Kerry L Burnstein

Kerry L Burnstein

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Kerry L Burnstein

Kerry L Burnstein

Publications by authors named "Kerry L Burnstein"

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Alterations of tumor microenvironment by nitric oxide impedes castration-resistant prostate cancer growth.

Proc Natl Acad Sci U S A 2018 10 15;115(44):11298-11303. Epub 2018 Oct 15.

Department of Urology, Miller School of Medicine, University of Miami, Miami, FL 33136;

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http://dx.doi.org/10.1073/pnas.1812704115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217394PMC
October 2018

Identification of an oncogenic network with prognostic and therapeutic value in prostate cancer.

Mol Syst Biol 2018 08 14;14(8):e8202. Epub 2018 Aug 14.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL, USA

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http://dx.doi.org/10.15252/msb.20188202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684952PMC
August 2018

Targeting AR Variant-Coactivator Interactions to Exploit Prostate Cancer Vulnerabilities.

Mol Cancer Res 2017 11 15;15(11):1469-1480. Epub 2017 Aug 15.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770277PMC
November 2017

Edelfosine Promotes Apoptosis in Androgen-Deprived Prostate Tumors by Increasing ATF3 and Inhibiting Androgen Receptor Activity.

Mol Cancer Ther 2016 06 4;15(6):1353-63. Epub 2016 Mar 4.

Department of Radiation Oncology, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, Florida.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933508PMC
June 2016

A novel calcium-dependent mechanism of acquired resistance to IGF-1 receptor inhibition in prostate cancer cells.

Oncotarget 2014 Oct;5(19):9007-21

Department of Molecular and Cellular Pharmacology, University of Miami, Miller School of Medicine, Miami, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253414PMC
http://dx.doi.org/10.18632/oncotarget.2346DOI Listing
October 2014

Coactivator MYST1 regulates nuclear factor-κB and androgen receptor functions during proliferation of prostate cancer cells.

Mol Endocrinol 2014 Jun 4;28(6):872-85. Epub 2014 Apr 4.

Department of Structural and Chemical Biology (A.J., S.M.) and Division of Hematology and Medical Oncology (P.C.), Department of Medicine, Tisch Cancer Institute, and Division of Endocrinology (S.Y., A.C.L.), Department of Medicine, Mt. Sinai School of Medicine, New York, New York 10029; University of Rochester Medical Center School of Medicine and Dentistry (G.-Q.X.), Department of Pathology and Laboratory Medicine, Rochester, New York 14642; Department of Biology (M.P., S.M.), Medgar Evers College, Brooklyn, New York 11225; State Key Laboratory of Medical Molecular Biology (X.L., D.-P.L.), Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100005, People's Republic of China; and Department of Molecular and Cellular Pharmacology (K.L.B.), Miller School of Medicine, University of Miami, Miami, Florida 33136.

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http://dx.doi.org/10.1210/me.2014-1055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042067PMC
June 2014

Preclinical efficacy of growth hormone-releasing hormone antagonists for androgen-dependent and castration-resistant human prostate cancer.

Proc Natl Acad Sci U S A 2014 Jan 6;111(3):1084-9. Epub 2014 Jan 6.

Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136.

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http://dx.doi.org/10.1073/pnas.1323102111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903215PMC
January 2014

The microRNA -23b/-27b cluster suppresses the metastatic phenotype of castration-resistant prostate cancer cells.

PLoS One 2012 26;7(12):e52106. Epub 2012 Dec 26.

Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052106PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530545PMC
July 2013

Targeting IGF-IR with ganitumab inhibits tumorigenesis and increases durability of response to androgen-deprivation therapy in VCaP prostate cancer xenografts.

Mol Cancer Ther 2013 Apr 24;12(4):394-404. Epub 2013 Jan 24.

Department of Molecular and Cellular Pharmacology, University of Miami, Miller School of Medicine, 1600 NW 10th Ave, Miami, FL 33136, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644513PMC
April 2013

Novel interaction between the co-chaperone Cdc37 and Rho GTPase exchange factor Vav3 promotes androgen receptor activity and prostate cancer growth.

J Biol Chem 2013 Feb 31;288(8):5463-74. Epub 2012 Dec 31.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1074/jbc.M112.390963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581368PMC
February 2013

Vav3 enhances androgen receptor splice variant activity and is critical for castration-resistant prostate cancer growth and survival.

Mol Endocrinol 2012 Dec 28;26(12):1967-79. Epub 2012 Sep 28.

University of Miami Miller School of Medicine, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1210/me.2012-1165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517715PMC
December 2012

In vivo 17β-estradiol treatment contributes to podocyte actin stabilization in female db/db mice.

Endocrinology 2012 Dec 15;153(12):5888-95. Epub 2012 Oct 15.

Study Group and Laboratory on Sex and Gender Differences in Health and Disease, University of Miami, Miami, FL 33136, USA.

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http://dx.doi.org/10.1210/en.2012-1637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512061PMC
December 2012

Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer.

Endocr Relat Cancer 2011 Apr 23;18(2):207-19. Epub 2011 Feb 23.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, 1600 Northwest 10th Avenue (R-189), Miami, Florida 33136, USA.

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http://dx.doi.org/10.1677/ERC-10-0049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644524PMC
April 2011

GADD45gamma: a new vitamin D-regulated gene that is antiproliferative in prostate cancer cells.

Endocrinology 2010 Oct 25;151(10):4654-64. Epub 2010 Aug 25.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, 1600 NW 10th Avenue, R-189, Room 6155 Rosenstiel Building, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1210/en.2010-0434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946153PMC
October 2010

Nuclear targeting of cyclin-dependent kinase 2 reveals essential roles of cyclin-dependent kinase 2 localization and cyclin E in vitamin D-mediated growth inhibition.

Endocrinology 2010 Mar 10;151(3):896-908. Epub 2010 Feb 10.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, 1600 NW 10th Avenue, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1210/en.2009-1116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840684PMC
March 2010

Inhibition of androgen receptor transcriptional activity as a novel mechanism of action of arsenic.

Mol Endocrinol 2009 Mar 8;23(3):412-21. Epub 2009 Jan 8.

1600 Northwest Tenth Avenue (R-189), Miami, Florida 33136, USA.

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http://dx.doi.org/10.1210/me.2008-0235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654516PMC
March 2009

Endothelin-1 enhances the expression of the androgen receptor via activation of the c-myc pathway in prostate cancer cells.

Mol Carcinog 2009 Feb;48(2):141-9

Urologic Oncology Laboratory, Department of Urology, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1002/mc.20462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280021PMC
February 2009

Ligand-independent activation of androgen receptors by Rho GTPase signaling in prostate cancer.

Mol Endocrinol 2008 Mar 13;22(3):597-608. Epub 2007 Dec 13.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1210/me.2007-0158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262175PMC
March 2008

International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors.

Pharmacol Rev 2006 Dec;58(4):782-97

Molecular Endocrinology Group, Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1124/pr.58.4.9DOI Listing
December 2006

Vav3, a Rho GTPase guanine nucleotide exchange factor, increases during progression to androgen independence in prostate cancer cells and potentiates androgen receptor transcriptional activity.

Mol Endocrinol 2006 May 29;20(5):1061-72. Epub 2005 Dec 29.

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, 1600 Northwest 10th Avenue, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1210/me.2005-0346DOI Listing
May 2006

Regulation of androgen receptor levels: implications for prostate cancer progression and therapy.

J Cell Biochem 2005 Jul;95(4):657-69

Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida, USA.

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http://dx.doi.org/10.1002/jcb.20460DOI Listing
July 2005

Androgen-induced mineralization by MC3T3-E1 osteoblastic cells reveals a critical window of hormone responsiveness.

Biochem Biophys Res Commun 2005 Mar;328(3):783-9

Geriatric Research, Education, and Clinical Center and Research Service, Veterans Affairs Medical Center, Miami, FL, USA.

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http://dx.doi.org/10.1016/j.bbrc.2004.12.090DOI Listing
March 2005

Deregulation of the Rho GTPase, Rac1, suppresses cyclin-dependent kinase inhibitor p21(CIP1) levels in androgen-independent human prostate cancer cells.

Oncogene 2004 Jul;23(32):5513-22

Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, 1600 NW 10th Avenue, Miami, FL 33136, USA.

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http://dx.doi.org/10.1038/sj.onc.1207708DOI Listing
July 2004

Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3.

Carcinogenesis 2004 Jun 23;25(6):1015-26. Epub 2004 Jan 23.

Department of Cancer Biology, Comprehensive Cancer Center of Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1093/carcin/bgh086DOI Listing
June 2004

Hormone resistance: it's SMRT to fight repression.

Endocrinology 2004 Apr;145(4):1525-6

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http://dx.doi.org/10.1210/en.2004-0003DOI Listing
April 2004

Antiandrogenic activity of extracts of diesel exhaust particles emitted from diesel-engine truck under different engine loads and speeds.

Toxicology 2004 Feb;195(2-3):243-54

Graduate School of Natural Science and Technology, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934, Japan.

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http://dx.doi.org/10.1016/j.tox.2003.10.011DOI Listing
February 2004

Evaluation of vitamin D analogs as therapeutic agents for prostate cancer.

Recent Results Cancer Res 2003 ;164:273-88

Department of Medicine, Endocrine Section, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA.

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http://dx.doi.org/10.1007/978-3-642-55580-0_20DOI Listing
December 2003

Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells.

Toxicol Sci 2003 Dec 11;76(2):299-309. Epub 2003 Sep 11.

Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa 920-0934, Japan.

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http://dx.doi.org/10.1093/toxsci/kfg230DOI Listing
December 2003

Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm.

J Biol Chem 2003 Nov 3;278(47):46862-8. Epub 2003 Sep 3.

Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, FL 33136, USA.

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http://dx.doi.org/10.1074/jbc.M306340200DOI Listing
November 2003

A role of aryl hydrocarbon receptor in the antiandrogenic effects of polycyclic aromatic hydrocarbons in LNCaP human prostate carcinoma cells.

Arch Toxicol 2003 Jun 12;77(6):335-43. Epub 2003 Mar 12.

Graduate School of Natural Science and Technology, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-0934, Japan.

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http://dx.doi.org/10.1007/s00204-003-0454-yDOI Listing
June 2003

25-Hydroxyvitamin D-1alpha-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer.

J Steroid Biochem Mol Biol 2002 Jun;81(2):135-40

Department of Medicine, Vitamin D, Skin and Bone Research Laboratory, Endocrine Section, Boston University School of Medicine, Boston, MA 02118, USA.

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http://dx.doi.org/10.1016/s0960-0760(02)00053-5DOI Listing
June 2002

Vitamin D-mediated growth inhibition of an androgen-ablated LNCaP cell line model of human prostate cancer.

Mol Cell Endocrinol 2002 Jan;186(1):69-79

Department of Molecular and Cellular Pharmacology (R-189), University of Miami School of Medicine, PO Box 016189 (R-189), Miami, FL 33136, USA.

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http://dx.doi.org/10.1016/s0303-7207(01)00671-2DOI Listing
January 2002