Kevin E Thorpe

Kevin E Thorpe

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Kevin E Thorpe

Kevin E Thorpe

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Agreement between a health claims algorithm and parent-reported asthma in young children.

Pediatr Pulmonol 2019 Oct 22;54(10):1547-1556. Epub 2019 Jul 22.

Child Health Evaluative Sciences, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/ppul.24432DOI Listing
October 2019

Symptoms of depression and cognitive impairment in young adults after stroke/transient ischemic attack.

Psychiatry Res 2019 Sep 1;279:361-363. Epub 2019 Jul 1.

Department of Medicine (Neurology), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Hurvitz Brain Sciences Research Program, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2019.06.022DOI Listing
September 2019

A qualitative study to understand parent and physician perspectives about cow's milk fat for children.

Public Health Nutr 2019 Sep 2:1-8. Epub 2019 Sep 2.

Department of Nutritional Sciences, University of Toronto, Toronto,Canada.

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http://dx.doi.org/10.1017/S136898001900243XDOI Listing
September 2019

Acute kidney injury with sodium-glucose co-transporter-2 inhibitors: A meta-analysis of cardiovascular outcome trials.

Diabetes Obes Metab 2019 Aug 24;21(8):1996-2000. Epub 2019 May 24.

Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/dom.13754DOI Listing
August 2019

Relationship Among Diabetes Distress, Decisional Conflict, Quality of Life, and Patient Perception of Chronic Illness Care in a Cohort of Patients With Type 2 Diabetes and Other Comorbidities.

Diabetes Care 2019 Jul 2;42(7):1170-1177. Epub 2019 May 2.

Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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http://dx.doi.org/10.2337/dc18-1256DOI Listing
July 2019

Activity Tracker to Prescribe Various Exercise Intensities in Breast Cancer Survivors.

Med Sci Sports Exerc 2019 05;51(5):930-940

Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, Calgary, Alberta, CANADA.

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http://dx.doi.org/10.1249/MSS.0000000000001890DOI Listing
May 2019

Trajectories of Response to Dorsolateral Prefrontal rTMS in Major Depression: A THREE-D Study.

Am J Psychiatry 2019 May 15;176(5):367-375. Epub 2019 Feb 15.

The Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto (Kaster, Knyahnytska, Daskalakis, Blumberger); the Department of Psychiatry (Kaster, Downar, Giacobbe, Kennedy, Daskalakis, Blumberger), the Institute of Medical Science (Downar, Giacobbe, Kennedy, Daskalakis, Blumberger), and the Dalla Lana School of Public Health (Thorpe), University of Toronto, Toronto; the MRI-Guided rTMS Clinic, Toronto Western Hospital, Toronto (Downar); the Krembil Research Institute, University Health Network, Toronto (Downar, Kennedy); the Department of Psychiatry, University of British Columbia, Vancouver (Vila-Rodriguez, Lam); the Non-Invasive Neurostimulation Therapies Laboratory, University of British Columbia, Vancouver (Vila-Rodriguez); the Shalvata Mental Health Center, Hod-Hasharon, Israel, and the Sackler School of Medicine, Tel Aviv University, Tel Aviv (Feffer); the Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo (Noda); the Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre, Toronto (Giacobbe); and the Li Ka Shing Knowledge Institute, Saint Michael's Hospital, Toronto (Kennedy).

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http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2018.18
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http://dx.doi.org/10.1176/appi.ajp.2018.18091096DOI Listing
May 2019

Repetitive transcranial magnetic stimulation for depression - Authors' reply.

Lancet 2019 02;393(10170):403-404

Department of Psychiatry and Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, ON, Canada; MRI-Guided rTMS Clinic and Krembil Research Institute, University Health Network, Toronto, Canada.

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http://dx.doi.org/10.1016/S0140-6736(18)32837-XDOI Listing
February 2019

Leveraging pragmatic clinical trial design to advance phosphate management in end-stage renal disease.

Curr Opin Nephrol Hypertens 2019 01;28(1):34-39

Division of Nephrology, St. Joseph's Healthcare Hamilton, McMaster University.

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http://dx.doi.org/10.1097/MNH.0000000000000460DOI Listing
January 2019

25-hydroxyvitamin D and health service utilization for asthma in early childhood.

Pediatr Pulmonol 2018 08 15;53(8):1018-1026. Epub 2018 Jun 15.

Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/ppul.24067DOI Listing
August 2018

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study.

Lancet 2018 06;391(10140):2631-2640

Department of Anesthesia, University of Toronto, Toronto, ON, Canada; Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada; Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183113
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http://dx.doi.org/10.1016/S0140-6736(18)31131-0DOI Listing
June 2018

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial.

Lancet 2018 04 26;391(10131):1683-1692. Epub 2018 Apr 26.

Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada; Centre for Mental Health, University Health Network, Toronto, ON, Canada; MRI-Guided rTMS Clinic, University Health Network, Toronto, ON, Canada; Krembil Research Institute, University Health Network, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183029
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http://dx.doi.org/10.1016/S0140-6736(18)30295-2DOI Listing
April 2018

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery.

N Engl J Med 2017 11 12;377(22):2133-2144. Epub 2017 Nov 12.

From the Department of Anesthesia (C.D.M., G.M.T.H.) and the Department of Surgery, Division of Cardiac Surgery (S.V.), Keenan Research Centre for Biomedical Science and Li Ka Shing Knowledge Institute of St. Michael's Hospital, Applied Health Research Centre (AHRC), Li Ka Shing Knowledge Institute of St. Michael's Hospital (J.H., A.C.), Sunnybrook Health Sciences Center (S.F.), AHRC, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Dalla Lana School of Public Health (K.E.T.), and AHRC, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Department of Medicine and Institute of Health Policy, Management and Evaluation (P.J.), University of Toronto, and the Departments of Medicine, Laboratory Medicine, and Pathobiology, Institute of Health Policy, Management, and Evaluation, University of Toronto, and the Division of Hematology, Mount Sinai Hospital, Canadian Blood Services (N.S.), Toronto, Population Health Research Institute (R.P.W., E.B.-C.), Hamilton Health Sciences Centre (R.P.W., E.B.-C., K.C.), and McMaster University (R.P.W., E.B.-C., S.S.), Hamilton, ON, Ottawa Hospital Research Institute, University of Ottawa, Ottawa (D.A.F.), the Department of Anesthesia, Foothills Medical Centre, University of Calgary, Calgary, AB (A.J.G.), Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC (É.M.), the Departments of Anesthesia and Medicine, Division of Critical Care, Centre Hospitalier de l'Université de Montréal, Montreal (F.M.C.), the Departments of Anesthesia and Surgery, University of Manitoba, St. Boniface Hospital, Winnipeg (H.P.G.), the Department of Anesthesiology and Critical Care Medicine, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Laval, QC (F.L.), and the Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton (S.M.B.) - all in Canada; the Department of Cardiothoracic Anesthesia, Rigshospitalet, Copenhagen University Hospital, Copenhagen (B.K.); Medical Research Institute of New Zealand, Wellington (S.M., P.J.Y.), and Waikato Hospital, Hamilton (K.B.) - both in New Zealand; the Department of Surgery, University of Melbourne (A.R., C.R.), and the Department of Anaesthesia and Pain Management, Royal Melbourne Hospital (C.R.), Melbourne, VIC, and the Department of Anaesthesia, Royal Adelaide Hospital, Discipline of Acute Care Medicine, University of Adelaide, Adelaide, SA (T.W.P.) - all in Australia; Fundación Cardioinfantil-Instituto de Cardiología, Bogota, and Universidad Autónoma de Bucaramanga, Bucaramanga - both in Colombia (J.C.V.); the University of Basel, Department of Anesthesia, Surgical Intensive Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, and Klinik Hirslanden, Zurich - both in Switzerland (M.D.S.); the Department of Cardiothoracic Anesthesia, National Heart Center, and the Department of Anesthesiology, Singapore General Hospital, Singapore (N.C.H.); and Heart Care Associates, Ahmedabad, India (C.M.).

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http://dx.doi.org/10.1056/NEJMoa1711818DOI Listing
November 2017

The Dx-AF study: a prospective, multicenter, randomized controlled trial comparing VDD-ICD to VVI-ICD in detecting sub-clinical atrial fibrillation in defibrillator patients.

J Interv Card Electrophysiol 2017 Oct 27;50(1):57-63. Epub 2017 Jul 27.

Arrhythmia Services, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Suite D-377, Toronto, Ontario, M4N 3M5, Canada.

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http://dx.doi.org/10.1007/s10840-017-0276-0DOI Listing
October 2017

Re-Evaluation of Serum Ferritin Cut-Off Values for the Diagnosis of Iron Deficiency in Children Aged 12-36 Months.

J Pediatr 2017 09 18;188:287-290. Epub 2017 Apr 18.

Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Pediatrics Outcomes Research Team, Division of Pediatric Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Canada; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2017.03.028DOI Listing
September 2017

25-Hydroxyvitamin D supplementation and health-service utilization for upper respiratory tract infection in young children.

Public Health Nutr 2017 Jul 5;20(10):1816-1824. Epub 2017 Jun 5.

1Li Ka Shing Knowledge Institute,St. Michael's Hospital,209 Victoria Street,Toronto,ON,Canada,M5B 1T8.

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http://dx.doi.org/10.1017/S1368980017000921DOI Listing
July 2017

Vitamin D and Fracture Risk in Early Childhood: A Case-Control Study.

Am J Epidemiol 2017 06;185(12):1255-1262

Applied Health Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/aje/kww204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859980PMC
June 2017

How to construct regression models for observational studies (and how NOT to do it!).

Authors:
Kevin E Thorpe

Can J Anaesth 2017 05 24;64(5):461-470. Epub 2017 Feb 24.

Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.

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http://link.springer.com/10.1007/s12630-017-0833-0
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http://dx.doi.org/10.1007/s12630-017-0833-0DOI Listing
May 2017

A Randomized Control Trial Using a Validated Prediction Model for Diagnosing Acute Heart Failure in Undifferentiated Dyspneic Emergency Department Patients-Results of the GASP4Ar Study.

J Card Fail 2017 Feb 24;23(2):145-152. Epub 2016 Aug 24.

Departments of Anaesthesia and Critical Care, Keenan Research Centre for Biomedical Science and Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada; Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cardfail.2016.08.007DOI Listing
February 2017

Persistent Atrial Fibrillation Ablation in Females: Insight from the MAGIC-AF Trial.

J Cardiovasc Electrophysiol 2016 Nov 30;27(11):1259-1263. Epub 2016 Aug 30.

Helmsley Cardiac Arrhythmia Service, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1111/jce.13051DOI Listing
November 2016

Optimizing Pain and Rehabilitation After Knee Arthroplasty: A Two-Center, Randomized Trial.

Anesth Analg 2016 11;123(5):1316-1324

From the *Department of Anesthesia, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada; †Department of Anesthesia, St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada; ‡Division of Orthopedic Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada; §Department of Anesthesia, McMaster University Medical Centre, Hamilton, Ontario, Canada; ‖Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; ¶Canada Research Chair in Health Physiology, Faculty of Health, Department of Psychology, York University, Toronto, Ontario, Canada; #Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada; and **Department of Anesthesiology, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1213/ANE.0000000000001469DOI Listing
November 2016

Potential Cost-Effectiveness of Ambulatory Cardiac Rhythm Monitoring After Cryptogenic Stroke.

Stroke 2016 09 28;47(9):2380-5. Epub 2016 Jul 28.

From the Centre for Excellence in Economic Analysis Research (CLEAR), Toronto, ON, Canada (J.H.E.Y, J.S.H.); Applied Health Research Centre, Toronto, ON, Canada (K.E.T.); HUB Research Solutions, Li Ka Shing Centre for Healthcare Analytics Research and Training (LKS-CHART) (M.M.), Li Ka Shing Knowledge Institute, Toronto, ON, Canada (A.L.); St. Michael's Hospital, Toronto, ON, Canada (P.D.); Clinical Epidemiology Program, Ottawa Hospital Research Institute, The Ottawa Hospital; School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa; Institute of Clinical and Evaluative Sciences (ICES UOttawa), ON, Canada (K.T.); Institute of Health Policy, Management, and Evaluation (J.S.H., M.M., A.L.), Dalla Lana School of Public Health (K.E.T.), Leslie Dan Faculty of Pharmacy (J.S.H., M.M.), Division of Neurology (D.J.G.), and Department of Medicine (M.M., P.D., A.L., D.J.G.), University of Toronto, ON, Canada; Department of Public Health Sciences and Center for Healthcare Policy and Research, University of California, Davis, CA (J.S.H.); Division of Neurology, Department of Medicine, McMaster University, Hamilton, ON, Canada (M.S.); and Division of Neurology, Department of Medicine, Hurvitz Brain Sciences Program, and Regional Stroke Centre, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, ON, Canada (D.J.G.).

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http://dx.doi.org/10.1161/STROKEAHA.115.011979DOI Listing
September 2016

Post-stroke depression, obstructive sleep apnea, and cognitive impairment: Rationale for, and barriers to, routine screening.

Int J Stroke 2016 07 12;11(5):509-18. Epub 2016 Apr 12.

University of Toronto, Toronto, Canada Hurvitz Brain Sciences Research Program, Toronto, Canada Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Canada.

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http://dx.doi.org/10.1177/1747493016641968DOI Listing
July 2016

Why Clinicians Prognosticate Stroke Patients Poorly: Results from the Clinician Judgment versus Risk Score to Predict Stroke Outcomes Randomized Study.

J Stroke Cerebrovasc Dis 2016 Jun 14;25(6):1349-54. Epub 2016 Mar 14.

Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Stroke Research Unit, Mobility Program, St. Michael's Hospital, Toronto, Canada; Department of Medicine, Institute of Health Policy, Management and Education, University of Toronto, Toronto, Canada; Cardiovascular Research Program, Institute for Clinical Evaluative Sciences, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.01.024DOI Listing
June 2016

Integrating a Smartphone-Based Self-Management System into Usual Care of Advanced CKD.

Clin J Am Soc Nephrol 2016 06 12;11(6):1054-62. Epub 2016 May 12.

Medicine, Nephrology, Lunenfeld-Tanenbaum Research Institute and Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada;

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http://dx.doi.org/10.2215/CJN.10681015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891756PMC
June 2016

Validating a Pragmatic Approach to Cognitive Screening in Stroke Prevention Clinics Using the Montreal Cognitive Assessment.

Stroke 2016 Mar 28;47(3):807-13. Epub 2016 Jan 28.

From the Departments of Medicine (Neurology) (R.H.S., B.J.M.) and Psychiatry (K.L.L., N.H.), and Dalla Lana School of Public Health (K.E.T.), University of Toronto, Toronto, ON, Canada; Departments of Medicine (Neurology) (R.H.S., M.L.C., B.J.M.) and Psychiatry (K.L.L., N.H.), and Hurvitz Brain Sciences Research Program (R.H.S., K.L.L., B.J.M, N.H.), Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Toronto, ON, Canada (R.H.S., K.L.L.); University of Toronto Stroke Program, Toronto, ON, Canada (R.H.S., M.L.C.); Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (E.E.S.); Department of Medicine (Neurology), Hamilton General Hospital, Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada (D.J.S.); and St. Michael's Hospital, Applied Health Research Centre of the Li Ka Shing Knowledge Institute, Toronto, ON Canada (A.C., K.E.T.).

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http://stroke.ahajournals.org/content/early/2016/01/28/STROK
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http://stroke.ahajournals.org/lookup/doi/10.1161/STROKEAHA.1
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http://dx.doi.org/10.1161/STROKEAHA.115.011036DOI Listing
March 2016

Thyroid cancer patient perceptions of radioactive iodine treatment choice: Follow-up from a decision-aid randomized trial.

Cancer 2015 Oct 20;121(20):3717-26. Epub 2015 Jul 20.

Department of Otolaryngology and Head and Neck Surgery, University Health Network/University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1002/cncr.29548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832354PMC
October 2015

Risk factors, practice variation and hematological outcomes of children identified with non-anemic iron deficiency following screening in primary care setting.

Paediatr Child Health 2015 Aug-Sep;20(6):302-6

Pediatrics Outcomes Research Team, Division of Pediatric Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario ; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario ; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario ; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario ; Child Health Evaluative Sciences, Hospital for Sick Children Research Institute, Toronto, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578469PMC
http://dx.doi.org/10.1093/pch/20.6.302DOI Listing
October 2015

Inhaled nitric oxide as adjunctive therapy for severe malaria: a randomized controlled trial.

Malar J 2015 Oct 29;14:421. Epub 2015 Oct 29.

Sandra Rotman Centre for Global Health, MaRS Centre, University of Toronto, 101 College St TMDT 10-360A, Toronto, ON, M5G 1L7, Canada.

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http://dx.doi.org/10.1186/s12936-015-0946-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625637PMC
October 2015

Using a systematic review in clinical decision making: a pilot parallel, randomized controlled trial.

Implement Sci 2015 Aug 15;10:118. Epub 2015 Aug 15.

Faculty of Medicine, Keenan Research Centre, Li Ka Shing Knowledge Institute, University of Toronto, St. Michael's Hospital, 30 Bond Street, Toronto, Canada.

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http://implementationscience.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s13012-015-0303-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542122PMC
August 2015

Common Design and Analysis Issues in Clinical Trials.

Authors:
Kevin E Thorpe

J Rheumatol 2015 Jul;42(7):1075-7

Dalla Lana School of Public Health, University of Toronto; Head of Biostatistics, Applied Health Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.150461
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http://dx.doi.org/10.3899/jrheum.150461DOI Listing
July 2015

Decision aid on radioactive iodine treatment for early stage papillary thyroid cancer: update to study protocol with follow-up extension.

Trials 2015 Jul 14;16:302. Epub 2015 Jul 14.

Department of Otolaryngology Head and Neck Surgery, University Health Network and University of Toronto, Wharton Head and Neck Centre 3-952, 610 University Avenue, Toronto, Ontario, Canada, M5G 2M9.

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http://dx.doi.org/10.1186/s13063-015-0819-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501089PMC
July 2015

An internal pilot study for a randomized trial aimed at evaluating the effectiveness of iron interventions in children with non-anemic iron deficiency: the OptEC trial.

Trials 2015 Jul 14;16:303. Epub 2015 Jul 14.

Division of Pediatric Medicine, Department of Pediatrics, Pediatrics Outcomes Research Team, The Hospital for Sick Children, Room 109708, 10th Floor, 555 University Avenue, M5G 1X8, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/s13063-015-0829-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501099PMC
July 2015

The PRECIS-2 tool: designing trials that are fit for purpose.

BMJ 2015 May 8;350:h2147. Epub 2015 May 8.

Centre for Studies in Family Medicine, Schulich School of Medicine & Dentistry, Western University, Western Centre for Public Health and Family Medicine, London, ON N6A 3K7, Canada.

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http://dx.doi.org/10.1136/bmj.h2147DOI Listing
May 2015

Atrial premature beats predict atrial fibrillation in cryptogenic stroke: results from the EMBRACE trial.

Stroke 2015 Apr 19;46(4):936-41. Epub 2015 Feb 19.

From the Division of Neurology (D.J.G.), Department of Medicine (D.J.G., P.D., M.S., M.M.), and Dalla Lana School of Public Health (K.E.T.), University of Toronto, Toronto, Ontario, Canada; University of Toronto Stroke Program, Toronto, Ontario, Canada (D.J.G.); Division of Neurology, Department of Medicine, and the Hurvitz Brain Sciences Program, Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, Ontario, Canada (D.J.G.); Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Toronto, Ontario, Canada (D.J.G.); Applied Health Research Centre (AHRC), Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada (M.M., V.P., K.E.T.); and Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (J.S.H.).

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http://dx.doi.org/10.1161/STROKEAHA.115.008714DOI Listing
April 2015

The effect of time to defibrillation and targeted temperature management on functional survival after out-of-hospital cardiac arrest.

Resuscitation 2014 Nov 12;85(11):1623-8. Epub 2014 Aug 12.

Rescu, Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada; Institute of Medical Science, Department of Medicine, University of Toronto, Toronto, ON, Canada; Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.resuscitation.2014.07.010DOI Listing
November 2014

iPad technology for home rehabilitation after stroke (iHOME): a proof-of-concept randomized trial.

Int J Stroke 2014 Oct 7;9(7):956-62. Epub 2014 Jul 7.

Stroke Outcomes Research Centre, Division of Neurology, St. Michael's Hospital, University of Toronto, Toronto, Canada; Neuroscience Research Program, Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1111/ijs.12328DOI Listing
October 2014

Effect of a postdischarge virtual ward on readmission or death for high-risk patients: a randomized clinical trial.

JAMA 2014 Oct;312(13):1305-12

Department of Medicine, University of Toronto, Toronto, Ontario, Canada2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto4Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto5Institute for Clinical Evaluati.

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http://www.gim.utoronto.ca/Assets/GIM+Digital+Assets/VW+JAMA
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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
Publisher Site
http://dx.doi.org/10.1001/jama.2014.11492DOI Listing
October 2014

Non-Western immigrant children have lower 25-hydroxyvitamin D than children from Western families.

Public Health Nutr 2014 Jul 24;17(7):1547-54. Epub 2013 May 24.

1Department of Nutritional Sciences,University of Toronto,Toronto,ON,Canada.

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http://dx.doi.org/10.1017/S1368980013001328DOI Listing
July 2014

Atrial fibrillation in patients with cryptogenic stroke.

N Engl J Med 2014 Jun;370(26):2467-77

From the Division of Neurology (D.J.G.), Department of Medicine (D.J.G., P.D., A.L., M.S., J.A.B., L.K.C., D.S., M. Mehdiratta, K.B., M.K.K.), and Dalla Lana School of Public Health (K.E.T.), University of Toronto, the University of Toronto Stroke Program (D.J.G.), Division of Neurology, Department of Medicine, and Brain Sciences Program, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute (D.J.G., R.A.), the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (D.J.G.), and the Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital (V.P., K.E.T., J.H., H.V., A.L., M. Mamdani), Toronto, McMaster University, Hamilton, ON (M.S., D.J.S.), McGill University, Montreal (R.C.), University of Alberta, Edmonton (A.S., B.B.), Western University, London, ON (V.H., J.D.S.), Department of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB (S.B.C.), University of British Columbia, Vancouver (P.T., S.Y.), Queen's University, Kingston, ON (A.J.), Thunder Bay Regional Health Sciences Centre, Thunder Bay, ON (D.H.), Université Laval, Quebec City (S.V.), and Vancouver Island Health Research Centre, Victoria, BC (A.P.) - all in Canada; and the National University of Ireland, Galway (M.O.).

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http://dx.doi.org/10.1056/NEJMoa1311376DOI Listing
June 2014

Parathyroid hormone as a functional indicator of vitamin D sufficiency in children.

JAMA Pediatr 2014 Apr;168(4):383-5

Pediatrics Outcomes Research Team, Division of Paediatric Medicine, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamapediatrics.2013.5379DOI Listing
April 2014

Feasibility study on the Model Schools Paediatric Health Initiative pilot project.

Paediatr Child Health 2013 Aug;18(7):361-6

Applied Health Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Toronto, Ontario ; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario ; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804636PMC
August 2013

JURaSSiC: accuracy of clinician vs risk score prediction of ischemic stroke outcomes.

Neurology 2013 Jul 28;81(5):448-55. Epub 2013 Jun 28.

Stroke Outcomes Research Unit, Division of Neurology, Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Canada.

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http://sorcan.ca/papers/WNL205250.pdf
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http://www.neurology.org/cgi/doi/10.1212/WNL.0b013e31829d874
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http://dx.doi.org/10.1212/WNL.0b013e31829d874eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776534PMC
July 2013

Modifiable determinants of serum 25-hydroxyvitamin D status in early childhood: opportunities for prevention.

JAMA Pediatr 2013 Mar;167(3):230-5

Department of Pediatrics, St Michael’s Hospital, 30 Bond St, 15-014 Cardinal Carter, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/2013.jamapediatrics.226DOI Listing
March 2013

Nurse- vs nomogram-directed glucose control in a cardiovascular intensive care unit.

Am J Crit Care 2012 Jul;21(4):270-8

Pharmacy Department, Critical Care Department at St Michael's Hospital, Toronto, Canada.

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http://dx.doi.org/10.4037/ajcc2012713DOI Listing
July 2012

Fabry's disease: a prospective multicenter cohort study in young adults with cryptogenic stroke.

Int J Stroke 2012 Apr 20;7(3):265-73. Epub 2012 Jan 20.

Departments of Medicine and Health Policy, Management and Evaluation, Division of Neurology, Stroke Outcomes Research Unit, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/j.1747-4949.2011.00734.xDOI Listing
April 2012

Six-year follow-up of a randomised controlled trial examining hospital versus home-based exercise training after coronary artery bypass graft surgery.

Heart 2011 Jul 10;97(14):1169-74. Epub 2011 May 10.

Department of Medicine, University of Illinois College of Medicine at Chicago, Section of Health Promotion Research, Chicago, Illinois, USA.

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http://heart.bmj.com/cgi/doi/10.1136/hrt.2010.202036
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July 2011

Blood transfusion and cardiac surgery.

JAMA 2011 Jan;305(4):357-8; author reply 358-9

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http://dx.doi.org/10.1001/jama.2011.14DOI Listing
January 2011

Office-based intervention to reduce bottle use among toddlers: TARGet Kids! Pragmatic, randomized trial.

Pediatrics 2010 Aug 12;126(2):e343-50. Epub 2010 Jul 12.

Applied Health Research Centre, Li Ka Shing Knowledge Institute, Department of Pediatrics, St Michael's Hospital, Toronto, Ontario, Canada.

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http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2
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http://dx.doi.org/10.1542/peds.2009-3583DOI Listing
August 2010

Effectiveness of virtual reality using Wii gaming technology in stroke rehabilitation: a pilot randomized clinical trial and proof of principle.

Stroke 2010 Jul 27;41(7):1477-84. Epub 2010 May 27.

Division of Neurology, Departments of Medicine and Health Policy Management and Evaluation and Institute for Clinical Evaluative Sciences, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Dalla Lana, School of Public Health, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1161/STROKEAHA.110.584979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879973PMC
July 2010

Improving the diagnosis of acute heart failure using a validated prediction model.

J Am Coll Cardiol 2009 Oct;54(16):1515-21

Department of Medicine, Saint Michael's Hospital, 30 Bond Street, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2009.05.065DOI Listing
October 2009

A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers.

CMAJ 2009 May 16;180(10):E47-57. Epub 2009 Apr 16.

Dalla Lana School of Public Health, University of Toronto, 6th floor, Health Sciences Building, 155 College St., Toronto ON M5T 3M7.

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http://dx.doi.org/10.1503/cmaj.090523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679824PMC
May 2009

Does this patient have bacterial peritonitis or portal hypertension? How do I perform a paracentesis and analyze the results?

JAMA 2008 Mar;299(10):1166-78

Division of Geriatric Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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March 2008

What type of urinary incontinence does this woman have?

JAMA 2008 Mar;299(12):1446-56

Division of Geriatrics, and Knowledge Translation Program, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1001/jama.299.12.1446DOI Listing
March 2008

How do I perform a lumbar puncture and analyze the results to diagnose bacterial meningitis?

JAMA 2006 Oct;296(16):2012-22

Division of General Internal Medicine, University of Calgary, Alberta.

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http://dx.doi.org/10.1001/jama.296.16.2012DOI Listing
October 2006

Accuracy of physician self-assessment compared with observed measures of competence: a systematic review.

JAMA 2006 Sep;296(9):1094-102

Knowledge Translation Program of the Li Ka Shing Knowledge Institute at St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jama.296.9.1094DOI Listing
September 2006

The effectiveness of hydroxychloroquine in patients with type 2 diabetes mellitus who are refractory to sulfonylureas--a randomized trial.

Diabetes Res Clin Pract 2002 Mar;55(3):209-19

Department of Medicine, McMaster University, Room 3V38, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5.

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http://dx.doi.org/10.1016/s0168-8227(01)00325-4DOI Listing
March 2002

Survival comparison between hemodialysis and peritoneal dialysis based on matched doses of delivered therapy.

J Am Soc Nephrol 2002 Jan;13 Suppl 1:S48-52

Department of Physiology, Himalayan Institute Hospital Trust, Dehradun, U.P., India.

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January 2002