Kenneth P Olive

Kenneth P Olive

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Kenneth P Olive

Kenneth P Olive

Publications by authors named "Kenneth P Olive"

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Laser Capture Microdissection on Frozen Sections for Extraction of High-Quality Nucleic Acids.

Methods Mol Biol 2019 ;1882:253-259

Department of Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8879-2_23DOI Listing
June 2019

Modeling Pancreatic Cancer through Somatic Editing with AAV.

Trends Mol Med 2019 May 13;25(5):361-362. Epub 2019 Mar 13.

Department of Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2019.02.012DOI Listing
May 2019

Current and Emerging Therapies in Metastatic Pancreatic Cancer.

Clin Cancer Res 2017 Apr;23(7):1670-1678

Division of Medical Oncology, Columbia University Medical Center, and New York Presbyterian Hospital, Herbert Irving Pavilion, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2319DOI Listing
April 2017

Pancreatic Cancer: Progress and Challenges in a Rapidly Moving Field.

Cancer Res 2017 03 16;77(5):1060-1062. Epub 2017 Feb 16.

Department of Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2452DOI Listing
March 2017

Fanning the Flames of Cancer Chemoresistance: Inflammation and Anticancer Therapy.

Authors:
Kenneth P Olive

J Oncol Pract 2017 03;13(3):181-183

Columbia University Medical Center, New York, NY.

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http://dx.doi.org/10.1200/JOP.2017.021154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456258PMC
March 2017

Stroma, Stroma Everywhere (Far More Than You Think).

Authors:
Kenneth P Olive

Clin Cancer Res 2015 Aug 15;21(15):3366-8. Epub 2015 May 15.

Division of Digestive and Liver Diseases, Department of Medicine and Department of Pathology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0416DOI Listing
August 2015

Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.

Carcinogenesis 2015 Jul 4;36(7):730-8. Epub 2015 May 4.

Department of Surgery, Program in Cell and Molecular Biology, Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA and

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http://dx.doi.org/10.1093/carcin/bgv058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566095PMC
July 2015

Preclinical pharmacologic evaluation of pralatrexate and romidepsin confirms potent synergy of the combination in a murine model of human T-cell lymphoma.

Clin Cancer Res 2015 May 12;21(9):2096-106. Epub 2015 Feb 12.

Center for Lymphoid Malignancies, Columbia University Medical Center, New York, New York. Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York. Department of Medicine, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2249DOI Listing
May 2015

Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.

Sci Transl Med 2015 Jan;7(271):271ra7

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Center for Molecular Imaging and Nanotechnology (CMINT), Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Department of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1126/scitranslmed.3010633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414254PMC
January 2015

Protein breakdown precedes pancreatic tumor development.

Nat Med 2014 Oct;20(10):1097-9

Herbert Irving Comprehensive Cancer Center and at the Departments of Medicine and Pathology &Cell Biology, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.3714DOI Listing
October 2014

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.

Cancer Cell 2014 Jun 22;25(6):735-47. Epub 2014 May 22.

Gastroenterology Division, Department of Medicine and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096698PMC
June 2014

Translational therapeutics in genetically engineered mouse models of cancer.

Cold Spring Harb Protoc 2014 Feb 1;2014(2):131-43. Epub 2014 Feb 1.

Departments of Medicine and Pathology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York 10032;

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http://dx.doi.org/10.1101/pdb.top069997DOI Listing
February 2014

Identification and manipulation of biliary metaplasia in pancreatic tumors.

Gastroenterology 2014 Jan 30;146(1):233-44.e5. Epub 2013 Aug 30.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida. Electronic address:

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http://www.olivelab.org/uploads/6/3/6/2/6362060/2014_-_gastr
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http://linkinghub.elsevier.com/retrieve/pii/S001650851301273
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http://dx.doi.org/10.1053/j.gastro.2013.08.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870045PMC
January 2014

Acquisition of mouse tumor biopsies through abdominal laparotomy.

Cold Spring Harb Protoc 2014 Jan 1;2014(1):47-56. Epub 2014 Jan 1.

Department of Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York 10032;

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http://dx.doi.org/10.1101/pdb.prot077834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084730PMC
January 2014

Genetically engineered mouse models of pancreatic cancer.

Cancer J 2012 Nov-Dec;18(6):502-10

Department of Medicine, Columbia University Medical Center, New York, NY, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PPO.0b013e31827ab4c4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594661PMC
August 2013

Quantification of murine pancreatic tumors by high-resolution ultrasound.

Methods Mol Biol 2013 ;980:249-66

Herbery Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-62703-287-2_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879959PMC
July 2013

Pancreatic cancer: why is it so hard to treat?

Therap Adv Gastroenterol 2013 Jul;6(4):321-37

Department of Medicine, Division of Hematology and Oncology, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1177/1756283X13478680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667471PMC
July 2013

Recapitulating human cancer in a mouse.

Nat Biotechnol 2013 May;31(5):392-5

Department of Genomic Medicine, and the Institute for Applied Cancer Science, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1038/nbt.2575DOI Listing
May 2013

Silencing the killers: paracrine immune suppression in pancreatic cancer.

Cancer Cell 2012 Jun;21(6):715-6

Departments of Radiation Oncology and Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.05.029DOI Listing
June 2012

Stromal biology and therapy in pancreatic cancer.

Gut 2011 Jun 21;60(6):861-8. Epub 2010 Oct 21.

Li Ka Shing Centre, Cambridge Research Institute, Cancer Research UK, Cambridge, UK.

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http://gut.bmj.com/cgi/doi/10.1136/gut.2010.226092
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http://dx.doi.org/10.1136/gut.2010.226092DOI Listing
June 2011

Germline Brca2 heterozygosity promotes Kras(G12D) -driven carcinogenesis in a murine model of familial pancreatic cancer.

Cancer Cell 2010 Nov 4;18(5):499-509. Epub 2010 Nov 4.

Department of Oncology and the Medical Research Council Cancer Cell Unit, University of Cambridge, Hills Road, Cambridge CB2 0XZ, UK.

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http://dx.doi.org/10.1016/j.ccr.2010.10.015DOI Listing
November 2010

Heterozygosity for hypoxia inducible factor 1alpha decreases the incidence of thymic lymphomas in a p53 mutant mouse model.

Cancer Res 2009 Apr 17;69(7):3213-20. Epub 2009 Mar 17.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707815PMC
April 2009

K-Ras-driven pancreatic cancer mouse model for anticancer inhibitor analyses.

Methods Enzymol 2008 ;439:73-85

Department of Clinical Oncology, Addenbrookes NHS Trust, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/S0076-6879(07)00406-5DOI Listing
June 2008

The use of targeted mouse models for preclinical testing of novel cancer therapeutics.

Clin Cancer Res 2006 Sep;12(18):5277-87

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-06-0436DOI Listing
September 2006

The differential effects of mutant p53 alleles on advanced murine lung cancer.

Cancer Res 2005 Nov;65(22):10280-8

Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02141, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-2193DOI Listing
November 2005

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.

Cancer Res 2005 Sep;65(18):8166-73

Laboratory of Toxicology, Pathology and Genetics, National Institute of Public Health and the Environment, Bilthoven, The Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1650DOI Listing
September 2005

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome.

Cell 2004 Dec;119(6):847-60

Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.cell.2004.11.004DOI Listing
December 2004