Publications by authors named "Kevin Gough"

80Publications

Infection par le SRAS-CoV-2 associée à un pneumothorax spontané.

CMAJ 2020 10;192(43):E1334-E1335

Hôpital St. Michael, Université de Toronto, Toronto, Ont.

View Article and Find Full Text PDF
October 2020

SARS-CoV-2 infection associated with spontaneous pneumothorax.

CMAJ 2020 05 21;192(19):E510. Epub 2020 Apr 21.

St. Michael's Hospital, University of Toronto, Toronto, Ont.

View Article and Find Full Text PDF
May 2020

fungemia after travel to China in a Canadian patient with AIDS.

CMAJ 2020 Jan;192(4):E92-E95

Department of Medicine (Waters) and Division of Infectious Diseases (Beliavsky, Gough), Department of Medicine, University of Toronto; Division of Infectious Diseases (Gough), St. Michael's Hospital, Toronto, Ont.

View Article and Find Full Text PDF
January 2020

Advances in the Production and Batch Reformatting of Phage Antibody Libraries.

Mol Biotechnol 2019 Nov;61(11):801-815

School of Veterinary Medicine and Science, The University of Nottingham, College Rd., Sutton Bonington, Loughborough, Leicestershire, LE12 5RD, UK.

View Article and Find Full Text PDF
November 2019

BSE infectivity survives burial for five years with only limited spread.

Arch Virol 2019 Apr 24;164(4):1135-1145. Epub 2019 Feb 24.

The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, Scotland, UK.

View Article and Find Full Text PDF
April 2019

Rapid recontamination of a farm building occurs after attempted prion removal.

Vet Rec 2019 Jan 2;184(3):97. Epub 2019 Jan 2.

ADAS, School of Veterinary Medicine and Science, The University of Nottingham, Loughborough, UK.

View Article and Find Full Text PDF
January 2019

Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11.

J Biol Chem 2019 01 29;294(2):424-436. Epub 2018 Oct 29.

From the Centre for Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD,

View Article and Find Full Text PDF
January 2019

The Chronic Stages of Bovine Are Dominated by CD4 T-Cell Exhaustion.

Front Immunol 2017 21;8:1002. Epub 2017 Aug 21.

Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.

View Article and Find Full Text PDF
August 2017

The detection of great crested newts year round via environmental DNA analysis.

BMC Res Notes 2017 Jul 26;10(1):327. Epub 2017 Jul 26.

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Leicestershire, LE12 5RD, UK.

View Article and Find Full Text PDF
July 2017

How is Europe positioned for a re-emergence of Schmallenberg virus?

Vet J 2017 Dec 3;230:45-51. Epub 2017 May 3.

School of Veterinary Medicine and Science the University of Nottingham, Sutton Bonington Campus, Leicestershire, LE12 5RD, United Kingdom. Electronic address:

View Article and Find Full Text PDF
December 2017

Ovine recombinant PrP as an inhibitor of ruminant prion propagation in vitro.

Prion 2017 07 30;11(4):265-276. Epub 2017 Jun 30.

a School of Veterinary Medicine and Science , The University of Nottingham , Sutton Bonington , Leicestershire , UK.

View Article and Find Full Text PDF
July 2017

Expression of four S. pneumoniae type 2 polysaccharide biosynthetic enzymes utilising the endogenous Kex2 protease activity in tobacco.

Pak J Pharm Sci 2017 Mar;30(2):439-448

ADAS Biotechnology Group, Department of Biology, University of Leicester, University Rd, Leicester, UK LE1 7RH.

View Article and Find Full Text PDF
March 2017

In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification.

Prion 2017 01 8;11(1):54-64. Epub 2017 Feb 8.

a School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus , College Road, Sutton Bonington , Leicestershire , UK.

View Article and Find Full Text PDF
January 2017

A Trematode Parasite Derived Growth Factor Binds and Exerts Influences on Host Immune Functions via Host Cytokine Receptor Complexes.

PLoS Pathog 2016 Nov 2;12(11):e1005991. Epub 2016 Nov 2.

Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.

View Article and Find Full Text PDF
November 2016

Mapping polyclonal antibody responses to bacterial infection using next generation phage display.

Sci Rep 2016 Apr 13;6:24232. Epub 2016 Apr 13.

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, College Road, Sutton Bonington, Leicestershire, LE12 5RD, UK.

View Article and Find Full Text PDF
April 2016

Objects in Contact with Classical Scrapie Sheep Act as a Reservoir for Scrapie Transmission.

Front Vet Sci 2015 14;2:32. Epub 2015 Sep 14.

Animal Sciences Unit, Animal and Plant Health Agency Weybridge , Addlestone , UK.

View Article and Find Full Text PDF
December 2015

Methods for Differentiating Prion Types in Food-Producing Animals.

Biology (Basel) 2015 Nov 13;4(4):785-813. Epub 2015 Nov 13.

ADAS UK, School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, College Road, Sutton Bonington, Leicestershire LE12 5RD, UK.

View Article and Find Full Text PDF
November 2015

Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells.

Respir Res 2015 Jul 15;16:86. Epub 2015 Jul 15.

Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
July 2015

Use of Compassionate Supply of Antiretroviral Drugs to Avoid Treatment Interruptions or Delayed Treatment Initiation among HIV-Positive Patients Living in Ontario: A Retrospective Review.

Healthc Policy 2015 Feb;10(3):64-77

Associate Professor, Department of Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON.

View Article and Find Full Text PDF
February 2015

Incubation of ovine scrapie with environmental matrix results in biological and biochemical changes of PrP(Sc) over time.

Vet Res 2015 May 1;46:46. Epub 2015 May 1.

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, College Road, Sutton Bonington, Leicestershire, UK.

View Article and Find Full Text PDF
May 2015

Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows.

BMC Vet Res 2015 Mar 11;11:56. Epub 2015 Mar 11.

Wood Veterinary Group, 125 Bristol Road, Quedgeley, Gloucester, GL2 4NB, UK.

View Article and Find Full Text PDF
March 2015

Circulation of prions within dust on a scrapie affected farm.

Vet Res 2015 Apr 16;46:40. Epub 2015 Apr 16.

ADAS UK, School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington, Loughborough, Leicestershire, LE12 5RD, UK.

View Article and Find Full Text PDF
April 2015

Sensitive recovery of recombinant antibody clones after their in silico identification within NGS datasets.

J Immunol Methods 2015 May 13;420:50-5. Epub 2015 Mar 13.

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington, Loughborough, Leicestershire LE12 5RD, UK. Electronic address:

View Article and Find Full Text PDF
May 2015

The application of eDNA for monitoring of the Great Crested Newt in the UK.

Ecol Evol 2014 Nov 30;4(21):4023-32. Epub 2014 Sep 30.

School of Veterinary Medicine and Science, The University of Nottingham Sutton Bonington Campus, Leicestershire, LE12 5RD, U.K.

View Article and Find Full Text PDF
November 2014

Persistence of ovine scrapie infectivity in a farm environment following cleaning and decontamination.

Vet Rec 2015 Jan 31;176(4):99. Epub 2014 Oct 31.

ADAS UK, School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington, Loughborough, Leicestershire LE12 5RD, UK.

View Article and Find Full Text PDF
January 2015

Highly sensitive detection of small ruminant bovine spongiform encephalopathy within transmissible spongiform encephalopathy mixes by serial protein misfolding cyclic amplification.

J Clin Microbiol 2014 Nov 20;52(11):3863-8. Epub 2014 Aug 20.

ADAS-UK, The University of Nottingham, Sutton Bonington, Leicestershire, United Kingdom

View Article and Find Full Text PDF
November 2014

Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines.

PLoS One 2014 3;9(2):e88144. Epub 2014 Feb 3.

Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, Leicestershire, United Kingdom.

View Article and Find Full Text PDF
October 2014

Paying more than lip service to an oral lesion: a case of plasmablastic lymphoma.

BMJ Case Rep 2012 Jul 13;2012. Epub 2012 Jul 13.

Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

View Article and Find Full Text PDF
July 2012

Temperature influences the interaction of ruminant PrP (TSE) with soil.

Prion 2012 Jul 1;6(3):302-8. Epub 2012 Jul 1.

ADAS UK, School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington, Leicestershire, UK.

View Article and Find Full Text PDF
July 2012

A potential drug-herbal interaction between Ginkgo biloba and efavirenz.

J Int Assoc Physicians AIDS Care (Chic) 2012 Mar-Apr;11(2):98-100. Epub 2012 Feb 9.

1Department of Medicine, Division of Infectious Diseases, St Michael's Hospital, Toronto, ON, Canada.

View Article and Find Full Text PDF
February 2014

A case of a potential drug interaction between clobazam and etravirine-based antiretroviral therapy.

Antivir Ther 2012 4;17(3):589-92. Epub 2011 Nov 4.

Department of Infectious Diseases & HIV, St Michael's Hospital, Toronto, ON, Canada.

View Article and Find Full Text PDF
August 2012

Enhanced podcasts for teaching biochemistry to veterinary students.

Authors:
Kevin C Gough

Biochem Mol Biol Educ 2011 Nov-Dec;39(6):421-5

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire LE12 5RD, UK.

View Article and Find Full Text PDF
March 2012

The oral secretion of infectious scrapie prions occurs in preclinical sheep with a range of PRNP genotypes.

J Virol 2012 Jan 19;86(1):566-71. Epub 2011 Oct 19.

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire, United Kingdom.

View Article and Find Full Text PDF
January 2012

Differentiating ovine BSE from CH1641 scrapie by serial protein misfolding cyclic amplification.

Mol Biotechnol 2012 Jul;51(3):233-9

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, College Road, Sutton Bonington, Leicestershire LE12 5RD, UK.

View Article and Find Full Text PDF
July 2012

Development of competitive immunoassays to hydroxyl containing fungicide metabolites.

J Environ Sci Health B 2011 ;46(7):581-9

School of Veterinary Medicine and Science, University of Nottingham, Leicestershire, UK.

View Article and Find Full Text PDF
October 2011

Detection of prions in the faeces of sheep naturally infected with classical scrapie.

Vet Res 2011 May 18;42:65. Epub 2011 May 18.

Animal Health and Veterinary Laboratories Agency, Woodham Lane, New Haw, Addlestone, Surrey, KT15 3NB, UK.

View Article and Find Full Text PDF
May 2011

The interaction of ruminant PrP(Sc) with soils is influenced by prion source and soil type.

Environ Sci Technol 2010 Nov 22;44(22):8503-8. Epub 2010 Oct 22.

ADAS U.K., Department of Biology, University of Leicester, Leicester, LE1 7RH, UK.

View Article and Find Full Text PDF
November 2010

Prion transmission: prion excretion and occurrence in the environment.

Prion 2010 Oct-Dec;4(4):275-82. Epub 2010 Oct 17.

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, UK.

View Article and Find Full Text PDF
June 2011

Environmental sources of scrapie prions.

J Virol 2010 Nov 25;84(21):11560-2. Epub 2010 Aug 25.

ADAS UK, Department of Biology, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
November 2010

Immune activation and neuropsychiatric symptoms in HIV infection.

J Neuropsychiatry Clin Neurosci 2010 ;22(3):321-8

St. Michael's Hospital, Neurobehavioural Research Unit in HIV/AIDS, 30 Bond Street, Shuter Wing, Rm. 2-044, Toronto, ON, M5B 1W8.

View Article and Find Full Text PDF
November 2010

A retrospective investigation into risk factors of sarcoptic mange in dogs.

Parasitol Res 2010 Jul 20;107(2):279-83. Epub 2010 Apr 20.

The School of Veterinary Medicine and Science, College Road, University of Nottingham, Sutton Bonington Campus, Leicestershire, LE12 5RD, UK.

View Article and Find Full Text PDF
July 2010

Prions are secreted into the oral cavity in sheep with preclinical scrapie.

J Infect Dis 2010 Jun;201(11):1672-6

ADAS UK, Department of Biology, University of Leicester, Leicestershire, United Kingdom.

View Article and Find Full Text PDF
June 2010

In vitro amplification of prions from milk in the detection of subclinical infections.

Prion 2009 Oct-Dec;3(4):236-9. Epub 2009 Oct 23.

School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington, Leicestershire, UK.

View Article and Find Full Text PDF
March 2010

Development of immunoassays for the detection of the fungicide penconazole and its urinary metabolite.

J Agric Food Chem 2009 Oct;57(20):9393-9

Department of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Loughborough, Leicestershire, LE12 5RD, UK.

View Article and Find Full Text PDF
October 2009

A possible cluster of sexually transmitted Entamoeba histolytica: genetic analysis of a highly virulent strain.

Clin Infect Dis 2009 Aug;49(3):346-53

Division of Infectious Diseases, Department of Medicine, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada.

View Article and Find Full Text PDF
August 2009

Concentration of disease-associated prion protein with silicon dioxide.

Mol Biotechnol 2009 Mar 5;41(3):254-62. Epub 2008 Dec 5.

Department of Biology, University of Leicester, University Road, Leicester, LE1 7RH, UK.

View Article and Find Full Text PDF
March 2009

Molecular profiling of ovine prion diseases by using thermolysin-resistant PrPSc and endogenous C2 PrP fragments.

J Virol 2007 Oct 25;81(19):10532-9. Epub 2007 Jul 25.

ADAS UK, Department of Biology, Adrian Building, University of Leicester, University Road, Leicester LE1 7RH, Leicestershire, United Kingdom.

View Article and Find Full Text PDF
October 2007

Use of thermolysin in the diagnosis of prion diseases.

Mol Biotechnol 2007 Feb;35(2):161-70

ADAS UK, Department of Biology, Adrian Building, University of Leicester, University Road, Leicester, LE1 7RH, UK.

View Article and Find Full Text PDF
February 2007

Cellular prion protein in ovine milk.

Biochem Biophys Res Commun 2007 Feb 8;353(1):195-9. Epub 2006 Dec 8.

ADAS UK, Department of Biology, University of Leicester, University Road, Leicester, LE1 7RH, UK.

View Article and Find Full Text PDF
February 2007

Recombinant anti-EspA antibodies block Escherichia coli O157:H7-induced attaching and effacing lesions in vitro.

Microbes Infect 2006 Feb 19;8(2):426-33. Epub 2005 Sep 19.

Veterinary Laboratories Agency, Department of Food and Environmental Safety, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK.

View Article and Find Full Text PDF
February 2006

Early-onset pentamidine-associated second-degree heart block and sinus bradycardia: case report and review of the literature.

Pharmacotherapy 2005 Jun;25(6):899-903

Department of Family and Community Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.

View Article and Find Full Text PDF
June 2005

Severe acute respiratory syndrome in pregnancy.

Obstet Gynecol 2005 Jan;105(1):124-7

Department of Obstetrics and Gynecology, Division of Infectious Diseases, St. Michael's Hospital, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

View Article and Find Full Text PDF
January 2005

Isolation of recombinant antibodies against EspA and intimin of Escherichia coli O157:H7.

J Clin Microbiol 2004 Jul;42(7):2966-76

Department of Biology, Adrian Building, University of Leicester, University Rd., Leicester LE1 7RH, Leicestershire, United Kingdom.

View Article and Find Full Text PDF
July 2004

Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid.

Clin Infect Dis 2004 Mar 11;38(5):e38-40. Epub 2004 Feb 11.

Department of Family and Community Medicine, St. Michael's Hospital, Toronto, Ontario, Canada,

View Article and Find Full Text PDF
March 2004

Symptomatic primary HIV infection or risk experiences? Circumstances surrounding HIV testing and diagnosis among recent seroconverters.

Int J STD AIDS 2003 Sep;14(9):601-8

HIV Social, Behavioural and Epidemiological Studies Unit, Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada.

View Article and Find Full Text PDF
September 2003