Publications by authors named "Keun Hur"

50Publications

Epigenetic Associations between lncRNA/circRNA and miRNA in Hepatocellular Carcinoma.

Cancers (Basel) 2020 Sep 14;12(9). Epub 2020 Sep 14.

Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

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http://dx.doi.org/10.3390/cancers12092622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565033PMC
September 2020

The Roles of Hypoxia-Inducible Factors and Non-Coding RNAs in Gastrointestinal Cancer.

Genes (Basel) 2019 12 4;10(12). Epub 2019 Dec 4.

Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.

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http://dx.doi.org/10.3390/genes10121008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947354PMC
December 2019

High expression of microRNA-199a-5p is associated with superior clinical outcomes in patients with locally advanced rectal cancer.

J Cancer Res Clin Oncol 2020 Jan 28;146(1):105-115. Epub 2019 Nov 28.

Department of Oncology/Hematology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University Cancer Research Institute, Kyungpook National University, 807 Hogukno, Buk-gu, Daegu, 41404, Republic of Korea.

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http://dx.doi.org/10.1007/s00432-019-03099-4DOI Listing
January 2020

Epigenetic Alterations of Heat Shock Proteins (HSPs) in Cancer.

Int J Mol Sci 2019 Sep 25;20(19). Epub 2019 Sep 25.

Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.

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http://dx.doi.org/10.3390/ijms20194758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801855PMC
September 2019

Circulating miR-203 derived from metastatic tissues promotes myopenia in colorectal cancer patients.

J Cachexia Sarcopenia Muscle 2019 06 25;10(3):536-548. Epub 2019 Mar 25.

Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1002/jcsm.12403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596405PMC
June 2019

Potential Implications of Long Noncoding RNAs in Autoimmune Diseases.

Immune Netw 2019 Feb 25;19(1):e4. Epub 2019 Feb 25.

Division of Rheumatology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University College of Medicine, Daegu 41931, Korea.

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http://dx.doi.org/10.4110/in.2019.19.e4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399094PMC
February 2019

The Epigenetic Regulation of HCC Metastasis.

Int J Mol Sci 2018 Dec 10;19(12). Epub 2018 Dec 10.

Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.

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http://dx.doi.org/10.3390/ijms19123978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321007PMC
December 2018

Circulating exosomal noncoding RNAs as prognostic biomarkers in human hepatocellular carcinoma.

Int J Cancer 2019 03 3;144(6):1444-1452. Epub 2018 Dec 3.

Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, South Korea.

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http://doi.wiley.com/10.1002/ijc.31931
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http://dx.doi.org/10.1002/ijc.31931DOI Listing
March 2019

Clinical significance of microRNA-21 expression in disease progression of patients with hepatocellular carcinoma.

Biomark Med 2018 10 7;12(10):1105-1114. Epub 2018 Sep 7.

Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.

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https://www.futuremedicine.com/doi/10.2217/bmm-2018-0096
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http://dx.doi.org/10.2217/bmm-2018-0096DOI Listing
October 2018

SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency.

Cell Death Dis 2018 08 30;9(9):893. Epub 2018 Aug 30.

Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu, 41566, Republic of Korea.

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http://dx.doi.org/10.1038/s41419-018-0920-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117269PMC
August 2018

Comparison of acoustic radiation force impulse elastography and transient elastography for prediction of hepatocellular carcinoma recurrence after radiofrequency ablation.

Eur J Gastroenterol Hepatol 2018 10;30(10):1230-1236

Department of Biostatistics, School of Medicine, Medical Research Collaboration Center in Kyungpook National University, Kyungpook National University, Daegu, South Korea.

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http://Insights.ovid.com/crossref?an=00042737-201810000-0001
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http://dx.doi.org/10.1097/MEG.0000000000001170DOI Listing
October 2018

Clinical significance of lncRNA-ATB expression in human hepatocellular carcinoma.

Oncotarget 2017 Oct 20;8(45):78588-78597. Epub 2017 Sep 20.

Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.

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http://dx.doi.org/10.18632/oncotarget.21094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667984PMC
October 2017

Tenofovir, entecavir, and lamivudine in patients with severe acute exacerbation and hepatic decompensation of chronic hepatitis B.

Dig Liver Dis 2018 Feb 28;50(2):163-167. Epub 2017 Oct 28.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu, Republic of Korea.

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http://dx.doi.org/10.1016/j.dld.2017.10.002DOI Listing
February 2018

Long-term follow-up of complete remission of advanced hepatocellular carcinoma following sorafenib therapy: A case report.

Oncol Lett 2017 Oct 22;14(4):4853-4856. Epub 2017 Aug 22.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu 41940, Republic of Korea.

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http://dx.doi.org/10.3892/ol.2017.6788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649582PMC
October 2017

High level of viral microRNA-BART20-5p expression is associated with worse survival of patients with Epstein-Barr virus-associated gastric cancer.

Oncotarget 2017 Feb;8(9):14988-14994

Department of Oncology/Hematology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Kyungpook National University Cancer Research Institute, Kyungpook National University, Daegu, South Korea.

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http://dx.doi.org/10.18632/oncotarget.14744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362460PMC
February 2017

Using transient elastography to predict hepatocellular carcinoma recurrence after radiofrequency ablation.

J Gastroenterol Hepatol 2017 May;32(5):1079-1086

Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine Kyungpook National University, Daegu, South Korea.

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http://dx.doi.org/10.1111/jgh.13644DOI Listing
May 2017

Gastric Carcinogenesis in the miR-222/221 Transgenic Mouse Model.

Cancer Res Treat 2017 Jan 23;49(1):150-160. Epub 2016 Jun 23.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2015.462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266385PMC
January 2017

MAL and TMEM220 are novel DNA methylation markers in human gastric cancer.

Biomarkers 2017 Feb 22;22(1):35-44. Epub 2016 Sep 22.

a Cancer Research Institute , Seoul National University College of Medicine , Seoul , Korea.

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http://dx.doi.org/10.1080/1354750X.2016.1201542DOI Listing
February 2017

Clinical significance of fibroblast growth factor receptor 2 expression in patients with residual rectal cancer after preoperative chemoradiotherapy: relationship with KRAS or BRAF mutations and MSI status.

Tumour Biol 2016 Aug 30;37(8):10209-18. Epub 2016 Jan 30.

Department of Pathology, Kyungpook National University Medical Center, 807 Hogukno, Buk-gu, Daegu, 41404, Republic of Korea.

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http://dx.doi.org/10.1007/s13277-016-4899-zDOI Listing
August 2016

Circulating microRNA-203 predicts prognosis and metastasis in human colorectal cancer.

Gut 2017 04 23;66(4):654-665. Epub 2015 Dec 23.

Center for Gastrointestinal Cancer Research, Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1136/gutjnl-2014-308737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919275PMC
April 2017

Identification of a metastasis-specific MicroRNA signature in human colorectal cancer.

J Natl Cancer Inst 2015 Mar 6;107(3). Epub 2015 Feb 6.

Center for Gastrointestinal Research and Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, TX (KH, YT, YO, CRB, AG); National Cancer Institute, National Institutes of Health, Bethesda, MD (AJS, CCH).

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http://dx.doi.org/10.1093/jnci/dju492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334826PMC
March 2015

MicroRNAs: promising biomarkers for diagnosis and therapeutic targets in human colorectal cancer metastasis.

Authors:
Keun Hur

BMB Rep 2015 Apr;48(4):217-22

Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 700-842, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436857PMC
http://dx.doi.org/10.5483/bmbrep.2015.48.4.007DOI Listing
April 2015

Metastasis-associated long non-coding RNA drives gastric cancer development and promotes peritoneal metastasis.

Carcinogenesis 2014 Dec 3;35(12):2731-9. Epub 2014 Oct 3.

Gastrointestinal Cancer Research Laboratory, Division of Gastroenterology, Department of Internal Medicine, Charles A. Sammons Cancer Center and Baylor Research Institute, Baylor University Medical Center, 3500 Gaston Avenue, Suite H-250, Dallas, TX 75246, USA and

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http://dx.doi.org/10.1093/carcin/bgu200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247518PMC
December 2014

MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1.

Gut 2015 Feb 28;64(2):203-14. Epub 2014 May 28.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea Departments of Surgery, Seoul National University College of Medicine, Seoul, Korea.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2013-306640
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http://dx.doi.org/10.1136/gutjnl-2013-306640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384419PMC
February 2015

Serum miR-200c is a novel prognostic and metastasis-predictive biomarker in patients with colorectal cancer.

Ann Surg 2014 Apr;259(4):735-43

*Gastrointestinal Cancer Research Laboratory, Division of Gastroenterology, Department of Internal Medicine, Charles A. Sammons Cancer Center and Baylor Research Institute, Baylor University Medical Center, Dallas, TX †Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Graduate School of Medicine, Mie University, Mie, Japan.

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http://dx.doi.org/10.1097/SLA.0b013e3182a6909dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032090PMC
April 2014

Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis.

Gut 2014 Apr 23;63(4):635-46. Epub 2013 May 23.

Gastrointestinal Cancer Research Laboratory, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, , Dallas, Texas, USA.

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http://dx.doi.org/10.1136/gutjnl-2012-304219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884067PMC
April 2014

Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer.

J Natl Cancer Inst 2013 Jun 23;105(12):849-59. Epub 2013 May 23.

Gastrointestinal Cancer Research Laboratory, Division of Gastroenterology, Department of Internal Medicine, Charles A. Sammons Cancer Center and Baylor Research Institute, Baylor University Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1093/jnci/djt101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687369PMC
June 2013

The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer.

PLoS One 2012 3;7(10):e46684. Epub 2012 Oct 3.

Gastrointestinal Cancer Research Laboratory, Baylor Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046684PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463512PMC
May 2013

Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family.

Carcinogenesis 2012 Dec 15;33(12):2441-9. Epub 2012 Sep 15.

GI Cancer Research Laboratory, Baylor University Medical Center, 3500 Gaston Avenue, 250 Hoblitzelle, Dallas, TX 75246, USA.

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http://dx.doi.org/10.1093/carcin/bgs286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510738PMC
December 2012

MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis.

Gut 2013 Sep 26;62(9):1315-26. Epub 2012 Jun 26.

Gastrointestinal Cancer Research Laboratory, Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, TX 75246, USA.

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http://dx.doi.org/10.1136/gutjnl-2011-301846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787864PMC
September 2013

Up-regulated expression of sulfatases (SULF1 and SULF2) as prognostic and metastasis predictive markers in human gastric cancer.

J Pathol 2012 Sep 18;228(1):88-98. Epub 2012 Jul 18.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1002/path.4055DOI Listing
September 2012

Dissemination of free cancer cells from the gastric lumen and from perigastric lymphovascular pedicles during radical gastric cancer surgery.

Ann Surg Oncol 2011 Oct 1;18(10):2818-25. Epub 2011 Apr 1.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1245/s10434-011-1620-8DOI Listing
October 2011

The antitumor effect of a thermosensitive polymeric hydrogel containing paclitaxel in a peritoneal carcinomatosis model.

Invest New Drugs 2012 Feb 29;30(1):1-7. Epub 2010 Jul 29.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

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http://link.springer.com/10.1007/s10637-010-9499-y
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http://dx.doi.org/10.1007/s10637-010-9499-yDOI Listing
February 2012

Gene expression profiling of human gastrointestinal stromal tumors according to its malignant potential.

Dig Dis Sci 2010 Sep 27;55(9):2561-7. Epub 2010 Jan 27.

Cancer Research Institute, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110-744, Republic of Korea.

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http://dx.doi.org/10.1007/s10620-009-1061-4DOI Listing
September 2010

Suppression of in vivo tumor growth by using a biodegradable thermosensitive hydrogel polymer containing chemotherapeutic agent.

Invest New Drugs 2010 Jun 22;28(3):284-90. Epub 2009 Apr 22.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

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http://link.springer.com/10.1007/s10637-009-9253-5
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http://dx.doi.org/10.1007/s10637-009-9253-5DOI Listing
June 2010

Expression of Krüppel-like factor 5 in human gastric carcinomas.

J Cancer Res Clin Oncol 2008 Feb 11;134(2):163-7. Epub 2007 Jul 11.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1007/s00432-007-0265-2DOI Listing
February 2008

Tumor specificity and in vivo targeting of an antibody against exon 9 deleted E-cadherin in gastric cancer.

J Cancer Res Clin Oncol 2007 Dec 19;133(12):987-94. Epub 2007 Jun 19.

Cancer Research Institute, Seoul National University, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Republic of Korea.

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http://dx.doi.org/10.1007/s00432-007-0246-5DOI Listing
December 2007

Expression of gastrin and its receptor in human gastric cancer tissues.

J Cancer Res Clin Oncol 2006 Feb 14;132(2):85-91. Epub 2005 Oct 14.

Cancer Research Institute, Seoul National University College of Medicine, Chongno-gu, Seoul, 110-744, Republic of Korea.

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http://dx.doi.org/10.1007/s00432-005-0043-yDOI Listing
February 2006

Growth effect of gastrin on gastric cancer and its clinical implications for gastric cancer surgery.

Oncol Rep 2005 Aug;14(2):383-8

Department of Surgery, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu, Seoul 110-744, Korea.

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August 2005

Expression of chemokine receptors in human gastric cancer.

Tumour Biol 2005 Mar-Apr;26(2):65-70. Epub 2005 May 3.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

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http://search.proquest.com/openview/d19d73902d2dd746558123c2
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http://www.karger.com/doi/10.1159/000085587
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http://dx.doi.org/10.1159/000085587DOI Listing
June 2005

Aberrant methylation of the specific CpG island portion regulates cyclooxygenase-2 gene expression in human gastric carcinomas.

Biochem Biophys Res Commun 2003 Oct;310(3):844-51

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2003.09.095DOI Listing
October 2003