012 Feb 24.

Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.069518DOI Listing
March 2012

Changes in cardiac substrate transporters and metabolic proteins mirror the metabolic shift in patients with aortic stenosis.

PLoS One 2011 18;6(10):e26326. Epub 2011 Oct 18.

Cardiac Metabolism Research Group, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026326PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196577PMC
February 2012

Myocardial substrate metabolism in heart disease.

Front Biosci (Schol Ed) 2012 Jan 1;4:556-80. Epub 2012 Jan 1.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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January 2012

Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1-13C]pyruvate.

NMR Biomed 2011 Oct 8;24(8):980-987. Epub 2011 Mar 8.

Cardiac Metabolism Research Group, Department of Physiology, Anatomy & Genetics, University of Oxford.

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http://doi.wiley.com/10.1002/nbm.1668
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http://dx.doi.org/10.1002/nbm.1668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604660PMC
October 2011

Chasing the reflected wave back into the heart: a new hypothesis while the jury is still out.

Vasc Health Risk Manag 2011 8;7:365-73. Epub 2011 Jun 8.

Department of Physiology, Anatomy, and Genetics, University of Oxford, UK.

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http://dx.doi.org/10.2147/VHRM.S20845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119594PMC
October 2011

Hyperpolarized magnetic resonance: a novel technique for the in vivo assessment of cardiovascular disease.

Circulation 2011 Oct;124(14):1580-94

Department of Physiology, Anatomy, and Genetics, Sherrington Bldg, University of Oxford, Parks Rd, Oxford, UK OX1 3PT.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.111.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.024919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189851PMC
October 2011

Normobaric hypoxia impairs human cardiac energetics.

FASEB J 2011 Sep 6;25(9):3130-5. Epub 2011 Jun 6.

Department of Physiology, Anatomy and Genetics, The University of Oxford, Oxford OX1 3PT, UK.

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http://dx.doi.org/10.1096/fj.11-183426DOI Listing
September 2011

Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats.

Nutr Metab (Lond) 2011 Aug 1;8:55. Epub 2011 Aug 1.

Department of Physiology, Anatomy & Genetics, University of Oxford, Parks Rd, Oxford, OX1 3PT, UK.

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http://dx.doi.org/10.1186/1743-7075-8-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168416PMC
August 2011

Details of left ventricular remodeling and the mechanism of paradoxical ventricular septal motion after coronary artery bypass graft surgery.

J Invasive Cardiol 2011 Jul;23(7):276-82

Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, United Kingdom.

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July 2011