Publications by authors named "Keyur P Patel"

100Publications

Evaluation of Somatic Hypermutation Status in Chronic Lymphocytic Leukemia (CLL) in the Era of Next Generation Sequencing.

Front Cell Dev Biol 2020 19;8:357. Epub 2020 May 19.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.3389/fcell.2020.00357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248390PMC
May 2020

Comparison of therapy-related myelodysplastic syndrome with ring sideroblasts and de novo myelodysplastic syndrome with ring sideroblasts.

Leuk Res 2019 11 17;86:106227. Epub 2019 Sep 17.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.106227DOI Listing
November 2019

Novel Disease Risk Model for Patients with Acute Myeloid Leukemia Receiving Allogeneic Hematopoietic Cell Transplantation.

Biol Blood Marrow Transplant 2020 01 10;26(1):197-203. Epub 2019 Sep 10.

Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2019.09.006DOI Listing
January 2020

Successful lenalidomide treatment in high risk myelodysplastic syndrome with germline DDX41 mutation.

Am J Hematol 2020 02 29;95(2):227-229. Epub 2019 Aug 29.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/ajh.25610DOI Listing
February 2020

Clinical implications of cytogenetic heterogeneity in Philadelphia chromosome positive (Ph+) adult B cell acute lymphoblastic leukemia following tyrosine kinase inhibitors and chemotherapy regimens.

Leuk Res 2019 09 27;84:106176. Epub 2019 Jun 27.

Departments of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01452126193012
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http://dx.doi.org/10.1016/j.leukres.2019.106176DOI Listing
September 2019

Data on rearrangement-driven chromosomal aberrations in myeloid malignancies.

Data Brief 2019 Jun 23;24:104025. Epub 2019 May 23.

Department of Hematopathology, School of Health Professions, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.dib.2019.104025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545385PMC
June 2019

TP53 mutations are common in mantle cell lymphoma, including the indolent leukemic non-nodal variant.

Ann Diagn Pathol 2019 Aug 16;41:38-42. Epub 2019 May 16.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2019.05.004DOI Listing
August 2019

Deciphering the complexities of MECOM rearrangement-driven chromosomal aberrations.

Cancer Genet 2019 04 11;233-234:21-31. Epub 2019 Mar 11.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, United States.

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http://dx.doi.org/10.1016/j.cancergen.2019.03.002DOI Listing
April 2019

Unique Case of Myeloproliferative Neoplasm with Two Rare Clonal Abnormalities: Rare JAK2 Exon 12 Mutation and Rare e14a3 (b3a3) BCR/ABL Fusion Transcript.

Acta Haematol 2019 21;141(1):23-27. Epub 2018 Nov 21.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA,

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http://dx.doi.org/10.1159/000494427DOI Listing
September 2019

Challenges in next generation sequencing analysis of somatic mutations in transplant patients.

Cancer Genet 2018 10 10;226-227:17-22. Epub 2018 May 10.

Division of Pathology and Laboratory Medicine, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Pathology, University of Alabama at Birmingham, NP 3538, 619 19th Street S, Birmingham, AL 35249-7331, United States . Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22107762173039
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http://dx.doi.org/10.1016/j.cancergen.2018.04.119DOI Listing
October 2018

Clinicopathologic and molecular features in hairy cell leukemia-variant: single institutional experience.

Mod Pathol 2018 11 28;31(11):1717-1732. Epub 2018 Jun 28.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41379-018-0093-8DOI Listing
November 2018

The co-occurrence of driver mutations in chronic myeloproliferative neoplasms.

Ann Hematol 2018 Nov 27;97(11):2071-2080. Epub 2018 Jun 27.

Department of Leukemia, UT MD Anderson Cancer Center, 1515 Holcombe Blvd (Unit 428), Houston, TX, 77030, USA.

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http://link.springer.com/10.1007/s00277-018-3402-x
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http://dx.doi.org/10.1007/s00277-018-3402-xDOI Listing
November 2018

Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia.

J Clin Oncol 2018 06 27;36(18):1788-1797. Epub 2018 Apr 27.

Kiyomi Morita, Hagop M. Kantarjian, Feng Wang, Yuanqing Yan, Carlos Bueso-Ramos, Koji Sasaki, Ghayas C. Issa, Sa Wang, Jeffrey Jorgensen, Xingzhi Song, Jianhua Zhang, Samantha Tippen, Rebecca Thornton, Marcus Coyle, Latasha Little, Curtis Gumbs, Naveen Pemmaraju, Naval Daver, Courtney D. DiNardo, Marina Konopleva, Michael Andreeff, Farhad Ravandi, Jorge E. Cortes, Tapan Kadia, Elias Jabbour, Guillermo Garcia-Manero, Keyur P. Patel, P. Andrew Futreal, and Koichi Takahash, The University of Texas MD Anderson Cancer Center, Houston, TX; Kiyomi Morita, The University of Tokyo, Tokyo; and Koichi Takahashi, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1200/JCO.2017.77.6757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008108PMC
June 2018

Molecular Profile of Advanced Thyroid Carcinomas by Next-Generation Sequencing: Characterizing Tumors Beyond Diagnosis for Targeted Therapy.

Mol Cancer Ther 2018 07 25;17(7):1575-1584. Epub 2018 Apr 25.

Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0871DOI Listing
July 2018

Predictive Gene Signatures Determine Tumor Sensitivity to MDM2 Inhibition.

Cancer Res 2018 05 28;78(10):2721-2731. Epub 2018 Feb 28.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955838PMC
May 2018

Early Post-Transplant Minimal Residual Disease Assessment Improves Risk Stratification in Acute Myeloid Leukemia.

Biol Blood Marrow Transplant 2018 07 12;24(7):1514-1520. Epub 2018 Feb 12.

Department of Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2018.02.003DOI Listing
July 2018

Acquired amegakaryocytic thrombocytopenia and red cell aplasia in a patient with thymoma progressing to aplastic anemia successfully treated with allogenic stem cell transplantation.

Hematol Oncol Stem Cell Ther 2019 Jun 31;12(2):115-118. Epub 2018 Jan 31.

Section of Benign Hematology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.hemonc.2017.09.001DOI Listing
June 2019

Sensitive PCR-based monitoring and early detection of relapsed JAK2 V617F myelofibrosis following transplantation.

Br J Haematol 2018 12 19;183(5):831-835. Epub 2017 Dec 19.

Department of Stem Cell Transplantation and Cellular Therapy, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1111/bjh.15059DOI Listing
December 2018

Characterization of TP53 mutations in low-grade myelodysplastic syndromes and myelodysplastic syndromes with a non-complex karyotype.

Eur J Haematol 2017 Dec 20;99(6):536-543. Epub 2017 Oct 20.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://doi.wiley.com/10.1111/ejh.12971
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http://dx.doi.org/10.1111/ejh.12971DOI Listing
December 2017

Diagnostic, Prognostic, and Predictive Utility of Recurrent Somatic Mutations in Myeloid Neoplasms.

Clin Lymphoma Myeloma Leuk 2017 07;17S:S62-S74

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2017.02.015DOI Listing
July 2017

Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms.

Mod Pathol 2017 10 30;30(10):1338-1366. Epub 2017 Jun 30.

Department of Hematopathology, MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/modpathol.2017.58DOI Listing
October 2017

Mutually exclusive recurrent KRAS and MAP2K1 mutations in Rosai-Dorfman disease.

Mod Pathol 2017 10 30;30(10):1367-1377. Epub 2017 Jun 30.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/modpathol.2017.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837474PMC
October 2017

Mast cell leukemia (MCL): Clinico-pathologic and molecular features and survival outcome.

Leuk Res 2017 08 1;59:105-109. Epub 2017 Jun 1.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2017.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573652PMC
August 2017

Characterization of TP53 mutations in clonal cytopenia of undetermined significance.

Am J Hematol 2017 Aug 9;92(8):E175-E177. Epub 2017 Jun 9.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030.

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http://doi.wiley.com/10.1002/ajh.24786
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http://dx.doi.org/10.1002/ajh.24786DOI Listing
August 2017

Validation of quantitative PCR-based assays for detection of gene copy number aberrations in formalin-fixed, paraffin embedded solid tumor samples.

Cancer Genet 2017 04 20;212-213:24-31. Epub 2017 Mar 20.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2017.03.002DOI Listing
April 2017

Retrospective Analysis of Molecular and Immunohistochemical Characterization of 381 Primary Brain Tumors.

J Neuropathol Exp Neurol 2017 03;76(3):179-188

Department of Hematopathology, UT-MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1093/jnen/nlw119DOI Listing
March 2017

Immunophenotypic Shifts in Primary Cutaneous γδ T-Cell Lymphoma Suggest Antigenic Modulation: A Study of Sequential Biopsy Specimens.

Am J Surg Pathol 2017 Apr;41(4):431-445

Departments of *Hematopathology †Pathology ‡Dermatology ¶Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX §University of Missouri, Kansas City, MO ∥Departamento de Patologia, Universidad Peruana Cayetano Heredia, Lima, Peru.

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http://dx.doi.org/10.1097/PAS.0000000000000786DOI Listing
April 2017

A Targeted High-Throughput Next-Generation Sequencing Panel for Clinical Screening of Mutations, Gene Amplifications, and Fusions in Solid Tumors.

J Mol Diagn 2017 03 23;19(2):255-264. Epub 2016 Dec 23.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.09.011DOI Listing
March 2017

Coexistence of iAMP21 and fusion in an adolescent with B cell acute lymphoblastic leukemia: literature review of six additional cases.

Mol Cytogenet 2016 21;9:84. Epub 2016 Nov 21.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd. Unit 0350, Houston, TX 77030 USA ; Department of Pathology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 7-723, Chicago, IL 60611 USA.

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http://dx.doi.org/10.1186/s13039-016-0294-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117506PMC
November 2016

Acute erythroid leukemia with <20% bone marrow blasts is clinically and biologically similar to myelodysplastic syndrome with excess blasts.

Mod Pathol 2016 10 15;29(10):1221-31. Epub 2016 Jul 15.

Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2016.118DOI Listing
October 2016

How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments?

J Natl Compr Canc Netw 2016 06;14(6):787-92

Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston Texas

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http://dx.doi.org/10.6004/jnccn.2016.0079DOI Listing
June 2016

Clinical Validation of a CXCR4 Mutation Screening Assay for Waldenstrom Macroglobulinemia.

Clin Lymphoma Myeloma Leuk 2016 07 5;16(7):395-403.e1. Epub 2016 May 5.

Department of Hematopathology, The University of Texas, MD Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2016.04.014DOI Listing
July 2016