Publications by authors named "Kent W Mouw"

66Publications

Editorial: Bladder Cancer - A Cinderella Cancer: Advances and Remaining Research Questions.

Front Oncol 2020 4;10:1749. Epub 2020 Sep 4.

Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham & Women's Hospital and Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.3389/fonc.2020.01749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499472PMC
September 2020

Development and Validation of a Novel TP53 Mutation Signature That Predicts Risk of Metastasis in Primary Prostate Cancer.

Clin Genitourin Cancer 2020 Aug 13. Epub 2020 Aug 13.

Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA.

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http://dx.doi.org/10.1016/j.clgc.2020.08.004DOI Listing
August 2020

Relative Timing of Radiotherapy and Androgen Deprivation for Prostate Cancer and Implications for Treatment During the COVID-19 Pandemic.

JAMA Oncol 2020 Aug 13. Epub 2020 Aug 13.

Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaoncol.2020.3545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426885PMC
August 2020

Impact of percent positive biopsy cores on cancer-specific mortality for patients with high-risk prostate cancer.

Urol Oncol 2020 Sep 10;38(9):735.e9-735.e15. Epub 2020 Jul 10.

Harvard Medical School, Boston, MA; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2020.05.023DOI Listing
September 2020

Doublecortin Expression in Prostate Adenocarcinoma and Neuroendocrine Tumors.

Int J Radiat Oncol Biol Phys 2020 Nov 22;108(4):936-940. Epub 2020 Jun 22.

Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ijrobp.2020.06.024DOI Listing
November 2020

Validation of a subclassification for high-risk prostate cancer in a prospective cohort.

Cancer 2020 May 19;126(10):2132-2138. Epub 2020 Feb 19.

Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.32778DOI Listing
May 2020

Practice Patterns and Outcomes Among Patients With N0M0 Prostate Cancer and a Very High Prostate-Specific Antigen Level.

J Natl Compr Canc Netw 2019 08;17(8):941-948

Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.6004/jnccn.2018.7283DOI Listing
August 2019

Genomic Validation of 3-Tiered Clinical Subclassification of High-Risk Prostate Cancer.

Int J Radiat Oncol Biol Phys 2019 11 2;105(3):621-627. Epub 2019 Jul 2.

Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ijrobp.2019.06.2510DOI Listing
November 2019

Use and early mortality outcomes of active surveillance in patients with intermediate-risk prostate cancer.

Cancer 2019 09 31;125(18):3164-3171. Epub 2019 May 31.

Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.32202DOI Listing
September 2019

Reply from Authors re: Ananya Choudhury, Peter J. Hoskin. Predictive Biomarkers for Muscle-invasive Bladder Cancer: The Search for the Holy Grail Continues. Eur Urol 2019;76:69-70: Towards Biomarker-Informed Management of Muscle-Invasive Bladder Cancer.

Eur Urol 2019 07 23;76(1):71-72. Epub 2019 Mar 23.

Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2019.03.009DOI Listing
July 2019

Assessing the Training and Research Environment for Genomics, Bioinformatics, and Immunology in Radiation Oncology.

JCO Clin Cancer Inform 2018 12;2:1-9

Kent W. Mouw, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA; Tyler F. Beck and Judith C. Keen, American Society for Radiation Oncology, Arlington, VA; and Adam P. Dicker, Sidney Kimmel Medical College and Cancer Center, Thomas Jefferson University, Philadelphia, PA.

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http://dx.doi.org/10.1200/CCI.18.00045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874041PMC
December 2018

A comparative analysis of overall survival between high-dose-rate and low-dose-rate brachytherapy boosts for unfavorable-risk prostate cancer.

Brachytherapy 2019 Mar - Apr;18(2):186-191. Epub 2019 Jan 10.

Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, MA; Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.brachy.2018.12.007DOI Listing
July 2019

Androgen Deprivation Therapy and Overall Survival for Gleason 8 Versus Gleason 9-10 Prostate Cancer.

Eur Urol 2019 01 24;75(1):35-41. Epub 2018 Oct 24.

Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.08.033DOI Listing
January 2019

Molecular biomarkers in bladder preservation therapy for muscle-invasive bladder cancer.

Lancet Oncol 2018 12;19(12):e683-e695

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(18)30693-4DOI Listing
December 2018

Toward Biomarker-Informed Trimodality Therapy (TMT) Approaches for Muscle-Invasive Bladder Cancer.

Authors:
Kent W Mouw

Int J Radiat Oncol Biol Phys 2018 12 10;102(5):1417-1419. Epub 2018 Aug 10.

Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2018.07.2020DOI Listing
December 2018

Applying Precision Oncology Principles in Radiation Oncology.

JCO Precis Oncol 2018 14;2. Epub 2018 May 14.

and , Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School; and , Harvard Radiation Oncology Program, Boston, MA.

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http://dx.doi.org/10.1200/PO.18.00034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446508PMC
May 2018

DNA Repair Deficiency and Immunotherapy Response.

J Clin Oncol 2018 06 23;36(17):1710-1713. Epub 2018 Apr 23.

Kent W. Mouw, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, MA; and Alan D. D'Andrea, Dana-Farber Cancer Institute, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2018.78.2425DOI Listing
June 2018

From checkpoint to checkpoint: DNA damage ATR/Chk1 checkpoint signalling elicits PD-L1 immune checkpoint activation.

Br J Cancer 2018 04 13;118(7):933-935. Epub 2018 Mar 13.

Gynecologic Medical Oncology Program, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA.

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http://www.nature.com/articles/s41416-018-0017-x
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http://dx.doi.org/10.1038/s41416-018-0017-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931110PMC
April 2018

Clinical and Genomic Characterization of Low-Prostate-specific Antigen, High-grade Prostate Cancer.

Eur Urol 2018 08 22;74(2):146-154. Epub 2018 Feb 22.

Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615042PMC
August 2018

Impact of a dedicated palliative radiation oncology service on the use of single fraction and hypofractionated radiation therapy among patients with bone metastases.

Ann Palliat Med 2018 Apr 30;7(2):186-191. Epub 2017 Nov 30.

Department of Radiation Oncology and Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.21037/apm.2017.11.02DOI Listing
April 2018

Brachytherapy monotherapy may be sufficient for a subset of patients with unfavorable intermediate risk prostate cancer.

Urol Oncol 2018 04 21;36(4):157.e15-157.e20. Epub 2017 Dec 21.

Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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https://linkinghub.elsevier.com/retrieve/pii/S10781439173061
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http://dx.doi.org/10.1016/j.urolonc.2017.11.022DOI Listing
April 2018

Pathologic Outcomes of Gleason 6 Favorable Intermediate-Risk Prostate Cancer Treated With Radical Prostatectomy: Implications for Active Surveillance.

Clin Genitourin Cancer 2018 06 9;16(3):226-234. Epub 2017 Nov 9.

Harvard Medical School, Boston, MA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2017.10.013DOI Listing
June 2018

Lack of Benefit From the Addition of External Beam Radiation Therapy to Brachytherapy for Intermediate- and High-risk Prostate Cancer.

Int J Radiat Oncol Biol Phys 2017 11 31;99(4):904-911. Epub 2017 Jul 31.

Harvard Medical School, Boston, Massachusetts; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2017.07.034DOI Listing
November 2017

DNA Damage and Repair Biomarkers of Immunotherapy Response.

Cancer Discov 2017 07 19;7(7):675-693. Epub 2017 Jun 19.

Department of Radiation Oncology, Brigham & Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659200PMC
July 2017

DNA Repair Pathway Alterations in Bladder Cancer.

Authors:
Kent W Mouw

Cancers (Basel) 2017 Mar 27;9(4). Epub 2017 Mar 27.

Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.3390/cancers9040028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406703PMC
March 2017

Post-Prostatectomy Radiation Therapy: Balancing Disease Control and Functional Outcomes.

J Urol 2017 03 16;197(3 Pt 1):541-542. Epub 2016 Dec 16.

Department of Radiation Oncology, Brigham & Women's Hospital/Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.juro.2016.12.023DOI Listing
March 2017

A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance.

Cancer Res 2015 Feb 29;75(4):628-34. Epub 2015 Jan 29.

Department of Medical Oncology, Medical Gynecologic Oncology Program, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-14-2593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416405PMC
February 2015

Proton radiation therapy for the treatment of retinoblastoma.

Int J Radiat Oncol Biol Phys 2014 Nov 13;90(4):863-9. Epub 2014 Sep 13.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2014.07.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253018PMC
November 2014

Crosstalk between the nucleotide excision repair and Fanconi anemia/BRCA pathways.

DNA Repair (Amst) 2014 Jul 24;19:130-4. Epub 2014 Apr 24.

Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2014.03.019DOI Listing
July 2014

Hypofractionation in the era of modulated radiotherapy (RT).

Breast 2013 Aug;22 Suppl 2:S129-36

Harvard Radiation Oncology Program, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.breast.2013.07.024DOI Listing
August 2013

Arginine as a general acid catalyst in serine recombinase-mediated DNA cleavage.

J Biol Chem 2013 Oct 22;288(40):29206-14. Epub 2013 Aug 22.

From the Department of Biochemistry and Molecular Biology and.

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http://dx.doi.org/10.1074/jbc.M113.508028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790019PMC
October 2013

Clinical controversies: proton therapy for prostate cancer.

Semin Radiat Oncol 2013 Apr;23(2):109-14

Harvard Radiation Oncology Program, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.semradonc.2012.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595123PMC
April 2013

Irradiation in early-stage breast cancer: conventional whole-breast, accelerated partial-breast, and accelerated whole-breast strategies compared.

Oncology (Williston Park) 2012 Sep;26(9):820-30

Harvard Radiation Oncology Program, Boston, Massachusetts, USA.

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September 2012

Performance and quality of life outcomes for T4 laryngeal cancer patients treated with induction chemotherapy followed by chemoradiotherapy.

Oral Oncol 2012 Oct 22;48(10):1025-1030. Epub 2012 May 22.

Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, United States; Comprehensive Cancer Center, University of Chicago, Chicago, IL, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2012.04.004DOI Listing
October 2012

Sin resolvase catalytic activity and oligomerization state are tightly coupled.

J Mol Biol 2010 Nov 22;404(1):16-33. Epub 2010 Sep 22.

Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.jmb.2010.08.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976518PMC
November 2010

Orchestrating serine resolvases.

Biochem Soc Trans 2010 Apr;38(2):384-7

Department of Biochemistry and Molecular Biology, University of Chicago, 929 E. 57th Street, Chicago, IL 60615, USA.

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http://dx.doi.org/10.1042/BST0380384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775659PMC
April 2010

Regulatory mutations in Sin recombinase support a structure-based model of the synaptosome.

Mol Microbiol 2009 Oct 8;74(2):282-98. Epub 2009 Jun 8.

University of Glasgow, FBLS, Division of Molecular Genetics, Glasgow, Scotland, UK.

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http://dx.doi.org/10.1111/j.1365-2958.2009.06756.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764113PMC
October 2009

Architecture of a serine recombinase-DNA regulatory complex.

Mol Cell 2008 Apr;30(2):145-55

Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.molcel.2008.02.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428073PMC
April 2008

Shaping the Borrelia burgdorferi genome: crystal structure and binding properties of the DNA-bending protein Hbb.

Mol Microbiol 2007 Mar 22;63(5):1319-30. Epub 2007 Jan 22.

Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/j.1365-2958.2007.05586.xDOI Listing
March 2007