Kevin W Gaido

Kevin W Gaido

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Kevin W Gaido

Kevin W Gaido

Publications by authors named "Kevin W Gaido"

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Pathway modeling of microarray data: a case study of pathway activity changes in the testis following in utero exposure to dibutyl phthalate (DBP).

Toxicol Appl Pharmacol 2013 Sep 17;271(3):386-94. Epub 2010 Sep 17.

Chemical and Biochemical Engineering Department, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.taap.2010.09.008DOI Listing
September 2013

Use of genomic data in risk assessment case study: II. Evaluation of the dibutyl phthalate toxicogenomic data set.

Toxicol Appl Pharmacol 2013 Sep 30;271(3):349-62. Epub 2011 Jun 30.

National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2011.06.014DOI Listing
September 2013

Human fetal testis xenografts are resistant to phthalate-induced endocrine disruption.

Environ Health Perspect 2012 Aug 17;120(8):1137-43. Epub 2012 Apr 17.

Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1289/ehp.1104711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440087PMC
August 2012

Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats.

Birth Defects Res B Dev Reprod Toxicol 2009 Aug;86(4):345-54

CIIT at The Hamner Institutes for Health Sciences, 6 Davis Drive, P.O. Box 12137, Research Triangle Park, NC 27709-2137, USA.

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http://dx.doi.org/10.1002/bdrb.20199DOI Listing
August 2009

GUDMAP: the genitourinary developmental molecular anatomy project.

J Am Soc Nephrol 2008 Apr 20;19(4):667-71. Epub 2008 Feb 20.

Department of Molecular and Cellular Biology and Harvard Stem Cell Institute, Harvard University, 16, Divinity Avenue, Cambridge, MA 02138, USA.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2007101078
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http://dx.doi.org/10.1681/ASN.2007101078DOI Listing
April 2008

Using a comparative in vivo DNase I footprinting technique to analyze changes in protein-DNA interactions following phthalate exposure.

J Biochem Mol Toxicol 2007 ;21(5):312-22

The Hamner Institutes for Health Sciences (Formerly CIIT Centers for Health Research), 6 Davis Drive, PO Box 12137, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1002/jbt.20192DOI Listing
February 2008

Mapping gene expression changes in the fetal rat testis following acute dibutyl phthalate exposure defines a complex temporal cascade of responding cell types.

Biol Reprod 2007 Dec 19;77(6):978-89. Epub 2007 Sep 19.

The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1095/biolreprod.107.062950DOI Listing
December 2007

CCAAT/enhancer binding protein beta, but not steroidogenic factor-1, modulates the phthalate-induced dysregulation of rat fetal testicular steroidogenesis.

Endocrinology 2007 Dec 20;148(12):5851-64. Epub 2007 Sep 20.

The Hamner Institutes for Health Sciences, 6 Davis Drive, Research Triangle Park, NC 27709-2137, USA.

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http://dx.doi.org/10.1210/en.2007-0930DOI Listing
December 2007

Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone.

Toxicol Sci 2007 Jun 14;97(2):491-503. Epub 2007 Mar 14.

The Hamner Institutes for Health Sciences Centers for Health Research, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfm049DOI Listing
June 2007

Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages.

Toxicol Sci 2006 Oct 29;93(2):369-81. Epub 2006 Jun 29.

Division of Biological Sciences, CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfl049DOI Listing
October 2006

Gene expression profiling of androgen receptor antagonists in the rat fetal testis reveals few common gene targets.

J Biochem Mol Toxicol 2006 ;20(1):7-17

CIIT Centers for Health Research, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1002/jbt.20110DOI Listing
May 2006

Analysis of variation of amplitudes in cell cycle gene expression.

Theor Biol Med Model 2005 Nov 11;2:46. Epub 2005 Nov 11.

CIIT Ceters for Health Research, 6 Davis Drive, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1186/1742-4682-2-46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315354PMC
November 2005

Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact.

Biol Reprod 2005 Sep 18;73(3):482-90. Epub 2005 May 18.

CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1095/biolreprod.104.037184DOI Listing
September 2005

Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis.

Biol Reprod 2005 Jul 23;73(1):180-92. Epub 2005 Feb 23.

CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1095/biolreprod.104.039404DOI Listing
July 2005

Altered gene expression during rat Wolffian duct development following di(n-butyl) phthalate exposure.

Toxicol Sci 2005 Jul 13;86(1):161-74. Epub 2005 Apr 13.

CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfi172DOI Listing
July 2005

Dose-response modeling in reproductive toxicology in the systems biology era.

Reprod Toxicol 2005 Jan-Feb;19(3):327-37

CIIT Centers for Health Research, Research Triangle Park, NC 27709-2137, USA.

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http://dx.doi.org/10.1016/j.reprotox.2004.12.004DOI Listing
June 2005

Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate.

Toxicol Sci 2004 Sep 12;81(1):60-8. Epub 2004 May 12.

CIIT Centers for Health Research, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfh169DOI Listing
September 2004

Di(n-butyl) phthalate impairs cholesterol transport and steroidogenesis in the fetal rat testis through a rapid and reversible mechanism.

Endocrinology 2004 Mar 14;145(3):1227-37. Epub 2003 Nov 14.

CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709-2137, USA.

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http://dx.doi.org/10.1210/en.2003-1475DOI Listing
March 2004

Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate.

Toxicol Sci 2003 Jun 15;73(2):431-41. Epub 2003 Apr 15.

CIIT Centers for Health Research, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfg087DOI Listing
June 2003

Interaction of organophosphate pesticides and related compounds with the androgen receptor.

Environ Health Perspect 2003 Apr;111(4):545-52

Department of Applied Biological Chemistry, Meijo University, Nagoya, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241442PMC
http://dx.doi.org/10.1289/ehp.5671DOI Listing
April 2003

17beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice.

Toxicol Sci 2002 Sep;69(1):42-8

Cell Signaling and Cancer Group, Department of Environmental and Molecular Toxicology, North Carolina State University, Campus Box 7633, Raleigh, North Carolina 27695, USA.

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http://dx.doi.org/10.1093/toxsci/69.1.42DOI Listing
September 2002

Effects of in utero exposure to the organophosphate insecticide fenitrothion on androgen-dependent reproductive development in the Crl:CD(SD)BR rat.

Toxicol Sci 2002 Jul;68(1):174-83

CIIT Centers for Health Research, P.O. Box 12137, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1093/toxsci/68.1.174DOI Listing
July 2002