Kerstin Jurk

Kerstin Jurk

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Kerstin Jurk

Kerstin Jurk

Publications by authors named "Kerstin Jurk"

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CD133 bone marrow stem cells (BMSC) control platelet activation - Role of ectoNTPDase-1 (CD39).

Blood Cells Mol Dis 2019 Jul 27;77:142-148. Epub 2019 Apr 27.

Center of Visceral Medicine, Department of General and Visceral Surgery, Protestant Hospital of Bethel Foundation, Bielefeld, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2019.04.012DOI Listing
July 2019

The Direct Thrombin Inhibitors Dabigatran and Lepirudin Inhibit GPIbα-Mediated Platelet Aggregation.

Thromb Haemost 2019 Apr 20. Epub 2019 Apr 20.

Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.

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http://dx.doi.org/10.1055/s-0039-1685139DOI Listing
April 2019

Platelet Activation by Antiphospholipid Antibodies Depends on Epitope Specificity and is Prevented by mTOR Inhibitors.

Thromb Haemost 2019 Apr 24. Epub 2019 Apr 24.

Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany.

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http://dx.doi.org/10.1055/s-0039-1685453DOI Listing
April 2019

New Insights into Platelet Signalling Pathways by Functional and Proteomic Approaches.

Hamostaseologie 2018 Nov 19. Epub 2018 Nov 19.

Center for Thrombosis and Hemostasis (CTH), University Medical Center, Johannes-Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1055/s-0038-1675356DOI Listing
November 2018

Phospholipase D1 regulation of TNF-alpha protects against responses to LPS.

Sci Rep 2018 Jul 3;8(1):10006. Epub 2018 Jul 3.

Department of Vascular and Endovascular Surgery, Heinrich-Heine-University University Medical Center, Moorenstraße.5, 40225, Düsseldorf, Germany.

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http://dx.doi.org/10.1038/s41598-018-28331-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030188PMC
July 2018

Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets.

Nitric Oxide 2018 06 14;76:71-80. Epub 2018 Mar 14.

University Medical Center Mainz, Center for Thrombosis and Hemostasis (CTH), Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.niox.2018.03.008DOI Listing
June 2018

Antiplatelet Agents and Anticoagulants in Patients with Chronic Kidney Disease - from Pathophysiology to Clinical Practice.

Curr Pharm Des 2017 ;23(9):1366-1376

Center for Thrombosis and Hemostasis, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131 Mainz. Germany.

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http://dx.doi.org/10.2174/1381612822666161205112156DOI Listing
April 2018

Platelet granules - secretory and secretive.

Authors:
Kerstin Jurk

Hamostaseologie 2017 Aug 21;37(3):208-210. Epub 2016 Sep 21.

PD Dr. rer. nat. Kerstin Jurk Center for Thrombosis and Hemostasis (CTH) University Medical Center Mainz Langenbeckstr. 1, 55131 Mainz, Germany E-Mail:

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http://dx.doi.org/10.5482/HAMO-16-07-0023DOI Listing
August 2017

Hypoxia impairs agonist-induced integrin αβ activation and platelet aggregation.

Sci Rep 2017 08 8;7(1):7621. Epub 2017 Aug 8.

Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Langenbeckstrasse 1, Building 708, 55131, Mainz, Germany.

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http://www.nature.com/articles/s41598-017-07988-x
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http://dx.doi.org/10.1038/s41598-017-07988-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548784PMC
August 2017

Direct oral anticoagulants in patients with chronic kidney disease: patient selection and special considerations.

Int J Nephrol Renovasc Dis 2017 12;10:135-143. Epub 2017 Jun 12.

Cardiopraxis Mainz, Gerinnungsambulanz, MED Facharztzentrum, Mainz, Germany.

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http://dx.doi.org/10.2147/IJNRD.S105771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473496PMC
June 2017

Taking the stock of granule cargo: Platelet releasate proteomics.

Platelets 2017 Mar 8;28(2):119-128. Epub 2016 Dec 8.

a Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V ., Dortmund , Germany.

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http://dx.doi.org/10.1080/09537104.2016.1254762DOI Listing
March 2017

Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B.

Thromb Haemost 2017 02 12;117(3):556-569. Epub 2017 Jan 12.

Kerstin Jurk, Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Langenbeckstr. 1, 55131 Mainz, Germany, Tel.: +49 6131 178278, Fax: +49 6131 176238, E-mail:

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http://dx.doi.org/10.1160/TH16-07-0515DOI Listing
February 2017

Hepatic Overexpression of Soluble Urokinase Receptor (uPAR) Suppresses Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR-/-) Mice.

PLoS One 2015 27;10(8):e0131854. Epub 2015 Aug 27.

Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany; Department of Health Services Sciences, Faculty of Medicine and Health Sciences, University of Oldenburg, Oldenburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131854PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551736PMC
May 2016

What can proteomics tell us about platelets?

Circ Res 2014 Mar;114(7):1204-19

From the Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany (J.M.B., A.S., R.P.Z); Institut für Klinische Biochemie und Pathobiochemie, Universitätsklinikum Würzburg, Würzburg, Germany (S.G.); Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia (S.G.); Centre for Cardiovascular Sciences, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom (S.P.W.); Center for Thrombosis and Hemostasis, Universitätsklinikum der Johannes Gutenberg-Universität Mainz, Mainz, Germany (K.J., U.W.); Medizinisches Proteom Center, Ruhr Universität Bochum, Bochum, Germany (A.S.); Department of Chemistry, College of Physical Sciences, University of Aberdeen, Aberdeen, Scotland, United Kingdom (A.S.); and Department of Biochemistry, CARIM, Maastricht University, Maastricht, The Netherlands (J.W.M.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.301598DOI Listing
March 2014

Role for the fibrinogen-binding proteins coagulase and Efb in the Staphylococcus aureus-Candida interaction.

Int J Med Microbiol 2013 Jul 13;303(5):230-8. Epub 2013 Mar 13.

Institute of Medical Microbiology, University Hospital of Münster, D-48149 Münster, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2013.02.011DOI Listing
July 2013

Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases.

Arterioscler Thromb Vasc Biol 2012 Aug 26;32(8):1979-90. Epub 2012 Apr 26.

Department of Anesthesiology and Intensive Care, Experimental and Clinical Hemostasis, University of Muenster, Mendelstr 11, 48149 Muenster, Germany.

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http://dx.doi.org/10.1161/ATVBAHA.112.246249DOI Listing
August 2012

Activated monocytes capture platelets for heterotypic association in patients with severe carotid artery stenosis.

Thromb Haemost 2010 Jun 29;103(6):1193-202. Epub 2010 Mar 29.

Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostaseology, University Hospital, Muenster, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH09-09-0620
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http://dx.doi.org/10.1160/TH09-09-0620DOI Listing
June 2010

Novel integrin-dependent platelet malfunction in siblings with leukocyte adhesion deficiency-III (LAD-III) caused by a point mutation in FERMT3.

Thromb Haemost 2010 May 9;103(5):1053-64. Epub 2010 Mar 9.

Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University-Hospital of Münster, Münster, Germany.

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http://dx.doi.org/10.1160/TH09-10-0689DOI Listing
May 2010

Acute uremia but not renal inflammation attenuates aseptic acute lung injury: a critical role for uremic neutrophils.

J Am Soc Nephrol 2006 Nov 11;17(11):3124-31. Epub 2006 Oct 11.

Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Universitätsklinikum Münster, Münster, Germany.

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http://dx.doi.org/10.1681/ASN.2006040358DOI Listing
November 2006

IL-4 enhances hypoxia induced HIF-1alpha protein levels in human transformed intestinal cells.

FEBS Lett 2006 Nov 3;580(27):6399-404. Epub 2006 Nov 3.

Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Universitätsklinikum Münster, Germany.

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http://dx.doi.org/10.1016/j.febslet.2006.10.053DOI Listing
November 2006

Optimized flow cytometric analysis of endothelial progenitor cells in peripheral blood.

J Immunoassay Immunochem 2006 ;27(1):77-88

Institute of Anatomy, University-Hospital of Münster, Münster, Germany.

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http://dx.doi.org/10.1080/15321810500403789DOI Listing
March 2006

Platelets: physiology and biochemistry.

Semin Thromb Hemost 2005 ;31(4):381-92

Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University-Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1055/s-2005-916671DOI Listing
December 2005

Intercellular adhesion molecule-1 inhibition attenuates neurologic and hepatic damage after resuscitation in mice.

Anesthesiology 2005 Dec;103(6):1149-55

Department of Anesthesiology and IZKF, University Hospital Münster, University of Münster, Vesaliusweg 2-4, 48149 Münster, Germany.

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December 2005

Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells.

Blood 2005 Apr 14;105(7):2955-62. Epub 2004 Dec 14.

Institute of Experimental Dermatology, Integrated Functional Genomics, and the Interdisciplinary Clinical Research Center, University Hospital Muenster, University of Muenster, Röntgenstrasse 21, 48149 Muenster, Germany.

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http://www.bloodjournal.org/content/105/7/2955.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-07-25
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http://dx.doi.org/10.1182/blood-2004-07-2520DOI Listing
April 2005

Platelets in patients with acute ischemic stroke are exhausted and refractory to thrombin, due to cleavage of the seven-transmembrane thrombin receptor (PAR-1).

Thromb Haemost 2004 Feb;91(2):334-44

Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University-Hospital of Münster, Münster, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH03-01-0044
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http://dx.doi.org/10.1160/TH03-01-0044DOI Listing
February 2004

Thrombospondin-1 mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): an alternative/backup mechanism to von Willebrand factor.

FASEB J 2003 Aug 17;17(11):1490-2. Epub 2003 Jun 17.

Department of Anaesthesiology and Intensive Care, Experimental and Clinical Haemostasis, University-Hospital Münster, Mendelstr. 11, 48149 Münster, Germany.

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http://dx.doi.org/10.1096/fj.02-0830fjeDOI Listing
August 2003

Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange.

Blood 2002 Oct;100(7):2472-8

Coagulation Laboratory, Institute of Hematology, Rabin Medical Center-Beilinson Campus, Petah-Tiqva, Israel.

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http://dx.doi.org/10.1182/blood-2001-12-0339DOI Listing
October 2002