Kevin K Arien

Kevin K Arien

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Kevin K Arien

Kevin K Arien

Publications by authors named "Kevin K Arien"

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Challenges in diagnosing Zika-experiences from a reference laboratory in a non-endemic setting.

Eur J Clin Microbiol Infect Dis 2019 Apr 24;38(4):771-778. Epub 2019 Jan 24.

National Reference Center for Arboviruses, Department of Clinical Sciences, Institute of Tropical Medicine, Kronenburgstraat 43/3, Antwerp, Belgium.

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http://link.springer.com/10.1007/s10096-019-03472-8
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http://dx.doi.org/10.1007/s10096-019-03472-8DOI Listing
April 2019

Dengue vaccine: reliably determining previous exposure.

Lancet Glob Health 2018 08 22;6(8):e830-e831. Epub 2018 Jun 22.

Institute of Public Health, University of Heidelberg, Germany; London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1016/S2214-109X(18)30295-XDOI Listing
August 2018

Can Zika virus antibodies cross-protect against dengue virus?

Lancet Glob Health 2018 05;6(5):e494

National Reference Centre for Arboviruses, Department of Clinical Sciences, Institute of Tropical Medicine, B-2000 Antwerp, Belgium.

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http://dx.doi.org/10.1016/S2214-109X(18)30122-0DOI Listing
May 2018

Case report: tick-borne encephalitis (TBE) in a Belgian traveller returning from Germany.

J Travel Med 2018 01;25(1)

Department of Clinical Sciences, National Reference Centre for Arboviruses, Institute of Tropical Medicine, Antwerp, Belgium.

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http://dx.doi.org/10.1093/jtm/tay078DOI Listing
January 2018

Zika virus in semen: a prospective cohort study of symptomatic travellers returning to Belgium.

Bull World Health Organ 2017 Dec 6;95(12):802-809. Epub 2017 Jul 6.

Department of Clinical Sciences, Institute of Tropical Medicine, Kronenburgstraat 43/3, B-2000, Antwerp, Belgium.

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http://dx.doi.org/10.2471/BLT.17.181370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710082PMC
December 2017

High mortality in non-Ebola virus disease cases: need to provide timely and effective care.

Lancet Infect Dis 2017 10;17(10):1021-1022

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

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http://dx.doi.org/10.1016/S1473-3099(17)30523-6DOI Listing
October 2017

The HIV-1 transmission bottleneck.

Retrovirology 2017 03 23;14(1):22. Epub 2017 Mar 23.

Division of Immunology, Department of Pathology, Falmouth 3.25, University of Cape Town, Anzio Rd, Observatory, Cape Town, 7925, South Africa.

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http://dx.doi.org/10.1186/s12977-017-0343-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364581PMC
March 2017

Inhibition of HIV Virus by Neutralizing Vhh Attached to Dual Functional Liposomes Encapsulating Dapivirine.

Nanoscale Res Lett 2016 Dec 28;11(1):350. Epub 2016 Jul 28.

Department of Natural Sciences, Middlesex University, London, UK.

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http://dx.doi.org/10.1186/s11671-016-1558-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963346PMC
December 2016

Confirmed Zika virus infection in a Belgian traveler returning from Guatemala, and the diagnostic challenges of imported cases into Europe.

J Clin Virol 2016 07 14;80:8-11. Epub 2016 Apr 14.

National Reference Center for Arboviruses, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jcv.2016.04.009DOI Listing
July 2016

Resistance and cross-resistance profile of the diaryltriazine NNRTI and candidate microbicide UAMC01398.

J Antimicrob Chemother 2016 May 4;71(5):1159-68. Epub 2016 Feb 4.

Department of Biomedical Sciences, Institute of Tropical Medicine, B-2000 Antwerp, Belgium Department of Biomedical Sciences, University of Antwerp, B-2000 Antwerp, Belgium.

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http://dx.doi.org/10.1093/jac/dkv501DOI Listing
May 2016

Aerosol Transmission of Filoviruses.

Viruses 2016 05 23;8(5). Epub 2016 May 23.

Virology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, Antwerp B-2000, Belgium.

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http://dx.doi.org/10.3390/v8050148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885103PMC
May 2016

Letter to the editor: Specificity of Zika virus ELISA: interference with malaria.

Euro Surveill 2016 May;21(21)

National Reference Center for Arboviruses, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

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http://dx.doi.org/10.2807/1560-7917.ES.2016.21.21.30237DOI Listing
May 2016

2,6-Di(arylamino)-3-fluoropyridine Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors.

J Med Chem 2016 Mar 8;59(5):1854-68. Epub 2016 Feb 8.

Organic Synthesis Division, Department of Chemistry, University of Antwerp , Groenenborgerlaan 171, B-2020 Antwerp, Belgium.

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http://pubs.acs.org/doi/10.1021/acs.jmedchem.5b01336
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http://dx.doi.org/10.1021/acs.jmedchem.5b01336DOI Listing
March 2016

From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.

Bioorg Med Chem 2014 Oct 14;22(19):5241-8. Epub 2014 Aug 14.

Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2014.08.005DOI Listing
October 2014

In vitro and ex vivo evaluation of polymeric nanoparticles for vaginal and rectal delivery of the anti-HIV drug dapivirine.

Mol Pharm 2013 Jul 17;10(7):2793-807. Epub 2013 Jun 17.

Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto , Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.

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http://dx.doi.org/10.1021/mp4002365DOI Listing
July 2013

M48U1 CD4 mimetic has a sustained inhibitory effect on cell-associated HIV-1 by attenuating virion infectivity through gp120 shedding.

Retrovirology 2013 Feb 1;10:12. Epub 2013 Feb 1.

Department of Biomedical Sciences, Unit of Virology, Institute of Tropical Medicine, Antwerp, B-2000, Belgium.

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http://dx.doi.org/10.1186/1742-4690-10-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571899PMC
February 2013

Synthesis, evaluation and structure-activity relationships of triazine dimers as novel antiviral agents.

Bioorg Med Chem Lett 2012 Dec 27;22(23):7174-8. Epub 2012 Sep 27.

Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.bmcl.2012.09.066DOI Listing
December 2012

A catalogue of putative HIV-1 protease host cell substrates.

Biol Chem 2012 Sep;393(9):915-31

Department of Medical Protein Research and Biochemistry, VIB, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1515/hsz-2012-0168DOI Listing
September 2012

Polymeric nanoparticles affect the intracellular delivery, antiretroviral activity and cytotoxicity of the microbicide drug candidate dapivirine.

Pharm Res 2012 Jun 10;29(6):1468-84. Epub 2011 Nov 10.

Laboratory of Pharmaceutical Technology, LTF/CICF Faculty of Pharmacy, University of Porto, Rua Aníbal Cunha, 164, 4050-047, Porto, Portugal.

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http://dx.doi.org/10.1007/s11095-011-0622-3DOI Listing
June 2012

In vitro activities of candidate microbicides against cell-associated HIV.

Antimicrob Agents Chemother 2012 Feb 14;56(2):805-15. Epub 2011 Nov 14.

Virology Unit, Institute of Tropical Medicine, Antwerp, Belgium.

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http://dx.doi.org/10.1128/AAC.05801-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264207PMC
February 2012

Ex vivo models of HIV sexual transmission and microbicide development.

Curr HIV Res 2012 Jan;10(1):73-8

Virology Unit, Division of Microbiology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

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January 2012

A dual-chamber model of the female genital tract to evaluate epithelial toxicity of candidate anti-HIV microbicides.

Curr Protoc Cell Biol 2011 Sep;Chapter 26:Unit26.13

Virology Unit, Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium.

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http://dx.doi.org/10.1002/0471143030.cb2613s52DOI Listing
September 2011

HIV sexual transmission and microbicides.

Rev Med Virol 2011 Mar 15;21(2):110-33. Epub 2011 Mar 15.

Virology Unit, Department of Microbiology, Institute of Tropical Medicine, Antwerpen, Belgium.

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http://dx.doi.org/10.1002/rmv.684DOI Listing
March 2011

In vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides.

Antimicrob Agents Chemother 2010 Dec 4;54(12):5105-14. Epub 2010 Oct 4.

Department of Microbiology, Virology Unit, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium.

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http://dx.doi.org/10.1128/AAC.00456-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981258PMC
December 2010

First real success for anti-HIV gel: a new start for HIV microbicides?

Future Microbiol 2010 Nov;5(11):1621-3

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http://dx.doi.org/10.2217/fmb.10.129DOI Listing
November 2010

Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness.

Retrovirology 2010 Jul 20;7:60. Epub 2010 Jul 20.

Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam (CINIMA), Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1742-4690-7-60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918528PMC
July 2010

Development of an in vitro dual-chamber model of the female genital tract as a screening tool for epithelial toxicity.

J Virol Methods 2010 May 4;165(2):186-97. Epub 2010 Feb 4.

Virology Unit, Department of Microbiology, Institute of Tropical Medicine, B-2000 Antwerpen, Belgium.

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http://dx.doi.org/10.1016/j.jviromet.2010.01.018DOI Listing
May 2010

Rho GTPase Cdc42 is essential for human T-cell development.

Haematologica 2010 Mar;95(3):367-75

Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.3324/haematol.2009.006890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833065PMC
March 2010

HIV Nef: role in pathogenesis and viral fitness.

Curr HIV Res 2008 May;6(3):200-8

HIVLab, Department of Clinical Chemistry, Microbiology and Immunology, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, 4blokA, B-9000 Gent, Belgium.

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May 2008

Survey of the temporal changes in HIV-1 replicative fitness in the Amsterdam Cohort.

Virology 2007 Jul 28;364(1):140-6. Epub 2007 Mar 28.

Department of Microbiology, Virology Unit, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.virol.2007.02.021DOI Listing
July 2007

Is HIV-1 evolving to a less virulent form in humans?

Nat Rev Microbiol 2007 02 4;5(2):141-51. Epub 2007 Jan 4.

HIV and Retrovirology Research Unit, Department of Microbiology, Institute of Tropical Medicine, Nationalestraat 155, B2000 Antwerp, Belgium.

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http://dx.doi.org/10.1038/nrmicro1594DOI Listing
February 2007

Replicative fitness of CCR5-using and CXCR4-using human immunodeficiency virus type 1 biological clones.

Virology 2006 Mar 28;347(1):65-74. Epub 2005 Dec 28.

HIV and Retrovirology Research Unit, Department of Microbiology, Institute for Tropical Medicine, Nationalestraat 155, B-2000 Antwerpen, Belgium.

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http://dx.doi.org/10.1016/j.virol.2005.11.045DOI Listing
March 2006

Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time.

AIDS 2005 Oct;19(15):1555-64

Department of Microbiology, HIV and Retrovirology Research Unit, Institute of Tropical Medicine, Antwerp, Belgium.

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October 2005