Kevin Shianna

Kevin Shianna

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Kevin Shianna

Kevin Shianna

Publications by authors named "Kevin Shianna"

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Two further blood pressure loci identified in ion channel genes with a gene-centric approach.

Circ Cardiovasc Genet 2014 Dec 10;7(6):873-9. Epub 2014 Sep 10.

From the Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland (N.S.M., C.V., G.L.C., N.D., P.S., A.V.S.); Centre for Genetic Origins of Health and Disease, University of Western Australia, Perth, Australia (N.S.M.); Blood Pressure Unit and Department of Neurology, Beaumont Hospital, Beaumont, Dublin, Ireland (N.D., A.V.S.); Center for Human Genome Variation and Department of Medicine, Duke University School of Medicine, Durham, NC (K.V.S.); Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland (P.S., E.O.B.); Centre for Clinical Pharmacology, William Harvey Research Institute, Barts and the London Medical School, and Barts NIHR Biomedical Research Unit, London (P.B.M.); and Department of Cardiovascular Sciences, University of Leicester, and Leicester National Institute for Health Research Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, United Kingdom (N.M., M.T., N.J.S.).

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http://dx.doi.org/10.1161/CIRCGENETICS.113.000190DOI Listing
December 2014

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

Nat Commun 2014 Sep 4;5:4757. Epub 2014 Sep 4.

1] Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina 27599, USA [2] Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA [3] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77 Stockholm, Sweden [4].

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http://dx.doi.org/10.1038/ncomms5757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155508PMC
September 2014

Host genetics of HIV acquisition and viral control.

Annu Rev Med 2013 27;64:203-17. Epub 2012 Sep 27.

Center for Human Genome Variation, Duke University School of Medicine, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1146/annurev-med-052511-135400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296759PMC
July 2013

Prioritizing genetic variants for causality on the basis of preferential linkage disequilibrium.

Am J Hum Genet 2012 Sep 30;91(3):422-34. Epub 2012 Aug 30.

Center for Human Genome Variation, Duke University School of Medicine, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.ajhg.2012.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511993PMC
September 2012

A whole-genome analysis of premature termination codons.

Genomics 2011 Nov 22;98(5):337-42. Epub 2011 Jul 22.

Center for Human Genome Variation, Duke University School of Medicine, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.ygeno.2011.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282586PMC
November 2011

Exome sequencing: the expert view.

Genome Biol 2011 Sep 14;12(9):128. Epub 2011 Sep 14.

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http://dx.doi.org/10.1186/gb-2011-12-9-128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308041PMC
September 2011

SVA: software for annotating and visualizing sequenced human genomes.

Bioinformatics 2011 Jul 29;27(14):1998-2000. Epub 2011 May 29.

Center for Human Genome Variation, Duke University School of Medicine, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1093/bioinformatics/btr317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129530PMC
July 2011

Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase function.

Gastroenterology 2011 Apr 1;140(4):1314-21. Epub 2011 Jan 1.

Center for Human Genome Variation, School of Medicine, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.12.038DOI Listing
April 2011

A genome-wide comparison of the functional properties of rare and common genetic variants in humans.

Am J Hum Genet 2011 Apr 31;88(4):458-68. Epub 2011 Mar 31.

Center for Human Genome Variation, Duke University School of Medicine, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/j.ajhg.2011.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071924PMC
April 2011

Hepatitis C pharmacogenetics: state of the art in 2010.

Hepatology 2011 Jan;53(1):336-45

Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.

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http://www.institutoroche.es/web/pdf/curso19_20/HepatitisCph
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http://doi.wiley.com/10.1002/hep.24052
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http://dx.doi.org/10.1002/hep.24052DOI Listing
January 2011

Host genetics and HIV-1: the final phase?

PLoS Pathog 2010 Oct 14;6(10):e1001033. Epub 2010 Oct 14.

Center for Human Genome Variation, Duke University School of Medicine, Durham, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1001033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954832PMC
October 2010

Screening the human exome: a comparison of whole genome and whole transcriptome sequencing.

Genome Biol 2010 28;11(5):R57. Epub 2010 May 28.

Center for Human Genome Variation, Duke University School of Medicine, Box 91009, Durham, NC 27708, USA.

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http://dx.doi.org/10.1186/gb-2010-11-5-r57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898068PMC
September 2010

An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response.

Gastroenterology 2010 Sep 2;139(3):821-7, 827.e1. Epub 2010 Jun 2.

Liver Unit, Instituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.

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http://dx.doi.org/10.1053/j.gastro.2010.05.079DOI Listing
September 2010

A polymorphism in the HCP5 gene associated with HLA-B*5701 does not restrict HIV-1 in vitro.

AIDS 2010 Jan;24(1):155-7

Center for Human Genome Variation, Duke Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1097/QAD.0b013e32833202f5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652654PMC
January 2010

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.

Nature 2009 Sep 16;461(7262):399-401. Epub 2009 Aug 16.

Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1038/nature08309DOI Listing
September 2009

Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1.

PLoS Genet 2009 Sep 18;5(9):e1000657. Epub 2009 Sep 18.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734340PMC
September 2009

Common variants conferring risk of schizophrenia.

Nature 2009 Aug 1;460(7256):744-7. Epub 2009 Jul 1.

deCODE genetics, Sturlugata 8, IS-101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/nature08186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077530PMC
August 2009

Large recurrent microdeletions associated with schizophrenia.

Nature 2008 Sep;455(7210):232-6

CNS Division, deCODE genetics, Sturlugata 8, IS-101 Reykjavík, Iceland.

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http://dx.doi.org/10.1038/nature07229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687075PMC
September 2008

High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection.

PLoS One 2008 Aug 6;3(8):e2882. Epub 2008 Aug 6.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002882PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478710PMC
August 2008

Human genomics: in search of normality.

Nature 2006 Nov;444(7118):428-9

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http://dx.doi.org/10.1038/444428aDOI Listing
November 2006

Genomic characterization of POS5, the Saccharomyces cerevisiae mitochondrial NADH kinase.

Mitochondrion 2006 Apr 18;6(2):94-101. Epub 2006 Apr 18.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.mito.2006.02.003DOI Listing
April 2006