Publications by authors named "Kevin Litchfield"

34Publications

Identification of conserved evolutionary trajectories in tumors.

Bioinformatics 2020 Jul;36(Supplement_1):i427-i435

Cancer Data Science Lab., National Cancer Institute, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/bioinformatics/btaa453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355238PMC
July 2020

Evidence That STK19 Is Not an NRAS-dependent Melanoma Driver.

Cell 2020 Jun;181(6):1395-1405.e11

Mechanisms of Transcription Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298618PMC
June 2020

Large-scale Analysis Demonstrates Familial Testicular Cancer to have Polygenic Aetiology.

Eur Urol 2018 09 21;74(3):248-252. Epub 2018 Jun 21.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; William Harvey Research Institute, Queen Mary University, London, UK; Department of Clinical Genetics, Guys and St Thomas NHS Foundation Trust, London, UK; Public Health England, National Cancer Registration and Analysis Service, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.05.036DOI Listing
September 2018

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

Cell 2018 04 12;173(3):595-610.e11. Epub 2018 Apr 12.

Translational Cancer Therapeutics Laboratory, the Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence London, University College London Cancer Institute, London WC1E 6DD, UK; Department of Medical Oncology, University College London Hospitals, London NW1 2BU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938372PMC
April 2018

Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene.

Eur Urol 2018 06 9;73(6):828-831. Epub 2018 Feb 9.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; William Harvey Research Institute, Queen Mary University, London, UK; Department of Clinical Genetics, Guys and St Thomas NHS Foundation Trust, London, UK; National Cancer Registration and Analysis Service, Public Health England, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.01.021DOI Listing
June 2018

The GENIE Is Out of the Bottle: Landmark Cancer Genomics Dataset Released.

Cancer Discov 2017 08;7(8):796-798

Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, London, United Kingdom.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0604DOI Listing
August 2017

Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis.

Lancet Oncol 2017 08 7;18(8):1009-1021. Epub 2017 Jul 7.

Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, London, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, London, UK; Department of Medical Oncology, University College London Hospitals, London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045173051
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http://dx.doi.org/10.1016/S1470-2045(17)30516-8DOI Listing
August 2017

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

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http://dx.doi.org/10.1001/jamaoncol.2016.5945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638008PMC
May 2017

The genomic landscape of testicular germ cell tumours: from susceptibility to treatment.

Nat Rev Urol 2016 07 14;13(7):409-19. Epub 2016 Jun 14.

Division of Genetics and Epidemiology, Institute of Cancer Research, 15 Cotswold Road, London SM2 5NG, UK.

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http://dx.doi.org/10.1038/nrurol.2016.107DOI Listing
July 2016

Polygenic susceptibility to testicular cancer: implications for personalised health care.

Br J Cancer 2015 Nov 13;113(10):1512-8. Epub 2015 Oct 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London SW3 6JB, UK.

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http://dx.doi.org/10.1038/bjc.2015.334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815881PMC
November 2015

Quantifying the heritability of testicular germ cell tumour using both population-based and genomic approaches.

Sci Rep 2015 Sep 9;5:13889. Epub 2015 Sep 9.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW3 6JB, UK.

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http://dx.doi.org/10.1038/srep13889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563562PMC
September 2015

Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours.

Nat Commun 2015 Jan 22;6:5973. Epub 2015 Jan 22.

1] Division of Genetics and Epidemiology, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK [2] William Harvey Research Institute, Queen Mary University London, Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.1038/ncomms6973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338546PMC
January 2015