Publications by authors named "Khalid A El Sayed"

95Publications

Olive Oil Lignan (+)-Acetoxypinoresinol Peripheral Motor and Neuronal Protection against the Tremorgenic Mycotoxin Penitrem A Toxicity STAT1 Pathway.

ACS Chem Neurosci 2020 11 13;11(21):3575-3589. Epub 2020 Oct 13.

School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, Louisiana 71201, United States.

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November 2020

(-)-Oleocanthal as a Dual c-MET-COX2 Inhibitor for the Control of Lung Cancer.

Nutrients 2020 Jun 11;12(6). Epub 2020 Jun 11.

School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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June 2020

Pseurotin A as a novel suppressor of hormone dependent breast cancer progression and recurrence by inhibiting PCSK9 secretion and interaction with LDL receptor.

Pharmacol Res 2020 08 11;158:104847. Epub 2020 May 11.

School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA, 71201, USA. Electronic address:

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August 2020

Novel olive oil phenolic (-)-oleocanthal (+)-xylitol-based solid dispersion formulations with potent oral anti-breast cancer activities.

Int J Pharm 2019 Oct 5;569:118596. Epub 2019 Aug 5.

School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, United States. Electronic address:

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October 2019

(-)-Oleocanthal Prevents Breast Cancer Locoregional Recurrence After Primary Tumor Surgical Excision and Neoadjuvant Targeted Therapy in Orthotopic Nude Mouse Models.

Cancers (Basel) 2019 May 8;11(5). Epub 2019 May 8.

School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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May 2019

(-)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo.

Nutrients 2019 Feb 15;11(2). Epub 2019 Feb 15.

School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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February 2019

13 -Oxophorbine protopheophorbide A from Ziziphus lotus as a novel mesenchymal-epithelial transition factor receptor inhibitory lead for the control of breast tumor growth in vitro and in vivo.

Mol Carcinog 2018 11 18;57(11):1507-1524. Epub 2018 Jul 18.

Institut Pasteur de Tunis, LR11IPT04, LR16IPT04 Laboratoire d'Epidémiologie Moléculaire et Pathologie Expérimentale Appliquée Aux Maladies Infectieuses, Tunis, Tunisia.

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November 2018

The Maxi-K (BK) Channel Antagonist Penitrem A as a Novel Breast Cancer-Targeted Therapeutic.

Mar Drugs 2018 May 11;16(5). Epub 2018 May 11.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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May 2018

Rutin as A Novel c-Met Inhibitory Lead for The Control of Triple Negative Breast Malignancies.

Nutr Cancer 2017 Nov-Dec;69(8):1256-1271. Epub 2017 Oct 30.

a Department of Basic Pharmaceutical Sciences, School of Pharmacy , University of Louisiana at Monroe , Monroe , Louisiana.

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August 2018

Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignancies.

Bioorg Med Chem 2017 12 27;25(24):6297-6312. Epub 2017 Sep 27.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, USA. Electronic address:

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December 2017

The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment.

Eur J Pharmacol 2017 Sep 15;810:100-111. Epub 2017 Jun 15.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, USA.

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September 2017

The tobacco cembranoid (1S,2E,4S,7E,11E)-2,7,11-cembratriene-4,6-diol as a novel angiogenesis inhibitory lead for the control of breast malignancies.

Bioorg Med Chem 2017 08 20;25(15):3911-3921. Epub 2017 May 20.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, USA. Electronic address:

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August 2017

Oleocanthal ameliorates amyloid-β oligomers' toxicity on astrocytes and neuronal cells: In vitro studies.

Neuroscience 2017 06 7;352:204-215. Epub 2017 Apr 7.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA, USA. Electronic address:

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June 2017

Usnic Acid Benzylidene Analogues as Potent Mechanistic Target of Rapamycin Inhibitors for the Control of Breast Malignancies.

J Nat Prod 2017 04 28;80(4):932-952. Epub 2017 Feb 28.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe , Monroe, Louisiana 71209, United States.

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April 2017

The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR.

Biochem Pharmacol 2017 Feb 8;126:51-68. Epub 2016 Dec 8.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, United States. Electronic address:

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February 2017

Astaxanthin and Docosahexaenoic Acid Reverse the Toxicity of the Maxi-K (BK) Channel Antagonist Mycotoxin Penitrem A.

Mar Drugs 2016 Nov 9;14(11). Epub 2016 Nov 9.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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November 2016

(1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol semisynthetic analogs as novel c-Met inhibitors for the control of c-Met-dependent breast malignancies.

Bioorg Med Chem 2016 11 13;24(22):5748-5761. Epub 2016 Sep 13.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA. Electronic address:

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November 2016

Cancer control potential of marine natural product scaffolds through inhibition of tumor cell migration and invasion.

Drug Discov Today 2016 11 6;21(11):1745-1760. Epub 2016 Jul 6.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, The University of Louisiana at Monroe, Monroe, LA 71201, USA.

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November 2016

Novel c-Met inhibitory olive secoiridoid semisynthetic analogs for the control of invasive breast cancer.

Eur J Med Chem 2016 08 8;118:299-315. Epub 2016 Aug 8.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA, 71201, USA. Electronic address:

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August 2016

The oleocanthal-based homovanillyl sinapate as a novel c-Met inhibitor.

Oncotarget 2016 May;7(22):32247-73

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, USA.

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May 2016

Discovery of Novel Antiangiogenic Marine Natural Product Scaffolds.

Mar Drugs 2016 Mar 11;14(3). Epub 2016 Mar 11.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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March 2016

Norstictic Acid Inhibits Breast Cancer Cell Proliferation, Migration, Invasion, and In Vivo Invasive Growth Through Targeting C-Met.

Phytother Res 2016 Apr 6;30(4):557-66. Epub 2016 Jan 6.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, 71201, USA.

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April 2016

The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation, migration and invasion.

Bioorg Med Chem 2016 Jan 28;24(2):113-22. Epub 2015 Nov 28.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, United States. Electronic address:

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January 2016

Isothiocyanatostilbenes as novel c-Met inhibitors.

Oncotarget 2015 Dec;6(38):41180-93

Louisiana State University Health Sciences Center - Shreveport, Shreveport, LA, USA.

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December 2015

Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier model.

ACS Chem Neurosci 2015 Nov 16;6(11):1849-59. Epub 2015 Sep 16.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe , Monroe, Louisiana 71201, United States.

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November 2015

Olive Oil-derived Oleocanthal as Potent Inhibitor of Mammalian Target of Rapamycin: Biological Evaluation and Molecular Modeling Studies.

Phytother Res 2015 Nov 7;29(11):1776-82. Epub 2015 Aug 7.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, USA.

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November 2015

PEGylated γ-tocotrienol isomer of vitamin E: Synthesis, characterization, in vitro cytotoxicity, and oral bioavailability.

Eur J Pharm Biopharm 2015 Oct 30;96:185-95. Epub 2015 Jul 30.

College of Health and Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA, USA; College of Pharmacy, Taipei Medical University, Taipei, Taiwan. Electronic address:

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October 2015

Esters of the marine-derived triterpene sipholenol A reverse P-GP-mediated drug resistance.

Mar Drugs 2015 Apr 14;13(4):2267-86. Epub 2015 Apr 14.

Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA.

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April 2015

Araguspongine C induces autophagic death in breast cancer cells through suppression of c-Met and HER2 receptor tyrosine kinase signaling.

Mar Drugs 2015 Jan 8;13(1):288-311. Epub 2015 Jan 8.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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January 2015

3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells.

Eur J Pharmacol 2014 Oct 18;740:209-17. Epub 2014 Jul 18.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA. Electronic address:

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October 2014

Discovery, optimization, and pharmacophore modeling of oleanolic acid and analogues as breast cancer cell migration and invasion inhibitors through targeting Brk/Paxillin/Rac1 axis.

Chem Biol Drug Des 2015 Feb 16;85(2):231-43. Epub 2014 Jul 16.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA, 71201, USA; Department of Pharmacognosy, Faculty of Pharmacy, Helwan University, Helwan, Cairo, 11795, Egypt.

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February 2015

The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling.

Mar Drugs 2014 Apr 14;12(4):2282-304. Epub 2014 Apr 14.

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana, 1800 Bienville Drive, Monroe, LA 71201, USA.

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April 2014

Laboratory exercises to teach clinically relevant chemistry of antibiotics.

Am J Pharm Educ 2014 Mar;78(2):37

School of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana.

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March 2014

Optimization, pharmacophore modeling and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors.

Eur J Med Chem 2014 Feb 12;73:310-24. Epub 2013 Dec 12.

Department of Basic Pharmaceutical Sciences of College of Pharmacy, University of Louisiana at Monroe, USA. Electronic address:

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February 2014

Indole diterpene alkaloids as novel inhibitors of the Wnt/β-catenin pathway in breast cancer cells.

Eur J Med Chem 2013 8;70:594-606. Epub 2013 Oct 8.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, USA.

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September 2014

New alkaloids from Pancratium maritimum.

Planta Med 2013 Oct 22;79(15):1480-4. Epub 2013 Aug 22.

Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.

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October 2013

Selective growth inhibition of human malignant melanoma cells by syringic acid-derived proteasome inhibitors.

Cancer Cell Int 2013 Aug 19;13(1):82. Epub 2013 Aug 19.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Health Sciences Center, Kuwait University, Safat 13110, Kuwait.

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August 2013

Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies.

ACS Chem Neurosci 2013 Jun 25;4(6):973-82. Epub 2013 Feb 25.

Department of Basic Pharmaceutical Science, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, Louisiana 7120, United States.

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June 2013

Optimization of marine triterpene sipholenols as inhibitors of breast cancer migration and invasion.

ChemMedChem 2013 Mar 12;8(3):497-510. Epub 2013 Feb 12.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Dr., Monroe, LA 71201, USA.

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March 2013

Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer.

Bioorg Med Chem 2013 Apr 9;21(7):2117-27. Epub 2013 Jan 9.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, United States.

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April 2013

Optimization of tocotrienols as antiproliferative and antimigratory leads.

Eur J Med Chem 2013 Jan 23;59:329-41. Epub 2012 Nov 23.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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January 2013

Subereamolline A as a potent breast cancer migration, invasion and proliferation inhibitor and bioactive dibrominated alkaloids from the Red Sea sponge Pseudoceratina arabica.

Mar Drugs 2012 Nov 8;10(11):2492-508. Epub 2012 Nov 8.

Natural Products Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Kingdom of Saudi Arabia.

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November 2012

Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products.

Food Chem Toxicol 2011 Nov 10;49(11):2765-72. Epub 2011 Aug 10.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, United States.

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November 2011

Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors.

Bioorg Med Chem 2011 Aug 28;19(16):4928-34. Epub 2011 Jun 28.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, USA.

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August 2011

Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors.

Eur J Med Chem 2011 Apr 28;46(4):1122-30. Epub 2011 Jan 28.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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April 2011

(-)-Oleocanthal as a c-Met inhibitor for the control of metastatic breast and prostate cancers.

Planta Med 2011 Jul 15;77(10):1013-9. Epub 2011 Feb 15.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana 71201, USA.

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July 2011

Methods for evaluation of structural and biological properties of antiinvasive natural products.

Methods Mol Biol 2011 ;716:55-71

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA, USA.

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May 2011

Synthesis of fluorescent analogues of the anticancer natural products 4-hydroxyphenylmethylene hydantoin and delta-tocotrienol.

Nat Prod Commun 2010 Oct;5(10):1623-6

Department of Basic Pharmaceutical Sciences, College of Pharmacy, 1800 Bienville Drive, University of Louisiana at Monroe, Monroe, Louisiana 71201, USA.

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October 2010

Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand- and structure-based virtual screening.

J Med Chem 2010 Dec 17;53(24):8534-45. Epub 2010 Nov 17.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana 71201, USA.

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December 2010

Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids.

Planta Med 2011 Mar 3;77(5):467-76. Epub 2010 Nov 3.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, USA.

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March 2011

Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors.

Bioorg Med Chem 2010 Nov 19;18(22):8066-75. Epub 2010 Sep 19.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, United States.

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November 2010

Design, synthesis, and biological evaluation of dibromotyrosine analogues inspired by marine natural products as inhibitors of human prostate cancer proliferation, invasion, and migration.

Bioorg Med Chem 2010 Nov 29;18(21):7446-57. Epub 2010 Sep 29.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, LA 71201, USA.

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November 2010

Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA approach and QSAR analysis.

Eur J Med Chem 2010 Nov 8;45(11):5397-405. Epub 2010 Sep 8.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Drive, Monroe, Louisiana 71201, USA.

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November 2010

The value of tocotrienols in the prevention and treatment of cancer.

J Am Coll Nutr 2010 Jun;29(3 Suppl):324S-333S

College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71209, USA.

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June 2010

3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches.

Eur J Med Chem 2010 Sep 12;45(9):3662-8. Epub 2010 May 12.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 1800 Bienville Dr. Monroe, LA 71201, USA.

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September 2010

Manzamine A as a novel inhibitor of herpes simplex virus type-1 replication in cultured corneal cells.

Planta Med 2011 Jan 19;77(1):46-51. Epub 2010 Jul 19.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, The University of Louisiana at Monroe, Monroe, LA 71201, USA.

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January 2011

Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure-activity relationship and molecular modeling studies.

ChemMedChem 2010 Feb;5(2):274-85

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, USA.

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February 2010

Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors.

Bioorg Med Chem 2010 Jan 11;18(2):496-507. Epub 2009 Dec 11.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 700 University Avenue, Monroe, LA 71209, USA.

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January 2010

Design and preliminary structure-activity relationship of redox-silent semisynthetic tocotrienol analogues as inhibitors for breast cancer proliferation and invasion.

Bioorg Med Chem 2010 Jan 27;18(2):755-68. Epub 2009 Nov 27.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, United States.

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January 2010

Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors.

J Nat Prod 2009 Sep;72(9):1643-50

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, USA.

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September 2009

The marine natural-derived inhibitors of glycogen synthase kinase-3beta phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling.

Bioorg Med Chem 2009 Aug 27;17(16):6032-9. Epub 2009 Jun 27.

Department of Basic Pharmaceutical Sciences, University of Louisiana at Monroe, LA 71201, United States.

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August 2009

Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products.

Bioorg Med Chem 2009 Feb 29;17(4):1731-8. Epub 2008 Dec 29.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71201, USA.

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February 2009

Antiproliferative triterpenes from Melaleuca ericifolia.

J Nat Prod 2008 Oct 1;71(10):1787-90. Epub 2008 Oct 1.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 700 University Avenue, Monroe, Louisiana 71209, USA.

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October 2008

Sinulodurins A and B, antiproliferative and anti-invasive diterpenes from the soft coral Sinularia dura.

J Nat Prod 2008 Aug 17;71(8):1468-71. Epub 2008 Jul 17.

National Center for Natural Products Research, University of Mississippi, University, Mississippi 38677-1848, USA.

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August 2008

Biocatalytic and semisynthetic optimization of the anti-invasive tobacco (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol.

Bioorg Med Chem 2008 Mar 3;16(6):2886-93. Epub 2008 Jan 3.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 700 University Avenue, Monroe, LA 71209, USA.

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March 2008

Semisynthetic and biotransformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol.

J Nat Prod 2008 Jan 5;71(1):117-22. Epub 2008 Jan 5.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe 71209, USA.

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January 2008

Biocatalytic and semisynthetic studies of the anticancer tobacco cembranoids.

Expert Opin Investig Drugs 2007 Jun;16(6):877-87

University of Louisiana at Monroe, Department of Basic Pharmaceutical Sciences, College of Pharmacy, Monroe, Louisiana 71209, USA.

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June 2007

Reversal of P-glycoprotein-mediated multidrug resistance by sipholane triterpenoids.

J Nat Prod 2007 Jun 9;70(6):928-31. Epub 2007 May 9.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana 71209, USA.

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June 2007

Biocatalysis of the anticancer sipholane triterpenoids.

Planta Med 2007 Jun 7;73(6):591-6. Epub 2007 May 7.

College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana, USA.

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June 2007

Biocatalytic and antimetastatic studies of the marine cembranoids sarcophine and 2-epi-16-deoxysarcophine.

J Nat Prod 2006 Jul;69(7):1010-3

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, 700 University Avenue, Monroe, Louisiana 71209, USA.

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July 2006

Bioactive natural and semisynthetic latrunculins.

J Nat Prod 2006 Feb;69(2):219-23

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Louisiana 71209, USA.

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February 2006

Bioactive rearranged and halogenated semisynthetic derivatives of the marine natural product sarcophine.

J Nat Prod 2004 Dec;67(12):2017-23

Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, 700 University Avenue, Monroe, Louisiana 71209, USA.

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December 2004

Limonoids from Citrus reticulata.

Z Naturforsch C J Biosci 2003 Mar-Apr;58(3-4):165-70

Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.

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June 2003

Marine natural products as prototype agrochemical agents.

J Agric Food Chem 2003 Apr;51(8):2246-52

Department of Pharmacognosy and National Center for the Development of Natural Products, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, USA.

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April 2003

Microbial transformation of rubijervine.

Chem Pharm Bull (Tokyo) 2002 Nov;50(11):1427-9

Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, Egypt.

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November 2002

Structurally Novel Bioconversion Products of the Marine Natural Product Sarcophine Effectively Inhibit JB6 Cell Transformation.

J Org Chem 1998 Oct;63(21):7449-7455

Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, 833 South Wood Street, Chicago, Illinois 60612-7231.

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October 1998