Keren Yizhak

Keren Yizhak

UNVERIFIED PROFILE

Are you Keren Yizhak?   Register this Author

Register author
Keren Yizhak

Keren Yizhak

Publications by authors named "Keren Yizhak"

Are you Keren Yizhak?   Register this Author

24Publications

844Reads

21Profile Views

Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer.

Cell 2017 Dec 30;171(7):1611-1624.e24. Epub 2017 Nov 30.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674173127
Publisher Site
http://dx.doi.org/10.1016/j.cell.2017.10.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878932PMC
December 2017

Essential Genes Embody Increased Mutational Robustness to Compensate for the Lack of Backup Genetic Redundancy.

PLoS One 2016 20;11(12):e0168444. Epub 2016 Dec 20.

School of Computer Sciences and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168444PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173180PMC
June 2017

A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer.

Sci Rep 2016 07 13;6:29662. Epub 2016 Jul 13.

Center for Bioinformatics and Computational Biology and the Department of Computer Science, University of Maryland, College Park 20742, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep29662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942812PMC
July 2016

Integrating transcriptomics with metabolic modeling predicts biomarkers and drug targets for Alzheimer's disease.

PLoS One 2014 15;9(8):e105383. Epub 2014 Aug 15.

The Sackler School of Medicine - Tel Aviv University, Tel Aviv, Israel; The Blavatnik School of Computer Science - Tel Aviv University, Tel Aviv, Israel.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105383PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134302PMC
December 2015

Modeling cancer metabolism on a genome scale.

Mol Syst Biol 2015 Jun 30;11(6):817. Epub 2015 Jun 30.

The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, USA

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501850PMC
http://dx.doi.org/10.15252/msb.20145307DOI Listing
June 2015

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration.

Mol Syst Biol 2014 Aug 1;10:744. Epub 2014 Aug 1.

The Blavatnik School of Computer Science, Tel-Aviv University, Tel-Aviv, Israel The Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299514PMC
http://dx.doi.org/10.15252/msb.20134993DOI Listing
August 2014

Model-based identification of drug targets that revert disrupted metabolism and its application to ageing.

Nat Commun 2013 ;4:2632

The Blavatnik School of Computer Science, Tel-Aviv University, Tel-Aviv 69978, Israel.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ncomms3632
Publisher Site
http://dx.doi.org/10.1038/ncomms3632DOI Listing
June 2014

Metabolically re-modeling the drug pipeline.

Curr Opin Pharmacol 2013 Oct 31;13(5):778-85. Epub 2013 May 31.

School of Computer Sciences, Tel Aviv University, Tel Aviv 69978, Israel; The Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coph.2013.05.006DOI Listing
October 2013

p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production.

Cancer Metab 2013 Feb 4;1(1). Epub 2013 Feb 4.

Department of Molecular Cell Biology, Weizmann Institute of Science, 234 Herzl Street, Rehovot, 76100, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/2049-3002-1-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178212PMC
February 2013

Metabolic modeling of endosymbiont genome reduction on a temporal scale.

Mol Syst Biol 2011 Mar;7:479

The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/msb.2011.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094061PMC
March 2011

Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model.

Bioinformatics 2010 Jun;26(12):i255-60

The Blavatnik School of Computer Science, Tel Aviv University, Tel-Aviv 69978, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btq183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881368PMC
June 2010