Kevin Y Yip

Horseshoe crab genomes reveal the evolution of genes and microRNAs after three rounds of whole genome duplication.

Commun Biol 2021 Jan 19;4(1):83. Epub 2021 Jan 19.

School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, China.

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January 2021

A general near-exact k-mer counting method with low memory consumption enables de novo assembly of 106× human sequence data in 2.7 hours.

Authors:

Christina Huan Shi Kevin Y Yip

Bioinformatics 2020 Dec;36(Supplement_2):i625-i633

Department of Computer Science and Engineering.

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December 2020

G9a Plays Distinct Roles in Maintaining DNA Methylation, Retrotransposon Silencing, and Chromatin Looping.

Authors:

Qinghong Jiang Julie Y J Ang Ah Young Lee Qin Cao Kelly Y Li Kevin Y Yip Danny C Y Leung

Cell Rep 2020 Oct;33(4):108315

Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China. Electronic address:

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October 2020

Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease.

Authors:

Alexander Xi Fu Kathy Nga-Chu Lui Clara Sze-Man Tang Ray Kit Ng Frank Pui-Ling Lai Sin-Ting Lau Zhixin Li Maria-Mercè Garcia-Barcelo Pak-Chung Sham Paul Kwong-Hang Tam Elly Sau-Wai Ngan Kevin Y Yip

Genome Res 2020 Nov 18;30(11):1618-1632. Epub 2020 Sep 18.

Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong.

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November 2020

Supervised enhancer prediction with epigenetic pattern recognition and targeted validation.

Nat Methods 2020 08 29;17(8):807-814. Epub 2020 Jul 29.

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.

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August 2020

Jellyfish genomes reveal distinct homeobox gene clusters and conservation of small RNA processing.

Authors:

Wenyan Nong Jianquan Cao Yiqian Li Zhe Qu Jin Sun Thomas Swale Ho Yin Yip Pei Yuan Qian Jian-Wen Qiu Hoi Shan Kwan William Bendena Stephen Tobe Ting Fung Chan Kevin Y Yip Ka Hou Chu Sai Ming Ngai Karl Yk Tsim Peter W H Holland Jerome H L Hui

Nat Commun 2020 06 19;11(1):3051. Epub 2020 Jun 19.

School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong.

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June 2020

Reply to 'Inflated performance measures in enhancer-promoter interaction-prediction methods'.

Authors:

Qin Cao Kevin Y Yip

Nat Genet 2019 08;51(8):1201-1202

Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.

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August 2019

OMMA enables population-scale analysis of complex genomic features and phylogenomic relationships from nanochannel-based optical maps.

Authors:

Alden King-Yung Leung Melissa Chun-Jiao Liu Le Li Yvonne Yuk-Yin Lai Catherine Chu Pui-Yan Kwok Pak-Leung Ho Kevin Y Yip Ting-Fung Chan

Gigascience 2019 07;8(7)

School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.

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July 2019

Shaping the nebulous enhancer in the era of high-throughput assays and genome editing.

Authors:

Edwin Yu-Kiu Ho Qin Cao Mengting Gu Ricky Wai-Lun Chan Qiong Wu Mark Gerstein Kevin Y Yip

Brief Bioinform 2020 05;21(3):836-850

Department of Biomedical Engineering.

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May 2020

Genome maps across 26 human populations reveal population-specific patterns of structural variation.

Nat Commun 2019 03 4;10(1):1025. Epub 2019 Mar 4.

Cardiovascular Research Institute, University of California-San Francisco, San Francisco, CA, 94143, USA.

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March 2019

New guidelines for DNA methylome studies regarding 5-hydroxymethylcytosine for understanding transcriptional regulation.

Authors:

Le Li Yuwei Gao Qiong Wu Alfred S L Cheng Kevin Y Yip

Genome Res 2019 04 19;29(4):543-553. Epub 2019 Feb 19.

Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.

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April 2019

Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming.

Nat Commun 2019 01 18;10(1):335. Epub 2019 Jan 18.

Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China.

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January 2019

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma.

Nat Commun 2018 11 7;9(1):4663. Epub 2018 Nov 7.

School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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November 2018

Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis.

Nucleic Acids Res 2018 09;46(17):8832-8847

School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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September 2018

Case Report: Exome sequencing reveals recurrent mutations and a loss-of-function mutation in a rare undifferentiated tongue sarcoma.

Authors:

Jason Y K Chan Peony Hiu Yan Poon Yong Zhang Cherrie W K Ng Wen Ying Piao Meng Ma Kevin Y Yip Amy B W Chan Vivian Wai Yan Lui

F1000Res 2018 26;7:499. Epub 2018 Apr 26.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong.

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April 2018

A comprehensive web tool for toehold switch design.

Authors:

Andrew Ching-Yuet To David Ho-Ting Chu Angela Ruoning Wang Frances Cheuk-Yau Li Alan Wai-On Chiu Daisy Yuwei Gao Chung Hang Jonathan Choi Siu-Kai Kong Ting-Fung Chan King-Ming Chan Kevin Y Yip

Bioinformatics 2018 08;34(16):2862-2864

Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.

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August 2018

A network approach to exploring the functional basis of gene-gene epistatic interactions in disease susceptibility.

Authors:

Danny Kit-Sang Yip Landon L Chan Iris K Pang Wei Jiang Nelson L S Tang Weichuan Yu Kevin Y Yip

Bioinformatics 2018 05;34(10):1741-1749

Department of Computer Science and Engineering.

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May 2018

EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma.

Authors:

Raymond W-M Lung Pok-Man Hau Ken H-O Yu Kevin Y Yip Joanna H-M Tong Wing-Po Chak Anthony W-H Chan Ka-Hei Lam Angela Kwok-Fung Lo Edith K-Y Tin Shuk-Ling Chau Jesse C-S Pang Johnny S-H Kwan Pierre Busson Lawrence S Young Lee-Fah Yap Sai-Wah Tsao Ka-Fai To Kwok-Wai Lo

J Pathol 2018 04 16;244(4):394-407. Epub 2018 Feb 16.

Department of Anatomical and Cellular Pathology, State Key Laboratory in Oncology in South China and Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong.

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April 2018