Publications by authors named "Kentaro Iwasa"

5 Publications

  • Page 1 of 1

Acquired agminated melanocytic nevus in the acral area is a potential mimicker of acral lentiginous melanoma: A three-case series report and published work review.

J Dermatol 2020 Jul 4;47(7):770-773. Epub 2020 May 4.

Department of Dermatology, Nara Medical University School of Medicine, Kashihara, Japan.

Agminated nevus refers to a clustered group of melanocytic nevi confined to a localized area of the body. It rarely involves acral skin, but recognition of acquired agminated nevus (AAN) in the acral area is clinically important because it may mimic acral lentiginous melanoma (ALM). However, acral AAN has only been described in a few case reports and its clinical characteristics remain unclear. We report three additional cases of acral AAN to further analyze the differential points between ALM. Clinical images, including those of dermoscopy, of three cases of acral AAN were reviewed. The lesions were located on the sole or lateral border of the foot. All acral AAN were flat and large in size (>20 mm in greatest dimension), and associated with asymmetry and irregular border. However, no parallel ridge pattern suggesting ALM was observed on dermoscopy. In two patients, the lesions on the sole were totally resected; microscopic evaluation of these two lesions confirmed junctional nests of banal melanocytes. AAN lesions on the sole with chronic mechanical pressure are slightly larger and more diffuse; thus, they may be more likely to be overdiagnosed as malignancy upon inspection than those in the non-acral area. Understanding the concept of the disease and careful dermoscopic evaluation leads to an accurate diagnosis.
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http://dx.doi.org/10.1111/1346-8138.15353DOI Listing
July 2020

Postpartum pruritic urticarial papules and plaques of pregnancy with blister formation resembling herpes gestationis.

Eur J Dermatol 2019 12;29(6):669-671

Department of Dermatology, Nara Medical University School of Medicine, 840 Shijo, Kashihara, Nara 634-8522.

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http://dx.doi.org/10.1684/ejd.2019.3669DOI Listing
December 2019

Revival of favus in Japan caused by Trichophyton schoenleinii.

J Dermatol 2019 Apr 15;46(4):347-350. Epub 2019 Feb 15.

Department of Dermatology, Nara Medical University, Kashihara, Japan.

Favus is a type of dermatophytosis known to produce yellow scutula around hair follicles. Most cases of this disease worldwide are infections of Trichophyton schoenleinii. Favus has rarely been reported in Japan throughout the last four decades, and T. schoenleinii has not been clinically isolated in any case during the period. Here, we report a case of favus of vellus hair observed in a 63-year-old Japanese woman. Fungal culture showed negative; however, we detected fungal elements in the crust and hair bulbs by Grocott staining. Pathogenic fungi were identified as T. schoenleinii by polymerase chain reaction-based DNA sequencing, targeting the internal transcribed spacer regions of the rRNA gene using the formalin-fixed, paraffin-embedded tissue sample. She was successfully treated with p.o. administration of terbinafine and topical application of luliconazole cream.
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http://dx.doi.org/10.1111/1346-8138.14804DOI Listing
April 2019

A molybdenum complex bearing a tetraphosphine ligand as a precursor for heterobimetallic complexes.

Dalton Trans 2014 Jun;43(24):9344-55

Institute of Industrial Science, The University of Tokyo, Komaba, Meguro-ku, Tokyo 153-8505, Japan.

The reactions of [CpMoH(κ(3)-P4)] (2; P4 = meso-o-C6H4(PPhCH2CH2PPh2)2) with protic acids gave [CpMo(κ(4)-P4)](+) (4(+)) via the intermediary formation of [CpMoH2(κ(3)-P4)](+). Treatment of 2 with iodine provided the cationic complex [CpMoHI(κ(3)-P4)][I] (5[I]). Early-late heterobimetallic complexes of the type [CpMoH(μ-P4-1κ(3):2κ)MLnCl] (MLn = Ru(Hmb)Cl (6), Ir(η(5)-C5Me5)Cl (7), Rh(cod), Ir(cod), Pd(η(3)-C3H5) (10); Hmb = η(6)-C6Me6, cod = η(4)-1,5-cyclooctadiene) were synthesised by reacting 2 with [MLn(μ-Cl)]2, and their structures were characterised by NMR spectroscopy. The hydride ligand in 6 was replaced by chloride in chlorinated organic solvents to give [CpMoCl(μ-P4-1κ(3):2κ)Ru(Hmb)Cl2] (11). Self-reaction of 10 produced allylbenzene and [CpMo(μ-H){μ-PhP(CH2)2P(Ph)-o-C6H4-P(Ph)(CH2)2PPh2-1κ(3):2κ(2)}PdCl] (12), in which the Mo-Pd edge was bridged by a hydride ligand and the phosphide moiety emerged from the loss of one phenyl group. The molecular structures of 4[Cl], 4[OTf], 5[I], 6, 7, 11, and 12 were established by single-crystal X-ray analysis.
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http://dx.doi.org/10.1039/c4dt00581cDOI Listing
June 2014

Preparation of a bis(hydrosulfido) complex of Mo having a tetraphosphine co-ligand and its transformation into MoRh2 and MoIr2 mixed-metal sulfido clusters.

Dalton Trans 2009 Aug 4(31):6134-40. Epub 2009 Jun 4.

Institute of Industrial Science, The University of Tokyo, Komaba, Meguro-ku, Tokyo 153-8505, Japan.

The treatment of a Mo(0) complex with a tetraphosphine co-ligand [Mo(kappa(4)-P4)(Ph(2)PCH(2)CH(2)PPh(2))] (P4 = meso-o-C(6)H(4)(PPhCH(2)CH(2)PPh(2))(2)) with H(2)S gas in toluene at room temperature afforded [Mo(SH)(2)(kappa(4)-P4)] (1), which demonstrates the first Mo(II) bis(hydrosulfido) complex. Its trigonal-prismatic structure rarely observed for Mo(II) complexes has been determined by X-ray analysis. The reactions of 1 with [RhCl(CO)(2)](2) and [IrCl(CO)(2)(p-toluidine)] in the presence of NEt(3) resulted in the formation of the sulfido-bridged trinuclear clusters [Mo(kappa(4)-P4)(mu(3)-S)(2){Rh(CO)(2)}(2)] (4) and [Mo(kappa(4)-P4)(mu(3)-S)(2){Ir(CO)(2)}(2)] (5), respectively. The X-ray diffraction study has disclosed that the MoRh(2) cluster 4 in the solid state exists in two isomeric forms arising from the different orientation of P4 to the trigonal-prismatic Mo center, whereas the crystals of the Ir analogue 5 contains the molecules corresponding to only one of the two isomers observed for 4. The fluxional features of 1, 4, and 5 in solution have been confirmed by VT NMR studies.
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http://dx.doi.org/10.1039/b902386kDOI Listing
August 2009