Publications by authors named "Kezhong Wang"

4 Publications

  • Page 1 of 1

Platinized graphene fiber electrodes uncover direct spleen-vagus communication.

Commun Biol 2021 09 17;4(1):1097. Epub 2021 Sep 17.

Biomedical Engineering and Biomedical Sciences, University of Houston, Health 2, 4849 Calhoun Rd., Room 6014, Houston, TX, 77204-6064, USA.

Neural interfacing nerve fascicles along the splenic neurovascular plexus (SNVP) is needed to better understand the spleen physiology, and for selective neuromodulation of this major organ. However, their small size and anatomical location have proven to be a significant challenge. Here, we use a reduced liquid crystalline graphene oxide (rGO) fiber coated with platinum (Pt) as a super-flexible suture-like electrode to interface multiple SNVP. The Pt-rGO fibers work as a handover knot electrodes over the small SNVP, allowing sensitive recording from four splenic nerve terminal branches (SN 1-4), to uncover differential activity and axon composition among them. Here, the asymmetric defasciculation of the SN branches is revealed by electron microscopy, and the functional compartmentalization in spleen innervation is evidenced in response to hypoxia and pharmacological modulation of mean arterial pressure. We demonstrate that electrical stimulation of cervical and sub-diaphragmatic vagus nerve (VN), evokes activity in a subset of SN terminal branches, providing evidence for a direct VN control over the spleen. This notion is supported by adenoviral tract-tracing of SN branches, revealing an unconventional direct brain-spleen projection. High-performance Pt-rGO fiber electrodes, may be used for the fine neural modulation of other small neurovascular plexus at the point of entry of major organs as a bioelectronic medical alternative.
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http://dx.doi.org/10.1038/s42003-021-02628-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448843PMC
September 2021

A Self-Assembled CO Reduction Electrocatalyst: Posy-Bouquet-Shaped Gold-Polyaniline Core-Shell Nanocomposite.

ChemSusChem 2020 Sep 10;13(18):5023-5030. Epub 2020 Aug 10.

ARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, University of Wollongong, North Wollongong, NSW, 2500, Australia.

Here it was demonstrated that the decoration of gold (Au) with polyaniline is an effective approach in increasing its electrocatalytic reduction of CO to CO. The core-shell-structured gold-polyaniline (Au-PANI) nanocomposite delivered a CO -to-CO conversion efficiency of 85 % with a high current density of 11.6 mA cm . The polyaniline shell facilitated CO adsorption, and the subsequent formation of reaction intermediates on the gold core contributed to the high efficiency observed.
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http://dx.doi.org/10.1002/cssc.202001248DOI Listing
September 2020

Scalable Solution Processing MoS Powders with Liquid Crystalline Graphene Oxide for Flexible Freestanding Films with High Areal Lithium Storage Capacity.

ACS Appl Mater Interfaces 2019 Dec 3;11(50):46746-46755. Epub 2019 Dec 3.

ARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility , University of Wollongong , North Wollongong , New South Wales 2500 , Australia.

Freestanding flexible electrodes with high areal mass loading are required for the development of flexible high-performance lithium-ion batteries (LIBs). Currently they face the challenge of low mass loading due to the limited concentrations attainable in processable dispersions. Here, we report a simple low-temperature hydrothermal route to fabricate flexible layered molybdenum disulfide (MoS)/reduced graphene oxide (MSG) films offering high areal capacity and good lithium storage performance. This is achieved using a self-assembly process facilitated by the use of liquid crystalline graphene oxide (LCGO) and commercial MoS powders at a low temperature of 70 °C. The amphiphilic properties of ultralarge LCGO nanosheets facilitates the processability of large-size MoS powders, which is otherwise nondispersible in water. The resultant film with an areal mass of 8.2 mg cm delivers a high areal capacity of 5.80 mAh cm (706 mAh g) at 0.1 A g. This simple method can be adapted to similar nondispersible commercial battery materials for films fabrication or production of more complicated constructs via advanced fabrication technologies.
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http://dx.doi.org/10.1021/acsami.9b15371DOI Listing
December 2019

High-Performance Graphene-Fiber-Based Neural Recording Microelectrodes.

Adv Mater 2019 Apr 25;31(15):e1805867. Epub 2019 Feb 25.

Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, University of Wollongong, Wollongong, NSW, 2522, Australia.

Fabrication of flexible and free-standing graphene-fiber- (GF-) based microelectrode arrays with a thin platinum coating, acting as a current collector, results in a structure with low impedance, high surface area, and excellent electrochemical properties. This modification results in a strong synergistic effect between these two constituents leading to a robust and superior hybrid material with better performance than either graphene electrodes or Pt electrodes. The low impedance and porous structure of the GF results in an unrivalled charge injection capacity of 10.34 mC cm with the ability to record and detect neuronal activity. Furthermore, the thin Pt layer transfers the collected signals along the microelectrode efficiently. In vivo studies show that microelectrodes implanted in the rat cerebral cortex can detect neuronal activity with remarkably high signal-to-noise ratio (SNR) of 9.2 dB in an area as small as an individual neuron.
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http://dx.doi.org/10.1002/adma.201805867DOI Listing
April 2019
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